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The map label for this gene is ycbL [H]

Identifier: 119869065

GI number: 119869065

Start: 3176268

End: 3176945

Strand: Direct

Name: ycbL [H]

Synonym: Mkms_3033

Alternate gene names: 119869065

Gene position: 3176268-3176945 (Clockwise)

Preceding gene: 119869063

Following gene: 119869066

Centisome position: 55.36

GC content: 67.85

Gene sequence:

>678_bases
ATGACAGTCGTCGACGACAACTACACCGGCCATGTCGAACCCCGGACCGCGGCCAGGCGCACTCTTCCCGGCGCGACGAT
CGTCAAGGTCTCCGTGGGCCCCATGGACAACAACGCGTACCTGGTGACCTGTTCCCGAACCGGCGAGACCCTACTCATCG
ACGCAGCCAATGATGCGGACGTCCTGCTCGACCTCGTCCGGGAACTGGCACCGACGGTGACACTGATCCTGACCAGCCAC
CAGCACTTCGACCACTGGCAGGCGCTGGAGGCCCTGGTCGAGGCAACCGGGGCACCCACGGCCGCCCACGAACTCGACGC
CGAACCGCTGCCGGTCACCCCGGACCGCTACCTCGCCGGTGGGGACACGCTCGGGATCGGCGAGCTCACCTTCGACGTGA
TCCACCTCCGCGGGCACACCCCAGGTTCGATCGCGTTGGCGCTGCACGGTCCGGCCGCCGGCGACGCGGTGCACCTGTTC
ACCGGCGACTGCCTGTTCCCCGGCGGAGTGGGCAAGACGTGGCAGGAGGGTGATTTCGAGAAACTTCTGACCGACGTCAC
CACCCGGGTGTTCGACGTCTATCCCGACTCGACCGTTGTCTACCCGGGGCACGGCGACGACACCACCTTGGGCGCGGAAC
GGCCGCACCTCGGCGAGTGGCGCGATCGTGGCTGGTAG

Upstream 100 bases:

>100_bases
GCGGTCAGCCAACTCGGTCCTCTCCCAGGCTTCAGACATGCTCCACGCACTTTGATCCATGCTAGGTGTCGCCACCGACA
AGCCCGTTACCGTGGCTCTC

Downstream 100 bases:

>100_bases
ACCGGTTCCGGTCACACCCGGTCCGGGTCAGGAGTCGGTGTGGGACTACCCGCGCCCGCCCCGGCTCGAGGCGTTCCGCG
GATCGATCACCGTGGACTTC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTVVDDNYTGHVEPRTAARRTLPGATIVKVSVGPMDNNAYLVTCSRTGETLLIDAANDADVLLDLVRELAPTVTLILTSH
QHFDHWQALEALVEATGAPTAAHELDAEPLPVTPDRYLAGGDTLGIGELTFDVIHLRGHTPGSIALALHGPAAGDAVHLF
TGDCLFPGGVGKTWQEGDFEKLLTDVTTRVFDVYPDSTVVYPGHGDDTTLGAERPHLGEWRDRGW

Sequences:

>Translated_225_residues
MTVVDDNYTGHVEPRTAARRTLPGATIVKVSVGPMDNNAYLVTCSRTGETLLIDAANDADVLLDLVRELAPTVTLILTSH
QHFDHWQALEALVEATGAPTAAHELDAEPLPVTPDRYLAGGDTLGIGELTFDVIHLRGHTPGSIALALHGPAAGDAVHLF
TGDCLFPGGVGKTWQEGDFEKLLTDVTTRVFDVYPDSTVVYPGHGDDTTLGAERPHLGEWRDRGW
>Mature_224_residues
TVVDDNYTGHVEPRTAARRTLPGATIVKVSVGPMDNNAYLVTCSRTGETLLIDAANDADVLLDLVRELAPTVTLILTSHQ
HFDHWQALEALVEATGAPTAAHELDAEPLPVTPDRYLAGGDTLGIGELTFDVIHLRGHTPGSIALALHGPAAGDAVHLFT
GDCLFPGGVGKTWQEGDFEKLLTDVTTRVFDVYPDSTVVYPGHGDDTTLGAERPHLGEWRDRGW

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Escherichia coli, GI1787158, Length=205, Percent_Identity=31.7073170731707, Blast_Score=97, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17538952, Length=193, Percent_Identity=28.4974093264249, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667703, Length=177, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21356335, Length=177, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24667711, Length=177, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 24151; Mature: 24020

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVDDNYTGHVEPRTAARRTLPGATIVKVSVGPMDNNAYLVTCSRTGETLLIDAANDAD
CEEECCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEECCCCHH
VLLDLVRELAPTVTLILTSHQHFDHWQALEALVEATGAPTAAHELDAEPLPVTPDRYLAG
HHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCEECC
GDTLGIGELTFDVIHLRGHTPGSIALALHGPAAGDAVHLFTGDCLFPGGVGKTWQEGDFE
CCCEEECCEEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCEECCCCCCCCCCCCCHH
KLLTDVTTRVFDVYPDSTVVYPGHGDDTTLGAERPHLGEWRDRGW
HHHHHHHHHHEEECCCCEEEECCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
TVVDDNYTGHVEPRTAARRTLPGATIVKVSVGPMDNNAYLVTCSRTGETLLIDAANDAD
EEECCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEECCCCHH
VLLDLVRELAPTVTLILTSHQHFDHWQALEALVEATGAPTAAHELDAEPLPVTPDRYLAG
HHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCEECC
GDTLGIGELTFDVIHLRGHTPGSIALALHGPAAGDAVHLFTGDCLFPGGVGKTWQEGDFE
CCCEEECCEEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCEECCCCCCCCCCCCCHH
KLLTDVTTRVFDVYPDSTVVYPGHGDDTTLGAERPHLGEWRDRGW
HHHHHHHHHHEEECCCCEEEECCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]