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The map label for this gene is walR [H]

Identifier: 119867514

GI number: 119867514

Start: 1577975

End: 1578760

Strand: Direct

Name: walR [H]

Synonym: Mkms_1464

Alternate gene names: 119867514

Gene position: 1577975-1578760 (Clockwise)

Preceding gene: 119867513

Following gene: 119867518

Centisome position: 27.5

GC content: 66.28

Gene sequence:

>786_bases
ATGCCGAGCGTCGAAGCCAGCACAGGTGAGGAGTCCGCCACGTCTATCGAGCCACACCACCGATGGAGTCGGTCAGCGCC
AGCGCCAGCGCCGGCGGCTGCCGGTCGTATCCGTGTGCTGGTGGTGGAACCGCGACGCATCTACGCCACAATGCTGGCCC
GGCATCTGCACGCCGGCGATTTCACCGTCGAGGTGAGGCACTCCTACGACGGTGCCGTCTCGGATCTGCGTGACCTCGAC
CCCGACGTGGTGGTCGTGTGTGCCGGTCCACATGAGGTCGGGTTGGCTCTTGTCGACCGGATCCGACACGTCTCCCGCGC
CGCAGTGGTCGCACTTGACGACACGGTGCTTTCGTCGCTGCTCGCCAACGCCGATCCGGGGCACTCGCCAGAAGCTGACA
TGCTCGGAAGGCGAATACGCCACGCGCTGAGACGGTATGGCGCCGCTGATGCTATCGACGCTGGCGGTGGTGGGAGCCGG
GCAGTCCAGCGGCGGGAGATCGCCGACCTGGTGATCGACCTGGCTGCCCACCGGGTGTATCAGCGAGGGACCGTCATCGC
CTTGACGCGGCTGGAGTTTGCCATCCTGGCCGCGCTGTCGGAAAGCCCGGGTGAACCTCTCACGTGTCGGCATCTGCAGG
CCATCTTGTGGGGGACGTCGCACGCCGGTGGCCGGTCGGCTCTGGGTGTGCACGTCAGCAACCTGCGGCGCAAATTAGGT
GATGACCCCGTGCTGCCCCGGTACGTCAGGACTGTTCGTGGCCTCGGTTACTGTTTGGTGGGCTGA

Upstream 100 bases:

>100_bases
CACATTCGCGACGACGCGCCCAATCGCGCAACCCGCCATCTACGTAGTAACTACGTAGATGGCGGGTACGGTGATACCGG
GCTGCCCAGCGGGGAGAGGG

Downstream 100 bases:

>100_bases
GGACAGCGGCGCCATCGCGACGGTGGTGCGATGCGTGCGCCGAGGCCACAAAGTGGCTCTTCGCCACTGCGCGTTCAGGT
TTCGATGATGCGGACAACAT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MPSVEASTGEESATSIEPHHRWSRSAPAPAPAAAGRIRVLVVEPRRIYATMLARHLHAGDFTVEVRHSYDGAVSDLRDLD
PDVVVVCAGPHEVGLALVDRIRHVSRAAVVALDDTVLSSLLANADPGHSPEADMLGRRIRHALRRYGAADAIDAGGGGSR
AVQRREIADLVIDLAAHRVYQRGTVIALTRLEFAILAALSESPGEPLTCRHLQAILWGTSHAGGRSALGVHVSNLRRKLG
DDPVLPRYVRTVRGLGYCLVG

Sequences:

>Translated_261_residues
MPSVEASTGEESATSIEPHHRWSRSAPAPAPAAAGRIRVLVVEPRRIYATMLARHLHAGDFTVEVRHSYDGAVSDLRDLD
PDVVVVCAGPHEVGLALVDRIRHVSRAAVVALDDTVLSSLLANADPGHSPEADMLGRRIRHALRRYGAADAIDAGGGGSR
AVQRREIADLVIDLAAHRVYQRGTVIALTRLEFAILAALSESPGEPLTCRHLQAILWGTSHAGGRSALGVHVSNLRRKLG
DDPVLPRYVRTVRGLGYCLVG
>Mature_260_residues
PSVEASTGEESATSIEPHHRWSRSAPAPAPAAAGRIRVLVVEPRRIYATMLARHLHAGDFTVEVRHSYDGAVSDLRDLDP
DVVVVCAGPHEVGLALVDRIRHVSRAAVVALDDTVLSSLLANADPGHSPEADMLGRRIRHALRRYGAADAIDAGGGGSRA
VQRREIADLVIDLAAHRVYQRGTVIALTRLEFAILAALSESPGEPLTCRHLQAILWGTSHAGGRSALGVHVSNLRRKLGD
DPVLPRYVRTVRGLGYCLVG

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=185, Percent_Identity=30.2702702702703, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789809, Length=123, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=122, Percent_Identity=34.4262295081967, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=27.3913043478261, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27981; Mature: 27850

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVEASTGEESATSIEPHHRWSRSAPAPAPAAAGRIRVLVVEPRRIYATMLARHLHAGD
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCC
FTVEVRHSYDGAVSDLRDLDPDVVVVCAGPHEVGLALVDRIRHVSRAAVVALDDTVLSSL
EEEEEECCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHH
LANADPGHSPEADMLGRRIRHALRRYGAADAIDAGGGGSRAVQRREIADLVIDLAAHRVY
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QRGTVIALTRLEFAILAALSESPGEPLTCRHLQAILWGTSHAGGRSALGVHVSNLRRKLG
HCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
DDPVLPRYVRTVRGLGYCLVG
CCCCCHHHHHHHHHCCEEECC
>Mature Secondary Structure 
PSVEASTGEESATSIEPHHRWSRSAPAPAPAAAGRIRVLVVEPRRIYATMLARHLHAGD
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCC
FTVEVRHSYDGAVSDLRDLDPDVVVVCAGPHEVGLALVDRIRHVSRAAVVALDDTVLSSL
EEEEEECCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHH
LANADPGHSPEADMLGRRIRHALRRYGAADAIDAGGGGSRAVQRREIADLVIDLAAHRVY
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QRGTVIALTRLEFAILAALSESPGEPLTCRHLQAILWGTSHAGGRSALGVHVSNLRRKLG
HCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
DDPVLPRYVRTVRGLGYCLVG
CCCCCHHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA