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The map label for this gene is linC [H]

Identifier: 119869312

GI number: 119869312

Start: 3437905

End: 3439293

Strand: Direct

Name: linC [H]

Synonym: Mkms_3280

Alternate gene names: 119869312

Gene position: 3437905-3439293 (Clockwise)

Preceding gene: 119869311

Following gene: 119869313

Centisome position: 59.92

GC content: 59.47

Gene sequence:

>1389_bases
ATGAGTATTCCCGCGGCAGTGGCCGCCAAAGCCCAGTCTGCCGTGCCTCTGGAGCTGCAAATCCGCGGCGCACACCTCTA
CGACAAGACACGCCGGTGGGTAACCGGAACCAATGGTAAGAAGATCTTCACCGAGACGCCCATTCCTCCGGTCGAGGACG
TTGATATCGCCGACATCGATCTCAGCAACCCGTTCCTCTACCGCCAAGGCCGCTGGAAGTCCTACTTCGAACGCGTGCGC
AACGAGGCGCCGGTGCACTACCAGGCTCACAGTGCGTTCGGCCCGTTCTGGTCGGTGACCCGCCACGCGGACATCATCGC
CGTCGACAAGAACCACGAGGCTTTCTCCGCAGAGCCGTTCATCATCATCGGGAGACCGCCCCGCTTCATGGACATCGCCA
TGTTCATCGCGATGGATCCGCCACAACACGACTTGCAGCGCGCTTCCGTCCAAGGGGTTGTCGCGCCGAAGAACCTGCGC
GAGATGGAGGGGCTGATCCGCTCGCGTGTCCAGGAAGTGCTGGACGATCTACCGGTGGATCAGCCGTTCAATTGGGTGCA
CCACGTCTCCATCGAACTGACAGCGCGCATGCTCGCGACCCTGCTGGACTTCCCGTACGAGCAGCGGCACAAGCTCGTGG
AATGGTCGGACCTCGCCACCTCCATGGAGCAAGCCAATGGTGGTCCTTCCGACAACGACAGAGTGTTTCGTGGCATGGTC
GACATGGCGAAGGGTCTCAGCGCTCTCTGGCATGACAAGGCGGCCCGTACCGCCAACGGGGAGCGACCGGGCTTCGATCT
GATCACGATGCTGCAGGCCAACGAGGACACTAAGGATCTCATCGACCGCCCGATGGAATTCCTCGGCAATTTGGTACTGC
TGATCGTCGGGGGAAACGACACGACTCGCAACTCGATGAGCGGAGGGGTTCTCGCCTTGAACCAGTTCCCCGATCAGTTC
GAGAAGTTGAAGGCGAACCCTGACCTGATTCCCAACATGGTATCCGAGATCATTCGCTGGCAGACCCCGTTGGCGTACAT
GCGCCGAGTCGCGAAAAAAGACATCATGTTGAACGGGCAATTCATCCGCAAGGGCGACAAGGTCGTGATGTGGTACGCCT
CTGGTAACCGCGATGAGCGTGTCTTCGAGCGGGCCGATGAGTTGATCATCGATAGGAGCAACGCCCGCAATCACATCTCG
TTCGGGTTCGGCGTGCACAGGTGCATGGGAAACCGACTTGCTGAGTTGCAGCTTCGAATCCTGTGGGAGGAATTGCTCCC
TCGCTTTGAGAACATCGAGGTGGTCGGCGAACCCGAGTATGTGCAATCGAATTTCGTCAGGGGTATCAGCAAGCTGATGG
TTCGCCTCACTCCCAGGCCAAGTGCGTGA

Upstream 100 bases:

>100_bases
GTCTTGCCAGATGTCCGCCTCCGAGGCATGGGATGGCTTGACGGTCGAGCTACCTGAGTTCCAGCTCTGAAACAACGTCA
TGGATTTGGAGGAAACAATA

Downstream 100 bases:

>100_bases
CTCCCGAACGAGCGGTGATCGTCGGCGCGAGCCACGCCGGCGCGCAGTTGGCAGCTAATCTTCGAAGGGAGGGGTGGTCT
GGGGAGGTCGTGCTCATCGG

Product: cytochrome P450

Products: NA

Alternate protein names: Cytochrome P450 111; Cytochrome P450lin [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSIPAAVAAKAQSAVPLELQIRGAHLYDKTRRWVTGTNGKKIFTETPIPPVEDVDIADIDLSNPFLYRQGRWKSYFERVR
NEAPVHYQAHSAFGPFWSVTRHADIIAVDKNHEAFSAEPFIIIGRPPRFMDIAMFIAMDPPQHDLQRASVQGVVAPKNLR
EMEGLIRSRVQEVLDDLPVDQPFNWVHHVSIELTARMLATLLDFPYEQRHKLVEWSDLATSMEQANGGPSDNDRVFRGMV
DMAKGLSALWHDKAARTANGERPGFDLITMLQANEDTKDLIDRPMEFLGNLVLLIVGGNDTTRNSMSGGVLALNQFPDQF
EKLKANPDLIPNMVSEIIRWQTPLAYMRRVAKKDIMLNGQFIRKGDKVVMWYASGNRDERVFERADELIIDRSNARNHIS
FGFGVHRCMGNRLAELQLRILWEELLPRFENIEVVGEPEYVQSNFVRGISKLMVRLTPRPSA

Sequences:

>Translated_462_residues
MSIPAAVAAKAQSAVPLELQIRGAHLYDKTRRWVTGTNGKKIFTETPIPPVEDVDIADIDLSNPFLYRQGRWKSYFERVR
NEAPVHYQAHSAFGPFWSVTRHADIIAVDKNHEAFSAEPFIIIGRPPRFMDIAMFIAMDPPQHDLQRASVQGVVAPKNLR
EMEGLIRSRVQEVLDDLPVDQPFNWVHHVSIELTARMLATLLDFPYEQRHKLVEWSDLATSMEQANGGPSDNDRVFRGMV
DMAKGLSALWHDKAARTANGERPGFDLITMLQANEDTKDLIDRPMEFLGNLVLLIVGGNDTTRNSMSGGVLALNQFPDQF
EKLKANPDLIPNMVSEIIRWQTPLAYMRRVAKKDIMLNGQFIRKGDKVVMWYASGNRDERVFERADELIIDRSNARNHIS
FGFGVHRCMGNRLAELQLRILWEELLPRFENIEVVGEPEYVQSNFVRGISKLMVRLTPRPSA
>Mature_461_residues
SIPAAVAAKAQSAVPLELQIRGAHLYDKTRRWVTGTNGKKIFTETPIPPVEDVDIADIDLSNPFLYRQGRWKSYFERVRN
EAPVHYQAHSAFGPFWSVTRHADIIAVDKNHEAFSAEPFIIIGRPPRFMDIAMFIAMDPPQHDLQRASVQGVVAPKNLRE
MEGLIRSRVQEVLDDLPVDQPFNWVHHVSIELTARMLATLLDFPYEQRHKLVEWSDLATSMEQANGGPSDNDRVFRGMVD
MAKGLSALWHDKAARTANGERPGFDLITMLQANEDTKDLIDRPMEFLGNLVLLIVGGNDTTRNSMSGGVLALNQFPDQFE
KLKANPDLIPNMVSEIIRWQTPLAYMRRVAKKDIMLNGQFIRKGDKVVMWYASGNRDERVFERADELIIDRSNARNHISF
GFGVHRCMGNRLAELQLRILWEELLPRFENIEVVGEPEYVQSNFVRGISKLMVRLTPRPSA

Specific function: Catalyzes the 8-methyl hydroxylation of linalool [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71982956, Length=228, Percent_Identity=26.7543859649123, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: =1.14.99.28 [H]

Molecular weight: Translated: 52593; Mature: 52462

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPAAVAAKAQSAVPLELQIRGAHLYDKTRRWVTGTNGKKIFTETPIPPVEDVDIADID
CCCCHHHHHHCCCCCCEEEEEECCHHHHHCCCEEECCCCCEEEECCCCCCCCCCCEEEEE
LSNPFLYRQGRWKSYFERVRNEAPVHYQAHSAFGPFWSVTRHADIIAVDKNHEAFSAEPF
CCCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCHHHHHCCCEEEEECCCCCCCCCCCE
IIIGRPPRFMDIAMFIAMDPPQHDLQRASVQGVVAPKNLREMEGLIRSRVQEVLDDLPVD
EEECCCCCHHEEEEEEECCCCHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHCCCC
QPFNWVHHVSIELTARMLATLLDFPYEQRHKLVEWSDLATSMEQANGGPSDNDRVFRGMV
CCCCHHHEEHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
DMAKGLSALWHDKAARTANGERPGFDLITMLQANEDTKDLIDRPMEFLGNLVLLIVGGND
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCC
TTRNSMSGGVLALNQFPDQFEKLKANPDLIPNMVSEIIRWQTPLAYMRRVAKKDIMLNGQ
CCCCCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCC
FIRKGDKVVMWYASGNRDERVFERADELIIDRSNARNHISFGFGVHRCMGNRLAELQLRI
EEECCCEEEEEEECCCCHHHHHHHHHHHEEECCCCCCEEEECHHHHHHHHHHHHHHHHHH
LWEELLPRFENIEVVGEPEYVQSNFVRGISKLMVRLTPRPSA
HHHHHCCHHCCEEEECCCHHHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
SIPAAVAAKAQSAVPLELQIRGAHLYDKTRRWVTGTNGKKIFTETPIPPVEDVDIADID
CCCHHHHHHCCCCCCEEEEEECCHHHHHCCCEEECCCCCEEEECCCCCCCCCCCEEEEE
LSNPFLYRQGRWKSYFERVRNEAPVHYQAHSAFGPFWSVTRHADIIAVDKNHEAFSAEPF
CCCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCHHHHHCCCEEEEECCCCCCCCCCCE
IIIGRPPRFMDIAMFIAMDPPQHDLQRASVQGVVAPKNLREMEGLIRSRVQEVLDDLPVD
EEECCCCCHHEEEEEEECCCCHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHCCCC
QPFNWVHHVSIELTARMLATLLDFPYEQRHKLVEWSDLATSMEQANGGPSDNDRVFRGMV
CCCCHHHEEHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
DMAKGLSALWHDKAARTANGERPGFDLITMLQANEDTKDLIDRPMEFLGNLVLLIVGGND
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCC
TTRNSMSGGVLALNQFPDQFEKLKANPDLIPNMVSEIIRWQTPLAYMRRVAKKDIMLNGQ
CCCCCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCC
FIRKGDKVVMWYASGNRDERVFERADELIIDRSNARNHISFGFGVHRCMGNRLAELQLRI
EEECCCEEEEEEECCCCHHHHHHHHHHHEEECCCCCCEEEECHHHHHHHHHHHHHHHHHH
LWEELLPRFENIEVVGEPEYVQSNFVRGISKLMVRLTPRPSA
HHHHHCCHHCCEEEECCCHHHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8376348; 2295633; 3813557; 2578028; 1610873; 12237225 [H]