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The map label for this gene is fadE12 [H]

Identifier: 119870423

GI number: 119870423

Start: 4616178

End: 4617347

Strand: Direct

Name: fadE12 [H]

Synonym: Mkms_4394

Alternate gene names: 119870423

Gene position: 4616178-4617347 (Clockwise)

Preceding gene: 119870422

Following gene: 119870424

Centisome position: 80.46

GC content: 68.38

Gene sequence:

>1170_bases
ATGACCGGATTCGTGGAGACCGACGAACAACAGGCGCTGCGGCAGGCGGTGGCGGCGATGGCCGCCAACTACGGGCAGGA
CTACTACCTCGAGAAGGCCCGCGCCGGTGAGCACACCGACGAACTGTGGGCCGAGGCGGGCAAGCTCGGGTTCATCGGGG
TCAACCTGCCCGAGGAGTACGGCGGCGGCGGCGCAGGCATGTACGAACTGTCGCTGGTGATGGAGGAGATGGCGGCCGCC
GGGTCGGCGCTGCTGATGATGGTGGTCTCCCCCGCCATCAACGGCACGATCATCAGCAAGTTCGGCACCGACGAGCAGAA
GCGGCGGTGGCTGCCCGGCATCGCGGACGGGTCGATCACCATGGCGTTCGCGATCACCGAACCCGACGCCGGGTCGAATT
CGCACAAGATCACCACCACCGCCCGCCGCGACGGTGGCGACTGGATCCTCAACGGCCAGAAGGTCTACATCTCCGGCGTC
GACCAGGCGCAGGCGGTGCTCGTCGTGGGCCGCACTTACAGGGAGGGAGTGGCAAAGGCGGAGTCGCTACGACCCGCGCT
GTTCGTCGTGCCCACCGATACCCCGGGGCTGACGTGGACCAAGATCGAGATGGAGCTCATCAGCCCGGAGAACCAGTTCC
AGGTGTTCCTCGACGACGTCCGCCTGCCCGCCGATGCGCTCGTCGGCTCCGAGGACGCCGCGATCGCGCAACTGTTCGCG
GGGCTGAACCCGGAGCGGATCATGGGTGCGGCCAGCGCGGTGGGCATGGGCCGCTTCGCGCTGGGCCGCGCGGTCGACTA
CGTGAAGACCCGACAGGTGTGGAAGACGCCGATCGGCGCCCATCAGGGTCTGTCACATCCGCTGGCGCAGAACCATATCG
AGATCGAACTGGCCAAGCTGATGATGCAGAAGGCCGCCGCGCTCTACGACGGCGGCGACGACGCCGGGGCGGCCGAGGCC
GCGAACATGGCGAAGTACGCGGCCGGTGAGGCGTCGGTGCGCGCGGTCGATCAGGCCGTGCAGTCGATGGGTGGCAACGG
GTTGACCAAGGAGTACGGCGTCGCGGCGGCGGTGACCGCGTCCCGGCTCGCGCGCATCGCTCCGGTGAGCCGCGAGATGA
TCCTCAACTTCGTCGCGCAGACCTCGCTCGGCCTGCCCCGCTCGTACTGA

Upstream 100 bases:

>100_bases
CCGGTGACGGTGTGCTCGCCGAACTGACCGTCGCACCCGGCCAGCAGGTCGAGGTCGGCACGGTCCTGGCCCGGGTGGAG
AGCCCAGAAGGAGACGACAC

Downstream 100 bases:

>100_bases
TGAGCACCCTCGTCCGCTACGCCGTCGACGGCCCCGTCGCCCGGCTGACGCTCGACTCGCCGCAGAACCGCAACGCCCTG
TCGACCGTCCTGGTCGAGCA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTGFVETDEQQALRQAVAAMAANYGQDYYLEKARAGEHTDELWAEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAAA
GSALLMMVVSPAINGTIISKFGTDEQKRRWLPGIADGSITMAFAITEPDAGSNSHKITTTARRDGGDWILNGQKVYISGV
DQAQAVLVVGRTYREGVAKAESLRPALFVVPTDTPGLTWTKIEMELISPENQFQVFLDDVRLPADALVGSEDAAIAQLFA
GLNPERIMGAASAVGMGRFALGRAVDYVKTRQVWKTPIGAHQGLSHPLAQNHIEIELAKLMMQKAAALYDGGDDAGAAEA
ANMAKYAAGEASVRAVDQAVQSMGGNGLTKEYGVAAAVTASRLARIAPVSREMILNFVAQTSLGLPRSY

Sequences:

>Translated_389_residues
MTGFVETDEQQALRQAVAAMAANYGQDYYLEKARAGEHTDELWAEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAAA
GSALLMMVVSPAINGTIISKFGTDEQKRRWLPGIADGSITMAFAITEPDAGSNSHKITTTARRDGGDWILNGQKVYISGV
DQAQAVLVVGRTYREGVAKAESLRPALFVVPTDTPGLTWTKIEMELISPENQFQVFLDDVRLPADALVGSEDAAIAQLFA
GLNPERIMGAASAVGMGRFALGRAVDYVKTRQVWKTPIGAHQGLSHPLAQNHIEIELAKLMMQKAAALYDGGDDAGAAEA
ANMAKYAAGEASVRAVDQAVQSMGGNGLTKEYGVAAAVTASRLARIAPVSREMILNFVAQTSLGLPRSY
>Mature_388_residues
TGFVETDEQQALRQAVAAMAANYGQDYYLEKARAGEHTDELWAEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAAAG
SALLMMVVSPAINGTIISKFGTDEQKRRWLPGIADGSITMAFAITEPDAGSNSHKITTTARRDGGDWILNGQKVYISGVD
QAQAVLVVGRTYREGVAKAESLRPALFVVPTDTPGLTWTKIEMELISPENQFQVFLDDVRLPADALVGSEDAAIAQLFAG
LNPERIMGAASAVGMGRFALGRAVDYVKTRQVWKTPIGAHQGLSHPLAQNHIEIELAKLMMQKAAALYDGGDDAGAAEAA
NMAKYAAGEASVRAVDQAVQSMGGNGLTKEYGVAAAVTASRLARIAPVSREMILNFVAQTSLGLPRSY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=30.1333333333333, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI4557233, Length=308, Percent_Identity=33.7662337662338, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI226958412, Length=371, Percent_Identity=26.6846361185984, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI187960098, Length=354, Percent_Identity=27.683615819209, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4557231, Length=354, Percent_Identity=27.683615819209, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=26.8436578171091, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI4501859, Length=339, Percent_Identity=29.7935103244838, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI38505218, Length=297, Percent_Identity=29.6296296296296, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI7656849, Length=341, Percent_Identity=28.1524926686217, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI48976061, Length=322, Percent_Identity=27.9503105590062, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI211971008, Length=322, Percent_Identity=27.9503105590062, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI21361497, Length=387, Percent_Identity=26.0981912144703, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI4557235, Length=378, Percent_Identity=27.5132275132275, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI76496475, Length=378, Percent_Identity=27.5132275132275, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI4503943, Length=318, Percent_Identity=24.8427672955975, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI7669494, Length=318, Percent_Identity=24.8427672955975, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=26.525198938992, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786223, Length=371, Percent_Identity=26.1455525606469, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI87081702, Length=364, Percent_Identity=26.6483516483516, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=358, Percent_Identity=29.3296089385475, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17508101, Length=337, Percent_Identity=28.7833827893175, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17506239, Length=333, Percent_Identity=29.4294294294294, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17569725, Length=376, Percent_Identity=27.3936170212766, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17570075, Length=323, Percent_Identity=30.9597523219814, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=29.1814946619217, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=24.8677248677249, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=340, Percent_Identity=26.7647058823529, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17505929, Length=338, Percent_Identity=27.2189349112426, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17533517, Length=351, Percent_Identity=24.5014245014245, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=29.3333333333333, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=335, Percent_Identity=25.9701492537313, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=338, Percent_Identity=26.3313609467456, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=360, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=228, Percent_Identity=28.9473684210526, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24666513, Length=350, Percent_Identity=30.2857142857143, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21356377, Length=328, Percent_Identity=31.0975609756098, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=26.4705882352941, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI21355753, Length=368, Percent_Identity=26.9021739130435, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646207, Length=306, Percent_Identity=28.7581699346405, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=26, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920834, Length=363, Percent_Identity=27.8236914600551, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41289; Mature: 41158

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGFVETDEQQALRQAVAAMAANYGQDYYLEKARAGEHTDELWAEAGKLGFIGVNLPEEY
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCHHH
GGGGAGMYELSLVMEEMAAAGSALLMMVVSPAINGTIISKFGTDEQKRRWLPGIADGSIT
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCCCCCCEE
MAFAITEPDAGSNSHKITTTARRDGGDWILNGQKVYISGVDQAQAVLVVGRTYREGVAKA
EEEEEECCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCCEEEEEECCHHHHHHHHH
ESLRPALFVVPTDTPGLTWTKIEMELISPENQFQVFLDDVRLPADALVGSEDAAIAQLFA
HHCCCEEEEEECCCCCCEEEEEEEEEECCCCCEEEEEHHHCCCHHHHCCCCHHHHHHHHH
GLNPERIMGAASAVGMGRFALGRAVDYVKTRQVWKTPIGAHQGLSHPLAQNHIEIELAKL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHH
MMQKAAALYDGGDDAGAAEAANMAKYAAGEASVRAVDQAVQSMGGNGLTKEYGVAAAVTA
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHCHHHHHHH
SRLARIAPVSREMILNFVAQTSLGLPRSY
HHHHHHCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TGFVETDEQQALRQAVAAMAANYGQDYYLEKARAGEHTDELWAEAGKLGFIGVNLPEEY
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCHHH
GGGGAGMYELSLVMEEMAAAGSALLMMVVSPAINGTIISKFGTDEQKRRWLPGIADGSIT
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCCCCCCEE
MAFAITEPDAGSNSHKITTTARRDGGDWILNGQKVYISGVDQAQAVLVVGRTYREGVAKA
EEEEEECCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCCEEEEEECCHHHHHHHHH
ESLRPALFVVPTDTPGLTWTKIEMELISPENQFQVFLDDVRLPADALVGSEDAAIAQLFA
HHCCCEEEEEECCCCCCEEEEEEEEEECCCCCEEEEEHHHCCCHHHHCCCCHHHHHHHHH
GLNPERIMGAASAVGMGRFALGRAVDYVKTRQVWKTPIGAHQGLSHPLAQNHIEIELAKL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHH
MMQKAAALYDGGDDAGAAEAANMAKYAAGEASVRAVDQAVQSMGGNGLTKEYGVAAAVTA
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHCHHHHHHH
SRLARIAPVSREMILNFVAQTSLGLPRSY
HHHHHHCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]