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The map label for this gene is 119869063

Identifier: 119869063

GI number: 119869063

Start: 3171814

End: 3173295

Strand: Direct

Name: 119869063

Synonym: Mkms_3031

Alternate gene names: NA

Gene position: 3171814-3173295 (Clockwise)

Preceding gene: 119869062

Following gene: 119869065

Centisome position: 55.28

GC content: 66.94

Gene sequence:

>1482_bases
GTGAAGATCGCGATCATCGGCAGCGGGTTCTCCGGCCTCGGCGCCGCGATCCGGCTGCAGGAGGCAGGCCACCGCGACTT
CGTCGTCCTCGAACGCGGCCCCGACGTCGGCGGTACCTGGCGCGACAACACCTACCCGGGCGCGGCGTGTGACGTGCCGT
CACATCTGTACTCGTATTCCTTTGCGCTGAACCCGGATTGGACTCGCTCGTTCTCCACCCAACCCGAGATCGAGGACTAT
CTGCGCAAGGTCGCGCAGCGCTATGACGTCCTCGACCGGCACCGCTTCGGGTGCACCGTGAGCCGCGCCGCGTGGAATCC
CACCCAGTCGCAGTGGGAGCTGTCGACCGACTCCGGTCCCGTCACCGCCGATGTCCTGATCACCGCGTTCGGGTCACTGG
CCGAACCGTCACTGCCGGGCATCCCGGGCATCGAATCGTTCACTGCGGCCGGGGGCGAGATGTTCCACTCCGCGCGGTGG
AACCACGACGCGGACCTGACGGGGAAACGGGTCGCCGTCATCGGCACCGGCGCATCGGCCATCCAGATCGTGCCCGAGAT
CGCCGATCGGGTCGCACACCTCGACGTGTACCAGCGCACGGCGCCCTGGCTGCTGCCGCGGTTCGACCGGCCGTTCACCC
GCGCCGAGAAGTGGGCGTTCCGCAACGTGCCGGGCTTTCTCCGCCTGGCGCGCGCGGGCATCTACACCAGCCGCGAAGTC
CAGGTCGTCGGCCTCGCGAAGAACCCGAACCTGATGAAGGGGTTCGAGTTGCTCTCGCGGGCGAAGATCCGCACCGAGAT
CAAAGACCCCGAGTTGCGGCGCAAGGTCACGCCGAACTTCCGGATCGGCTGCAAGCGGATGCTGATCTCCAACGACTGGT
ATCCGACGTTGGACCGGGGCCACGTCGACCTCATCACCGACGGCATCCACGAGATCGACGGCAATCGCATCATCGCGACC
GACGGCACCGCGCGCGAGGTCGACGCCCTCGTCGTCGCGACGGGATTCCACGTCACCGACTCACCGATGTTCGACACGGT
GTGCGGCGCCGACGGCGCCAGCCTGACCCAGCGGTTCGCCGACAAGGGCATGCGGGCTTACAAGGGCACCACGATCGCCG
GGTACCCGAACATGTTCGTGCTCGTCGGACCGAACACCGGGCTGGGCCACAGTTCGATGGTGTACATGATCGAGTCGCAG
CTCAACTACGTCGTCGACGCGGTCTCGACGATGCGGGAGGAGGGTCTGCGCACGGTCGAGGTGAAACAGGACGCGCTCGA
CGCGTACAACGAACGGCTGCAGCAGGCGCTGAGCGGATCGGTGTGGATGACCGGCAAGTGTGCGAGCTGGTACCTCGACG
CGCACGGCAACAACACCACCCTGTGGCCGGACTTCACGTTCCGGTTCCGCAATCAGACCCGGCGCTTCGACCTCGACGCC
TACGAGGTGACGCGCGCCGAGGAGTCGGTGCTCACGCGCTGA

Upstream 100 bases:

>100_bases
GGGACGCGGGTGAGCCCACGATTCCCGTCGCCGCTCATGAAAGCGTGATTGGAACCGGGAGCGGTTGGCTAACCTACGGC
CACCGACGGAAGGGGTTGCG

Downstream 100 bases:

>100_bases
CCTTGCGCCGCTTCCGGGTCGGCGCGGGTACGTCGAGCATCTCGGCGAGGAAGTCTCCGGTGTAGCTGTCGGTGTTGGCC
GCGACGTCCTCAGGCGTGCC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MKIAIIGSGFSGLGAAIRLQEAGHRDFVVLERGPDVGGTWRDNTYPGAACDVPSHLYSYSFALNPDWTRSFSTQPEIEDY
LRKVAQRYDVLDRHRFGCTVSRAAWNPTQSQWELSTDSGPVTADVLITAFGSLAEPSLPGIPGIESFTAAGGEMFHSARW
NHDADLTGKRVAVIGTGASAIQIVPEIADRVAHLDVYQRTAPWLLPRFDRPFTRAEKWAFRNVPGFLRLARAGIYTSREV
QVVGLAKNPNLMKGFELLSRAKIRTEIKDPELRRKVTPNFRIGCKRMLISNDWYPTLDRGHVDLITDGIHEIDGNRIIAT
DGTAREVDALVVATGFHVTDSPMFDTVCGADGASLTQRFADKGMRAYKGTTIAGYPNMFVLVGPNTGLGHSSMVYMIESQ
LNYVVDAVSTMREEGLRTVEVKQDALDAYNERLQQALSGSVWMTGKCASWYLDAHGNNTTLWPDFTFRFRNQTRRFDLDA
YEVTRAEESVLTR

Sequences:

>Translated_493_residues
MKIAIIGSGFSGLGAAIRLQEAGHRDFVVLERGPDVGGTWRDNTYPGAACDVPSHLYSYSFALNPDWTRSFSTQPEIEDY
LRKVAQRYDVLDRHRFGCTVSRAAWNPTQSQWELSTDSGPVTADVLITAFGSLAEPSLPGIPGIESFTAAGGEMFHSARW
NHDADLTGKRVAVIGTGASAIQIVPEIADRVAHLDVYQRTAPWLLPRFDRPFTRAEKWAFRNVPGFLRLARAGIYTSREV
QVVGLAKNPNLMKGFELLSRAKIRTEIKDPELRRKVTPNFRIGCKRMLISNDWYPTLDRGHVDLITDGIHEIDGNRIIAT
DGTAREVDALVVATGFHVTDSPMFDTVCGADGASLTQRFADKGMRAYKGTTIAGYPNMFVLVGPNTGLGHSSMVYMIESQ
LNYVVDAVSTMREEGLRTVEVKQDALDAYNERLQQALSGSVWMTGKCASWYLDAHGNNTTLWPDFTFRFRNQTRRFDLDA
YEVTRAEESVLTR
>Mature_493_residues
MKIAIIGSGFSGLGAAIRLQEAGHRDFVVLERGPDVGGTWRDNTYPGAACDVPSHLYSYSFALNPDWTRSFSTQPEIEDY
LRKVAQRYDVLDRHRFGCTVSRAAWNPTQSQWELSTDSGPVTADVLITAFGSLAEPSLPGIPGIESFTAAGGEMFHSARW
NHDADLTGKRVAVIGTGASAIQIVPEIADRVAHLDVYQRTAPWLLPRFDRPFTRAEKWAFRNVPGFLRLARAGIYTSREV
QVVGLAKNPNLMKGFELLSRAKIRTEIKDPELRRKVTPNFRIGCKRMLISNDWYPTLDRGHVDLITDGIHEIDGNRIIAT
DGTAREVDALVVATGFHVTDSPMFDTVCGADGASLTQRFADKGMRAYKGTTIAGYPNMFVLVGPNTGLGHSSMVYMIESQ
LNYVVDAVSTMREEGLRTVEVKQDALDAYNERLQQALSGSVWMTGKCASWYLDAHGNNTTLWPDFTFRFRNQTRRFDLDA
YEVTRAEESVLTR

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503759, Length=225, Percent_Identity=28.4444444444444, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4503757, Length=361, Percent_Identity=24.0997229916898, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI221316678, Length=224, Percent_Identity=30.3571428571429, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI221316674, Length=224, Percent_Identity=30.3571428571429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI221316672, Length=224, Percent_Identity=30.3571428571429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503755, Length=365, Percent_Identity=24.9315068493151, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI50541965, Length=224, Percent_Identity=25.8928571428571, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI50541961, Length=224, Percent_Identity=25.8928571428571, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25145785, Length=219, Percent_Identity=26.4840182648402, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921694, Length=207, Percent_Identity=28.0193236714976, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 54857; Mature: 54857

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIIGSGFSGLGAAIRLQEAGHRDFVVLERGPDVGGTWRDNTYPGAACDVPSHLYSYS
CEEEEEECCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHEEE
FALNPDWTRSFSTQPEIEDYLRKVAQRYDVLDRHRFGCTVSRAAWNPTQSQWELSTDSGP
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEECCCCC
VTADVLITAFGSLAEPSLPGIPGIESFTAAGGEMFHSARWNHDADLTGKRVAVIGTGASA
CHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHCCCCCCCCCCCCEEEEEECCCHH
IQIVPEIADRVAHLDVYQRTAPWLLPRFDRPFTRAEKWAFRNVPGFLRLARAGIYTSREV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCEE
QVVGLAKNPNLMKGFELLSRAKIRTEIKDPELRRKVTPNFRIGCKRMLISNDWYPTLDRG
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
HVDLITDGIHEIDGNRIIATDGTAREVDALVVATGFHVTDSPMFDTVCGADGASLTQRFA
CEEEEECCHHHCCCCEEEECCCCCHHCEEEEEEECCEECCCCCHHHHCCCCCHHHHHHHH
DKGMRAYKGTTIAGYPNMFVLVGPNTGLGHSSMVYMIESQLNYVVDAVSTMREEGLRTVE
HCCCHHHCCCEEECCCCEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEE
VKQDALDAYNERLQQALSGSVWMTGKCASWYLDAHGNNTTLWPDFTFRFRNQTRRFDLDA
HHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEECCCEEEEECCCCCEECCCH
YEVTRAEESVLTR
HHHHHHHHHHCCC
>Mature Secondary Structure
MKIAIIGSGFSGLGAAIRLQEAGHRDFVVLERGPDVGGTWRDNTYPGAACDVPSHLYSYS
CEEEEEECCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHEEE
FALNPDWTRSFSTQPEIEDYLRKVAQRYDVLDRHRFGCTVSRAAWNPTQSQWELSTDSGP
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEECCCCC
VTADVLITAFGSLAEPSLPGIPGIESFTAAGGEMFHSARWNHDADLTGKRVAVIGTGASA
CHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHCCCCCCCCCCCCEEEEEECCCHH
IQIVPEIADRVAHLDVYQRTAPWLLPRFDRPFTRAEKWAFRNVPGFLRLARAGIYTSREV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCEE
QVVGLAKNPNLMKGFELLSRAKIRTEIKDPELRRKVTPNFRIGCKRMLISNDWYPTLDRG
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCEEEEECCCCCCCCCCC
HVDLITDGIHEIDGNRIIATDGTAREVDALVVATGFHVTDSPMFDTVCGADGASLTQRFA
CEEEEECCHHHCCCCEEEECCCCCHHCEEEEEEECCEECCCCCHHHHCCCCCHHHHHHHH
DKGMRAYKGTTIAGYPNMFVLVGPNTGLGHSSMVYMIESQLNYVVDAVSTMREEGLRTVE
HCCCHHHCCCEEECCCCEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEE
VKQDALDAYNERLQQALSGSVWMTGKCASWYLDAHGNNTTLWPDFTFRFRNQTRRFDLDA
HHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEECCCEEEEECCCCCEECCCH
YEVTRAEESVLTR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]