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The map label for this gene is kipR [H]

Identifier: 119868003

GI number: 119868003

Start: 2084668

End: 2085369

Strand: Reverse

Name: kipR [H]

Synonym: Mkms_1966

Alternate gene names: 119868003

Gene position: 2085369-2084668 (Counterclockwise)

Preceding gene: 119868007

Following gene: 119867999

Centisome position: 36.35

GC content: 75.36

Gene sequence:

>702_bases
GTGAGACAGGATAGCGGCATCGGCGTGCTGGACAAAGCGGTGGGCGTACTCCATACCGTGGCGGAGTCCCCCTGCGCCCT
GGCGGAACTGTGCGAGCGCACGGGACTCCCCCGGGCGACGGCGCACCGGTTGGCGGCGGGCCTGGAAACCCACCGGCTGC
TGGCCCGCGACGCCGACGGCCGGTGGCGGCTCGGCCCGGCGCTGACCGAACTGGCCGGCCAGGTCAACGATCCGCTGCTG
ACGGCCGGAGCGGTCATCCTGCCCCGGTTGCGCGAGATCACCGGCGAGAGCGTGCAGCTCTACCGGCGGGAGGGCACCGC
GCGGATCTGCATCGCCGCCCTCGAACCGCCCGCGGGACTGCGGGATACGGTGCCGGTCGGCACCCGGCTGCCGATGACGG
CGGGATCGGGTGCGAAGGTGCTGCTCGCCTACGCCGACCCCGCCACCCAGCAGGCCGTGCTGCCCGACGCGATGTTCACC
GAACGCACGCTGGCAGAGGTGCGCAGGCGCGGGTGGGCCCAGAGCGCGGCCGAACGCGAACCCGGGGTGGCCAGCGTCTC
CGCGCCGGTGCGCGACGGTCGAGGGGGCGTGGTGGCGGCGATCTCGGTGTCCGGCCCGATCGACCGGATGGGCCGCCGCC
CGGGCGCGCGGTGGGCCGCCGATCTGCTGGCCGCCGCCGACGCACTCGCCCGCCGGCTGTAA

Upstream 100 bases:

>100_bases
GCGCGGTGTGGCGGGCTGTGCCATTACCTTCTCGATTCTCGATACGCGGCCTGCGACGTTGCGCTGGCAATCTCACATTG
CGGGAGGATAGTATCTCCCT

Downstream 100 bases:

>100_bases
CCGCTCGGGCCGACCTGCCGAAAAAAGCGGCGCCCGACTCCGAAGAGCCGGGCGCCGCTGAGATGTACCCCCGATGGGAT
TCGAACCCACGCTACCGCCG

Product: regulatory proteins IclR

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRQDSGIGVLDKAVGVLHTVAESPCALAELCERTGLPRATAHRLAAGLETHRLLARDADGRWRLGPALTELAGQVNDPLL
TAGAVILPRLREITGESVQLYRREGTARICIAALEPPAGLRDTVPVGTRLPMTAGSGAKVLLAYADPATQQAVLPDAMFT
ERTLAEVRRRGWAQSAAEREPGVASVSAPVRDGRGGVVAAISVSGPIDRMGRRPGARWAADLLAAADALARRL

Sequences:

>Translated_233_residues
MRQDSGIGVLDKAVGVLHTVAESPCALAELCERTGLPRATAHRLAAGLETHRLLARDADGRWRLGPALTELAGQVNDPLL
TAGAVILPRLREITGESVQLYRREGTARICIAALEPPAGLRDTVPVGTRLPMTAGSGAKVLLAYADPATQQAVLPDAMFT
ERTLAEVRRRGWAQSAAEREPGVASVSAPVRDGRGGVVAAISVSGPIDRMGRRPGARWAADLLAAADALARRL
>Mature_233_residues
MRQDSGIGVLDKAVGVLHTVAESPCALAELCERTGLPRATAHRLAAGLETHRLLARDADGRWRLGPALTELAGQVNDPLL
TAGAVILPRLREITGESVQLYRREGTARICIAALEPPAGLRDTVPVGTRLPMTAGSGAKVLLAYADPATQQAVLPDAMFT
ERTLAEVRRRGWAQSAAEREPGVASVSAPVRDGRGGVVAAISVSGPIDRMGRRPGARWAADLLAAADALARRL

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789999, Length=231, Percent_Identity=29.4372294372294, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788131, Length=247, Percent_Identity=25.5060728744939, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786715, Length=223, Percent_Identity=26.0089686098655, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082359, Length=237, Percent_Identity=27.0042194092827, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788581, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786468, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 24495; Mature: 24495

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQDSGIGVLDKAVGVLHTVAESPCALAELCERTGLPRATAHRLAAGLETHRLLARDADG
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
RWRLGPALTELAGQVNDPLLTAGAVILPRLREITGESVQLYRREGTARICIAALEPPAGL
CEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEEECCCCCC
RDTVPVGTRLPMTAGSGAKVLLAYADPATQQAVLPDAMFTERTLAEVRRRGWAQSAAERE
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
PGVASVSAPVRDGRGGVVAAISVSGPIDRMGRRPGARWAADLLAAADALARRL
CCCEECCCCCCCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRQDSGIGVLDKAVGVLHTVAESPCALAELCERTGLPRATAHRLAAGLETHRLLARDADG
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
RWRLGPALTELAGQVNDPLLTAGAVILPRLREITGESVQLYRREGTARICIAALEPPAGL
CEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEEECCCCCC
RDTVPVGTRLPMTAGSGAKVLLAYADPATQQAVLPDAMFTERTLAEVRRRGWAQSAAERE
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
PGVASVSAPVRDGRGGVVAAISVSGPIDRMGRRPGARWAADLLAAADALARRL
CCCEECCCCCCCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]