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The map label for this gene is glpX [H]

Identifier: 119870226

GI number: 119870226

Start: 4422251

End: 4423312

Strand: Direct

Name: glpX [H]

Synonym: Mkms_4196

Alternate gene names: 119870226

Gene position: 4422251-4423312 (Clockwise)

Preceding gene: 119870223

Following gene: 119870227

Centisome position: 77.08

GC content: 69.4

Gene sequence:

>1062_bases
ATGCCAGCTGACCCTGATGCTCTTCGCGCAAGCGGCTCATCGCGCCGCAGAGAAGCCCCCGACCGCAACCTCGCCCTCGA
ACTCGTCCGCGTCACCGAGGCCGGCGCCATGGCGGCGGGCCGCTGGGTAGGGCGCGGGGACAAGGAGGGCGGCGACGGCG
CAGCGGTCGACGCCATGCGCGAACTGGTCAACTCGGTGTCGATGCGCGGCGTCGTGGTGATCGGCGAGGGCGAGAAGGAC
AACGCGCCGATGCTCTACAACGGCGAGGAGGTCGGCAACGGCGACGGGCCCGACTGCGACTTCGCCGTCGACCCCATCGA
CGGCACCACGCTGATGAGCAAGGGCATGCCGAACGCGATCTCGGTGCTCGCCGTGGCCGAGCGCGGCGCGATGTTCGACC
CGTCGGCGGTGTTCTACATGAACAAGATCGCCGTCGGTCCGGACGCCGTCGACGCCATCGACATCACCGCGCCGATCGGC
GAGAACGTGCGCGCCGTGGCCAAGGTCAAGGGGCTGTCGGTGCGCGACGTGACGGTCTGCATCCTCGACCGGCCGCGTCA
CGAACAGCTCATCGCCGACGTCCGCGACTCCGGCGCCCGCATCCGGCTGATCTCCGACGGTGACGTCGCGGGCGCGATCT
CGGCGTGCCGGCCGAATTCGGGTACCGACATGCTGGCCGGTATCGGTGGCACCCCCGAGGGCATCATCACCGCCGCCGCC
ATCCGCTGTATGGGCGGCGCCATCCACGCCCAGCTCGCCCCCAAGGACGACGAGGAGCGCCAGAAGGCCATCGACGCCGG
CCACGACATCGACCGCGTGCTCAAGACCGAGGATCTGGTGTCGGGCGAGAACGTGTTCTTCTGCGCGACCGGCGTCACCG
ACGGCGACCTGCTGCAGGGCGTGCGCTACACCGGCGGCGGGTGCACCACCCAGTCGATCGTGATGCGGTCGAAGTCCGGC
ACGGTCCGCATGATCGAGGCCTACCACCGGCTGTCCAAGCTCAACGAGTACTCCGCTGTCGACTTCACCGGCGACAGCAA
CGCCGCCTATCCCCTGCCGTAA

Upstream 100 bases:

>100_bases
ACCACTCCTGCGGGGGCGGTTCCGGCTGGCCGGGGTCGACGGTCATGACAGCCAGTATCCCAGCCTCCCGACGGTGAGCG
GCTTCTGGGACAATCTGCGC

Downstream 100 bases:

>100_bases
CCGATCAGAAGGGCATCCATGACCGCCGACAGCGCTGTCGACCAGAACACCGAGTACCGCATCGAACACGACACCATGGG
CGAGGTCCGGGTGCCCAAGG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MPADPDALRASGSSRRREAPDRNLALELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKD
NAPMLYNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAISVLAVAERGAMFDPSAVFYMNKIAVGPDAVDAIDITAPIG
ENVRAVAKVKGLSVRDVTVCILDRPRHEQLIADVRDSGARIRLISDGDVAGAISACRPNSGTDMLAGIGGTPEGIITAAA
IRCMGGAIHAQLAPKDDEERQKAIDAGHDIDRVLKTEDLVSGENVFFCATGVTDGDLLQGVRYTGGGCTTQSIVMRSKSG
TVRMIEAYHRLSKLNEYSAVDFTGDSNAAYPLP

Sequences:

>Translated_353_residues
MPADPDALRASGSSRRREAPDRNLALELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKD
NAPMLYNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAISVLAVAERGAMFDPSAVFYMNKIAVGPDAVDAIDITAPIG
ENVRAVAKVKGLSVRDVTVCILDRPRHEQLIADVRDSGARIRLISDGDVAGAISACRPNSGTDMLAGIGGTPEGIITAAA
IRCMGGAIHAQLAPKDDEERQKAIDAGHDIDRVLKTEDLVSGENVFFCATGVTDGDLLQGVRYTGGGCTTQSIVMRSKSG
TVRMIEAYHRLSKLNEYSAVDFTGDSNAAYPLP
>Mature_352_residues
PADPDALRASGSSRRREAPDRNLALELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDN
APMLYNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAISVLAVAERGAMFDPSAVFYMNKIAVGPDAVDAIDITAPIGE
NVRAVAKVKGLSVRDVTVCILDRPRHEQLIADVRDSGARIRLISDGDVAGAISACRPNSGTDMLAGIGGTPEGIITAAAI
RCMGGAIHAQLAPKDDEERQKAIDAGHDIDRVLKTEDLVSGENVFFCATGVTDGDLLQGVRYTGGGCTTQSIVMRSKSGT
VRMIEAYHRLSKLNEYSAVDFTGDSNAAYPLP

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=325, Percent_Identity=43.3846153846154, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI1789298, Length=320, Percent_Identity=40.3125, Blast_Score=231, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 36976; Mature: 36845

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPADPDALRASGSSRRREAPDRNLALELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMR
CCCCCHHHHCCCCCHHCCCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCCCCCHHHHHHH
ELVNSVSMRGVVVIGEGEKDNAPMLYNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAI
HHHHHHCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEECCCCCCHHHHCCCCCHH
SVLAVAERGAMFDPSAVFYMNKIAVGPDAVDAIDITAPIGENVRAVAKVKGLSVRDVTVC
EEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCEEHHHHCCCCCCEEEEE
ILDRPRHEQLIADVRDSGARIRLISDGDVAGAISACRPNSGTDMLAGIGGTPEGIITAAA
EECCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHH
IRCMGGAIHAQLAPKDDEERQKAIDAGHDIDRVLKTEDLVSGENVFFCATGVTDGDLLQG
HHHHCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCC
VRYTGGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAVDFTGDSNAAYPLP
CEECCCCCCHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
PADPDALRASGSSRRREAPDRNLALELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMR
CCCCHHHHCCCCCHHCCCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCCCCCHHHHHHH
ELVNSVSMRGVVVIGEGEKDNAPMLYNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAI
HHHHHHCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEECCCCCCHHHHCCCCCHH
SVLAVAERGAMFDPSAVFYMNKIAVGPDAVDAIDITAPIGENVRAVAKVKGLSVRDVTVC
EEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCEEHHHHCCCCCCEEEEE
ILDRPRHEQLIADVRDSGARIRLISDGDVAGAISACRPNSGTDMLAGIGGTPEGIITAAA
EECCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHH
IRCMGGAIHAQLAPKDDEERQKAIDAGHDIDRVLKTEDLVSGENVFFCATGVTDGDLLQG
HHHHCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCC
VRYTGGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAVDFTGDSNAAYPLP
CEECCCCCCHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]