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The map label for this gene is nudC [H]

Identifier: 119867475

GI number: 119867475

Start: 1528017

End: 1528952

Strand: Direct

Name: nudC [H]

Synonym: Mkms_1425

Alternate gene names: 119867475

Gene position: 1528017-1528952 (Clockwise)

Preceding gene: 119867474

Following gene: 119867477

Centisome position: 26.63

GC content: 72.22

Gene sequence:

>936_bases
GTGAGCGCCTTCCAGTCCCTGCGTAACACCCCGCTGCTCTCCCGCGTCGGCGCCGACCGCGCCGACGCGTTGCGCACCGA
CATCGACGCCGCCACCGCCGGCTGGGCCGACGCATTGCTGTTGCGGGTGGACCGGCGCAATCAGGTGCTGATCGCGGGCG
GACAGGCGGTGCTGGGACGGGCGAGCGCACTGGCCGACGCACCTCCCGAACACGCCGTCTTCCTCGGACGGCTGCGCGAC
GGCCGCCACGTCTGGGGCGTGCGGGCCGCGTTGGAGGCGCCCGAGGACGGCACCGACGCCGAGGTGCTCGACCTGCGGCG
GGCCGGCCAGATCTTCGACGACACCAGCGCCCAGCTCGTGGCCACCGCCACCGCGCTGCTCAACTGGCACGACCACGCCC
GGTTCAGCCCGGTCGACGGCGCACCCACCAAACCGGTCAAGGCCGGCTGGTCGAGGGTGAACCCGGTCAACGGGCACGAG
GAGTTCCCGCGCATCGACCCCGCGGTGATCTGCCTGGTGCACGACGGACACGACCGCGCGGTGCTGGCCCGCCAGACGCT
TTGGCCGGAGCGGTTGTTCTCGATCCTCGCCGGCTTCGTCGAGGCCGGTGAGTCGTTCGAATCGTGCGTGGTGCGCGAGA
TCGCCGAGGAGGTCGGGCTGACGGTGACCGACGTGCGCTACCTGGGCAGCCAGCCGTGGCCGTTCCCGCGCTCGCTGATG
GTCGGATTCCACGCCGTCGCTGATCCCGAGCAGCCGTTCGCGTTCAACGACGGCGAGATCGCCGAGGCCGGGTGGTTCAC
CCGCGCCGAGGTGCGCGCCGCGCTGGCCGAGGGGGACTGGAACGCCGCGGCCGGCGGATCACCGTCGCGGCTGCTGCTGC
CCGGTTCGATCTCGATCGCCCGGGAGATCATCGAATCCTGGGCCGCACTGGACTGA

Upstream 100 bases:

>100_bases
TCGTGCGCGACGGGGCACTGGTACGCGTCGACGCCCCCGAGGTCGACGCGCTGGAACTGGGTGACCGGCTGCTCTACATC
CGCAGCGCGGACGCCGAACG

Downstream 100 bases:

>100_bases
TCCGCTGGGGTCAGCGACCCAGTTTGGCCTTGACGTCCTTGATGCTCGGGTTGGTCAGCGCCGAACCGTCCGGGAACTTC
ACCGTCGGCACGGTCTGGTT

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSAFQSLRNTPLLSRVGADRADALRTDIDAATAGWADALLLRVDRRNQVLIAGGQAVLGRASALADAPPEHAVFLGRLRD
GRHVWGVRAALEAPEDGTDAEVLDLRRAGQIFDDTSAQLVATATALLNWHDHARFSPVDGAPTKPVKAGWSRVNPVNGHE
EFPRIDPAVICLVHDGHDRAVLARQTLWPERLFSILAGFVEAGESFESCVVREIAEEVGLTVTDVRYLGSQPWPFPRSLM
VGFHAVADPEQPFAFNDGEIAEAGWFTRAEVRAALAEGDWNAAAGGSPSRLLLPGSISIAREIIESWAALD

Sequences:

>Translated_311_residues
MSAFQSLRNTPLLSRVGADRADALRTDIDAATAGWADALLLRVDRRNQVLIAGGQAVLGRASALADAPPEHAVFLGRLRD
GRHVWGVRAALEAPEDGTDAEVLDLRRAGQIFDDTSAQLVATATALLNWHDHARFSPVDGAPTKPVKAGWSRVNPVNGHE
EFPRIDPAVICLVHDGHDRAVLARQTLWPERLFSILAGFVEAGESFESCVVREIAEEVGLTVTDVRYLGSQPWPFPRSLM
VGFHAVADPEQPFAFNDGEIAEAGWFTRAEVRAALAEGDWNAAAGGSPSRLLLPGSISIAREIIESWAALD
>Mature_310_residues
SAFQSLRNTPLLSRVGADRADALRTDIDAATAGWADALLLRVDRRNQVLIAGGQAVLGRASALADAPPEHAVFLGRLRDG
RHVWGVRAALEAPEDGTDAEVLDLRRAGQIFDDTSAQLVATATALLNWHDHARFSPVDGAPTKPVKAGWSRVNPVNGHEE
FPRIDPAVICLVHDGHDRAVLARQTLWPERLFSILAGFVEAGESFESCVVREIAEEVGLTVTDVRYLGSQPWPFPRSLMV
GFHAVADPEQPFAFNDGEIAEAGWFTRAEVRAALAEGDWNAAAGGSPSRLLLPGSISIAREIIESWAALD

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI50593112, Length=228, Percent_Identity=39.4736842105263, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI13899267, Length=209, Percent_Identity=34.9282296650718, Blast_Score=128, Evalue=7e-30,
Organism=Escherichia coli, GI48994995, Length=224, Percent_Identity=29.4642857142857, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI212645999, Length=200, Percent_Identity=33, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71986510, Length=201, Percent_Identity=32.8358208955224, Blast_Score=88, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321371, Length=226, Percent_Identity=31.858407079646, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 33558; Mature: 33427

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFQSLRNTPLLSRVGADRADALRTDIDAATAGWADALLLRVDRRNQVLIAGGQAVLGR
CCHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHEEECCCCEEEEECCHHHHHH
ASALADAPPEHAVFLGRLRDGRHVWGVRAALEAPEDGTDAEVLDLRRAGQIFDDTSAQLV
HHHHCCCCCCHHEEEEECCCCCEEEHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
ATATALLNWHDHARFSPVDGAPTKPVKAGWSRVNPVNGHEEFPRIDPAVICLVHDGHDRA
HHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCE
VLARQTLWPERLFSILAGFVEAGESFESCVVREIAEEVGLTVTDVRYLGSQPWPFPRSLM
EHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEHHHHCCCCCCCCHHHH
VGFHAVADPEQPFAFNDGEIAEAGWFTRAEVRAALAEGDWNAAAGGSPSRLLLPGSISIA
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHH
REIIESWAALD
HHHHHHHHCCC
>Mature Secondary Structure 
SAFQSLRNTPLLSRVGADRADALRTDIDAATAGWADALLLRVDRRNQVLIAGGQAVLGR
CHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHEEECCCCEEEEECCHHHHHH
ASALADAPPEHAVFLGRLRDGRHVWGVRAALEAPEDGTDAEVLDLRRAGQIFDDTSAQLV
HHHHCCCCCCHHEEEEECCCCCEEEHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
ATATALLNWHDHARFSPVDGAPTKPVKAGWSRVNPVNGHEEFPRIDPAVICLVHDGHDRA
HHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCE
VLARQTLWPERLFSILAGFVEAGESFESCVVREIAEEVGLTVTDVRYLGSQPWPFPRSLM
EHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEHHHHCCCCCCCCHHHH
VGFHAVADPEQPFAFNDGEIAEAGWFTRAEVRAALAEGDWNAAAGGSPSRLLLPGSISIA
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHH
REIIESWAALD
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]