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The map label for this gene is acdA [H]

Identifier: 119867673

GI number: 119867673

Start: 1743118

End: 1744521

Strand: Reverse

Name: acdA [H]

Synonym: Mkms_1628

Alternate gene names: 119867673

Gene position: 1744521-1743118 (Counterclockwise)

Preceding gene: 119867674

Following gene: 119867672

Centisome position: 30.41

GC content: 70.3

Gene sequence:

>1404_bases
ATGACCAACACCCTGCCGTCCAAGAACGGCACCTCAGCCCGTCCCAAGCGCGCCGGCAAAGAGAGCGCGGTCGGCCTGCA
GCGGCACAAGCGGACGCCGACCGACATCGGCCTGGCGCTGATCACCCCGCTGGTGGGCCAGGAATTCCTCGACCGCTACA
ACCTGCGGGATCCCCTCAACCGGGGACTCAAGTACGGCGTCAAGCAGGTGTTCTCGGCAGCGGGCGCCTCGACCCGGCAG
TTCAAGCGGATCCAGGGCCTCGGAAAGCCGCCCACCCGCCTGACGAGCGCGCCGAAGGGGTCGGACTACTTCGACCTGAC
CCCCGACGACGACCAGAAGATGATCGTCGAGACCGTCAAGGAGTTCGCCGAGGAAGTCCTGCGCCCGGCCGCCCACGACG
CCGACGCCGCGGCCACCTACCCGCCGGACCTGATTGCCAAGGCCGCCGAACTGGGCATCACGGCGGTCAACATCCCCGAA
GACTTCGAGGGCATCGCCGAACACCGCTCGACGATCACCAACGCGCTGGTGGCCGAGGCGCTCGCCTACGGCGACATGGG
TCTGGCCCTGCCGATCCTCGCCCCCGGCGGCGTGGCGGCGGCGCTCACCCACTGGGGCAGCGCCGACCAGCAGGCCACCT
ACCTGCCCGCCTTCGCAGGCGAGAACGTGCCGCAGGCCTGTGTGGCGATCGCCGAACCGCGCCCGCTGTTCGACCCGACC
GCGCTCAAGACCACCGCGGTCCGCACTCCGGGCGGCTACCGGCTGACCGGAACCAAGTCGCTGGTTCCCGCCGCCGCGGA
CGCGGAGGTCTTCATCGTCGCGGCGCAGCTCGACGGCAAGCCCGCACTGTTCATCGTCGAATCGGCCTCCAAGGGGCTGA
CCGTCACCCCCGACCCCAGCATGGGCGTGCGCGCGGCCGCGCTGGGCCGGGTGGAGCTCGACAACGTGGCGGTGCCGCTG
GGCAACCGGCTCGGCGAGGACGGCGCAACGGACGAGGACTACCGCGAGGCGATCGCGCTGTCGCGGCTCGGCTGGGCGGC
ACTGGCAGTCGGCACGTCACACGCGGTGCTCGACTACGTGGTGCCCTACGTCAAGGAGCGGGAGGCGTTCGGCGAGCCGA
TCGCTCACCGTCAGGCGGTGGCGTTCATGTGCGCCAACATCGCCATCGAACTCGACGGGCTGCGCCTCATCACCTGGCGG
GGCGCATCGCGTGCCGAACAGGGTCTGCCCTACGCCCGGGAGGCCGCGCTCGCCAAGCGACTCGGCACGGACAAGGGCAT
GCAAATCGGCCTCGACGGCGTCCAGCTGCTCGGCGGTCACGGCTACACCAAGGAACACCCCGTCGAACGCTGGTACCGCG
ATCTACGCGTGATCGGCGTCGCCGAGGGCGTCGTGGTCCTCTAA

Upstream 100 bases:

>100_bases
CTTCGGTGAACAGGTGTGAACTAACTAACACGCCGCGCCGACCTTACTCCGGAGTAAGATACGGTCATGGCCATCGCCCC
GACCAAGTGAGGCAGCTGGA

Downstream 100 bases:

>100_bases
GTCAGAAACGGATCCTGTCATGGCAATCAACCTGGAACTGCCGAAGAAGCTGCACGCGGTCATCGAGAAGGCCCACCAGG
GCGCCGCGGAGATGCTGCGG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTNTLPSKNGTSARPKRAGKESAVGLQRHKRTPTDIGLALITPLVGQEFLDRYNLRDPLNRGLKYGVKQVFSAAGASTRQ
FKRIQGLGKPPTRLTSAPKGSDYFDLTPDDDQKMIVETVKEFAEEVLRPAAHDADAAATYPPDLIAKAAELGITAVNIPE
DFEGIAEHRSTITNALVAEALAYGDMGLALPILAPGGVAAALTHWGSADQQATYLPAFAGENVPQACVAIAEPRPLFDPT
ALKTTAVRTPGGYRLTGTKSLVPAAADAEVFIVAAQLDGKPALFIVESASKGLTVTPDPSMGVRAAALGRVELDNVAVPL
GNRLGEDGATDEDYREAIALSRLGWAALAVGTSHAVLDYVVPYVKEREAFGEPIAHRQAVAFMCANIAIELDGLRLITWR
GASRAEQGLPYAREAALAKRLGTDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRVIGVAEGVVVL

Sequences:

>Translated_467_residues
MTNTLPSKNGTSARPKRAGKESAVGLQRHKRTPTDIGLALITPLVGQEFLDRYNLRDPLNRGLKYGVKQVFSAAGASTRQ
FKRIQGLGKPPTRLTSAPKGSDYFDLTPDDDQKMIVETVKEFAEEVLRPAAHDADAAATYPPDLIAKAAELGITAVNIPE
DFEGIAEHRSTITNALVAEALAYGDMGLALPILAPGGVAAALTHWGSADQQATYLPAFAGENVPQACVAIAEPRPLFDPT
ALKTTAVRTPGGYRLTGTKSLVPAAADAEVFIVAAQLDGKPALFIVESASKGLTVTPDPSMGVRAAALGRVELDNVAVPL
GNRLGEDGATDEDYREAIALSRLGWAALAVGTSHAVLDYVVPYVKEREAFGEPIAHRQAVAFMCANIAIELDGLRLITWR
GASRAEQGLPYAREAALAKRLGTDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRVIGVAEGVVVL
>Mature_466_residues
TNTLPSKNGTSARPKRAGKESAVGLQRHKRTPTDIGLALITPLVGQEFLDRYNLRDPLNRGLKYGVKQVFSAAGASTRQF
KRIQGLGKPPTRLTSAPKGSDYFDLTPDDDQKMIVETVKEFAEEVLRPAAHDADAAATYPPDLIAKAAELGITAVNIPED
FEGIAEHRSTITNALVAEALAYGDMGLALPILAPGGVAAALTHWGSADQQATYLPAFAGENVPQACVAIAEPRPLFDPTA
LKTTAVRTPGGYRLTGTKSLVPAAADAEVFIVAAQLDGKPALFIVESASKGLTVTPDPSMGVRAAALGRVELDNVAVPLG
NRLGEDGATDEDYREAIALSRLGWAALAVGTSHAVLDYVVPYVKEREAFGEPIAHRQAVAFMCANIAIELDGLRLITWRG
ASRAEQGLPYAREAALAKRLGTDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRVIGVAEGVVVL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=367, Percent_Identity=30.7901907356948, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI4557233, Length=369, Percent_Identity=29.2682926829268, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI187960098, Length=371, Percent_Identity=29.9191374663073, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4557231, Length=371, Percent_Identity=29.9191374663073, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7656849, Length=363, Percent_Identity=26.4462809917355, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI226958412, Length=366, Percent_Identity=25.9562841530055, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI4557235, Length=367, Percent_Identity=28.0653950953678, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI76496475, Length=367, Percent_Identity=28.0653950953678, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI226958414, Length=324, Percent_Identity=26.8518518518519, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4501857, Length=361, Percent_Identity=25.7617728531856, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI21361497, Length=368, Percent_Identity=25.2717391304348, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4503943, Length=361, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI7669494, Length=362, Percent_Identity=26.2430939226519, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI87081958, Length=366, Percent_Identity=27.3224043715847, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1786223, Length=368, Percent_Identity=26.6304347826087, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17569725, Length=387, Percent_Identity=32.0413436692506, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17534899, Length=369, Percent_Identity=32.7913279132791, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17506239, Length=362, Percent_Identity=29.5580110497238, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=361, Percent_Identity=29.3628808864266, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17570075, Length=369, Percent_Identity=29.810298102981, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17533517, Length=362, Percent_Identity=24.3093922651934, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71990804, Length=298, Percent_Identity=28.1879194630872, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=398, Percent_Identity=25.3768844221106, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=379, Percent_Identity=27.4406332453826, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=23.6220472440945, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=29.1845493562232, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=27.4074074074074, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=389, Percent_Identity=22.879177377892, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=336, Percent_Identity=26.7857142857143, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531909, Length=228, Percent_Identity=25.8771929824561, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=22.7272727272727, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666513, Length=366, Percent_Identity=31.1475409836066, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21356377, Length=369, Percent_Identity=30.8943089430894, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=32.6259946949602, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24646207, Length=362, Percent_Identity=29.8342541436464, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI281363737, Length=369, Percent_Identity=25.4742547425474, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21355753, Length=368, Percent_Identity=25.5434782608696, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19920834, Length=367, Percent_Identity=24.7956403269755, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 49638; Mature: 49507

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTLPSKNGTSARPKRAGKESAVGLQRHKRTPTDIGLALITPLVGQEFLDRYNLRDPLN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
RGLKYGVKQVFSAAGASTRQFKRIQGLGKPPTRLTSAPKGSDYFDLTPDDDQKMIVETVK
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCCCCCCCCEECCCCCCCHHHHHHHHH
EFAEEVLRPAAHDADAAATYPPDLIAKAAELGITAVNIPEDFEGIAEHRSTITNALVAEA
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LAYGDMGLALPILAPGGVAAALTHWGSADQQATYLPAFAGENVPQACVAIAEPRPLFDPT
HHHCCCCCEEEEECCCCHHHHHHHCCCCCCCCEECCHHCCCCCCHHHHEECCCCCCCCCC
ALKTTAVRTPGGYRLTGTKSLVPAAADAEVFIVAAQLDGKPALFIVESASKGLTVTPDPS
CCCEEEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCEECCCCC
MGVRAAALGRVELDNVAVPLGNRLGEDGATDEDYREAIALSRLGWAALAVGTSHAVLDYV
CCCHHHHHCCEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCHHHHHHHH
VPYVKEREAFGEPIAHRQAVAFMCANIAIELDGLRLITWRGASRAEQGLPYAREAALAKR
HHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCEEEEEECCCCHHHHCCCHHHHHHHHHH
LGTDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRVIGVAEGVVVL
HCCCCCCEECCCHHHEECCCCCCCCCHHHHHHHHHEEEEECCCEEEC
>Mature Secondary Structure 
TNTLPSKNGTSARPKRAGKESAVGLQRHKRTPTDIGLALITPLVGQEFLDRYNLRDPLN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
RGLKYGVKQVFSAAGASTRQFKRIQGLGKPPTRLTSAPKGSDYFDLTPDDDQKMIVETVK
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCCCCCCCCEECCCCCCCHHHHHHHHH
EFAEEVLRPAAHDADAAATYPPDLIAKAAELGITAVNIPEDFEGIAEHRSTITNALVAEA
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LAYGDMGLALPILAPGGVAAALTHWGSADQQATYLPAFAGENVPQACVAIAEPRPLFDPT
HHHCCCCCEEEEECCCCHHHHHHHCCCCCCCCEECCHHCCCCCCHHHHEECCCCCCCCCC
ALKTTAVRTPGGYRLTGTKSLVPAAADAEVFIVAAQLDGKPALFIVESASKGLTVTPDPS
CCCEEEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCEECCCCC
MGVRAAALGRVELDNVAVPLGNRLGEDGATDEDYREAIALSRLGWAALAVGTSHAVLDYV
CCCHHHHHCCEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCHHHHHHHH
VPYVKEREAFGEPIAHRQAVAFMCANIAIELDGLRLITWRGASRAEQGLPYAREAALAKR
HHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCEEEEEECCCCHHHHCCCHHHHHHHHHH
LGTDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRVIGVAEGVVVL
HCCCCCCEECCCHHHEECCCCCCCCCHHHHHHHHHEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]