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The map label for this gene is yngJ [H]

Identifier: 119867672

GI number: 119867672

Start: 1741884

End: 1743098

Strand: Reverse

Name: yngJ [H]

Synonym: Mkms_1627

Alternate gene names: 119867672

Gene position: 1743098-1741884 (Counterclockwise)

Preceding gene: 119867673

Following gene: 119867666

Centisome position: 30.38

GC content: 66.42

Gene sequence:

>1215_bases
ATGGCAATCAACCTGGAACTGCCGAAGAAGCTGCACGCGGTCATCGAGAAGGCCCACCAGGGCGCCGCGGAGATGCTGCG
GCCGATCTCGCGCAAATACGACCTCAGAGAGCACGACTACCCCGTCGAGCTGGACACCTTGGCCACCCTGTTCGAGGGCA
TCTCCGAGGCCAACACCATCTCGTTCGCGGGCGCCGAGGCGTTCCGCGACGCCGAGGACGGCCCCAAGGGGAACGTCAAC
GGCGGCAACATGTCCGCGGTCCTCAACGTCACCGAGATCAGCTGGGGTGATGTGGGGCTGATGCTGTCGGTGCCCCGGCA
GGGCCTGGGCAACGCGGCGATCTCCGGGGTCGCGACCGACGAACAGCTCGAACGGCTCGGCAAGGGTGTGTGGGCCGCCA
TGGCCATCACCGAACCGGGTTTCGGTTCGGACTCCGCGGCGGTGTCGACCACGGCCCGGCTCGAGGGCGACGAATACGTC
ATCAACGGCGAGAAGATCTTCGTCACCGCGGGTTCACGTGCCACCCACATCGTCGTCTGGGCCACCCTGGACAAGTCGCT
GGGACGGGCGGCGATCAAATCGTTCATCGTCCCGCGTGACCATCCCGGTGTGACGGTCGAGCGGCTCGAGGACAAGCTGG
GCATCAAGGCCTCCGACACCGCGGTGATCCGCTTCGACAACGCCCGCATCCCGAAGGACAACCTCCTCGGCGACCCGGAG
ATCCACGTCGAAAAGGGTTTCGCCGGGGTCATGGAGACCTTCGACAACACCCGGCCGGTGGTGGCGGGGATGGCCGTCGG
CATCGGACGCGCCGCGCTCGAGGAGCTCCGCAAGATCCTGACCGACGCCGGCGTCGAGATCTCCTACGACAAACCCGCCC
ACGCCCAGAGCGCCGCGGCAGCGGAATTCCTTCGGCTCGAGGCGGATTGGGAGGCGGGTTATCTGCTGACCGTGCGCTCG
GCATGGCAGGCCGACAACGCCATCCCGAACTCCAAGGAGGCGTCGATGGCCAAGGCCAAGGCGGCCCGGGTGGGCAGCGA
CATCACCTTGAAGGTGGTCGAGATGGCAGGCACCGTCGGCTATTCCGAGGAGAGCCTGCTGGAGAAGTGGGCGCGCGACA
GCAAGATCCTCGACATCTTCGAGGGCACTCAGCAGATTCAGCAGCTCGTGGTGGCCCGCCGCCTGCTCGGCCTCACGTCG
GCACAACTGAAGTAG

Upstream 100 bases:

>100_bases
TACACCAAGGAACACCCCGTCGAACGCTGGTACCGCGATCTACGCGTGATCGGCGTCGCCGAGGGCGTCGTGGTCCTCTA
AGTCAGAAACGGATCCTGTC

Downstream 100 bases:

>100_bases
CCGTTCACATTTCGAGTAGCTGCTGGCCCAGGTAACCTCCTTCGGGTGCGCCAGGCGGAATCGCGAACACCGCCGATCCG
ACGGGCGTGATCCACGGGTT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MAINLELPKKLHAVIEKAHQGAAEMLRPISRKYDLREHDYPVELDTLATLFEGISEANTISFAGAEAFRDAEDGPKGNVN
GGNMSAVLNVTEISWGDVGLMLSVPRQGLGNAAISGVATDEQLERLGKGVWAAMAITEPGFGSDSAAVSTTARLEGDEYV
INGEKIFVTAGSRATHIVVWATLDKSLGRAAIKSFIVPRDHPGVTVERLEDKLGIKASDTAVIRFDNARIPKDNLLGDPE
IHVEKGFAGVMETFDNTRPVVAGMAVGIGRAALEELRKILTDAGVEISYDKPAHAQSAAAAEFLRLEADWEAGYLLTVRS
AWQADNAIPNSKEASMAKAKAARVGSDITLKVVEMAGTVGYSEESLLEKWARDSKILDIFEGTQQIQQLVVARRLLGLTS
AQLK

Sequences:

>Translated_404_residues
MAINLELPKKLHAVIEKAHQGAAEMLRPISRKYDLREHDYPVELDTLATLFEGISEANTISFAGAEAFRDAEDGPKGNVN
GGNMSAVLNVTEISWGDVGLMLSVPRQGLGNAAISGVATDEQLERLGKGVWAAMAITEPGFGSDSAAVSTTARLEGDEYV
INGEKIFVTAGSRATHIVVWATLDKSLGRAAIKSFIVPRDHPGVTVERLEDKLGIKASDTAVIRFDNARIPKDNLLGDPE
IHVEKGFAGVMETFDNTRPVVAGMAVGIGRAALEELRKILTDAGVEISYDKPAHAQSAAAAEFLRLEADWEAGYLLTVRS
AWQADNAIPNSKEASMAKAKAARVGSDITLKVVEMAGTVGYSEESLLEKWARDSKILDIFEGTQQIQQLVVARRLLGLTS
AQLK
>Mature_403_residues
AINLELPKKLHAVIEKAHQGAAEMLRPISRKYDLREHDYPVELDTLATLFEGISEANTISFAGAEAFRDAEDGPKGNVNG
GNMSAVLNVTEISWGDVGLMLSVPRQGLGNAAISGVATDEQLERLGKGVWAAMAITEPGFGSDSAAVSTTARLEGDEYVI
NGEKIFVTAGSRATHIVVWATLDKSLGRAAIKSFIVPRDHPGVTVERLEDKLGIKASDTAVIRFDNARIPKDNLLGDPEI
HVEKGFAGVMETFDNTRPVVAGMAVGIGRAALEELRKILTDAGVEISYDKPAHAQSAAAAEFLRLEADWEAGYLLTVRSA
WQADNAIPNSKEASMAKAKAARVGSDITLKVVEMAGTVGYSEESLLEKWARDSKILDIFEGTQQIQQLVVARRLLGLTSA
QLK

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=410, Percent_Identity=32.4390243902439, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI187960098, Length=402, Percent_Identity=31.3432835820896, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI4557231, Length=402, Percent_Identity=31.3432835820896, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4501859, Length=328, Percent_Identity=30.1829268292683, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI21361497, Length=319, Percent_Identity=31.0344827586207, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226958414, Length=280, Percent_Identity=28.9285714285714, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226958412, Length=280, Percent_Identity=28.9285714285714, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4557235, Length=395, Percent_Identity=27.5949367088608, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI76496475, Length=395, Percent_Identity=27.5949367088608, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4501857, Length=336, Percent_Identity=25.5952380952381, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI7656849, Length=275, Percent_Identity=25.8181818181818, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4503943, Length=297, Percent_Identity=24.9158249158249, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7669494, Length=285, Percent_Identity=24.2105263157895, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786223, Length=284, Percent_Identity=26.056338028169, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081958, Length=265, Percent_Identity=25.2830188679245, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=402, Percent_Identity=30.5970149253731, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17569725, Length=327, Percent_Identity=35.1681957186544, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17570075, Length=318, Percent_Identity=34.2767295597484, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17508101, Length=317, Percent_Identity=33.1230283911672, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17506239, Length=283, Percent_Identity=32.8621908127208, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=27.2357723577236, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71990804, Length=268, Percent_Identity=29.8507462686567, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17538396, Length=270, Percent_Identity=27.7777777777778, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=343, Percent_Identity=29.7376093294461, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=161, Percent_Identity=35.4037267080745, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17533517, Length=272, Percent_Identity=25.7352941176471, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17505929, Length=268, Percent_Identity=26.865671641791, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=271, Percent_Identity=25.4612546125461, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=156, Percent_Identity=29.4871794871795, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=209, Percent_Identity=33.4928229665072, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534353, Length=269, Percent_Identity=23.4200743494424, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=326, Percent_Identity=36.5030674846626, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21356377, Length=274, Percent_Identity=36.8613138686131, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24646207, Length=397, Percent_Identity=29.2191435768262, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24666513, Length=385, Percent_Identity=30.6493506493506, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281363737, Length=341, Percent_Identity=26.9794721407625, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355753, Length=275, Percent_Identity=28.7272727272727, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19920834, Length=300, Percent_Identity=26, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43389; Mature: 43258

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINLELPKKLHAVIEKAHQGAAEMLRPISRKYDLREHDYPVELDTLATLFEGISEANTI
CEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEE
SFAGAEAFRDAEDGPKGNVNGGNMSAVLNVTEISWGDVGLMLSVPRQGLGNAAISGVATD
EECCHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCH
EQLERLGKGVWAAMAITEPGFGSDSAAVSTTARLEGDEYVINGEKIFVTAGSRATHIVVW
HHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCCEEEECCCEEEEEECCCCEEEEEE
ATLDKSLGRAAIKSFIVPRDHPGVTVERLEDKLGIKASDTAVIRFDNARIPKDNLLGDPE
EECCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCCCC
IHVEKGFAGVMETFDNTRPVVAGMAVGIGRAALEELRKILTDAGVEISYDKPAHAQSAAA
EEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHH
AEFLRLEADWEAGYLLTVRSAWQADNAIPNSKEASMAKAKAARVGSDITLKVVEMAGTVG
HHHHEEECCCCCCEEEEEECHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHCCCC
YSEESLLEKWARDSKILDIFEGTQQIQQLVVARRLLGLTSAQLK
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
AINLELPKKLHAVIEKAHQGAAEMLRPISRKYDLREHDYPVELDTLATLFEGISEANTI
EEECCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEE
SFAGAEAFRDAEDGPKGNVNGGNMSAVLNVTEISWGDVGLMLSVPRQGLGNAAISGVATD
EECCHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCH
EQLERLGKGVWAAMAITEPGFGSDSAAVSTTARLEGDEYVINGEKIFVTAGSRATHIVVW
HHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCCEEEECCCEEEEEECCCCEEEEEE
ATLDKSLGRAAIKSFIVPRDHPGVTVERLEDKLGIKASDTAVIRFDNARIPKDNLLGDPE
EECCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCCCC
IHVEKGFAGVMETFDNTRPVVAGMAVGIGRAALEELRKILTDAGVEISYDKPAHAQSAAA
EEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHH
AEFLRLEADWEAGYLLTVRSAWQADNAIPNSKEASMAKAKAARVGSDITLKVVEMAGTVG
HHHHEEECCCCCCEEEEEECHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHCCCC
YSEESLLEKWARDSKILDIFEGTQQIQQLVVARRLLGLTSAQLK
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]