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The map label for this gene is yfjD [C]

Identifier: 119868890

GI number: 119868890

Start: 2977991

End: 2979406

Strand: Direct

Name: yfjD [C]

Synonym: Mkms_2858

Alternate gene names: 119868890

Gene position: 2977991-2979406 (Clockwise)

Preceding gene: 119868889

Following gene: 119868891

Centisome position: 51.91

GC content: 69.92

Gene sequence:

>1416_bases
ATGAGCGTCGCATACACCCTGCTCTCGCTGTTGGCGATCGTGGTGTTGACCGCGGGTACCGCGGTGTTCGTCGCCGCCGA
GTTCTCGTTGACGGCGCTGGAGCGCAGCACCGTCGAGGCCAATGCCCGTAGCGGGCACCGGCGCGACCAGCTCGTGCGCC
GCGCCCACCGCACGCTGTCCTTCCAGCTCTCGGGCGCCCAGGTGGGCATCTCGATCACCACGCTGGCCACCGGCTACCTG
GCCGAACCCGTGGTCGCCCGGCTGCTGCAGCCGGGTCTGGACGCGATCGGACTGCCGGAACAGGCCGCGAGCGGCGTCGC
CCTGTTCCTCGCGATCCTGATCGCCACCTCCCTGTCGATGGTCTTCGGCGAACTCGTGCCGAAGAACCTCGCGGTGGCCC
GCCCGGCGCCGACCGCCCGCGCAGCCGCACCTCCGCAGCTGCTCTTCTCGACGATCTTCACGCCGCTGATCCGGCTCACC
AACGGCACCGCGAACATGATCCTGCGCCGGCTGGGCATCGAACCCGCCGAGGAACTGCGCTCCGCGCGGTCGGTGCAGGA
GCTGATCTCGCTGGTGCGCAACTCCGCGCGCAGCGGTTCACTCGACCCGGTGACCGCGGTGCTGGTGGACAGGTCACTGC
AGTTCGGCGAGCGCACCGCCGAGGAACTGATGACCCCCCGCACCGAGATCGAGGCCCTGCAGGCCGACGACACCGTCGCC
GACCTCATCGCCGCGGCGATCGAAACGGGGTATTCGCGCTTCCCGATCGTCGAGGGTGACCTCGACGAGACCATCGGCGT
CGTCCACGTCAAACAGGTGTTCTCGGTACCGCGCGACGACCGCGACCGCACCCGCCTCGCGGCAATCGCGATCCCGGTGG
CCACCGTGCCCTCGACGCTGGACGGGGACGCGGTGATGACCCAGATCCGCGCCAACGGGCTGCAGACCGCGCTGGTGGTC
GACGAGTACGGCGGCACCGCCGGCATGGTGACCGTCGAGGATCTGATCGAGGAGATCGTCGGCGACGTCCGCGACGAACA
CGATGACGCCACCCCCGACGTGGTCGCCGCCGGCGACGGCTGGCAGGTGTCGGGCCTGCTGCGGATCGACGAGGTGGCCA
CCGGGACCGGTTTCCGCGCCCCCGAGGGCGAGTACGAGACCATCGGCGGGCTGGTGCTGCAGGAGCTCGGACACATCCCG
GAAGTGGGCGACTCGGTCGAGCTGACCGCGTTCGATCCGGACGGGCCGCTCGACGATCCGATCCGCTGGCAGGCCAAGGT
CGTGCAGATGGACGGTCGCCGGATCGACCTTCTGGAGTTGGTCGAACTCGGGCGCCGCGGCGACACCGACGACGACCACA
TCGACAACGACGACCACCACAACAAAGACGGCGCCGCGCCGGAGGAGGACCGCTGA

Upstream 100 bases:

>100_bases
CGGAGGCCTGCCGGGCCGAGCACCCGTCCATCGAGCCACCCGACGCCGAGCCCTCTTCTAGCCGGCCGGGCCCACGGCCC
GGCGTACCGGTGACGATTCG

Downstream 100 bases:

>100_bases
TGGGTGGCGATCTGTTCGGCGTCCTGCTGACCGTGCTGCTGCTGGGGGCCAACGCGTTCTTCGTGGCCTCCGAGTTCGCG
CTCATCTCCGCGCGCCGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSVAYTLLSLLAIVVLTAGTAVFVAAEFSLTALERSTVEANARSGHRRDQLVRRAHRTLSFQLSGAQVGISITTLATGYL
AEPVVARLLQPGLDAIGLPEQAASGVALFLAILIATSLSMVFGELVPKNLAVARPAPTARAAAPPQLLFSTIFTPLIRLT
NGTANMILRRLGIEPAEELRSARSVQELISLVRNSARSGSLDPVTAVLVDRSLQFGERTAEELMTPRTEIEALQADDTVA
DLIAAAIETGYSRFPIVEGDLDETIGVVHVKQVFSVPRDDRDRTRLAAIAIPVATVPSTLDGDAVMTQIRANGLQTALVV
DEYGGTAGMVTVEDLIEEIVGDVRDEHDDATPDVVAAGDGWQVSGLLRIDEVATGTGFRAPEGEYETIGGLVLQELGHIP
EVGDSVELTAFDPDGPLDDPIRWQAKVVQMDGRRIDLLELVELGRRGDTDDDHIDNDDHHNKDGAAPEEDR

Sequences:

>Translated_471_residues
MSVAYTLLSLLAIVVLTAGTAVFVAAEFSLTALERSTVEANARSGHRRDQLVRRAHRTLSFQLSGAQVGISITTLATGYL
AEPVVARLLQPGLDAIGLPEQAASGVALFLAILIATSLSMVFGELVPKNLAVARPAPTARAAAPPQLLFSTIFTPLIRLT
NGTANMILRRLGIEPAEELRSARSVQELISLVRNSARSGSLDPVTAVLVDRSLQFGERTAEELMTPRTEIEALQADDTVA
DLIAAAIETGYSRFPIVEGDLDETIGVVHVKQVFSVPRDDRDRTRLAAIAIPVATVPSTLDGDAVMTQIRANGLQTALVV
DEYGGTAGMVTVEDLIEEIVGDVRDEHDDATPDVVAAGDGWQVSGLLRIDEVATGTGFRAPEGEYETIGGLVLQELGHIP
EVGDSVELTAFDPDGPLDDPIRWQAKVVQMDGRRIDLLELVELGRRGDTDDDHIDNDDHHNKDGAAPEEDR
>Mature_470_residues
SVAYTLLSLLAIVVLTAGTAVFVAAEFSLTALERSTVEANARSGHRRDQLVRRAHRTLSFQLSGAQVGISITTLATGYLA
EPVVARLLQPGLDAIGLPEQAASGVALFLAILIATSLSMVFGELVPKNLAVARPAPTARAAAPPQLLFSTIFTPLIRLTN
GTANMILRRLGIEPAEELRSARSVQELISLVRNSARSGSLDPVTAVLVDRSLQFGERTAEELMTPRTEIEALQADDTVAD
LIAAAIETGYSRFPIVEGDLDETIGVVHVKQVFSVPRDDRDRTRLAAIAIPVATVPSTLDGDAVMTQIRANGLQTALVVD
EYGGTAGMVTVEDLIEEIVGDVRDEHDDATPDVVAAGDGWQVSGLLRIDEVATGTGFRAPEGEYETIGGLVLQELGHIPE
VGDSVELTAFDPDGPLDDPIRWQAKVVQMDGRRIDLLELVELGRRGDTDDDHIDNDDHHNKDGAAPEEDR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=382, Percent_Identity=32.1989528795811, Blast_Score=212, Evalue=6e-55,
Organism=Escherichia coli, GI145693175, Length=406, Percent_Identity=25.3694581280788, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786879, Length=255, Percent_Identity=28.2352941176471, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790664, Length=443, Percent_Identity=24.3792325056433, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=30.379746835443, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87082033, Length=358, Percent_Identity=24.8603351955307, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50390; Mature: 50258

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAYTLLSLLAIVVLTAGTAVFVAAEFSLTALERSTVEANARSGHRRDQLVRRAHRTLS
CCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEE
FQLSGAQVGISITTLATGYLAEPVVARLLQPGLDAIGLPEQAASGVALFLAILIATSLSM
EEECCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VFGELVPKNLAVARPAPTARAAAPPQLLFSTIFTPLIRLTNGTANMILRRLGIEPAEELR
HHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
SARSVQELISLVRNSARSGSLDPVTAVLVDRSLQFGERTAEELMTPRTEIEALQADDTVA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
DLIAAAIETGYSRFPIVEGDLDETIGVVHVKQVFSVPRDDRDRTRLAAIAIPVATVPSTL
HHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEHHHCCCCC
DGDAVMTQIRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGDVRDEHDDATPDVVAAGDG
CCHHHHHHHHHCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEECCCC
WQVSGLLRIDEVATGTGFRAPEGEYETIGGLVLQELGHIPEVGDSVELTAFDPDGPLDDP
EEEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
IRWQAKVVQMDGRRIDLLELVELGRRGDTDDDHIDNDDHHNKDGAAPEEDR
HHHHEEEEEECCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVAYTLLSLLAIVVLTAGTAVFVAAEFSLTALERSTVEANARSGHRRDQLVRRAHRTLS
CHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEE
FQLSGAQVGISITTLATGYLAEPVVARLLQPGLDAIGLPEQAASGVALFLAILIATSLSM
EEECCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VFGELVPKNLAVARPAPTARAAAPPQLLFSTIFTPLIRLTNGTANMILRRLGIEPAEELR
HHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
SARSVQELISLVRNSARSGSLDPVTAVLVDRSLQFGERTAEELMTPRTEIEALQADDTVA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
DLIAAAIETGYSRFPIVEGDLDETIGVVHVKQVFSVPRDDRDRTRLAAIAIPVATVPSTL
HHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEHHHCCCCC
DGDAVMTQIRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGDVRDEHDDATPDVVAAGDG
CCHHHHHHHHHCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEECCCC
WQVSGLLRIDEVATGTGFRAPEGEYETIGGLVLQELGHIPEVGDSVELTAFDPDGPLDDP
EEEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
IRWQAKVVQMDGRRIDLLELVELGRRGDTDDDHIDNDDHHNKDGAAPEEDR
HHHHEEEEEECCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]