| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
Click here to switch to the map view.
The map label for this gene is rsbU [H]
Identifier: 119870004
GI number: 119870004
Start: 4189064
End: 4191049
Strand: Direct
Name: rsbU [H]
Synonym: Mkms_3974
Alternate gene names: 119870004
Gene position: 4189064-4191049 (Clockwise)
Preceding gene: 119869996
Following gene: 119870005
Centisome position: 73.02
GC content: 70.75
Gene sequence:
>1986_bases GTGGATCCTGATCAGGGGGCGCTGGGAGATCACCGGGTTCGCTCACGAAAACCGGCCGTGGTGTTCGTCGTCGGGTGTCT GTTCGCCGTCCTCGTCGTCGGGTGGCTATCGCTGGTGACCCAGCCGACGGCGCTGGCCAGCACGGCGTGGTGGCCCGTCG CCGGGATCGCGGTCGGGTTGGGCATCCGCTTCCCGCGCCGTCAGGTGTGGGCGCCGGCCGCCGCCGTCGCCGCGATCACC CTTCCGCTCCTGCTCTGGGCGGGACGGCCCGCTGCGCTCGCGACCGCGCTCGCATTCGCCGTCGCCCTCGAGATGGTGAT CGCCACCCTCATCCTCAGGGGGCGCCACGATCGCCTGCCGAGCCTGTCGGAACCGCGCGACCTCGGCCGGTTACTGGTGG CCGTCGCCTCGGCGGCGATCGTCTACGACGTGGTCGGCGCCGGCGCCACCTACCTGCTCGCCGATTCCACCGAGGCGTGG ATCCGGTTCGTCACGTCCGCGCCGAAGCACGCGGCCGGGATGCTGCTGCTGGTCCCGCTGTTCATGCACCTGCCGCGCCG CCCCCGGCCTGCGGGTCCGGTCGAGACCGTCGCGCAGGTCGTGACGACCCTGGGCCTGGTCACCTTCGTGTTCGCGTTCA ACCCCGGAATGCCGCTGTCCTTCCTCCCCTTCATGCCACTGGTGTGGGTGGCGATCCGACTGACGACCCGGGAACTGATC CTGCTGATGCTGGCGATCGCCGTCATCGCCTCGGCCGGCAGCGCGTACGGCACCGGGCCGTTCGCGTTCAACCTCCTCGC ACCGGAGGTGGGCAACCTCGTCCTGCAGGTCTTCGAGCTGTCGATGGTGGTCGTCTTCCTCTCGCTCTCGCTCGCGGTCG GCCACGAGCGGACCACCGCACGGCGCCTCAACGAGAGCGAGGAGTTGTTCCGCCGGATCTTCGAAACGTCGGTGGCCGGG ATGCTGATCGCCACCCGTGCCGCCACGGGATGGAAGGTGTTGCGCGCCAACGACTCCGCGGTGGCCATCATCCCCGGTCT CGCCGACGCGTCGGCCGAGCTCACCGATCTGTTGGGCGAGGAGGCCACCGCCGCGCTCTCGGCGGAAGCCGACGCGCTCA CCGAGGGCAACGCGCGCCTGACGCTGACCACCGGCACCGAGCGGATCCTCAACGTCAGCATCTCCCCGATCAGCGTCGAC GGGGACAGCAGGACCCTCGCGCTGCAGTTCTACGACATCACCGAGGCGATGCGCGCCCGCAGGCTGGAACAGGAGGAACT CGAGCGCGCCGCCGAAGTGCAACGTGCCCTCCTGCCCGGGACGCTCCCACCCACCCCCGGGTGGACTTCCGGTGCGGCTT CGGTGCCGGCCAGACAGGTCGGCGGGGACTTCTACGACATCCGGGTCCAGGTCCCGCACGTGGTCCTCAGCCTCGGCGAC GTCATGGGTAAGGGCATGGGCGCGGGAATGTTGGCCGCCGCGACCAGAGCCGCGCTGCGCGCCACCGACCCCGAGCTCAG TCCATCGGCCGCCGTGAGCCACATGGCCGGGGTCGTCGATCACGACCTGCAACGCACCAGCGCCTTCATCACGCTGACCT ACGTCCTCGTCGACCTCGTCACCGGCGACTTCCGCGTCGCCGACGCCGGGCACGGACTGCACTTCGTCGTCCGGACCGGA TCGGGTCTGGTGGAGCGCACCGCCTCCAGCGATATGCCGGTGGGGCTCGACAGCGGCTGGGGCGAGAAGCGCGGAGCGCT CCAGCCCGGCGACGCGATCCTCCTCGTCAGCGACGGCGTGATGGACCTGTGGGGCGGCTCCGTCGAAGAGCTGTCGGATG CCGTGGCACAGTGCGCCCGGCAGCACGGCACGAGCCCGCAGGCGTTGGTCGACGCCCTGTGCGCGCGGGCGAACGGTGAT CTGGACCGCGATGATGTGACGGCCGTCGTCCTGCGGCGGGAACCGGTGGACGTGGCGGCACGCTGA
Upstream 100 bases:
>100_bases GACGAATTCCGGTGAGTTAACTACGCCAGGACGCGCCCGCACGTCGACCCGGTCGCCCACTCGACCGCATTCGCGTTGAT CAGCGTGTAAAAGTGAGCGG
Downstream 100 bases:
>100_bases CCGCGAACTTCGAACCATCCTGCCGTGAGTTTGCTGAACACCGACACAGTTGCGTTTGTTCGCAAAGATCGGTGCCCACC CGAAAGGGAGGCATTTGCCC
Product: stage II sporulation E family protein
Products: NA
Alternate protein names: Sigma factor sigB regulation protein rsbU [H]
Number of amino acids: Translated: 661; Mature: 661
Protein sequence:
>661_residues MDPDQGALGDHRVRSRKPAVVFVVGCLFAVLVVGWLSLVTQPTALASTAWWPVAGIAVGLGIRFPRRQVWAPAAAVAAIT LPLLLWAGRPAALATALAFAVALEMVIATLILRGRHDRLPSLSEPRDLGRLLVAVASAAIVYDVVGAGATYLLADSTEAW IRFVTSAPKHAAGMLLLVPLFMHLPRRPRPAGPVETVAQVVTTLGLVTFVFAFNPGMPLSFLPFMPLVWVAIRLTTRELI LLMLAIAVIASAGSAYGTGPFAFNLLAPEVGNLVLQVFELSMVVVFLSLSLAVGHERTTARRLNESEELFRRIFETSVAG MLIATRAATGWKVLRANDSAVAIIPGLADASAELTDLLGEEATAALSAEADALTEGNARLTLTTGTERILNVSISPISVD GDSRTLALQFYDITEAMRARRLEQEELERAAEVQRALLPGTLPPTPGWTSGAASVPARQVGGDFYDIRVQVPHVVLSLGD VMGKGMGAGMLAAATRAALRATDPELSPSAAVSHMAGVVDHDLQRTSAFITLTYVLVDLVTGDFRVADAGHGLHFVVRTG SGLVERTASSDMPVGLDSGWGEKRGALQPGDAILLVSDGVMDLWGGSVEELSDAVAQCARQHGTSPQALVDALCARANGD LDRDDVTAVVLRREPVDVAAR
Sequences:
>Translated_661_residues MDPDQGALGDHRVRSRKPAVVFVVGCLFAVLVVGWLSLVTQPTALASTAWWPVAGIAVGLGIRFPRRQVWAPAAAVAAIT LPLLLWAGRPAALATALAFAVALEMVIATLILRGRHDRLPSLSEPRDLGRLLVAVASAAIVYDVVGAGATYLLADSTEAW IRFVTSAPKHAAGMLLLVPLFMHLPRRPRPAGPVETVAQVVTTLGLVTFVFAFNPGMPLSFLPFMPLVWVAIRLTTRELI LLMLAIAVIASAGSAYGTGPFAFNLLAPEVGNLVLQVFELSMVVVFLSLSLAVGHERTTARRLNESEELFRRIFETSVAG MLIATRAATGWKVLRANDSAVAIIPGLADASAELTDLLGEEATAALSAEADALTEGNARLTLTTGTERILNVSISPISVD GDSRTLALQFYDITEAMRARRLEQEELERAAEVQRALLPGTLPPTPGWTSGAASVPARQVGGDFYDIRVQVPHVVLSLGD VMGKGMGAGMLAAATRAALRATDPELSPSAAVSHMAGVVDHDLQRTSAFITLTYVLVDLVTGDFRVADAGHGLHFVVRTG SGLVERTASSDMPVGLDSGWGEKRGALQPGDAILLVSDGVMDLWGGSVEELSDAVAQCARQHGTSPQALVDALCARANGD LDRDDVTAVVLRREPVDVAAR >Mature_661_residues MDPDQGALGDHRVRSRKPAVVFVVGCLFAVLVVGWLSLVTQPTALASTAWWPVAGIAVGLGIRFPRRQVWAPAAAVAAIT LPLLLWAGRPAALATALAFAVALEMVIATLILRGRHDRLPSLSEPRDLGRLLVAVASAAIVYDVVGAGATYLLADSTEAW IRFVTSAPKHAAGMLLLVPLFMHLPRRPRPAGPVETVAQVVTTLGLVTFVFAFNPGMPLSFLPFMPLVWVAIRLTTRELI LLMLAIAVIASAGSAYGTGPFAFNLLAPEVGNLVLQVFELSMVVVFLSLSLAVGHERTTARRLNESEELFRRIFETSVAG MLIATRAATGWKVLRANDSAVAIIPGLADASAELTDLLGEEATAALSAEADALTEGNARLTLTTGTERILNVSISPISVD GDSRTLALQFYDITEAMRARRLEQEELERAAEVQRALLPGTLPPTPGWTSGAASVPARQVGGDFYDIRVQVPHVVLSLGD VMGKGMGAGMLAAATRAALRATDPELSPSAAVSHMAGVVDHDLQRTSAFITLTYVLVDLVTGDFRVADAGHGLHFVVRTG SGLVERTASSDMPVGLDSGWGEKRGALQPGDAILLVSDGVMDLWGGSVEELSDAVAQCARQHGTSPQALVDALCARANGD LDRDDVTAVVLRREPVDVAAR
Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]
COG id: COG2208
COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PP2C-like domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017944 - InterPro: IPR001932 - InterPro: IPR014787 - InterPro: IPR010822 - ProDom: PD685490 [H]
Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]
EC number: =3.1.3.3 [H]
Molecular weight: Translated: 69818; Mature: 69818
Theoretical pI: Translated: 5.50; Mature: 5.50
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDPDQGALGDHRVRSRKPAVVFVVGCLFAVLVVGWLSLVTQPTALASTAWWPVAGIAVGL CCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHH GIRFPRRQVWAPAAAVAAITLPLLLWAGRPAALATALAFAVALEMVIATLILRGRHDRLP CCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC SLSEPRDLGRLLVAVASAAIVYDVVGAGATYLLADSTEAWIRFVTSAPKHAAGMLLLVPL CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHH FMHLPRRPRPAGPVETVAQVVTTLGLVTFVFAFNPGMPLSFLPFMPLVWVAIRLTTRELI HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH LLMLAIAVIASAGSAYGTGPFAFNLLAPEVGNLVLQVFELSMVVVFLSLSLAVGHERTTA HHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH RRLNESEELFRRIFETSVAGMLIATRAATGWKVLRANDSAVAIIPGLADASAELTDLLGE HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHH EATAALSAEADALTEGNARLTLTTGTERILNVSISPISVDGDSRTLALQFYDITEAMRAR HHHHHHHCCCHHHCCCCCEEEEEECCCEEEEEEECEEEECCCCCEEEEEEHHHHHHHHHH RLEQEELERAAEVQRALLPGTLPPTPGWTSGAASVPARQVGGDFYDIRVQVPHVVLSLGD CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEEHHHHHHHHHH VMGKGMGAGMLAAATRAALRATDPELSPSAAVSHMAGVVDHDLQRTSAFITLTYVLVDLV HHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TGDFRVADAGHGLHFVVRTGSGLVERTASSDMPVGLDSGWGEKRGALQPGDAILLVSDGV CCCEEEEECCCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC MDLWGGSVEELSDAVAQCARQHGTSPQALVDALCARANGDLDRDDVTAVVLRREPVDVAA HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC R C >Mature Secondary Structure MDPDQGALGDHRVRSRKPAVVFVVGCLFAVLVVGWLSLVTQPTALASTAWWPVAGIAVGL CCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHH GIRFPRRQVWAPAAAVAAITLPLLLWAGRPAALATALAFAVALEMVIATLILRGRHDRLP CCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC SLSEPRDLGRLLVAVASAAIVYDVVGAGATYLLADSTEAWIRFVTSAPKHAAGMLLLVPL CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHH FMHLPRRPRPAGPVETVAQVVTTLGLVTFVFAFNPGMPLSFLPFMPLVWVAIRLTTRELI HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH LLMLAIAVIASAGSAYGTGPFAFNLLAPEVGNLVLQVFELSMVVVFLSLSLAVGHERTTA HHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH RRLNESEELFRRIFETSVAGMLIATRAATGWKVLRANDSAVAIIPGLADASAELTDLLGE HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHH EATAALSAEADALTEGNARLTLTTGTERILNVSISPISVDGDSRTLALQFYDITEAMRAR HHHHHHHCCCHHHCCCCCEEEEEECCCEEEEEEECEEEECCCCCEEEEEEHHHHHHHHHH RLEQEELERAAEVQRALLPGTLPPTPGWTSGAASVPARQVGGDFYDIRVQVPHVVLSLGD CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEEHHHHHHHHHH VMGKGMGAGMLAAATRAALRATDPELSPSAAVSHMAGVVDHDLQRTSAFITLTYVLVDLV HHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TGDFRVADAGHGLHFVVRTGSGLVERTASSDMPVGLDSGWGEKRGALQPGDAILLVSDGV CCCEEEEECCCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC MDLWGGSVEELSDAVAQCARQHGTSPQALVDALCARANGDLDRDDVTAVVLRREPVDVAA HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC R C
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]