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The map label for this gene is 119869934

Identifier: 119869934

GI number: 119869934

Start: 4110299

End: 4111759

Strand: Direct

Name: 119869934

Synonym: Mkms_3904

Alternate gene names: NA

Gene position: 4110299-4111759 (Clockwise)

Preceding gene: 119869933

Following gene: 119869935

Centisome position: 71.64

GC content: 70.77

Gene sequence:

>1461_bases
GTGCGCGCCAGGTACGCGGCGGGTCTGGCGACCGCATTCTTGCTGACGGCCGCCGAGGTGACCGCGATCGTCGTCACGCT
CGGTGTCGAGCGCGTCGCGGGCGCGGAGGCGCTGCTGACCGCGCGCAACCTGTTCGCGGTGGTGGGTCTCATCGCCGCGG
GAGTGCTGGGCACCACGGTGGGGGGTCTGGCCGCGCTGGCACCGGCGTTCCGGCGGTTGTCCGACGGGCGAGACTCGCCC
GAATCCCGACGTGCCACGACGAACATCACCGCGCGGCTGTCCGCGGCTCTGCTGACCCCGTGGGCCGTGGCGGCCGGTGT
GCTGATCGCCCTCAACCTCCGGGCGGGCGCCGAGCCCCTCCTCGTGATCATCACGGCCGCGATGTTCGGCGCCACCGCCA
CCGTGTGCACCGGTTTCCTGTTCACCCAGCGCACCCTGCGACCGTTGATGGCCGTGCTGACCACCGAAGTCGACCAGGCC
GAGGTGGTACCCGGTGTGCGCGGGCGGCTGGTGCTCATGTGGACCGTGTGCACCGCCCTCCCCGGTGCGGGCATCGTGAC
GCTGGTGGCCCTGCAGCGCCTCGGCCTGCTGGTCGACGATCCCGCGTCGATCGAGCTGCCGGTGCTGGTGCTGGCGCTCG
TCGCCGTGCTGCTCGGCCTGCGGACGTTGATCGTGGTGTCCCGGTCGATCTCGGATCCGGTGCACGACGTGGTCGAGGCG
ATGGGTGAGATCGAGCGTGGCGGGGCCGGACGGCTGGTCGACGTCTACGACCGGTCCGAGATCGGGCATCTGCAGAGCGG
TTTCAACCGCATGGTGATCGGATTGCAAGAGCGCGATCGCCTCCGTGACCTGTTCGGCCGCCACGTCGGACCGGAGGTGG
TGCGCCGCGCCGAGGCGGCGACCGGCGCCGAGGGCGGCGTGCGTTACGCGGCAATCCTTTTCGTCGACCTGGTCGGCTCG
ACCCGGCTGGCCATCGGGCGCGACCCCCAACGGGTCGCCGAGTTGCTCAACGACTTCTTCCAGGTCGTCGTCGCCGCGGT
CGACCACCGGCACGGACTGATCAACAAATTCCAGGGCGATGCCGCCCTCGCCGTGTTCGGCGTACCGCTTGCCATCGACC
GCCCCGCCGACGCAGCCCTGGCGACCGCCCGCACTCTGGCCGCTCAGTTGCGAAGCCGGCCATTGGATTTCGGCATCGGC
GTCTCGGCGGGCCCGGTCTTCGCCGGGAACATCGGCGCGGAGAACCGCTACGAGTACACCGTGATCGGCGACCCGGTCAA
CGAAGCCGCGCGCCTGGCCGACCAGGCCAAGGCCTCCGATGAGCGCGTGCTGTGCTCCGGGGCGGTCTGCGAACGTGCCG
ATCCGCAGGAACGGTCGCACTGGAGCGCGCAGGGTGAGGTGCTGCTGCGCGGCCGGGTGGATCCGACGCCGATCTTCACC
CCGTGTGAGAACACACGTTAG

Upstream 100 bases:

>100_bases
TGGTCACCAAGGCGGGCGCCGGCACCCTGTCCGTCGGCACCACCCCGCTCAACCTCAAAGAGGCCAAACCGCTTCCGGCC
AGCGACTGACCCACCGGTCG

Downstream 100 bases:

>100_bases
TTTCCGGACAAGATCGGGAATGCTCGGTCCCAGCAGTGCTGGGGTCGACGTCGCGATCGAGGAGCAGCCATGGCCACCAT
CGACGGACACCGCCCGCGGG

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MRARYAAGLATAFLLTAAEVTAIVVTLGVERVAGAEALLTARNLFAVVGLIAAGVLGTTVGGLAALAPAFRRLSDGRDSP
ESRRATTNITARLSAALLTPWAVAAGVLIALNLRAGAEPLLVIITAAMFGATATVCTGFLFTQRTLRPLMAVLTTEVDQA
EVVPGVRGRLVLMWTVCTALPGAGIVTLVALQRLGLLVDDPASIELPVLVLALVAVLLGLRTLIVVSRSISDPVHDVVEA
MGEIERGGAGRLVDVYDRSEIGHLQSGFNRMVIGLQERDRLRDLFGRHVGPEVVRRAEAATGAEGGVRYAAILFVDLVGS
TRLAIGRDPQRVAELLNDFFQVVVAAVDHRHGLINKFQGDAALAVFGVPLAIDRPADAALATARTLAAQLRSRPLDFGIG
VSAGPVFAGNIGAENRYEYTVIGDPVNEAARLADQAKASDERVLCSGAVCERADPQERSHWSAQGEVLLRGRVDPTPIFT
PCENTR

Sequences:

>Translated_486_residues
MRARYAAGLATAFLLTAAEVTAIVVTLGVERVAGAEALLTARNLFAVVGLIAAGVLGTTVGGLAALAPAFRRLSDGRDSP
ESRRATTNITARLSAALLTPWAVAAGVLIALNLRAGAEPLLVIITAAMFGATATVCTGFLFTQRTLRPLMAVLTTEVDQA
EVVPGVRGRLVLMWTVCTALPGAGIVTLVALQRLGLLVDDPASIELPVLVLALVAVLLGLRTLIVVSRSISDPVHDVVEA
MGEIERGGAGRLVDVYDRSEIGHLQSGFNRMVIGLQERDRLRDLFGRHVGPEVVRRAEAATGAEGGVRYAAILFVDLVGS
TRLAIGRDPQRVAELLNDFFQVVVAAVDHRHGLINKFQGDAALAVFGVPLAIDRPADAALATARTLAAQLRSRPLDFGIG
VSAGPVFAGNIGAENRYEYTVIGDPVNEAARLADQAKASDERVLCSGAVCERADPQERSHWSAQGEVLLRGRVDPTPIFT
PCENTR
>Mature_486_residues
MRARYAAGLATAFLLTAAEVTAIVVTLGVERVAGAEALLTARNLFAVVGLIAAGVLGTTVGGLAALAPAFRRLSDGRDSP
ESRRATTNITARLSAALLTPWAVAAGVLIALNLRAGAEPLLVIITAAMFGATATVCTGFLFTQRTLRPLMAVLTTEVDQA
EVVPGVRGRLVLMWTVCTALPGAGIVTLVALQRLGLLVDDPASIELPVLVLALVAVLLGLRTLIVVSRSISDPVHDVVEA
MGEIERGGAGRLVDVYDRSEIGHLQSGFNRMVIGLQERDRLRDLFGRHVGPEVVRRAEAATGAEGGVRYAAILFVDLVGS
TRLAIGRDPQRVAELLNDFFQVVVAAVDHRHGLINKFQGDAALAVFGVPLAIDRPADAALATARTLAAQLRSRPLDFGIG
VSAGPVFAGNIGAENRYEYTVIGDPVNEAARLADQAKASDERVLCSGAVCERADPQERSHWSAQGEVLLRGRVDPTPIFT
PCENTR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: NA

Molecular weight: Translated: 51210; Mature: 51210

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARYAAGLATAFLLTAAEVTAIVVTLGVERVAGAEALLTARNLFAVVGLIAAGVLGTTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLAALAPAFRRLSDGRDSPESRRATTNITARLSAALLTPWAVAAGVLIALNLRAGAEPL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHH
LVIITAAMFGATATVCTGFLFTQRTLRPLMAVLTTEVDQAEVVPGVRGRLVLMWTVCTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHC
PGAGIVTLVALQRLGLLVDDPASIELPVLVLALVAVLLGLRTLIVVSRSISDPVHDVVEA
CCCHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MGEIERGGAGRLVDVYDRSEIGHLQSGFNRMVIGLQERDRLRDLFGRHVGPEVVRRAEAA
HHHHCCCCCCCEEEECCCHHHHHHHHCCHHEEEEHHHHHHHHHHHHCCCCHHHHHHHHHH
TGAEGGVRYAAILFVDLVGSTRLAIGRDPQRVAELLNDFFQVVVAAVDHRHGLINKFQGD
CCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
AALAVFGVPLAIDRPADAALATARTLAAQLRSRPLDFGIGVSAGPVFAGNIGAENRYEYT
CEEEEEECCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCEEEE
VIGDPVNEAARLADQAKASDERVLCSGAVCERADPQERSHWSAQGEVLLRGRVDPTPIFT
EECCCHHHHHHHHHHHCCCCCEEEECCCHHCCCCCHHHHCCCCCCCEEEECCCCCCCCCC
PCENTR
CCCCCC
>Mature Secondary Structure
MRARYAAGLATAFLLTAAEVTAIVVTLGVERVAGAEALLTARNLFAVVGLIAAGVLGTTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GGLAALAPAFRRLSDGRDSPESRRATTNITARLSAALLTPWAVAAGVLIALNLRAGAEPL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHH
LVIITAAMFGATATVCTGFLFTQRTLRPLMAVLTTEVDQAEVVPGVRGRLVLMWTVCTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHC
PGAGIVTLVALQRLGLLVDDPASIELPVLVLALVAVLLGLRTLIVVSRSISDPVHDVVEA
CCCHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MGEIERGGAGRLVDVYDRSEIGHLQSGFNRMVIGLQERDRLRDLFGRHVGPEVVRRAEAA
HHHHCCCCCCCEEEECCCHHHHHHHHCCHHEEEEHHHHHHHHHHHHCCCCHHHHHHHHHH
TGAEGGVRYAAILFVDLVGSTRLAIGRDPQRVAELLNDFFQVVVAAVDHRHGLINKFQGD
CCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
AALAVFGVPLAIDRPADAALATARTLAAQLRSRPLDFGIGVSAGPVFAGNIGAENRYEYT
CEEEEEECCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCEEEE
VIGDPVNEAARLADQAKASDERVLCSGAVCERADPQERSHWSAQGEVLLRGRVDPTPIFT
EECCCHHHHHHHHHHHCCCCCEEEECCCHHCCCCCHHHHCCCCCCCEEEECCCCCCCCCC
PCENTR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]