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The map label for this gene is baeS [H]

Identifier: 119868982

GI number: 119868982

Start: 3083915

End: 3085054

Strand: Direct

Name: baeS [H]

Synonym: Mkms_2950

Alternate gene names: 119868982

Gene position: 3083915-3085054 (Clockwise)

Preceding gene: 119868981

Following gene: 119868998

Centisome position: 53.75

GC content: 70.18

Gene sequence:

>1140_bases
ATGACGGCCGGCATCGGCGCGCGACTGTTCGCAGCGCAGGCGATCGTGCTCACCGTCGGTGCGGCCACCACGTCGATGGC
GGCCGCGATCGTCGGACCACCCCTCTTCCGCGACCACCTCCATCAGGCGGGCGTACCGCCGAACTCGCTCGAGGAGATGC
ACGCCGAGGAAGCGTACGGGTACGCCACGGCCATCTCCATCACCGGCGCACTCGCGGTCTCGGTGCTGGCCGCACTGGCC
GTCAGCTGGTACCTCAGCCGCCGGCTGCAGCGCTCGATCACCGAAGTCGCCTCGGCGGCAACCGCGGTCGCCGACGGCCG
GTACGACATCCGGGTCTCGCCGCCCCATCTCGGTGAGGACTTCGACGCGCTCGCCCACGCGTTCAACCAGATGGCGTCGC
AACTGCAGTCGGTCGAGGTGACTCGTCGCCGACTGTTCAGCGACCTCGCCCACGAGATCCGCACCCCGCTCGCGGTGCTC
GAGGCGTACTTCGAGGCGATCGAGGACGGGGTCCGCAGCCTCACCCCCGAAACCGCCGCGATGCTGCGTGACCAGACTGG
ACGACTGGTCCGGTTCGCAGGCGATCTCGGCGCGCTCGCCCGCGCCGAGGAGAGCTCCGCATCGATGGAGCTCGAGCCGA
TCGACATCCACTCGCTGGTGCAGCGTTGCGCCGCGGCGGCACAGTCGGGCTACTCCCGTAAGGGTGTGGAATTGTGCACG
GCAGTGGACGTCGACCTGCCACCGCTGTGGGGAGACGAGCAGCGCATGAGCCAGGTACTGGCGAATCTGCTCGACAATGC
TCTGCGCCACACGCCCTCCGGCGGACGGGTCGAGATCAGCGCCAGGCGTGACGGGCACCGGGTGTTGATTCGCGTGTCCG
ACAACGGTGAAGGGATCGCCGCCGAGCACCTGCCGCACGTGTTCGAGCGGTTCTACCGGGCGGACTCCGCCCGGGCGCGC
CAGAACGGCGGCGCCGGAATCGGATTGGCGATCGCCAAGGCGGTGGTCGAGGCCCACGGCGGCACCATCGCCGCCGACAG
CGCCGGCGCCGGGAGGGGGACCGTCTTCACCGTCACGGTGCCCGTTCGAGCATCCGCACCTGACCTCGCGCGGCGGCCCC
CGCCGACACCGGTTGCTTGA

Upstream 100 bases:

>100_bases
TCCACATCGGCCACCTGCGGCGCAAGCTCGGAGACGACGCCGCTAACCCCCGGTTCATCATGACCGTGCGGGGTGTGGGC
TACCGGATGGGAAGTTCCCG

Downstream 100 bases:

>100_bases
TCTTGTACAGCGGCGGGTAACCGTGCGCCAACGATGAAGGGGCGGTGGCGTCATGGGGACGGGTTGGTTTGCCGAGAAGG
CTTGTGTGGCTGTGTGTAGG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MTAGIGARLFAAQAIVLTVGAATTSMAAAIVGPPLFRDHLHQAGVPPNSLEEMHAEEAYGYATAISITGALAVSVLAALA
VSWYLSRRLQRSITEVASAATAVADGRYDIRVSPPHLGEDFDALAHAFNQMASQLQSVEVTRRRLFSDLAHEIRTPLAVL
EAYFEAIEDGVRSLTPETAAMLRDQTGRLVRFAGDLGALARAEESSASMELEPIDIHSLVQRCAAAAQSGYSRKGVELCT
AVDVDLPPLWGDEQRMSQVLANLLDNALRHTPSGGRVEISARRDGHRVLIRVSDNGEGIAAEHLPHVFERFYRADSARAR
QNGGAGIGLAIAKAVVEAHGGTIAADSAGAGRGTVFTVTVPVRASAPDLARRPPPTPVA

Sequences:

>Translated_379_residues
MTAGIGARLFAAQAIVLTVGAATTSMAAAIVGPPLFRDHLHQAGVPPNSLEEMHAEEAYGYATAISITGALAVSVLAALA
VSWYLSRRLQRSITEVASAATAVADGRYDIRVSPPHLGEDFDALAHAFNQMASQLQSVEVTRRRLFSDLAHEIRTPLAVL
EAYFEAIEDGVRSLTPETAAMLRDQTGRLVRFAGDLGALARAEESSASMELEPIDIHSLVQRCAAAAQSGYSRKGVELCT
AVDVDLPPLWGDEQRMSQVLANLLDNALRHTPSGGRVEISARRDGHRVLIRVSDNGEGIAAEHLPHVFERFYRADSARAR
QNGGAGIGLAIAKAVVEAHGGTIAADSAGAGRGTVFTVTVPVRASAPDLARRPPPTPVA
>Mature_378_residues
TAGIGARLFAAQAIVLTVGAATTSMAAAIVGPPLFRDHLHQAGVPPNSLEEMHAEEAYGYATAISITGALAVSVLAALAV
SWYLSRRLQRSITEVASAATAVADGRYDIRVSPPHLGEDFDALAHAFNQMASQLQSVEVTRRRLFSDLAHEIRTPLAVLE
AYFEAIEDGVRSLTPETAAMLRDQTGRLVRFAGDLGALARAEESSASMELEPIDIHSLVQRCAAAAQSGYSRKGVELCTA
VDVDLPPLWGDEQRMSQVLANLLDNALRHTPSGGRVEISARRDGHRVLIRVSDNGEGIAAEHLPHVFERFYRADSARARQ
NGGAGIGLAIAKAVVEAHGGTIAADSAGAGRGTVFTVTVPVRASAPDLARRPPPTPVA

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=270, Percent_Identity=37.037037037037, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=34.7107438016529, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=33.6996336996337, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787894, Length=334, Percent_Identity=30.8383233532934, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=29.4642857142857, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=26.530612244898, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788279, Length=305, Percent_Identity=27.2131147540984, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=26.9230769230769, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=28.6324786324786, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790861, Length=297, Percent_Identity=28.956228956229, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=330, Percent_Identity=24.8484848484848, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=29.5546558704453, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=345, Percent_Identity=28.4057971014493, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787374, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=23.9819004524887, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48994928, Length=222, Percent_Identity=27.4774774774775, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789403, Length=230, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=26.8085106382979, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790551, Length=304, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=31.0483870967742, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40056; Mature: 39925

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGIGARLFAAQAIVLTVGAATTSMAAAIVGPPLFRDHLHQAGVPPNSLEEMHAEEAYG
CCCCCCHHHHHHHHHHHEECHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHC
YATAISITGALAVSVLAALAVSWYLSRRLQRSITEVASAATAVADGRYDIRVSPPHLGED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
FDALAHAFNQMASQLQSVEVTRRRLFSDLAHEIRTPLAVLEAYFEAIEDGVRSLTPETAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MLRDQTGRLVRFAGDLGALARAEESSASMELEPIDIHSLVQRCAAAAQSGYSRKGVELCT
HHHHCCCCEEEECCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHE
AVDVDLPPLWGDEQRMSQVLANLLDNALRHTPSGGRVEISARRDGHRVLIRVSDNGEGIA
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCCH
AEHLPHVFERFYRADSARARQNGGAGIGLAIAKAVVEAHGGTIAADSAGAGRGTVFTVTV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEE
PVRASAPDLARRPPPTPVA
EEECCCCHHHCCCCCCCCC
>Mature Secondary Structure 
TAGIGARLFAAQAIVLTVGAATTSMAAAIVGPPLFRDHLHQAGVPPNSLEEMHAEEAYG
CCCCCHHHHHHHHHHHEECHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHC
YATAISITGALAVSVLAALAVSWYLSRRLQRSITEVASAATAVADGRYDIRVSPPHLGED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
FDALAHAFNQMASQLQSVEVTRRRLFSDLAHEIRTPLAVLEAYFEAIEDGVRSLTPETAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MLRDQTGRLVRFAGDLGALARAEESSASMELEPIDIHSLVQRCAAAAQSGYSRKGVELCT
HHHHCCCCEEEECCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHE
AVDVDLPPLWGDEQRMSQVLANLLDNALRHTPSGGRVEISARRDGHRVLIRVSDNGEGIA
EECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCCH
AEHLPHVFERFYRADSARARQNGGAGIGLAIAKAVVEAHGGTIAADSAGAGRGTVFTVTV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEE
PVRASAPDLARRPPPTPVA
EEECCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]