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The map label for this gene is yebQ [C]

Identifier: 119868470

GI number: 119868470

Start: 2553604

End: 2555271

Strand: Reverse

Name: yebQ [C]

Synonym: Mkms_2434

Alternate gene names: 119868470

Gene position: 2555271-2553604 (Counterclockwise)

Preceding gene: 119868471

Following gene: 119868460

Centisome position: 44.54

GC content: 69.48

Gene sequence:

>1668_bases
ATGCAGCCCACCGAGGTCGGGCCGGCCATCGCACCGGCGAACAGCCGAAGCCGTCGGATCGCGATCAGCGCGGGCAGTCT
CGCGGTCCTGCTCGGCGCGCTCGACACCTATGTCGTCATCGCGATCATCCGCGACATCATGTTCGACATCGGGATCGCGA
TAAACCAGATCCAACGCGTCACGCCGATCATCACCGGGTACCTGCTCGGCTACATCGCCGCGATGCCGCTGCTGGGCCGG
GCGTCCGACCGGTTCGGACGCAAGCTGGTGCTGCAGCTCAGCCTGGCCGGCTTCGCGATCGGGTCGGTGGTCACGGCGTT
GTCGAATGACCTGACACCCATGGTGATCGGCCGCTTCATCCAGGGTGTGGCCAGCGGCGCACTGCTGCCGGTCACCCTGG
CACTGGCCGCCGACCTGTGGGCGACCCGCAACCGCGCCTCGGTGCTCGGCGGGATCGGCGCGGCGCAGGAACTGGGCAGC
GTGCTGGGCCCGCTCTACGGAATCGCCGTGGTGGCCGCGCTGAGCACCTGGCGTGACGTGTTCTGGATCAACGTGCCGCT
CGCGGCGATCGCGATGGTGCTGATCCACTTCAGCCTGCCTGCCCGTCTCAAACCGGAGCGACCGGAGAAGGTCGACGTGG
TCGGCGGCGTCCTGCTGGCGATTGCGCTCGGCCTGTCGGTGATCGGCCTGTACAACCCGGCCCCCGACGGCAAACAGATC
CTGCCCGACTACGGCCCGCCGACGCTGATCGGCGCCGTCGCCGCGTTCGTGGCCTTCTTCGTGTGGGAGCGATTCGCCCG
CACCCGTCTGATCGAACCGGCCGGTGTGCACTTCCGGCCGTTCCTGGCGGCGTTGGGCGCGTCGCTCTGCGCGGGTGCGG
CGCTGATGGTCACGCTGGTCAACGTCGAACTCTTCGGCCAGGGCGTGCTCGGCAAGGATCAGACGGAGGCCGTCCTGCTC
CTGCTTCGGTTCCTGATCGCCCTGCCGATCGGAGCGCTGCTCGGTGGCTGGCTGGCCAGCCGCATCGGTGACCGGCTGGT
GGCGTTCGCCGGCCTGATGATCGCCGCGGGCGGATACCTGTTGATCTCGAAGTGGCCGGTCGACCTGCTCTCGGCCCGTC
ACGATCTCGGGTTCGTCACCCTGCCGGTCCTCGACACCGACCTGGTGATCGCCGGGATCGGCCTCGGCCTGGTGATCGGT
CCGCTGACGTCGGCGTCGCTGCGGGTGGTGCCCGCCGCACAGCACGGCATCGCGTCGGCCGCGGTGGTGGTGTCCCGGAT
GATCGGCATGCTGATCGGGCTGGCGGCGCTGTCCGCGTGGGGGCTGTACCGGCTCAACCAGCACCTGCAGACGCTGCCGT
TCCCGCCCGGGGCCGACACGCTGGCCGAGCGGTTGGCCGCCGAGGCGGACCGCTACCGCGCGGCGTACGTGCTGCAGTAC
GGCGACATCTTCATCGTCACCACGATCATCTGTGTGGTCGGCGCACTGCTCGGGCTGCTGATCAGCGGCAGGAACGAGCA
TGCGGACGAGTCCCCGGTGCCCGTGGGTGCCGATCACGGGGACGATGCGCCCACCCAGTTCATCAACGTGGCAGGCGCCT
CGGGAGACGCCGATCAGACCACGCGCCTACCGCGGCAGACACCGGGCAGGCACCGCGACGAAGCCTGA

Upstream 100 bases:

>100_bases
ACCTGGCGCAGGTCAAGTTGGAGCCCAGCGCGGGCAACAGCGTCACGATGACGCTGTCGGACTGGGGTAAGCAGGTCACC
GTCACAAAGCCGGCGGTGTG

Downstream 100 bases:

>100_bases
GTCAGCAGCGCTCGATACCGGGCCGGAGCAGGCGGTGGCCCTCCCGGGCGTCGGGACGGCCGGGGAGCACGCCGCGCAGC
GGACCCCAGACGAGCGACCC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MQPTEVGPAIAPANSRSRRIAISAGSLAVLLGALDTYVVIAIIRDIMFDIGIAINQIQRVTPIITGYLLGYIAAMPLLGR
ASDRFGRKLVLQLSLAGFAIGSVVTALSNDLTPMVIGRFIQGVASGALLPVTLALAADLWATRNRASVLGGIGAAQELGS
VLGPLYGIAVVAALSTWRDVFWINVPLAAIAMVLIHFSLPARLKPERPEKVDVVGGVLLAIALGLSVIGLYNPAPDGKQI
LPDYGPPTLIGAVAAFVAFFVWERFARTRLIEPAGVHFRPFLAALGASLCAGAALMVTLVNVELFGQGVLGKDQTEAVLL
LLRFLIALPIGALLGGWLASRIGDRLVAFAGLMIAAGGYLLISKWPVDLLSARHDLGFVTLPVLDTDLVIAGIGLGLVIG
PLTSASLRVVPAAQHGIASAAVVVSRMIGMLIGLAALSAWGLYRLNQHLQTLPFPPGADTLAERLAAEADRYRAAYVLQY
GDIFIVTTIICVVGALLGLLISGRNEHADESPVPVGADHGDDAPTQFINVAGASGDADQTTRLPRQTPGRHRDEA

Sequences:

>Translated_555_residues
MQPTEVGPAIAPANSRSRRIAISAGSLAVLLGALDTYVVIAIIRDIMFDIGIAINQIQRVTPIITGYLLGYIAAMPLLGR
ASDRFGRKLVLQLSLAGFAIGSVVTALSNDLTPMVIGRFIQGVASGALLPVTLALAADLWATRNRASVLGGIGAAQELGS
VLGPLYGIAVVAALSTWRDVFWINVPLAAIAMVLIHFSLPARLKPERPEKVDVVGGVLLAIALGLSVIGLYNPAPDGKQI
LPDYGPPTLIGAVAAFVAFFVWERFARTRLIEPAGVHFRPFLAALGASLCAGAALMVTLVNVELFGQGVLGKDQTEAVLL
LLRFLIALPIGALLGGWLASRIGDRLVAFAGLMIAAGGYLLISKWPVDLLSARHDLGFVTLPVLDTDLVIAGIGLGLVIG
PLTSASLRVVPAAQHGIASAAVVVSRMIGMLIGLAALSAWGLYRLNQHLQTLPFPPGADTLAERLAAEADRYRAAYVLQY
GDIFIVTTIICVVGALLGLLISGRNEHADESPVPVGADHGDDAPTQFINVAGASGDADQTTRLPRQTPGRHRDEA
>Mature_555_residues
MQPTEVGPAIAPANSRSRRIAISAGSLAVLLGALDTYVVIAIIRDIMFDIGIAINQIQRVTPIITGYLLGYIAAMPLLGR
ASDRFGRKLVLQLSLAGFAIGSVVTALSNDLTPMVIGRFIQGVASGALLPVTLALAADLWATRNRASVLGGIGAAQELGS
VLGPLYGIAVVAALSTWRDVFWINVPLAAIAMVLIHFSLPARLKPERPEKVDVVGGVLLAIALGLSVIGLYNPAPDGKQI
LPDYGPPTLIGAVAAFVAFFVWERFARTRLIEPAGVHFRPFLAALGASLCAGAALMVTLVNVELFGQGVLGKDQTEAVLL
LLRFLIALPIGALLGGWLASRIGDRLVAFAGLMIAAGGYLLISKWPVDLLSARHDLGFVTLPVLDTDLVIAGIGLGLVIG
PLTSASLRVVPAAQHGIASAAVVVSRMIGMLIGLAALSAWGLYRLNQHLQTLPFPPGADTLAERLAAEADRYRAAYVLQY
GDIFIVTTIICVVGALLGLLISGRNEHADESPVPVGADHGDDAPTQFINVAGASGDADQTTRLPRQTPGRHRDEA

Specific function: Confers resistance to tetracycline and aminoglycosides such as streptomycin and gentamicin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=372, Percent_Identity=25, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789042, Length=458, Percent_Identity=24.6724890829694, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790195, Length=162, Percent_Identity=28.3950617283951, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788710, Length=440, Percent_Identity=23.4090909090909, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790146, Length=146, Percent_Identity=31.5068493150685, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325455, Length=177, Percent_Identity=26.5536723163842, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323735, Length=346, Percent_Identity=23.6994219653179, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319770, Length=413, Percent_Identity=24.2130750605327, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 58078; Mature: 58078

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPTEVGPAIAPANSRSRRIAISAGSLAVLLGALDTYVVIAIIRDIMFDIGIAINQIQRV
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPIITGYLLGYIAAMPLLGRASDRFGRKLVLQLSLAGFAIGSVVTALSNDLTPMVIGRFI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QGVASGALLPVTLALAADLWATRNRASVLGGIGAAQELGSVLGPLYGIAVVAALSTWRDV
HHHHCCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWINVPLAAIAMVLIHFSLPARLKPERPEKVDVVGGVLLAIALGLSVIGLYNPAPDGKQI
EEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LPDYGPPTLIGAVAAFVAFFVWERFARTRLIEPAGVHFRPFLAALGASLCAGAALMVTLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NVELFGQGVLGKDQTEAVLLLLRFLIALPIGALLGGWLASRIGDRLVAFAGLMIAAGGYL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LISKWPVDLLSARHDLGFVTLPVLDTDLVIAGIGLGLVIGPLTSASLRVVPAAQHGIASA
EEECCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHH
AVVVSRMIGMLIGLAALSAWGLYRLNQHLQTLPFPPGADTLAERLAAEADRYRAAYVLQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEEC
GDIFIVTTIICVVGALLGLLISGRNEHADESPVPVGADHGDDAPTQFINVAGASGDADQT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCCHHH
TRLPRQTPGRHRDEA
HCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPTEVGPAIAPANSRSRRIAISAGSLAVLLGALDTYVVIAIIRDIMFDIGIAINQIQRV
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPIITGYLLGYIAAMPLLGRASDRFGRKLVLQLSLAGFAIGSVVTALSNDLTPMVIGRFI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QGVASGALLPVTLALAADLWATRNRASVLGGIGAAQELGSVLGPLYGIAVVAALSTWRDV
HHHHCCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWINVPLAAIAMVLIHFSLPARLKPERPEKVDVVGGVLLAIALGLSVIGLYNPAPDGKQI
EEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LPDYGPPTLIGAVAAFVAFFVWERFARTRLIEPAGVHFRPFLAALGASLCAGAALMVTLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NVELFGQGVLGKDQTEAVLLLLRFLIALPIGALLGGWLASRIGDRLVAFAGLMIAAGGYL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LISKWPVDLLSARHDLGFVTLPVLDTDLVIAGIGLGLVIGPLTSASLRVVPAAQHGIASA
EEECCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHH
AVVVSRMIGMLIGLAALSAWGLYRLNQHLQTLPFPPGADTLAERLAAEADRYRAAYVLQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEEC
GDIFIVTTIICVVGALLGLLISGRNEHADESPVPVGADHGDDAPTQFINVAGASGDADQT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCCHHH
TRLPRQTPGRHRDEA
HCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]