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The map label for this gene is pabB [H]

Identifier: 119870387

GI number: 119870387

Start: 4578772

End: 4580046

Strand: Direct

Name: pabB [H]

Synonym: Mkms_4358

Alternate gene names: 119870387

Gene position: 4578772-4580046 (Clockwise)

Preceding gene: 119870386

Following gene: 119870389

Centisome position: 79.81

GC content: 73.18

Gene sequence:

>1275_bases
GTGCGGATCGAGCGGCTCGGCGACCTCGGCGATGCGCCCACGGTGCTCGCCGCGGTCGCCTCGGCCGGTGCCGCGCTGGG
ACTCCCGCCGCCCGCCGCACTGCTCGGGGACTGGTTCGGGTCCACGGCCGTCATCGCCCCGTCGGTGACGATCGCACCCG
TCGCGCAGATCGACGTGTTCGACGTGCCGCCCGGCGCCGGGAACGCCGTCGGCGGAGGGTGGTTCGGATACCTGTCCTAC
CCGGATCCCGGCGCCGACGGCGCCGGCCCGCGCATCCCCGCGGCGGCGGGCGGCTGGTCGGACTGTGTGCTGCGCCGGGA
CCGCGAGGGCTGCTGGTGGCATGAAAGCCTCAGCGGCACAACGGCTCCCGCCTGGTTGCTCGACGCCGTCAGGTCCCCCG
GGGCGCCGTCGGCCTACGAGATCGGCTGGACGCCACCGGATCGCGACACCCACCGCCGGGGGGTGACCGACTGCCTGGCC
GCGATCGCCGCCGGCGAGGTGTATCAGGCCTGCGTCTGCACACAGTTCACCGGACGGCTCCGCGGATCGCCGCTGGACTT
CTTCGTCGACACCGCCCGGCGCACCACCCCGGCCCGCGCCGCATACCTGGCCGGCGACTGGGGTGCGGTGGCGTCGCTGT
CCCCGGAACTGTTCCTGCGCCGCCGCGGCACGGCGGTGACGTCCAGCCCGATCAAGGGCACGCTGCCGTCCTCGGCGGAT
CCGCTCGAGCTGCGGGCCTCGGTCAAGGACGTGGCGGAGAACATCATGATCGTCGACCTGGTCCGCAACGACCTCGGCCG
GATCGCGCGGACGGGAACGGTGACGGTGCCCGAACTGCTGGCCGTCCGCCCCGCCCCCGGGGTCTGGCATCTGGTGTCGA
CGGTCACCGCGGACGTCCCCGTCGACCTCCCGATGTCCGACGTGCTCGACGCGACGTTCCCGCCGGCGTCGGTCACCGGC
ACCCCGAAGGGCAGAGCGCGCAGCCTGCTGCGGCACTGGGAGCCGAAGCGACGCGGAATCTATTGCGGCACAATCGGTCT
CGCCTCCCCAGCGGCGGGGTGCGAATTGAACGTGGCGATCCGGACGGTGGAGTTCGGCGCCGACGGGTCGGCCGTGCTCG
GCGTCGGCGGCGGCATCACCGCCGACTCCGATCCCGACCGCGAATGGGACGAATGCCTGCACAAGGCCGCATCCATCGTC
GGCCCCTGTTCGCCGGTGCCGAGCGCCGAACTGATCGCGACGACGCACTGGTCGGTCACCGCCGAACAGCCCTAA

Upstream 100 bases:

>100_bases
CGGCCGGATCAGCCACTTCTACGCGATGCGCAACCCCGACAAGCTGGTCGGCGTGGACGTCCCGCGGGAGATCACCCGCA
CGGTCTGAGAAGCTGAGGCG

Downstream 100 bases:

>100_bases
CCGCGCGAGCGCACCACCGCGTCGTAGAGTTCGCGCCGCGACGGGGCCCCCGGATGGGCGGCGATCACCTCGGCGCACGC
ATCCTTCACCCGGGCGCCGG

Product: aminodeoxychorismate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRIERLGDLGDAPTVLAAVASAGAALGLPPPAALLGDWFGSTAVIAPSVTIAPVAQIDVFDVPPGAGNAVGGGWFGYLSY
PDPGADGAGPRIPAAAGGWSDCVLRRDREGCWWHESLSGTTAPAWLLDAVRSPGAPSAYEIGWTPPDRDTHRRGVTDCLA
AIAAGEVYQACVCTQFTGRLRGSPLDFFVDTARRTTPARAAYLAGDWGAVASLSPELFLRRRGTAVTSSPIKGTLPSSAD
PLELRASVKDVAENIMIVDLVRNDLGRIARTGTVTVPELLAVRPAPGVWHLVSTVTADVPVDLPMSDVLDATFPPASVTG
TPKGRARSLLRHWEPKRRGIYCGTIGLASPAAGCELNVAIRTVEFGADGSAVLGVGGGITADSDPDREWDECLHKAASIV
GPCSPVPSAELIATTHWSVTAEQP

Sequences:

>Translated_424_residues
MRIERLGDLGDAPTVLAAVASAGAALGLPPPAALLGDWFGSTAVIAPSVTIAPVAQIDVFDVPPGAGNAVGGGWFGYLSY
PDPGADGAGPRIPAAAGGWSDCVLRRDREGCWWHESLSGTTAPAWLLDAVRSPGAPSAYEIGWTPPDRDTHRRGVTDCLA
AIAAGEVYQACVCTQFTGRLRGSPLDFFVDTARRTTPARAAYLAGDWGAVASLSPELFLRRRGTAVTSSPIKGTLPSSAD
PLELRASVKDVAENIMIVDLVRNDLGRIARTGTVTVPELLAVRPAPGVWHLVSTVTADVPVDLPMSDVLDATFPPASVTG
TPKGRARSLLRHWEPKRRGIYCGTIGLASPAAGCELNVAIRTVEFGADGSAVLGVGGGITADSDPDREWDECLHKAASIV
GPCSPVPSAELIATTHWSVTAEQP
>Mature_424_residues
MRIERLGDLGDAPTVLAAVASAGAALGLPPPAALLGDWFGSTAVIAPSVTIAPVAQIDVFDVPPGAGNAVGGGWFGYLSY
PDPGADGAGPRIPAAAGGWSDCVLRRDREGCWWHESLSGTTAPAWLLDAVRSPGAPSAYEIGWTPPDRDTHRRGVTDCLA
AIAAGEVYQACVCTQFTGRLRGSPLDFFVDTARRTTPARAAYLAGDWGAVASLSPELFLRRRGTAVTSSPIKGTLPSSAD
PLELRASVKDVAENIMIVDLVRNDLGRIARTGTVTVPELLAVRPAPGVWHLVSTVTADVPVDLPMSDVLDATFPPASVTG
TPKGRARSLLRHWEPKRRGIYCGTIGLASPAAGCELNVAIRTVEFGADGSAVLGVGGGITADSDPDREWDECLHKAASIV
GPCSPVPSAELIATTHWSVTAEQP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=285, Percent_Identity=37.5438596491228, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1787518, Length=260, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082077, Length=210, Percent_Identity=31.4285714285714, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=206, Percent_Identity=37.378640776699, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324361, Length=305, Percent_Identity=28.5245901639344, Blast_Score=90, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 44059; Mature: 44059

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIERLGDLGDAPTVLAAVASAGAALGLPPPAALLGDWFGSTAVIAPSVTIAPVAQIDVF
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEECCCCEEEEEEEEEEE
DVPPGAGNAVGGGWFGYLSYPDPGADGAGPRIPAAAGGWSDCVLRRDREGCWWHESLSGT
ECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEECCCCCC
TAPAWLLDAVRSPGAPSAYEIGWTPPDRDTHRRGVTDCLAAIAAGEVYQACVCTQFTGRL
CCHHHHHHHHHCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RGSPLDFFVDTARRTTPARAAYLAGDWGAVASLSPELFLRRRGTAVTSSPIKGTLPSSAD
CCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHCCHHHHHHHCCCEEECCCCCCCCCCCCC
PLELRASVKDVAENIMIVDLVRNDLGRIARTGTVTVPELLAVRPAPGVWHLVSTVTADVP
CHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCHHHHHEECCCCCHHHHHHHHHCCCC
VDLPMSDVLDATFPPASVTGTPKGRARSLLRHWEPKRRGIYCGTIGLASPAAGCELNVAI
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHCCEEEEECCCCCCCCCCEEEEEE
RTVEFGADGSAVLGVGGGITADSDPDREWDECLHKAASIVGPCSPVPSAELIATTHWSVT
EEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEE
AEQP
ECCC
>Mature Secondary Structure
MRIERLGDLGDAPTVLAAVASAGAALGLPPPAALLGDWFGSTAVIAPSVTIAPVAQIDVF
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEECCCCEEEEEEEEEEE
DVPPGAGNAVGGGWFGYLSYPDPGADGAGPRIPAAAGGWSDCVLRRDREGCWWHESLSGT
ECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEECCCCCC
TAPAWLLDAVRSPGAPSAYEIGWTPPDRDTHRRGVTDCLAAIAAGEVYQACVCTQFTGRL
CCHHHHHHHHHCCCCCCCEECCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RGSPLDFFVDTARRTTPARAAYLAGDWGAVASLSPELFLRRRGTAVTSSPIKGTLPSSAD
CCCCHHHHHHHHCCCCCCCEEEEECCCCHHHHCCHHHHHHHCCCEEECCCCCCCCCCCCC
PLELRASVKDVAENIMIVDLVRNDLGRIARTGTVTVPELLAVRPAPGVWHLVSTVTADVP
CHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCHHHHHEECCCCCHHHHHHHHHCCCC
VDLPMSDVLDATFPPASVTGTPKGRARSLLRHWEPKRRGIYCGTIGLASPAAGCELNVAI
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHCCEEEEECCCCCCCCCCEEEEEE
RTVEFGADGSAVLGVGGGITADSDPDREWDECLHKAASIVGPCSPVPSAELIATTHWSVT
EEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEE
AEQP
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]