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The map label for this gene is orn

Identifier: 119869745

GI number: 119869745

Start: 3920635

End: 3921282

Strand: Direct

Name: orn

Synonym: Mkms_3713

Alternate gene names: 119869745

Gene position: 3920635-3921282 (Clockwise)

Preceding gene: 119869743

Following gene: 119869749

Centisome position: 68.34

GC content: 66.36

Gene sequence:

>648_bases
GTGCGTGACGAACTGGTGTGGATCGACTGCGAGATGACCGGCCTGGATCTGAGGTCGGATCTGCTCATCGAGATCGCGGT
GCTGGTCACCGATGCCGACCTGAACATCCTCGGCGACGGGCTCGACGTGGTGATCCACGCGCCCGACGAGGCGCTCGACG
CCATGATCCCGGTGGTGACCGAGATGCACACCCGCTCGGGGCTGATCGAGGAGGTGCGTGCCTCCACGGTCGACCTCGCG
ACGGCCGAGGAGATGGTGCTCGACTACATCCGCGGGCACGTCAAACAGGCCAAGACGGCGCCGCTGGCCGGGAACTCGAT
CGCCACCGACCGCGGGTTCATCGCCCGCGACATGGCCAAACTCGACGACTATCTGCACTACCGAATGATCGACGTCAGCT
CGATCAAGGAGTTGTGCCGCCGGTGGTATCCGCGGATCTACTTCGGTCAGCCCGAGAAAGGTCTTGCGCACCGCGCGCTG
GCCGACATCCACGAGTCGATCCGCGAGCTGAAGTACTACCGGCAGACGGCGTTCGTCGCTCCGCCCGGCCCGTCGACCAG
CGATATCGCCGCGATCGCCGCCGAGCTCGGCCCGCCCGGCAAGGACGCGGCGGATACCGATTCGGCCGCAGGGCACACGA
CCGGTTAA

Upstream 100 bases:

>100_bases
TCAGTCGACTCACTGGTCATGGCGCTGACCCTACTGGGGACGGTCCGCAGTGACGGGTGTCGGCGCACATCCGCGGCGGG
GGCGAATACCCTGATTCGCT

Downstream 100 bases:

>100_bases
GATCGACGGGCTGCGCGGCCCGGCGGGTCCGCAGCGATGGTGGCTGTAGTTCAGTTGGTAGAGCACCAGGTTGTGATCCT
GGCTGTCGCGGGTTCGAGTC

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRDELVWIDCEMTGLDLRSDLLIEIAVLVTDADLNILGDGLDVVIHAPDEALDAMIPVVTEMHTRSGLIEEVRASTVDLA
TAEEMVLDYIRGHVKQAKTAPLAGNSIATDRGFIARDMAKLDDYLHYRMIDVSSIKELCRRWYPRIYFGQPEKGLAHRAL
ADIHESIRELKYYRQTAFVAPPGPSTSDIAAIAAELGPPGKDAADTDSAAGHTTG

Sequences:

>Translated_215_residues
MRDELVWIDCEMTGLDLRSDLLIEIAVLVTDADLNILGDGLDVVIHAPDEALDAMIPVVTEMHTRSGLIEEVRASTVDLA
TAEEMVLDYIRGHVKQAKTAPLAGNSIATDRGFIARDMAKLDDYLHYRMIDVSSIKELCRRWYPRIYFGQPEKGLAHRAL
ADIHESIRELKYYRQTAFVAPPGPSTSDIAAIAAELGPPGKDAADTDSAAGHTTG
>Mature_215_residues
MRDELVWIDCEMTGLDLRSDLLIEIAVLVTDADLNILGDGLDVVIHAPDEALDAMIPVVTEMHTRSGLIEEVRASTVDLA
TAEEMVLDYIRGHVKQAKTAPLAGNSIATDRGFIARDMAKLDDYLHYRMIDVSSIKELCRRWYPRIYFGQPEKGLAHRAL
ADIHESIRELKYYRQTAFVAPPGPSTSDIAAIAAELGPPGKDAADTDSAAGHTTG

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=178, Percent_Identity=48.314606741573, Blast_Score=182, Evalue=2e-46,
Organism=Escherichia coli, GI87082382, Length=173, Percent_Identity=47.9768786127168, Blast_Score=158, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17557752, Length=185, Percent_Identity=47.027027027027, Blast_Score=171, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6323088, Length=190, Percent_Identity=41.0526315789474, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355135, Length=175, Percent_Identity=44.5714285714286, Blast_Score=166, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_MYCSJ (A3Q2P5)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001071913.1
- ProteinModelPortal:   A3Q2P5
- SMR:   A3Q2P5
- STRING:   A3Q2P5
- EnsemblBacteria:   EBMYCT00000051887
- GeneID:   4879356
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_3645
- eggNOG:   COG1949
- GeneTree:   EBGT00050000017547
- HOGENOM:   HBG448545
- OMA:   ARRWYPR
- PhylomeDB:   A3Q2P5
- ProtClustDB:   PRK05359
- BioCyc:   MSP164757:MJLS_3645-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 23558; Mature: 23558

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDELVWIDCEMTGLDLRSDLLIEIAVLVTDADLNILGDGLDVVIHAPDEALDAMIPVVT
CCCCEEEEEEEECCCCCHHHHHHEEEEEEECCCCEEECCCEEEEEECCHHHHHHHHHHHH
EMHTRSGLIEEVRASTVDLATAEEMVLDYIRGHVKQAKTAPLAGNSIATDRGFIARDMAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LDDYLHYRMIDVSSIKELCRRWYPRIYFGQPEKGLAHRALADIHESIRELKYYRQTAFVA
HHHHHHHHEECHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEC
PPGPSTSDIAAIAAELGPPGKDAADTDSAAGHTTG
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDELVWIDCEMTGLDLRSDLLIEIAVLVTDADLNILGDGLDVVIHAPDEALDAMIPVVT
CCCCEEEEEEEECCCCCHHHHHHEEEEEEECCCCEEECCCEEEEEECCHHHHHHHHHHHH
EMHTRSGLIEEVRASTVDLATAEEMVLDYIRGHVKQAKTAPLAGNSIATDRGFIARDMAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LDDYLHYRMIDVSSIKELCRRWYPRIYFGQPEKGLAHRALADIHESIRELKYYRQTAFVA
HHHHHHHHEECHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEC
PPGPSTSDIAAIAAELGPPGKDAADTDSAAGHTTG
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA