Click here to switch to the map view.

The map label for this gene is ybdR [H]

Identifier: 119867552

GI number: 119867552

Start: 1617514

End: 1618536

Strand: Reverse

Name: ybdR [H]

Synonym: Mkms_1504

Alternate gene names: 119867552

Gene position: 1618536-1617514 (Counterclockwise)

Preceding gene: 119867553

Following gene: 119867550

Centisome position: 28.21

GC content: 70.48

Gene sequence:

>1023_bases
ATGCGCCAGCTGGTCTTCGTCGAGCCGGGACGGCTCGAGTGGCAGGACGTGCCCGACCCGGAACCCGGACCCGGGCAGGC
CGTCATCCATCCCCTCGCCGTCGCCAGGTGCGACCTCGACTCCGCGATGGCGGGATTCGGCATCTTCCCCGGCCCCTACC
CCGTCGGCCATGAGATCGCCGGAGAAGTTGCCGATGTGGGTGACGGTGTCGAGAGCGTCCGGCCTGGCCAACGCGTCGCC
GTGCCGTTCCAGGTGTCGTGCGGCCACTGCGCGTTCTGCGACCGAGGTCGCTACGCCGCATGTGAACCCCGCTACGCGCG
CGCCGGCGCCGCCTTCGGTTTCGGTCCGGCCGGCGGAGGCCACGGCGGCGGAATCGCTGACCTACTCGTAGTGCCCGACG
CGGACCACATGCTGCTGGCGGCACCGGATGCCATCAGCGACGTCGCGCTGGCCACGATTCCCGACAACGTCGTCGATGCG
TACCGCACGGTCGTCGACGGCCTGCGCGAGCGTCCCGGCGCCGACGTCCTGATCGTTGGAGGCGACGCCCCCTCGATCAG
CCTGTACGCGGTCCTCTGCGCGCGGGCACTGGGAGCGGGCGCCGTGCGCTACGCCGACAACGATCCGCTGCGCCTCCACG
TGGCCTCCGATCTGGGCGCCGAGACGATCGATGTGGGCGCACAGTTCCCGCGCCGGCTGCCGCGGTCGCCGATCGTCGTC
GGCGCCTCGTTGAGTGTGGAGGGCTTGCACTGCGCCATCCGTTCGACAGAGGCGTACGGACGCCTGACGGTGGTGACGAT
CCACTTCGCCGCCCAGACGCCGCTGCCGTTGTTGGAGATGTACACCCGCGGGATCACGGTGCATACGTCGCGGGCCGACT
CCCGGCGCTACCTACCCGACGTGCTCGCGATGGTGGCCGCGGGCCGGATCGATCCCCTCGCGGTGCCCACGACGGTGATC
GGCTGGGACGACGCGGCCGAGCACTGGCTGGATCCAGGTCTGAAGATCGTCGTGACCAGATGA

Upstream 100 bases:

>100_bases
GCCTCCGCCACCACCGCCGGCGTGACGCCCGCGCCGCTGAGACGGTGACGATGGCCGTCATTTCCGGAACATGAAACCGG
CGTGGCTGCCAAGCTGAACC

Downstream 100 bases:

>100_bases
GGGGCTTCTCAGCCGTCCGGCCGGTGATCGGCAAAGTTAGCCTCCGCGGACAGCTCGCCTCCACGCAAGCGGGTTCAGGT
TCCGGAACGGGTCGATTTCG

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRQLVFVEPGRLEWQDVPDPEPGPGQAVIHPLAVARCDLDSAMAGFGIFPGPYPVGHEIAGEVADVGDGVESVRPGQRVA
VPFQVSCGHCAFCDRGRYAACEPRYARAGAAFGFGPAGGGHGGGIADLLVVPDADHMLLAAPDAISDVALATIPDNVVDA
YRTVVDGLRERPGADVLIVGGDAPSISLYAVLCARALGAGAVRYADNDPLRLHVASDLGAETIDVGAQFPRRLPRSPIVV
GASLSVEGLHCAIRSTEAYGRLTVVTIHFAAQTPLPLLEMYTRGITVHTSRADSRRYLPDVLAMVAAGRIDPLAVPTTVI
GWDDAAEHWLDPGLKIVVTR

Sequences:

>Translated_340_residues
MRQLVFVEPGRLEWQDVPDPEPGPGQAVIHPLAVARCDLDSAMAGFGIFPGPYPVGHEIAGEVADVGDGVESVRPGQRVA
VPFQVSCGHCAFCDRGRYAACEPRYARAGAAFGFGPAGGGHGGGIADLLVVPDADHMLLAAPDAISDVALATIPDNVVDA
YRTVVDGLRERPGADVLIVGGDAPSISLYAVLCARALGAGAVRYADNDPLRLHVASDLGAETIDVGAQFPRRLPRSPIVV
GASLSVEGLHCAIRSTEAYGRLTVVTIHFAAQTPLPLLEMYTRGITVHTSRADSRRYLPDVLAMVAAGRIDPLAVPTTVI
GWDDAAEHWLDPGLKIVVTR
>Mature_340_residues
MRQLVFVEPGRLEWQDVPDPEPGPGQAVIHPLAVARCDLDSAMAGFGIFPGPYPVGHEIAGEVADVGDGVESVRPGQRVA
VPFQVSCGHCAFCDRGRYAACEPRYARAGAAFGFGPAGGGHGGGIADLLVVPDADHMLLAAPDAISDVALATIPDNVVDA
YRTVVDGLRERPGADVLIVGGDAPSISLYAVLCARALGAGAVRYADNDPLRLHVASDLGAETIDVGAQFPRRLPRSPIVV
GASLSVEGLHCAIRSTEAYGRLTVVTIHFAAQTPLPLLEMYTRGITVHTSRADSRRYLPDVLAMVAAGRIDPLAVPTTVI
GWDDAAEHWLDPGLKIVVTR

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786825, Length=239, Percent_Identity=31.3807531380753, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788075, Length=225, Percent_Identity=29.7777777777778, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790045, Length=209, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI226510992, Length=322, Percent_Identity=27.0186335403727, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788073, Length=339, Percent_Identity=23.8938053097345, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787863, Length=338, Percent_Identity=24.8520710059172, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082125, Length=219, Percent_Identity=29.6803652968037, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=325, Percent_Identity=27.6923076923077, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=321, Percent_Identity=26.1682242990654, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35696; Mature: 35696

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQLVFVEPGRLEWQDVPDPEPGPGQAVIHPLAVARCDLDSAMAGFGIFPGPYPVGHEIA
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHH
GEVADVGDGVESVRPGQRVAVPFQVSCGHCAFCDRGRYAACEPRYARAGAAFGFGPAGGG
HHHHHHCCCHHHCCCCCEEEEEEEECCCCEEEECCCCCCCCCCCHHHCCCCCCCCCCCCC
HGGGIADLLVVPDADHMLLAAPDAISDVALATIPDNVVDAYRTVVDGLRERPGADVLIVG
CCCCEEEEEEECCCCCEEEECCCCHHCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEC
GDAPSISLYAVLCARALGAGAVRYADNDPLRLHVASDLGAETIDVGAQFPRRLPRSPIVV
CCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCEEHHCCHHHHHCCCCCEEE
GASLSVEGLHCAIRSTEAYGRLTVVTIHFAAQTPLPLLEMYTRGITVHTSRADSRRYLPD
ECCCCCCCEEEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHCCEEEEECCCCCHHHHHH
VLAMVAAGRIDPLAVPTTVIGWDDAAEHWLDPGLKIVVTR
HHHHHHCCCCCCCCCCEEEECCCHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MRQLVFVEPGRLEWQDVPDPEPGPGQAVIHPLAVARCDLDSAMAGFGIFPGPYPVGHEIA
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHH
GEVADVGDGVESVRPGQRVAVPFQVSCGHCAFCDRGRYAACEPRYARAGAAFGFGPAGGG
HHHHHHCCCHHHCCCCCEEEEEEEECCCCEEEECCCCCCCCCCCHHHCCCCCCCCCCCCC
HGGGIADLLVVPDADHMLLAAPDAISDVALATIPDNVVDAYRTVVDGLRERPGADVLIVG
CCCCEEEEEEECCCCCEEEECCCCHHCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEC
GDAPSISLYAVLCARALGAGAVRYADNDPLRLHVASDLGAETIDVGAQFPRRLPRSPIVV
CCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCEEHHCCHHHHHCCCCCEEE
GASLSVEGLHCAIRSTEAYGRLTVVTIHFAAQTPLPLLEMYTRGITVHTSRADSRRYLPD
ECCCCCCCEEEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHCCEEEEECCCCCHHHHHH
VLAMVAAGRIDPLAVPTTVIGWDDAAEHWLDPGLKIVVTR
HHHHHHCCCCCCCCCCEEEECCCHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]