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The map label for this gene is yqjQ [H]

Identifier: 119869743

GI number: 119869743

Start: 3918074

End: 3918880

Strand: Direct

Name: yqjQ [H]

Synonym: Mkms_3711

Alternate gene names: 119869743

Gene position: 3918074-3918880 (Clockwise)

Preceding gene: 119869741

Following gene: 119869745

Centisome position: 68.29

GC content: 69.89

Gene sequence:

>807_bases
ATGCCAGTACCCGCACCCCGCCCCGATGCCCGCGCGGTCGTGACCGGCGCGTCCCAGAACATCGGCGAAGCGCTGGCCAC
CGAGTTGGCCGCGCGTGGACACCACCTGATCATCACGGCGCGCCGCGAAGAAGTGCTCACCACGTTGGCGGCCCGGCTGA
CCGAGCGCTACGGCGTGACGGTCGAGGTGCGCCCGGTGGACCTGGCCGATCCGGCCGCCCGCACCGCGCTGTGTGACGAG
CTGGCCACCCGCGAGATCTCCATCCTGTGCGCCAACGCCGGGACCGCCACGTTCGGGCCCGTCGCGCGGCTCGATCCCAC
CGACGAGAAGGCGCAGGTCCAGTTGAACGTGCTCGGCGTGCACGATCTGGTGCTCGCCGTGCTGCCCGGGATGGTGGCGC
GGCGGTCCGGCGGCATCCTGATCTCCGGATCGGCGGCCGGGAACTCCCCCATCCCGAACAACGCGACCTACGCGGCGACC
AAGGCGTTCGTCAACACCTTCAGCGAATCGCTGCGCGGTGAACTCAAGGGTGTCGGTGTGCACGTCACGCTGCTCGCGCC
CGGCCCGGTGCGCGAGACCCTGCCCGACGAACACGAGCAGTCGCTGGTGGAGAGGCTCATCCCCGACTTCCTGTGGATCT
CGACCGAGTACACCGCCAAACTCTCCCTCGACGGGCTGGAGAGCAACAAGATGCGGGTGGTGCCGGGGGTGACGTCGAAG
GCCATGTCGGTGGCCAGCGGGTACGCCCCGCGCGCGATTGTCACGCCGATCGTCGGCGCGGTCTACAAGAAGCTCGGCGG
CGACTGA

Upstream 100 bases:

>100_bases
AGGGCGGGGGTTTCGGCGCGTGTTGGGTCACGGTCGCCCACGATATAGACCACGGATGCGAGGTGACCGCGCACGCGGCC
GTCCCGATATAGTCCCGCCC

Downstream 100 bases:

>100_bases
CGACGGCCTACTCGTCTACCCGCCTGCCAGCGCCGGAATAAGGTTCCGGTACGCATATGGGCGCCCCGGCGTGTCGCAAG
TCTGATGTCGGCGAGGGTGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MPVPAPRPDARAVVTGASQNIGEALATELAARGHHLIITARREEVLTTLAARLTERYGVTVEVRPVDLADPAARTALCDE
LATREISILCANAGTATFGPVARLDPTDEKAQVQLNVLGVHDLVLAVLPGMVARRSGGILISGSAAGNSPIPNNATYAAT
KAFVNTFSESLRGELKGVGVHVTLLAPGPVRETLPDEHEQSLVERLIPDFLWISTEYTAKLSLDGLESNKMRVVPGVTSK
AMSVASGYAPRAIVTPIVGAVYKKLGGD

Sequences:

>Translated_268_residues
MPVPAPRPDARAVVTGASQNIGEALATELAARGHHLIITARREEVLTTLAARLTERYGVTVEVRPVDLADPAARTALCDE
LATREISILCANAGTATFGPVARLDPTDEKAQVQLNVLGVHDLVLAVLPGMVARRSGGILISGSAAGNSPIPNNATYAAT
KAFVNTFSESLRGELKGVGVHVTLLAPGPVRETLPDEHEQSLVERLIPDFLWISTEYTAKLSLDGLESNKMRVVPGVTSK
AMSVASGYAPRAIVTPIVGAVYKKLGGD
>Mature_267_residues
PVPAPRPDARAVVTGASQNIGEALATELAARGHHLIITARREEVLTTLAARLTERYGVTVEVRPVDLADPAARTALCDEL
ATREISILCANAGTATFGPVARLDPTDEKAQVQLNVLGVHDLVLAVLPGMVARRSGGILISGSAAGNSPIPNNATYAATK
AFVNTFSESLRGELKGVGVHVTLLAPGPVRETLPDEHEQSLVERLIPDFLWISTEYTAKLSLDGLESNKMRVVPGVTSKA
MSVASGYAPRAIVTPIVGAVYKKLGGD

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=180, Percent_Identity=35, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI226371731, Length=190, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4557649, Length=208, Percent_Identity=29.3269230769231, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=32.8042328042328, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=32.4742268041237, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=29.5336787564767, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI40548397, Length=235, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI214010158, Length=235, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI214010156, Length=235, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI22758144, Length=235, Percent_Identity=27.6595744680851, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI223718074, Length=183, Percent_Identity=30.6010928961749, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=36.4640883977901, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786701, Length=196, Percent_Identity=28.0612244897959, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082100, Length=186, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787335, Length=181, Percent_Identity=32.5966850828729, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25152911, Length=184, Percent_Identity=34.2391304347826, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI212646214, Length=209, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560176, Length=194, Percent_Identity=28.8659793814433, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=34.8258706467662, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319635, Length=215, Percent_Identity=26.9767441860465, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640442, Length=188, Percent_Identity=34.5744680851064, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=35.7894736842105, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=35.7894736842105, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=34.4262295081967, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=34.4262295081967, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24584752, Length=196, Percent_Identity=34.1836734693878, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=31.8181818181818, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24580925, Length=195, Percent_Identity=29.7435897435897, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28156; Mature: 28024

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPAPRPDARAVVTGASQNIGEALATELAARGHHLIITARREEVLTTLAARLTERYGVT
CCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCE
VEVRPVDLADPAARTALCDELATREISILCANAGTATFGPVARLDPTDEKAQVQLNVLGV
EEEEECCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECH
HDLVLAVLPGMVARRSGGILISGSAAGNSPIPNNATYAATKAFVNTFSESLRGELKGVGV
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
HVTLLAPGPVRETLPDEHEQSLVERLIPDFLWISTEYTAKLSLDGLESNKMRVVPGVTSK
EEEEECCCCCHHCCCCHHHHHHHHHHCHHHEEECCCEEEEEEECCCCCCCEEEECCCCHH
AMSVASGYAPRAIVTPIVGAVYKKLGGD
HHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVPAPRPDARAVVTGASQNIGEALATELAARGHHLIITARREEVLTTLAARLTERYGVT
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCE
VEVRPVDLADPAARTALCDELATREISILCANAGTATFGPVARLDPTDEKAQVQLNVLGV
EEEEECCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECH
HDLVLAVLPGMVARRSGGILISGSAAGNSPIPNNATYAATKAFVNTFSESLRGELKGVGV
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
HVTLLAPGPVRETLPDEHEQSLVERLIPDFLWISTEYTAKLSLDGLESNKMRVVPGVTSK
EEEEECCCCCHHCCCCHHHHHHHHHHCHHHEEECCCEEEEEEECCCCCCCEEEECCCCHH
AMSVASGYAPRAIVTPIVGAVYKKLGGD
HHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]