| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is uhpA [C]
Identifier: 119867438
GI number: 119867438
Start: 1488628
End: 1491273
Strand: Reverse
Name: uhpA [C]
Synonym: Mkms_1388
Alternate gene names: 119867438
Gene position: 1491273-1488628 (Counterclockwise)
Preceding gene: 119867439
Following gene: 119867434
Centisome position: 25.99
GC content: 71.73
Gene sequence:
>2646_bases GTGCGCGCCTACGATGTGACCGTGATCATCGTGTCCGGGGCATGCGTCGGGCGCGACCGCGAACTCACCGAACTCGCCGC GCGCTGCGCGGCGACCGTGACCTCGGGCGCGGACGTCGTCGCCGTGCTCGGACCGCCGGGGATCGGTAAGTCGACGCTGC TCAACCGACTGGCCACCGACCACGGCCACGCCCACACCGCGCGTGCACTGCCGTGGGAGGCCGATGTCCCGGGGGCGGTG CTCGGCCAGTTGCTCCAGGAGGACATGACCGCCGACCCGGCGGCCCGCCTTCTCGATCGGGTCACGGCACACCGTCCGGC GCTGGTGATCGTCGACGATGCCGAGTATTGCGACGCGCTGTCGCTGCAGGTGTTGGAAACCGCGGTGCGCCACCACCGCA GCCTTGCGCTGCTCGTGGTGCTCGCGATGAGGAACCCGGACTTCGCGGCAATGCGCTTCGTCTCGGCGGAGGTGCGGTTG ACCGGCCTGGACACCGCGGGCATGGCGGAACTGGCGTCGTTGCGCGGGCGGGTCCTGCACCCGACCATGGTGGACCTGCT CACCCGGCACACCGAAGGGAATCCCCGCGACGCGCTGGCGCTGCTCACCGAAGTGCCCGCGGCGGTGTGGTCGCGCCATG ACGCGCAGTTGCCCGCACCGGCGCACACCGTGTCTGCGGTGCGCTCGCGCCTCGAGGGCTGCGACGCACACGGCCGGGCG CTGGTGGAGGCACTCGCGGTGTTGGGCGACGGCGGATCCCTCGGCGAGGCGGCGCAACTCGCCGGTGTCGACGAACCGCT GAGCGCGGTCGACCAGGCGGTGGGTGCCGAGTTGATCACCACGACAACGGGTTTCGGCGTCGCGCTCCGGTCGAGCCTGG TCCGGTCGGCGGTCCTCGAGGTGATGGGCGCACACGCCGCCGGTGACGCGCACCGGCGGGCGGCCGACGTCGTCGATGAT CCGGTCCGCCGGCTGCGGCATCTGGTGGCGGCCACGCCCGTCCCGGACGCCGCACTGGCCGACCAGGTCGACGCGATGGC GCGCGAACGCGGCGCCGAAGGCGCCTGGGCGGAGGCGGCGAGCCTGTTCCGCGAGGCCGGCAGGCTGACCCCGGATGCAC TGCTGCGCGACGACCGGCTGACCCGCTCGGTGGACGCGCTCGTAGCGGCCGGTGACACCGCGGGCGCCGCCGCGTTGACA CCCGCGGTCGAGAGTCTGCGGGAGACACCGCTGCGCGATGCAGCGCTGGCATACCTGGCGATCGTGCGCGGACGGGCGGC CGAGGCGGACGTCCGGTTGCGCCGCGCGTGGGGCATCGTCAACGCCGACCGCGATCCCGAGGCGGCAGCGTTGATCGCCG GCCGGTACGTCCTGCACGCGCTGATGCGTTGTCGCGGAGCCGAGATCGTGCAGTGGGCCGACCGCGCCATCGAGCTGTCG GGGGACGACTCCCCCGCCGGCGTCGAGGCCGCCGCGATCCGCGGGCTCGGGTTGTCCGCGGTCGGTCATTCCGCCCGCGC CGCGGCCGCCTACGACGAGTTGAGTGACCGTATCCGCTACGGCGCCCAGGCGCAGCGCATCGCGATGGGGCGCGGCTGGC TGCAATTGGCAGGCGACGACCTCGATGGCGCCCGCAGCAGCCTCGAGGGGGCGGTGTCCACCACCGAACTGGGTGGATCG GCACGCATCGCGCTGTGGGCGTTGGGCTGGCTGGCCCGCGTGCAGTTCCTCACCGGCGACTGGGATCAGGCGTTGAGCAC CGTCGAGCGTGGACGCCTGACCGCGGCCTCCAGCGGCATCGTTCTGGTCACTCCGCTTCTCGAGTGGACCGCCACCCAGA TCCACGCCCTGCGCGGTGACTTCGAGGCCGCGCAGGCAGCGGTGCGGACCGCGGACACAGTCACCCAGGGCTACGAGATG ATGCATCTGGCAACGTTTCTCGCCCGGGCGCAGGTCGCCGAGGCCGAGGCGGATTACGCCGGGGTGCGTCGGGCACTGGA ACCGCTGAGGCGTATGTCGCAGCACATCACCACCGAACCCGCATTGTGGCCGTGGGCCGATGTGCTGGCCAACGCCATGG TTCTCGACGGGCAGCCCGACGCCGCAGACGCTTTCCTCGGCCCCCACGAACAGCGGGCCGACCGGCGTGCCCAGCGGTCG ACCCGGGCCCGGTTGGGCTATGCCCGCGGACGGATACTGGGCGCCGCGGGTGACATCAACGCCGCGCGGCGGGCCTTCGA CGAGTCGCTGGCGTTGCTCGACGGCCTTCCGCTGCGTTACGACCTGGCCCGCGTCAACTTCGCCTACGGGCAGACGCTGC GCCGGGCCGGTAAACGCCGCGACGCCGACGCGGTCATCAGCACGGCGCGTGATCTGTACCTGTCACTCGGGGCTCAGACC TACGTGGCCCGTTGCGAACGCGAGCTGAAGGCCGGCGGTGTGCACGTCGTGCGTGGACCACGCGGCCACGCGGAGCTCAC CCCGCAGGAGGATGCAGTCACAACCCTTGTTGCACAGGGTCTTTCGAATCGTGAGGTGGCTGCCGAACTGTACGTCTCGC CGAAGACCGTGCAGTATCACCTGACCCGGATCTACGCCAAGCTCGGAGTGCGCTCACGTACGGAACTCGCCGCGCTGCGC AGTTGA
Upstream 100 bases:
>100_bases ACAGGCGGCGGCCATCTGCTTCCTGGCCTCCGACGAGGCGTCCTACATCACCGGTTCGGTCCTGCCGGTCGCCGGCGGTG ATCAGGGCTAGCGGCGGGCG
Downstream 100 bases:
>100_bases ACCCGCCCGTCGGTGACCGGCGCGGCGGTCGCGGCGACCACGTCGTCGAAGGTGACCCCCGGCGCCGTCTCGACGAGCTC GAATCCGGCACCGGTCACGT
Product: LuxR family transcriptional regulator
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 881; Mature: 881
Protein sequence:
>881_residues MRAYDVTVIIVSGACVGRDRELTELAARCAATVTSGADVVAVLGPPGIGKSTLLNRLATDHGHAHTARALPWEADVPGAV LGQLLQEDMTADPAARLLDRVTAHRPALVIVDDAEYCDALSLQVLETAVRHHRSLALLVVLAMRNPDFAAMRFVSAEVRL TGLDTAGMAELASLRGRVLHPTMVDLLTRHTEGNPRDALALLTEVPAAVWSRHDAQLPAPAHTVSAVRSRLEGCDAHGRA LVEALAVLGDGGSLGEAAQLAGVDEPLSAVDQAVGAELITTTTGFGVALRSSLVRSAVLEVMGAHAAGDAHRRAADVVDD PVRRLRHLVAATPVPDAALADQVDAMARERGAEGAWAEAASLFREAGRLTPDALLRDDRLTRSVDALVAAGDTAGAAALT PAVESLRETPLRDAALAYLAIVRGRAAEADVRLRRAWGIVNADRDPEAAALIAGRYVLHALMRCRGAEIVQWADRAIELS GDDSPAGVEAAAIRGLGLSAVGHSARAAAAYDELSDRIRYGAQAQRIAMGRGWLQLAGDDLDGARSSLEGAVSTTELGGS ARIALWALGWLARVQFLTGDWDQALSTVERGRLTAASSGIVLVTPLLEWTATQIHALRGDFEAAQAAVRTADTVTQGYEM MHLATFLARAQVAEAEADYAGVRRALEPLRRMSQHITTEPALWPWADVLANAMVLDGQPDAADAFLGPHEQRADRRAQRS TRARLGYARGRILGAAGDINAARRAFDESLALLDGLPLRYDLARVNFAYGQTLRRAGKRRDADAVISTARDLYLSLGAQT YVARCERELKAGGVHVVRGPRGHAELTPQEDAVTTLVAQGLSNREVAAELYVSPKTVQYHLTRIYAKLGVRSRTELAALR S
Sequences:
>Translated_881_residues MRAYDVTVIIVSGACVGRDRELTELAARCAATVTSGADVVAVLGPPGIGKSTLLNRLATDHGHAHTARALPWEADVPGAV LGQLLQEDMTADPAARLLDRVTAHRPALVIVDDAEYCDALSLQVLETAVRHHRSLALLVVLAMRNPDFAAMRFVSAEVRL TGLDTAGMAELASLRGRVLHPTMVDLLTRHTEGNPRDALALLTEVPAAVWSRHDAQLPAPAHTVSAVRSRLEGCDAHGRA LVEALAVLGDGGSLGEAAQLAGVDEPLSAVDQAVGAELITTTTGFGVALRSSLVRSAVLEVMGAHAAGDAHRRAADVVDD PVRRLRHLVAATPVPDAALADQVDAMARERGAEGAWAEAASLFREAGRLTPDALLRDDRLTRSVDALVAAGDTAGAAALT PAVESLRETPLRDAALAYLAIVRGRAAEADVRLRRAWGIVNADRDPEAAALIAGRYVLHALMRCRGAEIVQWADRAIELS GDDSPAGVEAAAIRGLGLSAVGHSARAAAAYDELSDRIRYGAQAQRIAMGRGWLQLAGDDLDGARSSLEGAVSTTELGGS ARIALWALGWLARVQFLTGDWDQALSTVERGRLTAASSGIVLVTPLLEWTATQIHALRGDFEAAQAAVRTADTVTQGYEM MHLATFLARAQVAEAEADYAGVRRALEPLRRMSQHITTEPALWPWADVLANAMVLDGQPDAADAFLGPHEQRADRRAQRS TRARLGYARGRILGAAGDINAARRAFDESLALLDGLPLRYDLARVNFAYGQTLRRAGKRRDADAVISTARDLYLSLGAQT YVARCERELKAGGVHVVRGPRGHAELTPQEDAVTTLVAQGLSNREVAAELYVSPKTVQYHLTRIYAKLGVRSRTELAALR S >Mature_881_residues MRAYDVTVIIVSGACVGRDRELTELAARCAATVTSGADVVAVLGPPGIGKSTLLNRLATDHGHAHTARALPWEADVPGAV LGQLLQEDMTADPAARLLDRVTAHRPALVIVDDAEYCDALSLQVLETAVRHHRSLALLVVLAMRNPDFAAMRFVSAEVRL TGLDTAGMAELASLRGRVLHPTMVDLLTRHTEGNPRDALALLTEVPAAVWSRHDAQLPAPAHTVSAVRSRLEGCDAHGRA LVEALAVLGDGGSLGEAAQLAGVDEPLSAVDQAVGAELITTTTGFGVALRSSLVRSAVLEVMGAHAAGDAHRRAADVVDD PVRRLRHLVAATPVPDAALADQVDAMARERGAEGAWAEAASLFREAGRLTPDALLRDDRLTRSVDALVAAGDTAGAAALT PAVESLRETPLRDAALAYLAIVRGRAAEADVRLRRAWGIVNADRDPEAAALIAGRYVLHALMRCRGAEIVQWADRAIELS GDDSPAGVEAAAIRGLGLSAVGHSARAAAAYDELSDRIRYGAQAQRIAMGRGWLQLAGDDLDGARSSLEGAVSTTELGGS ARIALWALGWLARVQFLTGDWDQALSTVERGRLTAASSGIVLVTPLLEWTATQIHALRGDFEAAQAAVRTADTVTQGYEM MHLATFLARAQVAEAEADYAGVRRALEPLRRMSQHITTEPALWPWADVLANAMVLDGQPDAADAFLGPHEQRADRRAQRS TRARLGYARGRILGAAGDINAARRAFDESLALLDGLPLRYDLARVNFAYGQTLRRAGKRRDADAVISTARDLYLSLGAQT YVARCERELKAGGVHVVRGPRGHAELTPQEDAVTTLVAQGLSNREVAAELYVSPKTVQYHLTRIYAKLGVRSRTELAALR S
Specific function: Appears To Be The Positive Activator Of Uhpt Transcription. [C]
COG id: COG2771
COG function: function code K; DNA-binding HTH domain-containing proteins
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000767 - InterPro: IPR016032 - InterPro: IPR011990 - InterPro: IPR000792 - InterPro: IPR011991 [H]
Pfam domain/function: PF00196 GerE [H]
EC number: NA
Molecular weight: Translated: 93665; Mature: 93665
Theoretical pI: Translated: 6.48; Mature: 6.48
Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRAYDVTVIIVSGACVGRDRELTELAARCAATVTSGADVVAVLGPPGIGKSTLLNRLATD CCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHC HGHAHTARALPWEADVPGAVLGQLLQEDMTADPAARLLDRVTAHRPALVIVDDAEYCDAL CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHH SLQVLETAVRHHRSLALLVVLAMRNPDFAAMRFVSAEVRLTGLDTAGMAELASLRGRVLH HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHCCCCCC PTMVDLLTRHTEGNPRDALALLTEVPAAVWSRHDAQLPAPAHTVSAVRSRLEGCDAHGRA HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH LVEALAVLGDGGSLGEAAQLAGVDEPLSAVDQAVGAELITTTTGFGVALRSSLVRSAVLE HHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHH VMGAHAAGDAHRRAADVVDDPVRRLRHLVAATPVPDAALADQVDAMARERGAEGAWAEAA HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH SLFREAGRLTPDALLRDDRLTRSVDALVAAGDTAGAAALTPAVESLRETPLRDAALAYLA HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH IVRGRAAEADVRLRRAWGIVNADRDPEAAALIAGRYVLHALMRCRGAEIVQWADRAIELS HHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEC GDDSPAGVEAAAIRGLGLSAVGHSARAAAAYDELSDRIRYGAQAQRIAMGRGWLQLAGDD CCCCCCCCHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCC LDGARSSLEGAVSTTELGGSARIALWALGWLARVQFLTGDWDQALSTVERGRLTAASSGI CHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECCCCE VLVTPLLEWTATQIHALRGDFEAAQAAVRTADTVTQGYEMMHLATFLARAQVAEAEADYA EEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GVRRALEPLRRMSQHITTEPALWPWADVLANAMVLDGQPDAADAFLGPHEQRADRRAQRS HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCEEECCCCCCCHHHCCCCHHHHHHHHHHH TRARLGYARGRILGAAGDINAARRAFDESLALLDGLPLRYDLARVNFAYGQTLRRAGKRR HHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCC DADAVISTARDLYLSLGAQTYVARCERELKAGGVHVVRGPRGHAELTPQEDAVTTLVAQG CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHC LSNREVAAELYVSPKTVQYHLTRIYAKLGVRSRTELAALRS CCCCCHHHHEEECCCHHHHHHHHHHHHHCCCCHHHHHHHCC >Mature Secondary Structure MRAYDVTVIIVSGACVGRDRELTELAARCAATVTSGADVVAVLGPPGIGKSTLLNRLATD CCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHC HGHAHTARALPWEADVPGAVLGQLLQEDMTADPAARLLDRVTAHRPALVIVDDAEYCDAL CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHH SLQVLETAVRHHRSLALLVVLAMRNPDFAAMRFVSAEVRLTGLDTAGMAELASLRGRVLH HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHCCCCCC PTMVDLLTRHTEGNPRDALALLTEVPAAVWSRHDAQLPAPAHTVSAVRSRLEGCDAHGRA HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH LVEALAVLGDGGSLGEAAQLAGVDEPLSAVDQAVGAELITTTTGFGVALRSSLVRSAVLE HHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHH VMGAHAAGDAHRRAADVVDDPVRRLRHLVAATPVPDAALADQVDAMARERGAEGAWAEAA HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH SLFREAGRLTPDALLRDDRLTRSVDALVAAGDTAGAAALTPAVESLRETPLRDAALAYLA HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH IVRGRAAEADVRLRRAWGIVNADRDPEAAALIAGRYVLHALMRCRGAEIVQWADRAIELS HHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEC GDDSPAGVEAAAIRGLGLSAVGHSARAAAAYDELSDRIRYGAQAQRIAMGRGWLQLAGDD CCCCCCCCHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCC LDGARSSLEGAVSTTELGGSARIALWALGWLARVQFLTGDWDQALSTVERGRLTAASSGI CHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECCCCE VLVTPLLEWTATQIHALRGDFEAAQAAVRTADTVTQGYEMMHLATFLARAQVAEAEADYA EEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GVRRALEPLRRMSQHITTEPALWPWADVLANAMVLDGQPDAADAFLGPHEQRADRRAQRS HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCEEECCCCCCCHHHCCCCHHHHHHHHHHH TRARLGYARGRILGAAGDINAARRAFDESLALLDGLPLRYDLARVNFAYGQTLRRAGKRR HHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCC DADAVISTARDLYLSLGAQTYVARCERELKAGGVHVVRGPRGHAELTPQEDAVTTLVAQG CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHC LSNREVAAELYVSPKTVQYHLTRIYAKLGVRSRTELAALRS CCCCCHHHHEEECCCHHHHHHHHHHHHHCCCCHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]