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The map label for this gene is yngJ [H]

Identifier: 119870420

GI number: 119870420

Start: 4611341

End: 4612489

Strand: Direct

Name: yngJ [H]

Synonym: Mkms_4391

Alternate gene names: 119870420

Gene position: 4611341-4612489 (Clockwise)

Preceding gene: 119870419

Following gene: 119870421

Centisome position: 80.38

GC content: 69.1

Gene sequence:

>1149_bases
GTGAGCATCTGGGACACCCCCGAACGCGACCAGTTGCGAAAGACGGTGCGCGCGTTCGCAGACCGCGAGGTGCTTCCGCA
CGTCGACGAGTGGGAGCGCGCCGGCGAGCTGCCGCGCGAATTGCACCGCAAGGCCGGTGCGGCAGGTCTGCTCGGGGCGG
GTATGCCCGAATCGGTCGGCGGCGGTGGCGGTGACGGCGCCGACGCGGTCATCATCTGCGAAGAGATGCACTACGCCGGC
GCCCCCGGCGGGGTGTTCGCCTCGCTGTTCACCTCCGGCATCGCGACCCCGCACATGACCGCCTCGGGCGACGAGCGGTT
GATCGACACCTACGTCCGGCCCACGCTGCACGGTGAGCTGATCGGCTCGCTGGCGATCACCGAGCCGGGCGGCGGCTCCG
ACGTCGGGCACCTCACCACCCGCGCCGAACGCGACGGCGACTCGTATGTGGTCAACGGGGCCAAGACCTACATCACCTCG
GGCGTGCGCGCCGACTATGTGGTGACGGCGGTGCGCACCGGCGGCCCTGGCGCCGGCGGGGTGTCACTGCTCGTCGTCGA
CAAGGGCACCCCCGGATTCGAGGTCACCCGCAAGCTGGACAAGATGGGCTGGCGGTCCAGCGACACCGCCGAACTGTCCT
ACACCGACGTGCGCGTCCCGGCCGCCAACCTGATCGGCGCCGAGAACACCGGCTTCCTGCAGATCGCGGGCGCGTTCGTC
TCCGAGCGGGTGGGCCTTGCGGCGCAGGCGTATTCGAGCGCGCAACGCTGCCTCGACCTGACCGTGCAGTGGTGTCGAGA
CCGCGAGACCTTCGGGCGGCCGCTGATCTCCCGGCAGTCGGTGCAGAACACGCTGGCAGAGATGGCCCGCCGCGTCGACG
TCGCGCGCGTGTACACGCGCCATGTGGTGGAACGGCAACTGAGCGGGGAGACCAATCTCATCGCCGAGGTCTGCTTCGCC
AAGAACACCGCCGTCGAAGCCGGCGAATGGGTGGCCAACCAGGCCGTCCAACTGTTCGGCGGAATGGGTTACATGGCCGA
GTCCGAGGTCGAGAGGCAGTACCGCGACATGCGGATCCTCGGAATCGGCGGCGGGACCACCGAAATCCTCACCGCACTGG
CCGCCAAGACGTTGGGATATCAGGGATGA

Upstream 100 bases:

>100_bases
AGGGCGTGGCCTACCAGGCCCGGTTCGACCCGCAGGCCAAGGGGCTCGGCGAATGGTTGCGCAGCCGTCATCTCGAGATC
CCCGAGGAGGTGCTGCCCCG

Downstream 100 bases:

>100_bases
ACATGCCGAATGTGCACTCAGCGCGAGAATCGGCCGCGAAAATCGCGGTGGCTTCACACTCGGCGACGGAGGCGGCGATA
TGGCGCTGAAGTCCACGCTC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSIWDTPERDQLRKTVRAFADREVLPHVDEWERAGELPRELHRKAGAAGLLGAGMPESVGGGGGDGADAVIICEEMHYAG
APGGVFASLFTSGIATPHMTASGDERLIDTYVRPTLHGELIGSLAITEPGGGSDVGHLTTRAERDGDSYVVNGAKTYITS
GVRADYVVTAVRTGGPGAGGVSLLVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPAANLIGAENTGFLQIAGAFV
SERVGLAAQAYSSAQRCLDLTVQWCRDRETFGRPLISRQSVQNTLAEMARRVDVARVYTRHVVERQLSGETNLIAEVCFA
KNTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTALAAKTLGYQG

Sequences:

>Translated_382_residues
MSIWDTPERDQLRKTVRAFADREVLPHVDEWERAGELPRELHRKAGAAGLLGAGMPESVGGGGGDGADAVIICEEMHYAG
APGGVFASLFTSGIATPHMTASGDERLIDTYVRPTLHGELIGSLAITEPGGGSDVGHLTTRAERDGDSYVVNGAKTYITS
GVRADYVVTAVRTGGPGAGGVSLLVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPAANLIGAENTGFLQIAGAFV
SERVGLAAQAYSSAQRCLDLTVQWCRDRETFGRPLISRQSVQNTLAEMARRVDVARVYTRHVVERQLSGETNLIAEVCFA
KNTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTALAAKTLGYQG
>Mature_381_residues
SIWDTPERDQLRKTVRAFADREVLPHVDEWERAGELPRELHRKAGAAGLLGAGMPESVGGGGGDGADAVIICEEMHYAGA
PGGVFASLFTSGIATPHMTASGDERLIDTYVRPTLHGELIGSLAITEPGGGSDVGHLTTRAERDGDSYVVNGAKTYITSG
VRADYVVTAVRTGGPGAGGVSLLVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPAANLIGAENTGFLQIAGAFVS
ERVGLAAQAYSSAQRCLDLTVQWCRDRETFGRPLISRQSVQNTLAEMARRVDVARVYTRHVVERQLSGETNLIAEVCFAK
NTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILGIGGGTTEILTALAAKTLGYQG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=38.3597883597884, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=32.8840970350404, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI4557233, Length=367, Percent_Identity=35.9673024523161, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=33.2446808510638, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=33.0666666666667, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=33.0666666666667, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=33.4302325581395, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=30.7486631016043, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI21361497, Length=379, Percent_Identity=26.6490765171504, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4557235, Length=275, Percent_Identity=30.5454545454545, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI76496475, Length=275, Percent_Identity=30.5454545454545, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI4503943, Length=366, Percent_Identity=26.5027322404372, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7669494, Length=354, Percent_Identity=26.5536723163842, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI38505218, Length=391, Percent_Identity=24.2966751918159, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI48976061, Length=404, Percent_Identity=23.2673267326733, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI211971008, Length=404, Percent_Identity=23.2673267326733, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87081958, Length=350, Percent_Identity=30.8571428571429, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786223, Length=348, Percent_Identity=29.0229885057471, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082384, Length=287, Percent_Identity=28.2229965156794, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=385, Percent_Identity=32.7272727272727, Blast_Score=207, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=385, Percent_Identity=34.2857142857143, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=32.3607427055703, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17505929, Length=369, Percent_Identity=31.9783197831978, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17551932, Length=378, Percent_Identity=30.4232804232804, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=31.2, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=30.3763440860215, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17538396, Length=384, Percent_Identity=30.2083333333333, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=28.4931506849315, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=250, Percent_Identity=32.4, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71985184, Length=358, Percent_Identity=27.3743016759777, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71982178, Length=267, Percent_Identity=28.0898876404494, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=366, Percent_Identity=25.9562841530055, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=29.3103448275862, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71985192, Length=288, Percent_Identity=25.3472222222222, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=332, Percent_Identity=23.7951807228916, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=23.5537190082645, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=33.1564986737401, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21356377, Length=361, Percent_Identity=34.3490304709141, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=33.1564986737401, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24646207, Length=359, Percent_Identity=33.1476323119777, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=29.9465240641711, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281363737, Length=277, Percent_Identity=29.2418772563177, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=26.5415549597855, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 40740; Mature: 40609

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIWDTPERDQLRKTVRAFADREVLPHVDEWERAGELPRELHRKAGAAGLLGAGMPESVG
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHCCCCCHHCCCCCCCCC
GGGGDGADAVIICEEMHYAGAPGGVFASLFTSGIATPHMTASGDERLIDTYVRPTLHGEL
CCCCCCCCEEEEEECHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHH
IGSLAITEPGGGSDVGHLTTRAERDGDSYVVNGAKTYITSGVRADYVVTAVRTGGPGAGG
HHHEEEECCCCCCCCCHHHHHHCCCCCCEEECCHHHHHHCCCCCCEEEEEEECCCCCCCC
VSLLVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPAANLIGAENTGFLQIAGAFV
EEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHCCCCCCCEEEEHHHHH
SERVGLAAQAYSSAQRCLDLTVQWCRDRETFGRPLISRQSVQNTLAEMARRVDVARVYTR
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HVVERQLSGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRIL
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCEEEE
GIGGGTTEILTALAAKTLGYQG
EECCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIWDTPERDQLRKTVRAFADREVLPHVDEWERAGELPRELHRKAGAAGLLGAGMPESVG
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHCCCCCHHCCCCCCCCC
GGGGDGADAVIICEEMHYAGAPGGVFASLFTSGIATPHMTASGDERLIDTYVRPTLHGEL
CCCCCCCCEEEEEECHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHH
IGSLAITEPGGGSDVGHLTTRAERDGDSYVVNGAKTYITSGVRADYVVTAVRTGGPGAGG
HHHEEEECCCCCCCCCHHHHHHCCCCCCEEECCHHHHHHCCCCCCEEEEEEECCCCCCCC
VSLLVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPAANLIGAENTGFLQIAGAFV
EEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHCCCCCCCEEEEHHHHH
SERVGLAAQAYSSAQRCLDLTVQWCRDRETFGRPLISRQSVQNTLAEMARRVDVARVYTR
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HVVERQLSGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRIL
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCEEEE
GIGGGTTEILTALAAKTLGYQG
EECCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]