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The map label for this gene is ycgM [C]

Identifier: 119868683

GI number: 119868683

Start: 2782369

End: 2783334

Strand: Direct

Name: ycgM [C]

Synonym: Mkms_2650

Alternate gene names: 119868683

Gene position: 2782369-2783334 (Clockwise)

Preceding gene: 119868682

Following gene: 119868684

Centisome position: 48.5

GC content: 65.22

Gene sequence:

>966_bases
ATGAAGATAGCAACCGTACTGGCCGCGGGCCGTCCCGTGGTGACTGCGCTCGGTCCGGCTGAGCAGTTGGTCAACGTCGC
CCGGCTGCTCAGCTTGCCCGACCTGACGGTGGCGACCTTGATCGCCGACGCCGACCGACTCCTGCCGAAACTGGCCGCAG
CGCTGAGCGAACCCGTGGCGGCGGAGGCAGTCTTGGACAGTGCCGACATCTCCTGGCTGGCGCCGCAACCCCACCCCTCC
AAGATCGTCGGTGTCGCGGTCAACAACAGCGGCATCGCGCGATTCGCCTATCGGCAGCACGTCGAGCCGGCGTACTTCTT
GAAGCCGCCGTCGGCACTGACCGGCCACCGGGAGCCCATCGTCGTGCCACCGGATTACGGCCTGACCCACCCGGAACCCG
AGCTGGCGGCCATCATCGGCCGTCGCATCAAAGCGGCCCAGCCAGAGCAGGCACTCGAGGCCATCTTCGGCTACACGATC
ATCAACGACATCACCTCCCCGGCACTCAAAGACCGCGACAGCATGGAGTTGCGGTTGCCCAGCCCGGTCGGGGCTGATCT
CACCTGGCGAGAAACCCACGGCGAGAAGGATTCCTCGCTGTATCTGACCTACCACGCGCGATCCAAAGGGTCCGACACCT
TCGCCCCGATGGGACCGTGGATCACCACCCGCGACGAGGTGGTCGACCCCAATGCCCTGGCGGTGGACTGCTGGCTCGAC
GACGAGCTCGTCGTGAGTGACTCGACGAGCAAGTTGACGTTTCCCATCCAGGACGTCATCGCACACCTGTCGAACTACAT
GACCCTCGAGCCCGGCGATGTGGTGCACTTCGGCACGGCAGTTCAACCAGGCGCAAATCCGAAGTTCCCGACGCTGCGCC
ACCTCGACATGAGCAGTCTGGACGGCACGTTGTCGGTGGAGATCACCGGGCTCGGCCGTCTGGACAACCCGATCGCGCAC
GAGTGA

Upstream 100 bases:

>100_bases
ACACCGGTGCCGCTCATACCTATAGCGATTACGACATCGCCGCGCAGGTCTACGGTGCTCATCTGGCAGCCGTGCAGCCG
CAAGAGGGGCTTTTCTAGCC

Downstream 100 bases:

>100_bases
CCGTCATGTCGACCACCTCCGTAGAGCTCTGGCCCGCCTTGACCGGTCCCGCCGACCTGCACAAGGTCGAGGCGACTCCC
CTCGCGGTTCGCGGGGTGCC

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKIATVLAAGRPVVTALGPAEQLVNVARLLSLPDLTVATLIADADRLLPKLAAALSEPVAAEAVLDSADISWLAPQPHPS
KIVGVAVNNSGIARFAYRQHVEPAYFLKPPSALTGHREPIVVPPDYGLTHPEPELAAIIGRRIKAAQPEQALEAIFGYTI
INDITSPALKDRDSMELRLPSPVGADLTWRETHGEKDSSLYLTYHARSKGSDTFAPMGPWITTRDEVVDPNALAVDCWLD
DELVVSDSTSKLTFPIQDVIAHLSNYMTLEPGDVVHFGTAVQPGANPKFPTLRHLDMSSLDGTLSVEITGLGRLDNPIAH
E

Sequences:

>Translated_321_residues
MKIATVLAAGRPVVTALGPAEQLVNVARLLSLPDLTVATLIADADRLLPKLAAALSEPVAAEAVLDSADISWLAPQPHPS
KIVGVAVNNSGIARFAYRQHVEPAYFLKPPSALTGHREPIVVPPDYGLTHPEPELAAIIGRRIKAAQPEQALEAIFGYTI
INDITSPALKDRDSMELRLPSPVGADLTWRETHGEKDSSLYLTYHARSKGSDTFAPMGPWITTRDEVVDPNALAVDCWLD
DELVVSDSTSKLTFPIQDVIAHLSNYMTLEPGDVVHFGTAVQPGANPKFPTLRHLDMSSLDGTLSVEITGLGRLDNPIAH
E
>Mature_321_residues
MKIATVLAAGRPVVTALGPAEQLVNVARLLSLPDLTVATLIADADRLLPKLAAALSEPVAAEAVLDSADISWLAPQPHPS
KIVGVAVNNSGIARFAYRQHVEPAYFLKPPSALTGHREPIVVPPDYGLTHPEPELAAIIGRRIKAAQPEQALEAIFGYTI
INDITSPALKDRDSMELRLPSPVGADLTWRETHGEKDSSLYLTYHARSKGSDTFAPMGPWITTRDEVVDPNALAVDCWLD
DELVVSDSTSKLTFPIQDVIAHLSNYMTLEPGDVVHFGTAVQPGANPKFPTLRHLDMSSLDGTLSVEITGLGRLDNPIAH
E

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=220, Percent_Identity=30.4545454545455, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI40786394, Length=220, Percent_Identity=30.4545454545455, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1787428, Length=209, Percent_Identity=27.7511961722488, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28572127, Length=262, Percent_Identity=26.7175572519084, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 34541; Mature: 34541

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIATVLAAGRPVVTALGPAEQLVNVARLLSLPDLTVATLIADADRLLPKLAAALSEPVA
CCEEEEEECCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
AEAVLDSADISWLAPQPHPSKIVGVAVNNSGIARFAYRQHVEPAYFLKPPSALTGHREPI
HHHHHCCCCCEEECCCCCCCCEEEEEECCCCCEEHHHHHCCCCEEEECCCCHHCCCCCCE
VVPPDYGLTHPEPELAAIIGRRIKAAQPEQALEAIFGYTIINDITSPALKDRDSMELRLP
EECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEECC
SPVGADLTWRETHGEKDSSLYLTYHARSKGSDTFAPMGPWITTRDEVVDPNALAVDCWLD
CCCCCCEEEHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
DELVVSDSTSKLTFPIQDVIAHLSNYMTLEPGDVVHFGTAVQPGANPKFPTLRHLDMSSL
CEEEEECCCCEEEECHHHHHHHHHCCEEECCCCEEEECCEECCCCCCCCCCEEECCCCCC
DGTLSVEITGLGRLDNPIAHE
CCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKIATVLAAGRPVVTALGPAEQLVNVARLLSLPDLTVATLIADADRLLPKLAAALSEPVA
CCEEEEEECCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
AEAVLDSADISWLAPQPHPSKIVGVAVNNSGIARFAYRQHVEPAYFLKPPSALTGHREPI
HHHHHCCCCCEEECCCCCCCCEEEEEECCCCCEEHHHHHCCCCEEEECCCCHHCCCCCCE
VVPPDYGLTHPEPELAAIIGRRIKAAQPEQALEAIFGYTIINDITSPALKDRDSMELRLP
EECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEECC
SPVGADLTWRETHGEKDSSLYLTYHARSKGSDTFAPMGPWITTRDEVVDPNALAVDCWLD
CCCCCCEEEHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
DELVVSDSTSKLTFPIQDVIAHLSNYMTLEPGDVVHFGTAVQPGANPKFPTLRHLDMSSL
CEEEEECCCCEEEECHHHHHHHHHCCEEECCCCEEEECCEECCCCCCCCCCEEECCCCCC
DGTLSVEITGLGRLDNPIAHE
CCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]