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The map label for this gene is 119867763

Identifier: 119867763

GI number: 119867763

Start: 1838979

End: 1839983

Strand: Reverse

Name: 119867763

Synonym: Mkms_1723

Alternate gene names: NA

Gene position: 1839983-1838979 (Counterclockwise)

Preceding gene: 119867764

Following gene: 119867698

Centisome position: 32.07

GC content: 62.99

Gene sequence:

>1005_bases
ATGCGCGTCCTGATCCTGGGCGCTGGTGGGCTCGGATCTGTCTTGGGCGGATATTTGGCGAACATTGGCGTCGATGTCAC
CCTGGTCGGCAGGCCGGCGCACGCCGAGGCCATCACGCGCTACGGTCTCCGAATCACGGGCCGTCGGGGCGACCTGGTGA
TTACTGATAACTTGACGGCGGTCGACCAGACAGCCAAAGCCACGGGGCATTTCGATTACCTGGTGTTGGCGGTGAAGGGC
AAAGATACCGCGCAGGCCCTGGCGGAGGCCGACGGGTTGCGTGATTGCGTGAGCAGCGCGTTGTCGGTGCAGAACACCGT
CGAGAAGGATGCGACGCTCGCCGGGTGGCTTGGGCCCGACAGGGTGATCGGAGCCTCCACCATCGAGGGCGGCACCTTGC
TCGAACCGGGGCTCGTCAGAAATCACCTTACAGCTGAGGTGACCGCTTACTTCGGCGAACTTGACGGGACATCTAGTGCG
CGCGTCGACGACTTGACGGCTGCCTTCACCAACGCCGGCCTTCCTGCAAAGGCGGTAGGCAACATCGAGCAGGTCGAGTG
GGAAAAGCTCGCCCAGATCGCGTTGGCGGCCGCGTGGTCGGTCACGGCGCTGGGCGCAATCCCTGACGCCTCGGTCTTCG
AGGGCATGGAGGTGCGCGAGGGAGCGATGTACTTCGTCGCGCTGGCAAAGGACCTTCTTGGGGTCTACCGGGCGAAGGGC
TACGAGCCGATGAACTTCTTTGCGCCTCTCTCCCGCCTGAAGGAACTCGATGCCCTTCCGACGGCCGACGCGATCGAGTT
TGTCATCGGGCAAGGCAGAGTAATGCGCGAGAAGGGAAACCTGGGACACCCCTCGATGTACGAGGATGTTCTGCGACGAC
GTAAGACCGAGGTCGACTTCATGCTGGCGCCTTATCTCGCCGCCGCTCAAGAACTGGGCATGGATGTACCGACGCTGCGG
GTCGCCTACCAGATCATCAAGACCGTCGACCGATTCCTGGCCTAG

Upstream 100 bases:

>100_bases
GGCTGCGTGCCGGCCCGGTGCGACCGCCCGTCAAGGCCCGGCTGTCTGCTCCGGAGCGGGAAGTCCTGCAGGAGAAACTG
ACGGCCGCCGAGGCCATTTG

Downstream 100 bases:

>100_bases
CAATGACGCGGTTCGAAGGCGATGTTCAGGTAGCGCGCAAGGTGTGTTGGGGAGTGACGCCGAACTTGCGCCGATACTCC
GCGCTGAAGCGGCCCAGATG

Product: ketopantoate reductase ApbA/PanE

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRVLILGAGGLGSVLGGYLANIGVDVTLVGRPAHAEAITRYGLRITGRRGDLVITDNLTAVDQTAKATGHFDYLVLAVKG
KDTAQALAEADGLRDCVSSALSVQNTVEKDATLAGWLGPDRVIGASTIEGGTLLEPGLVRNHLTAEVTAYFGELDGTSSA
RVDDLTAAFTNAGLPAKAVGNIEQVEWEKLAQIALAAAWSVTALGAIPDASVFEGMEVREGAMYFVALAKDLLGVYRAKG
YEPMNFFAPLSRLKELDALPTADAIEFVIGQGRVMREKGNLGHPSMYEDVLRRRKTEVDFMLAPYLAAAQELGMDVPTLR
VAYQIIKTVDRFLA

Sequences:

>Translated_334_residues
MRVLILGAGGLGSVLGGYLANIGVDVTLVGRPAHAEAITRYGLRITGRRGDLVITDNLTAVDQTAKATGHFDYLVLAVKG
KDTAQALAEADGLRDCVSSALSVQNTVEKDATLAGWLGPDRVIGASTIEGGTLLEPGLVRNHLTAEVTAYFGELDGTSSA
RVDDLTAAFTNAGLPAKAVGNIEQVEWEKLAQIALAAAWSVTALGAIPDASVFEGMEVREGAMYFVALAKDLLGVYRAKG
YEPMNFFAPLSRLKELDALPTADAIEFVIGQGRVMREKGNLGHPSMYEDVLRRRKTEVDFMLAPYLAAAQELGMDVPTLR
VAYQIIKTVDRFLA
>Mature_334_residues
MRVLILGAGGLGSVLGGYLANIGVDVTLVGRPAHAEAITRYGLRITGRRGDLVITDNLTAVDQTAKATGHFDYLVLAVKG
KDTAQALAEADGLRDCVSSALSVQNTVEKDATLAGWLGPDRVIGASTIEGGTLLEPGLVRNHLTAEVTAYFGELDGTSSA
RVDDLTAAFTNAGLPAKAVGNIEQVEWEKLAQIALAAAWSVTALGAIPDASVFEGMEVREGAMYFVALAKDLLGVYRAKG
YEPMNFFAPLSRLKELDALPTADAIEFVIGQGRVMREKGNLGHPSMYEDVLRRRKTEVDFMLAPYLAAAQELGMDVPTLR
VAYQIIKTVDRFLA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 35596; Mature: 35596

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLILGAGGLGSVLGGYLANIGVDVTLVGRPAHAEAITRYGLRITGRRGDLVITDNLTA
CEEEEEECCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEECCCCCEEEECCCHH
VDQTAKATGHFDYLVLAVKGKDTAQALAEADGLRDCVSSALSVQNTVEKDATLAGWLGPD
HHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
RVIGASTIEGGTLLEPGLVRNHLTAEVTAYFGELDGTSSARVDDLTAAFTNAGLPAKAVG
CEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHC
NIEQVEWEKLAQIALAAAWSVTALGAIPDASVFEGMEVREGAMYFVALAKDLLGVYRAKG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCC
YEPMNFFAPLSRLKELDALPTADAIEFVIGQGRVMREKGNLGHPSMYEDVLRRRKTEVDF
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCHH
MLAPYLAAAQELGMDVPTLRVAYQIIKTVDRFLA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRVLILGAGGLGSVLGGYLANIGVDVTLVGRPAHAEAITRYGLRITGRRGDLVITDNLTA
CEEEEEECCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEECCCCCEEEECCCHH
VDQTAKATGHFDYLVLAVKGKDTAQALAEADGLRDCVSSALSVQNTVEKDATLAGWLGPD
HHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
RVIGASTIEGGTLLEPGLVRNHLTAEVTAYFGELDGTSSARVDDLTAAFTNAGLPAKAVG
CEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHC
NIEQVEWEKLAQIALAAAWSVTALGAIPDASVFEGMEVREGAMYFVALAKDLLGVYRAKG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCC
YEPMNFFAPLSRLKELDALPTADAIEFVIGQGRVMREKGNLGHPSMYEDVLRRRKTEVDF
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCHH
MLAPYLAAAQELGMDVPTLRVAYQIIKTVDRFLA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]