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The map label for this gene is 119867999

Identifier: 119867999

GI number: 119867999

Start: 2079499

End: 2080737

Strand: Reverse

Name: 119867999

Synonym: Mkms_1962

Alternate gene names: NA

Gene position: 2080737-2079499 (Counterclockwise)

Preceding gene: 119868003

Following gene: 119867997

Centisome position: 36.27

GC content: 71.11

Gene sequence:

>1239_bases
ATGAGACGATGGTTCAAACATATGAGACATCCGTGTCACCATGGAGCCATGACCGCTCCGTCGATCGGCACCGTGCGCCG
TTGGTCGATGCTGGTGCTGGGCGTGATGTCCACGATGTGCGCGAACGTCTTCATCTACGGTGCGGCGTTCCTCATCCCGA
CCCTGCACACCGAGCGCGGTCTCGATCTCGCACTGGCCGGCCTGATGGCGTCGATGCCGAGCTTCGGCATGGTGGTCACG
CTGATCGCGTGGGGCTACGTCGTCGACCGGGTCGGCGAGCGTTTCGTGCTGACGGTCGGTTCGGCGCTCACCGCGGCGGC
CGCCTTTGCGGCCGCGGCGGTGGATTCCCTTCCGGCCGTGGGTGCCCTGCTGTTTCTCGGCGGAATGGCCGCCGCGGGCA
GCAATTCCGCGAGCGGGCGCCTGGTCGTCGGATGGTTCGCACCACACCAGCGCGGTCTGGTGATGGGGATCCGGCAGGCG
TCGGTTCCGCTCGGAGTCGGACTGGGGGCCTTGGTGATCCCCCGGGTCGCCCAGAGCCAGGGCGTCGCGGCGGCCCTGTT
GTTCCCGGCAGCCGTGTGCGCGGCGGCCGCGGTCCTCTGCTTGGTGGGTGTGCTCGATCCGCCGCGCCCACCGCGTGCGG
AGGCCGCCGCGGAGGTGCTGGCCAACCCGTACCGGGGCGATGCGGTGCTGTGGCGCATCCATGCCCTGTCCGTCCTGCTC
GTCGTGCCGCAGGCGGTGGTGTGGACGTTCACGCTCGTGTGGTTGATGTCCGAGCGGGGATGGTCGGCGGCGTCCGCGGG
CGCGCTGGTGACGCTCGCCCAGGTGCTCGGCGCGGGTGGCCGGATCGGCGCCGGCTACCTTTCCGACCGCGTCGGTGACC
GGTTGCGGCCCATTCGGTGGATCGCCTCGGCCGCGGCCGCGGTCCTGGCCCTGGTCGCGCTCACCGACGCGCTGGACTCC
CCGCTGAGTGTCGCGCTGATGGTGGCGGCATCGGTGATCACGGTCTCCGACAACGGTTTGGCGTTCACCGCCATCGCCGA
GATCGCGGGGCCGTTCTGGAGCGGACGGGCCCTGGGCGCGCAGAACACCAGCCAACACCTCGCCTCGGCGGCTTCGGCGC
CGGTCTTCGGCGGGCTGATCGGGGTGTTCGGATACCCCGCGGCGTTCGCGGTCCTGGCGGTGCTGCCGCTGCTGGCGCTA
CCCCTGGTGCCGGTGCACGCCCGGGTCGGGCGGCACTGA

Upstream 100 bases:

>100_bases
GGGGCCGGCATGGTCAGAGCGCCCACCAGCAGTGCCACTGCGCCAACAGTTCTCAACGTCACGCCGACACGGTACGCACC
GAATCGCCGTTGTCCACATC

Downstream 100 bases:

>100_bases
CTCACTCGCCCTCGAGGTTTGCGGCGCACGCCGCGAGGAGGCCACTCAGCCTGCGAGATTCGGCGCTGCTCAGCCCGGTC
AGCATCTGTGCCTCGACCGC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRRWFKHMRHPCHHGAMTAPSIGTVRRWSMLVLGVMSTMCANVFIYGAAFLIPTLHTERGLDLALAGLMASMPSFGMVVT
LIAWGYVVDRVGERFVLTVGSALTAAAAFAAAAVDSLPAVGALLFLGGMAAAGSNSASGRLVVGWFAPHQRGLVMGIRQA
SVPLGVGLGALVIPRVAQSQGVAAALLFPAAVCAAAAVLCLVGVLDPPRPPRAEAAAEVLANPYRGDAVLWRIHALSVLL
VVPQAVVWTFTLVWLMSERGWSAASAGALVTLAQVLGAGGRIGAGYLSDRVGDRLRPIRWIASAAAAVLALVALTDALDS
PLSVALMVAASVITVSDNGLAFTAIAEIAGPFWSGRALGAQNTSQHLASAASAPVFGGLIGVFGYPAAFAVLAVLPLLAL
PLVPVHARVGRH

Sequences:

>Translated_412_residues
MRRWFKHMRHPCHHGAMTAPSIGTVRRWSMLVLGVMSTMCANVFIYGAAFLIPTLHTERGLDLALAGLMASMPSFGMVVT
LIAWGYVVDRVGERFVLTVGSALTAAAAFAAAAVDSLPAVGALLFLGGMAAAGSNSASGRLVVGWFAPHQRGLVMGIRQA
SVPLGVGLGALVIPRVAQSQGVAAALLFPAAVCAAAAVLCLVGVLDPPRPPRAEAAAEVLANPYRGDAVLWRIHALSVLL
VVPQAVVWTFTLVWLMSERGWSAASAGALVTLAQVLGAGGRIGAGYLSDRVGDRLRPIRWIASAAAAVLALVALTDALDS
PLSVALMVAASVITVSDNGLAFTAIAEIAGPFWSGRALGAQNTSQHLASAASAPVFGGLIGVFGYPAAFAVLAVLPLLAL
PLVPVHARVGRH
>Mature_412_residues
MRRWFKHMRHPCHHGAMTAPSIGTVRRWSMLVLGVMSTMCANVFIYGAAFLIPTLHTERGLDLALAGLMASMPSFGMVVT
LIAWGYVVDRVGERFVLTVGSALTAAAAFAAAAVDSLPAVGALLFLGGMAAAGSNSASGRLVVGWFAPHQRGLVMGIRQA
SVPLGVGLGALVIPRVAQSQGVAAALLFPAAVCAAAAVLCLVGVLDPPRPPRAEAAAEVLANPYRGDAVLWRIHALSVLL
VVPQAVVWTFTLVWLMSERGWSAASAGALVTLAQVLGAGGRIGAGYLSDRVGDRLRPIRWIASAAAAVLALVALTDALDS
PLSVALMVAASVITVSDNGLAFTAIAEIAGPFWSGRALGAQNTSQHLASAASAPVFGGLIGVFGYPAAFAVLAVLPLLAL
PLVPVHARVGRH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI256219543, Length=260, Percent_Identity=25.7692307692308, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI256219598, Length=260, Percent_Identity=25.7692307692308, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4503847, Length=260, Percent_Identity=25.7692307692308, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI256219483, Length=260, Percent_Identity=25.7692307692308, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42355; Mature: 42355

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure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CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]