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The map label for this gene is ectB [H]

Identifier: 119870287

GI number: 119870287

Start: 4483457

End: 4484746

Strand: Direct

Name: ectB [H]

Synonym: Mkms_4257

Alternate gene names: 119870287

Gene position: 4483457-4484746 (Clockwise)

Preceding gene: 119870286

Following gene: 119870288

Centisome position: 78.15

GC content: 65.04

Gene sequence:

>1290_bases
ATGTCAACCCTTGCGGACACGACTGCCGTCGCAGTATCCGACCTACCCGAGGTGTACTCCGCGGTCGAATCCGAGGTACG
TAGCTACTGCCGGGGGTGGCCCACCGTCATGGCCAACGCCTCAGGCTCGTGGGTGACCGACACATCGGGCCGCCGGTATC
TCGACTTCTTCGCCGGCGCAGGCGCATTGAACTATGGACACAACAACCCAGCTCTCAAGAAACCGCTCGTCGAGTATCTG
ACCGGTGACATGATCGTGCACTCGCTCGACATGGCGACGACCGCGAAAAGTGATTTCCTGCAGGCATTTCAGGAGCTGAT
CCTCGAACCGCGCGGTCTCGATTACAAGGTGCAATTCCCCGGCCCCACCGGCGCGAACTCGGTGGAGGCGGCGCTCAAGC
TCGCCAGAAAAGTGACCGGTCGCGAAGCGATCATCAACTTCACCAACGCCTTTCACGGGATGACGCTGGGAGCGCTGTCG
GTGACCGGCAACTCGATGAAACGTGCCGGCGCGGGCATCCCACTGGTGCACACCACGCCGATGCCCTACGACAACTACTT
CGGCGGTGTCACCGAGGACTTCCACTGGTTCGAGCGTGTACTCGACGACTCCGGAAGCGGGTTCAACCGCCCGGCTGCGG
TGATCGTGGAAACCGTGCAGGGTGAAGGCGGGTTGAACGTCGCACGGGCGGAATGGCTTCGGGCGCTCGCGGAGTTGTGC
CGGCGGCGGGAGATCCTGCTGATCGTCGACGACGTGCAGATGGGGTGCGGGCGCACCGGTGCCTTCTTCAGCTTCGAGGA
GGCCGGCATCGTCCCGGACATCGTCACGCTGTCGAAATCCATCAGTGGCTACGGCCTCCCGATGGCACTGACGCTGTTCC
GCAGAGACCTCGACGTGTGGGCCCCCGGTGAGCACAACGGAACCTTCCGCGGCCACAACCCCGCCTTTGTCACCGCCACC
GCCGCGTTGAAGACCTACTGGCGAGACGGCGAGTTCGCGGAGCAGACGTCGGCCAAGGGGGCCATGGTCCGTGATCGGCT
GGAAGCCATCGCCTCCGAGTACGAGGGGGTCAGCGCTCGGGGACGCGGGATGGCGCAGGGCCTGAAGTTCACCGACGCGC
CCGTGGCGGCCACGGTGTGCCGCAAGGCGTTCGAGCGGGGCGTTCTCATGGAGACCAGCGGCCCCTCGGACGAAGTGGTC
AAACTGCTTCCGCCGCTGACCACGTCGACAGCCGACCTCGAGGCGGGGATCTCCGTCCTGGCTGAGTCCGTCGCGGCCGC
ACTGTCGTGA

Upstream 100 bases:

>100_bases
GCACCTCGACGCTGACGAGGCCCACGACGACGAGCCGCTACTCCGTATCGGCCCCCTCACCACAACCCTCGCCGATTGAC
ACCTCTTCTGGAAAGGAACC

Downstream 100 bases:

>100_bases
CCCACATGCACCGAGAGGAAGGATTCACCCGATGATCGTGCGTACCACGCAGGCCATCACCGGTACGGAGCGCGATGTCG
CGGCTAAGGACTGGAGATCC

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSTLADTTAVAVSDLPEVYSAVESEVRSYCRGWPTVMANASGSWVTDTSGRRYLDFFAGAGALNYGHNNPALKKPLVEYL
TGDMIVHSLDMATTAKSDFLQAFQELILEPRGLDYKVQFPGPTGANSVEAALKLARKVTGREAIINFTNAFHGMTLGALS
VTGNSMKRAGAGIPLVHTTPMPYDNYFGGVTEDFHWFERVLDDSGSGFNRPAAVIVETVQGEGGLNVARAEWLRALAELC
RRREILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVTLSKSISGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTAT
AALKTYWRDGEFAEQTSAKGAMVRDRLEAIASEYEGVSARGRGMAQGLKFTDAPVAATVCRKAFERGVLMETSGPSDEVV
KLLPPLTTSTADLEAGISVLAESVAAALS

Sequences:

>Translated_429_residues
MSTLADTTAVAVSDLPEVYSAVESEVRSYCRGWPTVMANASGSWVTDTSGRRYLDFFAGAGALNYGHNNPALKKPLVEYL
TGDMIVHSLDMATTAKSDFLQAFQELILEPRGLDYKVQFPGPTGANSVEAALKLARKVTGREAIINFTNAFHGMTLGALS
VTGNSMKRAGAGIPLVHTTPMPYDNYFGGVTEDFHWFERVLDDSGSGFNRPAAVIVETVQGEGGLNVARAEWLRALAELC
RRREILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVTLSKSISGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTAT
AALKTYWRDGEFAEQTSAKGAMVRDRLEAIASEYEGVSARGRGMAQGLKFTDAPVAATVCRKAFERGVLMETSGPSDEVV
KLLPPLTTSTADLEAGISVLAESVAAALS
>Mature_428_residues
STLADTTAVAVSDLPEVYSAVESEVRSYCRGWPTVMANASGSWVTDTSGRRYLDFFAGAGALNYGHNNPALKKPLVEYLT
GDMIVHSLDMATTAKSDFLQAFQELILEPRGLDYKVQFPGPTGANSVEAALKLARKVTGREAIINFTNAFHGMTLGALSV
TGNSMKRAGAGIPLVHTTPMPYDNYFGGVTEDFHWFERVLDDSGSGFNRPAAVIVETVQGEGGLNVARAEWLRALAELCR
RREILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVTLSKSISGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATA
ALKTYWRDGEFAEQTSAKGAMVRDRLEAIASEYEGVSARGRGMAQGLKFTDAPVAATVCRKAFERGVLMETSGPSDEVVK
LLPPLTTSTADLEAGISVLAESVAAALS

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=403, Percent_Identity=28.0397022332506, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI284507298, Length=313, Percent_Identity=29.073482428115, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI24119277, Length=443, Percent_Identity=24.3792325056433, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=23.696682464455, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226442705, Length=427, Percent_Identity=23.8875878220141, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI226442709, Length=333, Percent_Identity=25.8258258258258, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=30.272952853598, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=30.75, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI145693181, Length=396, Percent_Identity=30.050505050505, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789759, Length=395, Percent_Identity=31.6455696202532, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1788044, Length=403, Percent_Identity=29.5285359801489, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786991, Length=413, Percent_Identity=29.5399515738499, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=403, Percent_Identity=27.0471464019851, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI32564660, Length=425, Percent_Identity=25.8823529411765, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144274, Length=288, Percent_Identity=26.7361111111111, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71992977, Length=473, Percent_Identity=22.4101479915433, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323470, Length=411, Percent_Identity=31.3868613138686, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=29.6954314720812, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321456, Length=431, Percent_Identity=25.0580046403712, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324386, Length=431, Percent_Identity=25.9860788863109, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357415, Length=431, Percent_Identity=27.1461716937355, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28574759, Length=432, Percent_Identity=25.6944444444444, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI161085790, Length=433, Percent_Identity=25.635103926097, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=24.367816091954, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281366494, Length=408, Percent_Identity=23.5294117647059, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667139, Length=408, Percent_Identity=23.5294117647059, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667143, Length=408, Percent_Identity=23.5294117647059, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46055; Mature: 45923

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLADTTAVAVSDLPEVYSAVESEVRSYCRGWPTVMANASGSWVTDTSGRRYLDFFAGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCCCEEHHHHHCC
GALNYGHNNPALKKPLVEYLTGDMIVHSLDMATTAKSDFLQAFQELILEPRGLDYKVQFP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
GPTGANSVEAALKLARKVTGREAIINFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHTTP
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCCEEECCC
MPYDNYFGGVTEDFHWFERVLDDSGSGFNRPAAVIVETVQGEGGLNVARAEWLRALAELC
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
RRREILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVTLSKSISGYGLPMALTLFRRDLDVW
CCCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
APGEHNGTFRGHNPAFVTATAALKTYWRDGEFAEQTSAKGAMVRDRLEAIASEYEGVSAR
CCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GRGMAQGLKFTDAPVAATVCRKAFERGVLMETSGPSDEVVKLLPPLTTSTADLEAGISVL
CCCHHCCCCCCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHH
AESVAAALS
HHHHHHHCC
>Mature Secondary Structure 
STLADTTAVAVSDLPEVYSAVESEVRSYCRGWPTVMANASGSWVTDTSGRRYLDFFAGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCCCCEEHHHHHCC
GALNYGHNNPALKKPLVEYLTGDMIVHSLDMATTAKSDFLQAFQELILEPRGLDYKVQFP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
GPTGANSVEAALKLARKVTGREAIINFTNAFHGMTLGALSVTGNSMKRAGAGIPLVHTTP
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCCEEECCC
MPYDNYFGGVTEDFHWFERVLDDSGSGFNRPAAVIVETVQGEGGLNVARAEWLRALAELC
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
RRREILLIVDDVQMGCGRTGAFFSFEEAGIVPDIVTLSKSISGYGLPMALTLFRRDLDVW
CCCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCC
APGEHNGTFRGHNPAFVTATAALKTYWRDGEFAEQTSAKGAMVRDRLEAIASEYEGVSAR
CCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GRGMAQGLKFTDAPVAATVCRKAFERGVLMETSGPSDEVVKLLPPLTTSTADLEAGISVL
CCCHHCCCCCCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHH
AESVAAALS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA