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The map label for this gene is ytfL [C]

Identifier: 119868891

GI number: 119868891

Start: 2979406

End: 2980461

Strand: Direct

Name: ytfL [C]

Synonym: Mkms_2859

Alternate gene names: 119868891

Gene position: 2979406-2980461 (Clockwise)

Preceding gene: 119868890

Following gene: 119868892

Centisome position: 51.93

GC content: 69.13

Gene sequence:

>1056_bases
ATGGGTGGCGATCTGTTCGGCGTCCTGCTGACCGTGCTGCTGCTGGGGGCCAACGCGTTCTTCGTGGCCTCCGAGTTCGC
GCTCATCTCCGCGCGCCGCGACCGGCTCGAGGCCCTGGCGGAACAGGGCAAGAACAGCGCGGTGACCGTCATCCGGGCCG
GTGAGAACCTCTCGCTGATGCTGGCCGGTTCCCAGCTGGGCATCACGATCTGTTCCATCCTGCTGGGCCGGGTCGGCGAA
CCCGCGGTGGCGCACCTGCTGGAGAAACCCTTCGGGTTGCTCGGCATCCCGGACGCGGTGCTGCACACCGTCTCGTTCGT
GGTCGCGTTGAGCGTGGTGGTCACGCTGCACGTGCTGCTGGGTGAGATGGTTCCGAAGAACATCGCGATCGCGGGGCCGG
AGTCGGCGGCGATGCTGCTGATCCCGGTCTACCTGGTCTACATCCGTGCGGCGCGCCCGCTCATCGCGTTCTACAACTGG
TGCGCGAACGCCACGCTGCGCGCCTTCGGGGTGGAGCCGAAGGACGAACTCGACGTCAACGTCTCGACGGTCGAACTGTC
GGAGATGATCGCCGAATCGGTCTCCGAAGGTCTGCTCGACCCCGAGGAGCACACACGGCTCACCCGCGCCCTGCAGATCC
GCAACCGGGCCGTCCGGGATGTGGCGATGCCGCTGGACACCATCCACGCCATCCCGGCGTCGGCACCGGGTCAGGGCCCG
ACGGTCGCCGCTGTGGAACGGGCGCTGGCCGAGACGGGCTACTCCCGGTTCCCCGTGACCGCGCCGTCCGGCCAGTACCT
GGGCTATCTGCACATCAAGGATGTCCTGCCGCTGGTCGACGATCCCGATGCGGTGCTGGACCGGTCGATGGTGCGCCCGC
TGCCGCAGCTGCCCGCATCGCTGCCGCTACCCGACGCCCTGTCCCGGCTGCGCCGCACCAACAGCCACCTCGCGCTGGTC
ACCTCCGCCGACGGTGCGGTCACCGCGATGGTGGCGCTGGAAGACCTGGTGGAGGACCTCGTCGGCACCGTGCGCGACGG
AACCCACCGGCGGTGA

Upstream 100 bases:

>100_bases
AGTTGGTCGAACTCGGGCGCCGCGGCGACACCGACGACGACCACATCGACAACGACGACCACCACAACAAAGACGGCGCC
GCGCCGGAGGAGGACCGCTG

Downstream 100 bases:

>100_bases
TGACCCAACTCCTCGACGAGTCGGTGTGGGTGCGGCGGGCGAGCACCCACCGTGATCGGGTGGACGCCTTCTGCGCGCCG
CATCAGGCGCGGCGACGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MGGDLFGVLLTVLLLGANAFFVASEFALISARRDRLEALAEQGKNSAVTVIRAGENLSLMLAGSQLGITICSILLGRVGE
PAVAHLLEKPFGLLGIPDAVLHTVSFVVALSVVVTLHVLLGEMVPKNIAIAGPESAAMLLIPVYLVYIRAARPLIAFYNW
CANATLRAFGVEPKDELDVNVSTVELSEMIAESVSEGLLDPEEHTRLTRALQIRNRAVRDVAMPLDTIHAIPASAPGQGP
TVAAVERALAETGYSRFPVTAPSGQYLGYLHIKDVLPLVDDPDAVLDRSMVRPLPQLPASLPLPDALSRLRRTNSHLALV
TSADGAVTAMVALEDLVEDLVGTVRDGTHRR

Sequences:

>Translated_351_residues
MGGDLFGVLLTVLLLGANAFFVASEFALISARRDRLEALAEQGKNSAVTVIRAGENLSLMLAGSQLGITICSILLGRVGE
PAVAHLLEKPFGLLGIPDAVLHTVSFVVALSVVVTLHVLLGEMVPKNIAIAGPESAAMLLIPVYLVYIRAARPLIAFYNW
CANATLRAFGVEPKDELDVNVSTVELSEMIAESVSEGLLDPEEHTRLTRALQIRNRAVRDVAMPLDTIHAIPASAPGQGP
TVAAVERALAETGYSRFPVTAPSGQYLGYLHIKDVLPLVDDPDAVLDRSMVRPLPQLPASLPLPDALSRLRRTNSHLALV
TSADGAVTAMVALEDLVEDLVGTVRDGTHRR
>Mature_350_residues
GGDLFGVLLTVLLLGANAFFVASEFALISARRDRLEALAEQGKNSAVTVIRAGENLSLMLAGSQLGITICSILLGRVGEP
AVAHLLEKPFGLLGIPDAVLHTVSFVVALSVVVTLHVLLGEMVPKNIAIAGPESAAMLLIPVYLVYIRAARPLIAFYNWC
ANATLRAFGVEPKDELDVNVSTVELSEMIAESVSEGLLDPEEHTRLTRALQIRNRAVRDVAMPLDTIHAIPASAPGQGPT
VAAVERALAETGYSRFPVTAPSGQYLGYLHIKDVLPLVDDPDAVLDRSMVRPLPQLPASLPLPDALSRLRRTNSHLALVT
SADGAVTAMVALEDLVEDLVGTVRDGTHRR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=340, Percent_Identity=31.4705882352941, Blast_Score=177, Evalue=1e-44,
Organism=Escherichia coli, GI1790664, Length=341, Percent_Identity=23.7536656891496, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693175, Length=336, Percent_Identity=23.5119047619048, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR002550 [H]

Pfam domain/function: PF00571 CBS; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 37401; Mature: 37270

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGDLFGVLLTVLLLGANAFFVASEFALISARRDRLEALAEQGKNSAVTVIRAGENLSLM
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEE
LAGSQLGITICSILLGRVGEPAVAHLLEKPFGLLGIPDAVLHTVSFVVALSVVVTLHVLL
EECCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GEMVPKNIAIAGPESAAMLLIPVYLVYIRAARPLIAFYNWCANATLRAFGVEPKDELDVN
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHCCCC
VSTVELSEMIAESVSEGLLDPEEHTRLTRALQIRNRAVRDVAMPLDTIHAIPASAPGQGP
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TVAAVERALAETGYSRFPVTAPSGQYLGYLHIKDVLPLVDDPDAVLDRSMVRPLPQLPAS
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHCCCCCCCCC
LPLPDALSRLRRTNSHLALVTSADGAVTAMVALEDLVEDLVGTVRDGTHRR
CCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GGDLFGVLLTVLLLGANAFFVASEFALISARRDRLEALAEQGKNSAVTVIRAGENLSLM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEE
LAGSQLGITICSILLGRVGEPAVAHLLEKPFGLLGIPDAVLHTVSFVVALSVVVTLHVLL
EECCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GEMVPKNIAIAGPESAAMLLIPVYLVYIRAARPLIAFYNWCANATLRAFGVEPKDELDVN
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHCCCC
VSTVELSEMIAESVSEGLLDPEEHTRLTRALQIRNRAVRDVAMPLDTIHAIPASAPGQGP
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TVAAVERALAETGYSRFPVTAPSGQYLGYLHIKDVLPLVDDPDAVLDRSMVRPLPQLPAS
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHCCCCCCCCC
LPLPDALSRLRRTNSHLALVTSADGAVTAMVALEDLVEDLVGTVRDGTHRR
CCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]