Click here to switch to the map view.

The map label for this gene is agaR [H]

Identifier: 119868505

GI number: 119868505

Start: 2593544

End: 2594320

Strand: Reverse

Name: agaR [H]

Synonym: Mkms_2470

Alternate gene names: 119868505

Gene position: 2594320-2593544 (Counterclockwise)

Preceding gene: 119868506

Following gene: 119868502

Centisome position: 45.22

GC content: 70.66

Gene sequence:

>777_bases
GTGCCCACACTGAACGCGCACGCCCGGCGGACGGCGATCGCCGCCAGGATCAACGCCGACCGCGAAGTCGACTTCGCCTC
GCTCGCCGAGGAATTCGACGTCTCGGAGATGACGATCCGGCGCGACATCGAGCGGCTGGAGGACCAGGGCATCGCCCGGC
GCGTGCTCGGCGGCGCGATCGCGTTCGGCGGCAAGTCGACCGAGCCGTCGTTCGCCGCCCGCGCGGCCGAGGCGGCCGAC
GAGAAGATCCACATCGCCAGCGCGGTGGCCGATCTGCTGACCCCGCAGGAGACGGTCATCCTCGACAGCGGCAGCACCGT
GCTGGCGGTGGCCCGGGCGATCAAGGGCCGCGGGCTGGGCCTGACGGTGATCACGCCGAGCGTCCTGGTCGCCGTGGAGC
TCGCCGATGAACCCGATACCACGATCCTGCTCACCGGCGGGAAGGTCCGCCCCGGCGAGCTGAGCCTCATCGGCGCCGAG
GCGGAGGACTTCTACCTGCGCTACAACTGCGACACCTACGTGATGGGCATCGCCGGCGTCGACGGCAGACGCGGCGCGTC
GGAGTACCACCGCGAAGAAGGCAACGTCAAACAGGCGGCGATGCGGTCGGCCGACCGGGTCATCGTGGCCGCCGACGCCA
CCAAACTCGGGCGCGTGCAGCTGATCAACGTCGCTCCGGTGTCCGACATCTCGGTGTTGGTCACCGACGGGCCGTGCGAA
CACCCCACGCTGGAGTCGTTGCGCGCCGCGGGCGTCCAGGTGGTCTGCGTCGGCTGA

Upstream 100 bases:

>100_bases
GGCCCGAACTAGTCAGCCTCTCCCCCGTTCCGTGGTCCAGGTTCCGTAACGATCATGTGATCGGTGTGAAACTTTCACAC
ATCTGGCCTACGCTGGAGCG

Downstream 100 bases:

>100_bases
TCAACCCCAGCGGGCCGAGACGGTCTCGTCACCGTCGGCCGGCCGGCACACCGTCGCACCCGCCTCCTCGGCGATGAGCG
CACCGGCGGCCCAGTCGTGC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPTLNAHARRTAIAARINADREVDFASLAEEFDVSEMTIRRDIERLEDQGIARRVLGGAIAFGGKSTEPSFAARAAEAAD
EKIHIASAVADLLTPQETVILDSGSTVLAVARAIKGRGLGLTVITPSVLVAVELADEPDTTILLTGGKVRPGELSLIGAE
AEDFYLRYNCDTYVMGIAGVDGRRGASEYHREEGNVKQAAMRSADRVIVAADATKLGRVQLINVAPVSDISVLVTDGPCE
HPTLESLRAAGVQVVCVG

Sequences:

>Translated_258_residues
MPTLNAHARRTAIAARINADREVDFASLAEEFDVSEMTIRRDIERLEDQGIARRVLGGAIAFGGKSTEPSFAARAAEAAD
EKIHIASAVADLLTPQETVILDSGSTVLAVARAIKGRGLGLTVITPSVLVAVELADEPDTTILLTGGKVRPGELSLIGAE
AEDFYLRYNCDTYVMGIAGVDGRRGASEYHREEGNVKQAAMRSADRVIVAADATKLGRVQLINVAPVSDISVLVTDGPCE
HPTLESLRAAGVQVVCVG
>Mature_257_residues
PTLNAHARRTAIAARINADREVDFASLAEEFDVSEMTIRRDIERLEDQGIARRVLGGAIAFGGKSTEPSFAARAAEAADE
KIHIASAVADLLTPQETVILDSGSTVLAVARAIKGRGLGLTVITPSVLVAVELADEPDTTILLTGGKVRPGELSLIGAEA
EDFYLRYNCDTYVMGIAGVDGRRGASEYHREEGNVKQAAMRSADRVIVAADATKLGRVQLINVAPVSDISVLVTDGPCEH
PTLESLRAAGVQVVCVG

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=32.5396825396825, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=32.3275862068966, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=29.718875502008, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI226510968, Length=228, Percent_Identity=32.0175438596491, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=28.2868525896414, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082344, Length=209, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787540, Length=251, Percent_Identity=25.8964143426295, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787063, Length=221, Percent_Identity=26.2443438914027, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790635, Length=241, Percent_Identity=24.896265560166, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27246; Mature: 27115

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLNAHARRTAIAARINADREVDFASLAEEFDVSEMTIRRDIERLEDQGIARRVLGGAI
CCCCCCHHHHHEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCE
AFGGKSTEPSFAARAAEAADEKIHIASAVADLLTPQETVILDSGSTVLAVARAIKGRGLG
EECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCE
LTVITPSVLVAVELADEPDTTILLTGGKVRPGELSLIGAEAEDFYLRYNCDTYVMGIAGV
EEEECCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCEEEEEECCCEEEEEEECC
DGRRGASEYHREEGNVKQAAMRSADRVIVAADATKLGRVQLINVAPVSDISVLVTDGPCE
CCCCCCHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCC
HPTLESLRAAGVQVVCVG
CCCHHHHHHCCEEEEEEC
>Mature Secondary Structure 
PTLNAHARRTAIAARINADREVDFASLAEEFDVSEMTIRRDIERLEDQGIARRVLGGAI
CCCCCHHHHHEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCE
AFGGKSTEPSFAARAAEAADEKIHIASAVADLLTPQETVILDSGSTVLAVARAIKGRGLG
EECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCE
LTVITPSVLVAVELADEPDTTILLTGGKVRPGELSLIGAEAEDFYLRYNCDTYVMGIAGV
EEEECCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEECCCCEEEEEECCCEEEEEEECC
DGRRGASEYHREEGNVKQAAMRSADRVIVAADATKLGRVQLINVAPVSDISVLVTDGPCE
CCCCCCHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCC
HPTLESLRAAGVQVVCVG
CCCHHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]