| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is mrcB [H]
Identifier: 119867553
GI number: 119867553
Start: 1618612
End: 1621107
Strand: Reverse
Name: mrcB [H]
Synonym: Mkms_1505
Alternate gene names: 119867553
Gene position: 1621107-1618612 (Counterclockwise)
Preceding gene: 119867557
Following gene: 119867552
Centisome position: 28.26
GC content: 67.47
Gene sequence:
>2496_bases ATGCGCGACAAGCGTCGGGCAAAGTGGCAAGCGCTCGCCAGACTGGCGGGCTGCTGCCTCGTCGCCGGGCTGCTCGCTGC GGCGTTGATGTTCCCGTTCGTCGGGGGCGCCGGGTCGGCGATCATGCGCGTATCCGACTCGGCCACTGAAGAATCCACGC AGCTGATCGAGGGTGAGGTGCCGATCGTGTCCACCATGGTGGACACCGAAGGAAACCCCATCGCATGGCTGTACGAGCAG CGCCGCTGGGAGGTACCCAGCAACCGGATCGCCAACACGATGAAGCTGGCGATCATCTCTATCGAGGACAAGCGTTTCAG TGAGCACAACGGCGTCGATTGGCAGGGCACCCTGACCGGCCTGGCAGGTTATCTGCAGGGCGCCGAAAGAACCCGGGGCG GGTCGACGCTCGAGCAGCAGTACGTCAAGAACTTCAACCTCCTGGTGAAGGCGCAGACCGATGCGGACCGGCGCGCCGCG GTGGAGAACACCCCGGCACGCAAGCTCCGCGAGATCCGGGCGGCCCTGGCCATGGACGCGGCGCTGCCCAAGGCGGAGAT CCTGGCCCGCTACTTGAACCTGGTGTCGTTCGGCAACGGTGCGTTCGGCGTTCAGGACGCCGCGAAGACCTACTTCGGCA TCAACGCGAGCGAGCTCAACTGGCAGCAGGCGGCAATGCTGGCCGGAATGGTGCGCTCCCCCAGCTCGCTGGACCCGTAC ACCCACCCCGATGCCACGCTGGAACGGCGCAACGTGGTGCTCAACACCATCATCGAAAACCTGCCCGACAAGGCCGACGA ACTCCGCGCCGCCAAGGACCGGCCGCTGGGCGTGCTGCCGCGGCCCGATCCGCTGCCGCAGGGCTGCATCGCGGCCCGCG ACCGCGCGTTCTTCTGTGCGTACGCGATGGAGTACCTGGCCCGCGCGGGTCTGAGCAAGGAGGACGTGGCCCGCAACGGC TATCTGATCCGCACCACCCTCGACCCCAAGGTCCAGGACAGCGTGAAGAACGCCATCGACGAAGTCGCCGACCCCACCGC GGTCGGCGTCGCCAGCGTGATGAGCGTGATCAGGCCCGGCAAGGACGCCCACCGCATCGTCGCGATGGCCGACAGCCGCA CCTACGGGCTGGACGTCAACGCCGGCCAGACGGTGCAGCCCCAGCCCTTCTCCCTCGTCGGCGACGGCGCCGGCTCGATC TTCAAGATCTTCACCACGGCTGCGGCGCTGGAGATGGGGATGGGTATCAACGCCACACTCGATGTGCCCCAGACGTTTCG GGGCACCGGACTTGGTGACAGCACCGAGCCGGGGTGCCCGCCGAAAACTTGGTGCGTGAGGAACGTCTCCGGGTTCGCCG GCCAGTTGAACGTAACCGATGCACTCGCGAAGTCGCCCAACACCGCGTTCGCCAAGCTGATCTCCCAGATCGGTGTTCCG CGCGCGATGGACATGGCGGTCCGGCTCGGGCTGCGGTCCTACGCCGAGCCGGGAACCGCCCGCGCGTATGACCCCGAGTC CAACGAGAGCATCGCCGATTGGGTCAAGCGGCAGAACCTCGGATCGTTCACACTCGGCCCGCTGGAGCTCAACGCGCTCG AATTGTCCAACGTCGCCGCGACGTTGGCCTCCGGAGGAATGTGGTGCCCGCCCAGCCCGATCGACAAGGTCCTGGACCGC AACGGCGATGAGGTGGCCCTCGCGGCGGCGCCCTGCGAGCAGGTCGTCCCCGAGGGGCTCGCCAACACGATGGCCAATGC GTTGGGCAAGGACCACACCGGAGGAACCGCCACGGGCGCTGCGGGTTCGGTCGGGTGGGATCTTCCGATGTCGGGCAAGA CCGGGACCACCGAGTCGCACCGGTCGTCGGGCTTCCTCGGCTTCACCAATCAGTACGCCGCCGCGAACTACATCTTCAAC GACTCGCCCACCCCGTCAGGTCTGTGCTCGTACCCGCTGCGCCAGTGCAGCGACGGTGACCTCTACGGCGGAACGGAACC GGCCCGGACCTGGTACATGGCGATGAAGCCGATCGCCAATTATTTCGGCCCGGTCGCCATGCCGCCCACCGATCCACGCT ACGTCGACGGCGGACCCGGTAGCGAGGTACCCAGCGTGACCGGGCTGAAGCTCGATGCAGCGCGAAAGAAGCTGTCAGAA GCCGGCTTTCAGGTCGCAGCCGAGCCGACTGCGGTGAACAGCTCCTCGGCGAAGGGCACCGTCGTCGGAACGACTCCGCG GGGTAAGACCATCCCCGGTTCGATCGTCACGATCAACACCAGCACCGGATACGTCCCGGCTCCGGTGTACCAGCCACCCC GCCCGAGCGCGCCATCGGCTCCGAGCGCGCCACCTCCTGTGGAGGCACCACCTCCGCAACCCCCGCCACCCAACGTCTTC GAAATCCCCGGGCTGCCGCCGATAATGCTGCCATGGCCACCGCCACCGCCACCTCCACCGCCGGCACCTCCGCCTCCGCC ACCACCGCCGGCGTGA
Upstream 100 bases:
>100_bases GGGCGCTCAATAGCGAGGCCCACTCAGCGAGAAGCCACGGCGTTTCGCGAGTCCCGCGCAATCCGCTGTCAGGTCCCGCG AACCGTCCTAAGCTGACGGG
Downstream 100 bases:
>100_bases CGCCCGCGCCGCTGAGACGGTGACGATGGCCGTCATTTCCGGAACATGAAACCGGCGTGGCTGCCAAGCTGAACCATGCG CCAGCTGGTCTTCGTCGAGC
Product: glycosyl transferase family protein
Products: NA
Alternate protein names: PBP-1b; PBP1b; Murein polymerase; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Peptidoglycan glycosyltransferase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 831; Mature: 831
Protein sequence:
>831_residues MRDKRRAKWQALARLAGCCLVAGLLAAALMFPFVGGAGSAIMRVSDSATEESTQLIEGEVPIVSTMVDTEGNPIAWLYEQ RRWEVPSNRIANTMKLAIISIEDKRFSEHNGVDWQGTLTGLAGYLQGAERTRGGSTLEQQYVKNFNLLVKAQTDADRRAA VENTPARKLREIRAALAMDAALPKAEILARYLNLVSFGNGAFGVQDAAKTYFGINASELNWQQAAMLAGMVRSPSSLDPY THPDATLERRNVVLNTIIENLPDKADELRAAKDRPLGVLPRPDPLPQGCIAARDRAFFCAYAMEYLARAGLSKEDVARNG YLIRTTLDPKVQDSVKNAIDEVADPTAVGVASVMSVIRPGKDAHRIVAMADSRTYGLDVNAGQTVQPQPFSLVGDGAGSI FKIFTTAAALEMGMGINATLDVPQTFRGTGLGDSTEPGCPPKTWCVRNVSGFAGQLNVTDALAKSPNTAFAKLISQIGVP RAMDMAVRLGLRSYAEPGTARAYDPESNESIADWVKRQNLGSFTLGPLELNALELSNVAATLASGGMWCPPSPIDKVLDR NGDEVALAAAPCEQVVPEGLANTMANALGKDHTGGTATGAAGSVGWDLPMSGKTGTTESHRSSGFLGFTNQYAAANYIFN DSPTPSGLCSYPLRQCSDGDLYGGTEPARTWYMAMKPIANYFGPVAMPPTDPRYVDGGPGSEVPSVTGLKLDAARKKLSE AGFQVAAEPTAVNSSSAKGTVVGTTPRGKTIPGSIVTINTSTGYVPAPVYQPPRPSAPSAPSAPPPVEAPPPQPPPPNVF EIPGLPPIMLPWPPPPPPPPPAPPPPPPPPA
Sequences:
>Translated_831_residues MRDKRRAKWQALARLAGCCLVAGLLAAALMFPFVGGAGSAIMRVSDSATEESTQLIEGEVPIVSTMVDTEGNPIAWLYEQ RRWEVPSNRIANTMKLAIISIEDKRFSEHNGVDWQGTLTGLAGYLQGAERTRGGSTLEQQYVKNFNLLVKAQTDADRRAA VENTPARKLREIRAALAMDAALPKAEILARYLNLVSFGNGAFGVQDAAKTYFGINASELNWQQAAMLAGMVRSPSSLDPY THPDATLERRNVVLNTIIENLPDKADELRAAKDRPLGVLPRPDPLPQGCIAARDRAFFCAYAMEYLARAGLSKEDVARNG YLIRTTLDPKVQDSVKNAIDEVADPTAVGVASVMSVIRPGKDAHRIVAMADSRTYGLDVNAGQTVQPQPFSLVGDGAGSI FKIFTTAAALEMGMGINATLDVPQTFRGTGLGDSTEPGCPPKTWCVRNVSGFAGQLNVTDALAKSPNTAFAKLISQIGVP RAMDMAVRLGLRSYAEPGTARAYDPESNESIADWVKRQNLGSFTLGPLELNALELSNVAATLASGGMWCPPSPIDKVLDR NGDEVALAAAPCEQVVPEGLANTMANALGKDHTGGTATGAAGSVGWDLPMSGKTGTTESHRSSGFLGFTNQYAAANYIFN DSPTPSGLCSYPLRQCSDGDLYGGTEPARTWYMAMKPIANYFGPVAMPPTDPRYVDGGPGSEVPSVTGLKLDAARKKLSE AGFQVAAEPTAVNSSSAKGTVVGTTPRGKTIPGSIVTINTSTGYVPAPVYQPPRPSAPSAPSAPPPVEAPPPQPPPPNVF EIPGLPPIMLPWPPPPPPPPPAPPPPPPPPA >Mature_831_residues MRDKRRAKWQALARLAGCCLVAGLLAAALMFPFVGGAGSAIMRVSDSATEESTQLIEGEVPIVSTMVDTEGNPIAWLYEQ RRWEVPSNRIANTMKLAIISIEDKRFSEHNGVDWQGTLTGLAGYLQGAERTRGGSTLEQQYVKNFNLLVKAQTDADRRAA VENTPARKLREIRAALAMDAALPKAEILARYLNLVSFGNGAFGVQDAAKTYFGINASELNWQQAAMLAGMVRSPSSLDPY THPDATLERRNVVLNTIIENLPDKADELRAAKDRPLGVLPRPDPLPQGCIAARDRAFFCAYAMEYLARAGLSKEDVARNG YLIRTTLDPKVQDSVKNAIDEVADPTAVGVASVMSVIRPGKDAHRIVAMADSRTYGLDVNAGQTVQPQPFSLVGDGAGSI FKIFTTAAALEMGMGINATLDVPQTFRGTGLGDSTEPGCPPKTWCVRNVSGFAGQLNVTDALAKSPNTAFAKLISQIGVP RAMDMAVRLGLRSYAEPGTARAYDPESNESIADWVKRQNLGSFTLGPLELNALELSNVAATLASGGMWCPPSPIDKVLDR NGDEVALAAAPCEQVVPEGLANTMANALGKDHTGGTATGAAGSVGWDLPMSGKTGTTESHRSSGFLGFTNQYAAANYIFN DSPTPSGLCSYPLRQCSDGDLYGGTEPARTWYMAMKPIANYFGPVAMPPTDPRYVDGGPGSEVPSVTGLKLDAARKKLSE AGFQVAAEPTAVNSSSAKGTVVGTTPRGKTIPGSIVTINTSTGYVPAPVYQPPRPSAPSAPSAPPPVEAPPPQPPPPNVF EIPGLPPIMLPWPPPPPPPPPAPPPPPPPPA
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell inner membrane [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=327, Percent_Identity=28.1345565749235, Blast_Score=120, Evalue=2e-28, Organism=Escherichia coli, GI1786343, Length=587, Percent_Identity=25.3833049403748, Blast_Score=118, Evalue=1e-27, Organism=Escherichia coli, GI1789601, Length=180, Percent_Identity=35.5555555555556, Blast_Score=90, Evalue=6e-19, Organism=Escherichia coli, GI1788867, Length=418, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=6e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011813 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 87879; Mature: 87879
Theoretical pI: Translated: 5.90; Mature: 5.90
Prosite motif: PS00356 HTH_LACI_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRDKRRAKWQALARLAGCCLVAGLLAAALMFPFVGGAGSAIMRVSDSATEESTQLIEGEV CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCC PIVSTMVDTEGNPIAWLYEQRRWEVPSNRIANTMKLAIISIEDKRFSEHNGVDWQGTLTG CEEEEEECCCCCCEEEEEECCCCCCCHHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHHH LAGYLQGAERTRGGSTLEQQYVKNFNLLVKAQTDADRRAAVENTPARKLREIRAALAMDA HHHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHH ALPKAEILARYLNLVSFGNGAFGVQDAAKTYFGINASELNWQQAAMLAGMVRSPSSLDPY CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCCCCCCC THPDATLERRNVVLNTIIENLPDKADELRAAKDRPLGVLPRPDPLPQGCIAARDRAFFCA CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHHH YAMEYLARAGLSKEDVARNGYLIRTTLDPKVQDSVKNAIDEVADPTAVGVASVMSVIRPG HHHHHHHHCCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC KDAHRIVAMADSRTYGLDVNAGQTVQPQPFSLVGDGAGSIFKIFTTAAALEMGMGINATL CCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEE DVPQTFRGTGLGDSTEPGCPPKTWCVRNVSGFAGQLNVTDALAKSPNTAFAKLISQIGVP CCCCHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCC RAMDMAVRLGLRSYAEPGTARAYDPESNESIADWVKRQNLGSFTLGPLELNALELSNVAA HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCEEECHHHHHHHHH TLASGGMWCPPSPIDKVLDRNGDEVALAAAPCEQVVPEGLANTMANALGKDHTGGTATGA HHHCCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC AGSVGWDLPMSGKTGTTESHRSSGFLGFTNQYAAANYIFNDSPTPSGLCSYPLRQCSDGD CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCC LYGGTEPARTWYMAMKPIANYFGPVAMPPTDPRYVDGGPGSEVPSVTGLKLDAARKKLSE CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHH AGFQVAAEPTAVNSSSAKGTVVGTTPRGKTIPGSIVTINTSTGYVPAPVYQPPRPSAPSA CCCEEECCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC PSAPPPVEAPPPQPPPPNVFEIPGLPPIMLPWPPPPPPPPPAPPPPPPPPA CCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MRDKRRAKWQALARLAGCCLVAGLLAAALMFPFVGGAGSAIMRVSDSATEESTQLIEGEV CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCC PIVSTMVDTEGNPIAWLYEQRRWEVPSNRIANTMKLAIISIEDKRFSEHNGVDWQGTLTG CEEEEEECCCCCCEEEEEECCCCCCCHHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHHH LAGYLQGAERTRGGSTLEQQYVKNFNLLVKAQTDADRRAAVENTPARKLREIRAALAMDA HHHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHH ALPKAEILARYLNLVSFGNGAFGVQDAAKTYFGINASELNWQQAAMLAGMVRSPSSLDPY CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHCCCCCCCCC THPDATLERRNVVLNTIIENLPDKADELRAAKDRPLGVLPRPDPLPQGCIAARDRAFFCA CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHHH YAMEYLARAGLSKEDVARNGYLIRTTLDPKVQDSVKNAIDEVADPTAVGVASVMSVIRPG HHHHHHHHCCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC KDAHRIVAMADSRTYGLDVNAGQTVQPQPFSLVGDGAGSIFKIFTTAAALEMGMGINATL CCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEE DVPQTFRGTGLGDSTEPGCPPKTWCVRNVSGFAGQLNVTDALAKSPNTAFAKLISQIGVP CCCCHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCC RAMDMAVRLGLRSYAEPGTARAYDPESNESIADWVKRQNLGSFTLGPLELNALELSNVAA HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCEEECHHHHHHHHH TLASGGMWCPPSPIDKVLDRNGDEVALAAAPCEQVVPEGLANTMANALGKDHTGGTATGA HHHCCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC AGSVGWDLPMSGKTGTTESHRSSGFLGFTNQYAAANYIFNDSPTPSGLCSYPLRQCSDGD CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCC LYGGTEPARTWYMAMKPIANYFGPVAMPPTDPRYVDGGPGSEVPSVTGLKLDAARKKLSE CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHH AGFQVAAEPTAVNSSSAKGTVVGTTPRGKTIPGSIVTINTSTGYVPAPVYQPPRPSAPSA CCCEEECCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC PSAPPPVEAPPPQPPPPNVFEIPGLPPIMLPWPPPPPPPPPAPPPPPPPPA CCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]