Click here to switch to the map view.

The map label for this gene is regX3 [H]

Identifier: 119868981

GI number: 119868981

Start: 3083127

End: 3083918

Strand: Direct

Name: regX3 [H]

Synonym: Mkms_2949

Alternate gene names: 119868981

Gene position: 3083127-3083918 (Clockwise)

Preceding gene: 119868980

Following gene: 119868982

Centisome position: 53.74

GC content: 68.94

Gene sequence:

>792_bases
ATGCGCGCGGGGGTCCCTCCGGCCGCGACGCCGGCGGGCACGATGGGATTCATGGAACAGTCGACCGGTTCAACGACTCG
CACCCACGGCTACCGCGCACTGGTGGTCGACGACGAGACCGCGTTGGCCGAGGTGGTGGCGAGCTATCTGGAGCGCGAGC
AGTTCGAGGCCTCCGTCGTCGGCAGCGGTGCGGAGGCCATCGCCGTCGCCCGCGGCCTCGATCCGGACGTCGTCATCCTC
GACATCGGCCTGCCGGGTATCGACGGCCTCGAGGTGTGCCGCCAGCTCCGCACCTTCTCGGACGCCTACGTGGTCATGCT
CACCGCCCGCAACACGGAACTGGACACGGTCCTCGGGCTGACCGTCGGCGCCGACGACTACGTCACGAAACCGTTCAGCC
CGCGGGAACTGGTGGCGCGCATCAGGGCCATGCTTCGGCGGCCCCGCATGCGTCCCGTCGCCGGCGCCGACACCGAGGAC
CTGCCGCCGCCACGAGTGTTCGGTCCGCTCAGCATCGATGTGGCGGCCCGTGAAGTAGGCCTCGACGGTGAATCGATCTT
GTTGACCCGCACGGAATTCGACATCCTGGAGGCGTTGTCCGCGCGGCCGGGGGTCGTGCTGAGTCGGCGCCAACTGCTCG
ACATCGTGCGCGAGGGGCCGTGGGTGGGTAACGAGCACCTCGTCGACGTCCACATCGGCCACCTGCGGCGCAAGCTCGGA
GACGACGCCGCTAACCCCCGGTTCATCATGACCGTGCGGGGTGTGGGCTACCGGATGGGAAGTTCCCGATGA

Upstream 100 bases:

>100_bases
ATCACTACGACCACGTCCACATCGCCACCAACGGCGGCGGCTTCCCCACTGGGCGCGAAACGTATTACCTCGAGTCGATG
AGCCCGGTGCCGCGGCCCTG

Downstream 100 bases:

>100_bases
CGGCCGGCATCGGCGCGCGACTGTTCGCAGCGCAGGCGATCGTGCTCACCGTCGGTGCGGCCACCACGTCGATGGCGGCC
GCGATCGTCGGACCACCCCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MRAGVPPAATPAGTMGFMEQSTGSTTRTHGYRALVVDDETALAEVVASYLEREQFEASVVGSGAEAIAVARGLDPDVVIL
DIGLPGIDGLEVCRQLRTFSDAYVVMLTARNTELDTVLGLTVGADDYVTKPFSPRELVARIRAMLRRPRMRPVAGADTED
LPPPRVFGPLSIDVAAREVGLDGESILLTRTEFDILEALSARPGVVLSRRQLLDIVREGPWVGNEHLVDVHIGHLRRKLG
DDAANPRFIMTVRGVGYRMGSSR

Sequences:

>Translated_263_residues
MRAGVPPAATPAGTMGFMEQSTGSTTRTHGYRALVVDDETALAEVVASYLEREQFEASVVGSGAEAIAVARGLDPDVVIL
DIGLPGIDGLEVCRQLRTFSDAYVVMLTARNTELDTVLGLTVGADDYVTKPFSPRELVARIRAMLRRPRMRPVAGADTED
LPPPRVFGPLSIDVAAREVGLDGESILLTRTEFDILEALSARPGVVLSRRQLLDIVREGPWVGNEHLVDVHIGHLRRKLG
DDAANPRFIMTVRGVGYRMGSSR
>Mature_263_residues
MRAGVPPAATPAGTMGFMEQSTGSTTRTHGYRALVVDDETALAEVVASYLEREQFEASVVGSGAEAIAVARGLDPDVVIL
DIGLPGIDGLEVCRQLRTFSDAYVVMLTARNTELDTVLGLTVGADDYVTKPFSPRELVARIRAMLRRPRMRPVAGADTED
LPPPRVFGPLSIDVAAREVGLDGESILLTRTEFDILEALSARPGVVLSRRQLLDIVREGPWVGNEHLVDVHIGHLRRKLG
DDAANPRFIMTVRGVGYRMGSSR

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=40.7894736842105, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=38.0952380952381, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=42.3580786026201, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=40, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=33.920704845815, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786599, Length=237, Percent_Identity=38.8185654008439, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.9307359307359, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.1931330472103, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI145693140, Length=225, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=34.5132743362832, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=236, Percent_Identity=33.8983050847458, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=34.4978165938865, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=33.7719298245614, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=32.3144104803493, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=31.404958677686, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28472; Mature: 28472

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGVPPAATPAGTMGFMEQSTGSTTRTHGYRALVVDDETALAEVVASYLEREQFEASVV
CCCCCCCCCCCCCCHHHHHCCCCCCEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHC
GSGAEAIAVARGLDPDVVILDIGLPGIDGLEVCRQLRTFSDAYVVMLTARNTELDTVLGL
CCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEE
TVGADDYVTKPFSPRELVARIRAMLRRPRMRPVAGADTEDLPPPRVFGPLSIDVAAREVG
EECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCEEEEEHHHHHC
LDGESILLTRTEFDILEALSARPGVVLSRRQLLDIVREGPWVGNEHLVDVHIGHLRRKLG
CCCCEEEEEECHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHC
DDAANPRFIMTVRGVGYRMGSSR
CCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRAGVPPAATPAGTMGFMEQSTGSTTRTHGYRALVVDDETALAEVVASYLEREQFEASVV
CCCCCCCCCCCCCCHHHHHCCCCCCEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHC
GSGAEAIAVARGLDPDVVILDIGLPGIDGLEVCRQLRTFSDAYVVMLTARNTELDTVLGL
CCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEE
TVGADDYVTKPFSPRELVARIRAMLRRPRMRPVAGADTEDLPPPRVFGPLSIDVAAREVG
EECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCEEEEEHHHHHC
LDGESILLTRTEFDILEALSARPGVVLSRRQLLDIVREGPWVGNEHLVDVHIGHLRRKLG
CCCCEEEEEECHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHC
DDAANPRFIMTVRGVGYRMGSSR
CCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA