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The map label for this gene is ectC

Identifier: 119870288

GI number: 119870288

Start: 4484778

End: 4485167

Strand: Direct

Name: ectC

Synonym: Mkms_4258

Alternate gene names: 119870288

Gene position: 4484778-4485167 (Clockwise)

Preceding gene: 119870287

Following gene: 119870289

Centisome position: 78.17

GC content: 64.87

Gene sequence:

>390_bases
ATGATCGTGCGTACCACGCAGGCCATCACCGGTACGGAGCGCGATGTCGCGGCTAAGGACTGGAGATCCAAGCGGATCGT
TCTCGCCGACGACGGCGTCGGCTTCTCGTTCCACGAGACCACCATCAACGCGAACTCGGTCAGCGAGTTCCACTACCGCC
ACCACGTCGAGGCGGTCTGGGTCGTCGAGGGTTCCGGCACGCTGACCGATCACGAGACCGGAGAAGAGTTCCCGCTCCTG
CCGGGCACCATGTACCTGCTCGACGGTCACGAGCGCCACCGTGTCACCTGTCACGAACAGCTCCGCATGCTGTGCGTGTT
CAACCCGCCGGTCACGGGTCAGGAGGTCCACGACGAGTCCGGTGCCTATCCGGCGCCGGTGGCGAGTTGA

Upstream 100 bases:

>100_bases
ACGTCGACAGCCGACCTCGAGGCGGGGATCTCCGTCCTGGCTGAGTCCGTCGCGGCCGCACTGTCGTGACCCACATGCAC
CGAGAGGAAGGATTCACCCG

Downstream 100 bases:

>100_bases
TGGCGGTCGACACGACGCACCGGGTGCGCGACCACTACCCCACCAGACTCGACCAGCCTGCTGAGCCCATCACGCGCGCC
GAACCGACCGTGTGGGGTCG

Product: L-ectoine synthase

Products: NA

Alternate protein names: N-acetyldiaminobutyrate dehydratase

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MIVRTTQAITGTERDVAAKDWRSKRIVLADDGVGFSFHETTINANSVSEFHYRHHVEAVWVVEGSGTLTDHETGEEFPLL
PGTMYLLDGHERHRVTCHEQLRMLCVFNPPVTGQEVHDESGAYPAPVAS

Sequences:

>Translated_129_residues
MIVRTTQAITGTERDVAAKDWRSKRIVLADDGVGFSFHETTINANSVSEFHYRHHVEAVWVVEGSGTLTDHETGEEFPLL
PGTMYLLDGHERHRVTCHEQLRMLCVFNPPVTGQEVHDESGAYPAPVAS
>Mature_129_residues
MIVRTTQAITGTERDVAAKDWRSKRIVLADDGVGFSFHETTINANSVSEFHYRHHVEAVWVVEGSGTLTDHETGEEFPLL
PGTMYLLDGHERHRVTCHEQLRMLCVFNPPVTGQEVHDESGAYPAPVAS

Specific function: Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ectoine synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECTC_MYCSK (A1UKU2)

Other databases:

- EMBL:   CP000518
- RefSeq:   YP_940240.1
- ProteinModelPortal:   A1UKU2
- STRING:   A1UKU2
- EnsemblBacteria:   EBMYCT00000054645
- GeneID:   4612198
- GenomeReviews:   CP000518_GR
- KEGG:   mkm:Mkms_4258
- eggNOG:   NOG08290
- GeneTree:   EBGT00050000016983
- HOGENOM:   HBG294526
- OMA:   DENGVYP
- ProtClustDB:   PRK13290
- BioCyc:   MSP189918:MKMS_4258-MONOMER
- HAMAP:   MF_01255
- InterPro:   IPR011051
- InterPro:   IPR010462
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- ProDom:   PD080544

Pfam domain/function: PF06339 Ectoine_synth; SSF51182 RmlC_like_cupin

EC number: =4.2.1.108

Molecular weight: Translated: 14399; Mature: 14399

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRTTQAITGTERDVAAKDWRSKRIVLADDGVGFSFHETTINANSVSEFHYRHHVEAVW
CEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHEECCEEEE
VVEGSGTLTDHETGEEFPLLPGTMYLLDGHERHRVTCHEQLRMLCVFNPPVTGQEVHDES
EECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEHHCEEEEEEECCCCCCCEECCCC
GAYPAPVAS
CCCCCCCCC
>Mature Secondary Structure
MIVRTTQAITGTERDVAAKDWRSKRIVLADDGVGFSFHETTINANSVSEFHYRHHVEAVW
CEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCHHHHHEECCEEEE
VVEGSGTLTDHETGEEFPLLPGTMYLLDGHERHRVTCHEQLRMLCVFNPPVTGQEVHDES
EECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEHHCEEEEEEECCCCCCCEECCCC
GAYPAPVAS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA