| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
Click here to switch to the map view.
The map label for this gene is ucpA [C]
Identifier: 119869860
GI number: 119869860
Start: 4042729
End: 4043565
Strand: Direct
Name: ucpA [C]
Synonym: Mkms_3829
Alternate gene names: 119869860
Gene position: 4042729-4043565 (Clockwise)
Preceding gene: 119869859
Following gene: 119869861
Centisome position: 70.46
GC content: 66.43
Gene sequence:
>837_bases ATGGCAGGACGGGTAGAAGGCAAAGTCGCATTCATCACGGGTGCGGCCCGCGGACAGGGCCGGGCCCACGCGGTGCGACT GGCGCAGGAGGGCGCCGACATCATCGCCGTCGACATCTGTAAGCAGATCGACAGCGTCCGGATCCCCCTGTCGACCCCCG AGGATCTCGCCGAGACCGCCGATCTGGTGAAGGGACTCAACCGCCGCATCTACACCGCCGAGGTCGACACCCGCGACTTC GAGGCGTTGAAGGCCGCTGTGGACGCCGGTGTGGAGCAGCTGGGCCGGCTCGACATCATCGTCGCCAACGCCGGTATCGG CAACGGCGGGGAGACGCTGGACAAGACCAGCGACGGCGACTGGGAAGACATGATCGACGTCAACCTCGGCGGCGTGTGGA AGACCGTCAAAGCCGGCGTACCGCACATCCTCGCCGGCGGGCGTGGCGGTTCGATCATCCTCACCAGCTCCGTCGGCGGC CTCAAGGCCTATCCGCACACCGGCCACTACGTGGCGGCCAAACACGGTGTGGTGGGCCTGATGCGGACGTTCGCCGTCGA GTTGGGGGCGCAGAACATTCGCGTGAACTCGGTGCATCCGACCAACGTCAACACGCCGCTGTTCATGAACGAAGGCACCA TGAAGCTGTTCCGTCCCGACCTGGAGAACCCGGGCCCCGAGGACATGAAGGTCGTCGGGCAGATGATGCACACGCTGCCG ATCGGCTGGGTCGAGCCGGAGGACATCGCCAACGCGGTGCTGTTCCTCGCCTCCGACGAGGCCCGCTACATCACCGGCGT CACGCTGCCCGTCGACGGCGGCAGCTGCCTCAAGTAA
Upstream 100 bases:
>100_bases GAAACTGCCCGATTCGAGTGCGACGTTGACACAATGGAATGCCGGTGGGAAGGTGCTGAGCAGGTGCACAGCGCATGACG AACGAGGAATCGAGGAACCG
Downstream 100 bases:
>100_bases CCCACCTCCCACCGACCGGGGACCTCGCCACAGGCGAGGTCCCCGGTTCGCGTTCACGGCACGGGGCGCCCATTCGGGCG AAACATGCGCCACCGTCGCG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 278; Mature: 277
Protein sequence:
>278_residues MAGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQIDSVRIPLSTPEDLAETADLVKGLNRRIYTAEVDTRDF EALKAAVDAGVEQLGRLDIIVANAGIGNGGETLDKTSDGDWEDMIDVNLGGVWKTVKAGVPHILAGGRGGSIILTSSVGG LKAYPHTGHYVAAKHGVVGLMRTFAVELGAQNIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPEDMKVVGQMMHTLP IGWVEPEDIANAVLFLASDEARYITGVTLPVDGGSCLK
Sequences:
>Translated_278_residues MAGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQIDSVRIPLSTPEDLAETADLVKGLNRRIYTAEVDTRDF EALKAAVDAGVEQLGRLDIIVANAGIGNGGETLDKTSDGDWEDMIDVNLGGVWKTVKAGVPHILAGGRGGSIILTSSVGG LKAYPHTGHYVAAKHGVVGLMRTFAVELGAQNIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPEDMKVVGQMMHTLP IGWVEPEDIANAVLFLASDEARYITGVTLPVDGGSCLK >Mature_277_residues AGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQIDSVRIPLSTPEDLAETADLVKGLNRRIYTAEVDTRDFE ALKAAVDAGVEQLGRLDIIVANAGIGNGGETLDKTSDGDWEDMIDVNLGGVWKTVKAGVPHILAGGRGGSIILTSSVGGL KAYPHTGHYVAAKHGVVGLMRTFAVELGAQNIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPEDMKVVGQMMHTLPI GWVEPEDIANAVLFLASDEARYITGVTLPVDGGSCLK
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=278, Percent_Identity=34.8920863309352, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI32483357, Length=269, Percent_Identity=32.3420074349442, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI66933014, Length=273, Percent_Identity=28.2051282051282, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI31542939, Length=264, Percent_Identity=31.8181818181818, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI4504505, Length=224, Percent_Identity=29.0178571428571, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI10190704, Length=270, Percent_Identity=30.3703703703704, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI7705925, Length=269, Percent_Identity=30.1115241635688, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI126723750, Length=271, Percent_Identity=29.520295202952, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI19923817, Length=278, Percent_Identity=25.1798561151079, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI224922801, Length=192, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI142976729, Length=236, Percent_Identity=29.6610169491525, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI5031737, Length=279, Percent_Identity=30.1075268817204, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI59889578, Length=205, Percent_Identity=28.2926829268293, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI40254992, Length=271, Percent_Identity=30.6273062730627, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=30.2564102564103, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI40254986, Length=200, Percent_Identity=31.5, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI223718074, Length=203, Percent_Identity=30.5418719211823, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI4758504, Length=216, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI33667109, Length=205, Percent_Identity=31.7073170731707, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=34.7826086956522, Blast_Score=142, Evalue=2e-35, Organism=Escherichia coli, GI1789208, Length=274, Percent_Identity=31.021897810219, Blast_Score=130, Evalue=7e-32, Organism=Escherichia coli, GI1787335, Length=274, Percent_Identity=33.5766423357664, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI87082160, Length=274, Percent_Identity=28.8321167883212, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1788459, Length=271, Percent_Identity=30.6273062730627, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1787905, Length=272, Percent_Identity=27.5735294117647, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1789378, Length=276, Percent_Identity=26.4492753623188, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI2367175, Length=275, Percent_Identity=28.3636363636364, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1790717, Length=269, Percent_Identity=27.1375464684015, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI2367365, Length=275, Percent_Identity=28.7272727272727, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1789057, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1788891, Length=276, Percent_Identity=26.4492753623188, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787820, Length=252, Percent_Identity=26.5873015873016, Blast_Score=65, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17560676, Length=273, Percent_Identity=30.03663003663, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17555706, Length=272, Percent_Identity=32.7205882352941, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17561402, Length=275, Percent_Identity=31.2727272727273, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI25147288, Length=284, Percent_Identity=31.6901408450704, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17562910, Length=287, Percent_Identity=29.2682926829268, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17559104, Length=293, Percent_Identity=31.740614334471, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17531453, Length=293, Percent_Identity=29.3515358361775, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994604, Length=278, Percent_Identity=29.136690647482, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538486, Length=281, Percent_Identity=29.5373665480427, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562904, Length=287, Percent_Identity=30.6620209059233, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI71994600, Length=274, Percent_Identity=28.4671532846715, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17538480, Length=295, Percent_Identity=31.5254237288136, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562906, Length=289, Percent_Identity=28.719723183391, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562908, Length=291, Percent_Identity=29.8969072164948, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560332, Length=286, Percent_Identity=29.020979020979, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17568967, Length=241, Percent_Identity=28.2157676348548, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560150, Length=284, Percent_Identity=28.8732394366197, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI193204405, Length=285, Percent_Identity=30.5263157894737, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562990, Length=283, Percent_Identity=27.208480565371, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17544670, Length=293, Percent_Identity=27.9863481228669, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17551412, Length=296, Percent_Identity=30.0675675675676, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI115534694, Length=275, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI72000259, Length=281, Percent_Identity=28.1138790035587, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193203117, Length=207, Percent_Identity=28.9855072463768, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17563726, Length=283, Percent_Identity=27.5618374558304, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193203115, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17565030, Length=286, Percent_Identity=29.7202797202797, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17560220, Length=290, Percent_Identity=29.3103448275862, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17564282, Length=207, Percent_Identity=27.536231884058, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538182, Length=278, Percent_Identity=25.8992805755396, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17561272, Length=275, Percent_Identity=25.8181818181818, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=270, Percent_Identity=29.2592592592593, Blast_Score=93, Evalue=5e-20, Organism=Saccharomyces cerevisiae, GI6322861, Length=256, Percent_Identity=28.515625, Blast_Score=74, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=207, Percent_Identity=26.5700483091787, Blast_Score=69, Evalue=8e-13, Organism=Drosophila melanogaster, GI24644339, Length=285, Percent_Identity=31.9298245614035, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI23397609, Length=271, Percent_Identity=30.9963099630996, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21355319, Length=273, Percent_Identity=27.8388278388278, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24639444, Length=276, Percent_Identity=29.3478260869565, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI28571526, Length=273, Percent_Identity=28.2051282051282, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI21357041, Length=269, Percent_Identity=29.368029739777, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI24644337, Length=186, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI18859837, Length=221, Percent_Identity=31.6742081447964, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI24643142, Length=275, Percent_Identity=26.1818181818182, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI17737361, Length=214, Percent_Identity=27.5700934579439, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24649181, Length=205, Percent_Identity=30.2439024390244, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI21355631, Length=217, Percent_Identity=27.1889400921659, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI281364892, Length=208, Percent_Identity=27.8846153846154, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI21357673, Length=203, Percent_Identity=25.615763546798, Blast_Score=70, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 29414; Mature: 29283
Theoretical pI: Translated: 5.16; Mature: 5.16
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQIDSVRIPLSTPEDLAETA CCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEHHHHHHHHCEECCCCCHHHHHHHH DLVKGLNRRIYTAEVDTRDFEALKAAVDAGVEQLGRLDIIVANAGIGNGGETLDKTSDGD HHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCC WEDMIDVNLGGVWKTVKAGVPHILAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGL HHHEEEECCCCHHHHHHCCCCEEEECCCCCEEEEEECCCCEECCCCCCCEEEECCCHHHH MRTFAVELGAQNIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPEDMKVVGQMMHTLP HHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCC IGWVEPEDIANAVLFLASDEARYITGVTLPVDGGSCLK CCCCCHHHHCCEEEEEECCCCEEEEEEEEECCCCCCCC >Mature Secondary Structure AGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQIDSVRIPLSTPEDLAETA CCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEHHHHHHHHCEECCCCCHHHHHHHH DLVKGLNRRIYTAEVDTRDFEALKAAVDAGVEQLGRLDIIVANAGIGNGGETLDKTSDGD HHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCC WEDMIDVNLGGVWKTVKAGVPHILAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGL HHHEEEECCCCHHHHHHCCCCEEEECCCCCEEEEEECCCCEECCCCCCCEEEECCCHHHH MRTFAVELGAQNIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPEDMKVVGQMMHTLP HHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCC IGWVEPEDIANAVLFLASDEARYITGVTLPVDGGSCLK CCCCCHHHHCCEEEEEECCCCEEEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA