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The map label for this gene is ucpA [H]

Identifier: 119867433

GI number: 119867433

Start: 1484592

End: 1485446

Strand: Reverse

Name: ucpA [H]

Synonym: Mkms_1383

Alternate gene names: 119867433

Gene position: 1485446-1484592 (Counterclockwise)

Preceding gene: 119867434

Following gene: 119867430

Centisome position: 25.89

GC content: 67.02

Gene sequence:

>855_bases
ATGGCCGACAAACCCCTGAGCGGGAAAACCATGTTCATCTCCGGCGCGAGCCGCGGTATCGGCTTGGCCATCGCCAAGCG
CGTCGCCGCCGACGGCGCCAACATCGCTCTGGTCGCCAAGACCGCCGAACCGCATCCCAAACTGCCCGGCACGATCTACA
CCGCGGCCGAGGAGATCGAGGCGGCCGGCGGTCAGGCGCTGCCCATCGTCGGTGACATCCGCGACGGTGATTCGGTCACC
GCCGCCGTCGCCAAGACCGTGGAGCAGTTCGGCGGCATCGACATCTGCGTCAACAACGCGTCGGCGATCAACCTGGGCTC
GGTCGAGGAGGTGCCGCTCAAACGCTTCGATCTGATGAACGGCATCCAGGTGCGCGGCACCTACGCCGTCACTCAGGCCT
GCATCCCGCACATGAAGGGCCGCGACAACCCGCACATCCTCACGCTGTCCCCGCCGATCCGGCTGGAGCCGCAGTGGTTG
ACACCGACCGCCTACATGATGGCGAAATTCGGAATGACGTTGTGCGCGTTGGGTATCGCCGAAGAGATGCGCGAGGCGGG
GATCGCGTCGAACACCCTGTGGCCGCGCACGATGGTGGCGACCGCCGCAGTGCAGAACCTGCTCGGCGGCGACGAGGCGA
TGGCCCGCGCCCGCAAACCCGAGGTGTATTCCGATGCGGCCTATGCGGTGCTGACCAAACCGTCGTCCTACACCGGGCAC
AGCCTGCTGTGCGAGGACGTGCTGCTCGAGGCCGGCGTCACGGATCTGTCGGCCTACGACTGCATCCGGGGCTCCGAGCT
CGGAGTCGACCTGTGGGTCGACTCCCCCAACCCGCCGGGTTACGAAGGGCCCTGA

Upstream 100 bases:

>100_bases
GCACACGCCGTGCGGGCCCATTCGCCGCTGGTCGAACGTGTTCTGGAGGTCTTGCGTGGAGTCGCCCGAACCCAGCAGCG
GCCCGACATAGGCTGAGACC

Downstream 100 bases:

>100_bases
GGCCACACATTGCGCCCACGGTCGTGGATTCGGCTCGCGCACTGCCGTGGGCGCAATCTTCGGGCGCGCAAGCAGAGTCA
GTCGGCCTGGTAGACGATCC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MADKPLSGKTMFISGASRGIGLAIAKRVAADGANIALVAKTAEPHPKLPGTIYTAAEEIEAAGGQALPIVGDIRDGDSVT
AAVAKTVEQFGGIDICVNNASAINLGSVEEVPLKRFDLMNGIQVRGTYAVTQACIPHMKGRDNPHILTLSPPIRLEPQWL
TPTAYMMAKFGMTLCALGIAEEMREAGIASNTLWPRTMVATAAVQNLLGGDEAMARARKPEVYSDAAYAVLTKPSSYTGH
SLLCEDVLLEAGVTDLSAYDCIRGSELGVDLWVDSPNPPGYEGP

Sequences:

>Translated_284_residues
MADKPLSGKTMFISGASRGIGLAIAKRVAADGANIALVAKTAEPHPKLPGTIYTAAEEIEAAGGQALPIVGDIRDGDSVT
AAVAKTVEQFGGIDICVNNASAINLGSVEEVPLKRFDLMNGIQVRGTYAVTQACIPHMKGRDNPHILTLSPPIRLEPQWL
TPTAYMMAKFGMTLCALGIAEEMREAGIASNTLWPRTMVATAAVQNLLGGDEAMARARKPEVYSDAAYAVLTKPSSYTGH
SLLCEDVLLEAGVTDLSAYDCIRGSELGVDLWVDSPNPPGYEGP
>Mature_283_residues
ADKPLSGKTMFISGASRGIGLAIAKRVAADGANIALVAKTAEPHPKLPGTIYTAAEEIEAAGGQALPIVGDIRDGDSVTA
AVAKTVEQFGGIDICVNNASAINLGSVEEVPLKRFDLMNGIQVRGTYAVTQACIPHMKGRDNPHILTLSPPIRLEPQWLT
PTAYMMAKFGMTLCALGIAEEMREAGIASNTLWPRTMVATAAVQNLLGGDEAMARARKPEVYSDAAYAVLTKPSSYTGHS
LLCEDVLLEAGVTDLSAYDCIRGSELGVDLWVDSPNPPGYEGP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254986, Length=270, Percent_Identity=50.3703703703704, Blast_Score=274, Evalue=8e-74,
Organism=Homo sapiens, GI209862901, Length=274, Percent_Identity=25.9124087591241, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI19923983, Length=274, Percent_Identity=25.9124087591241, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4504505, Length=218, Percent_Identity=26.605504587156, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082100, Length=219, Percent_Identity=32.4200913242009, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789208, Length=203, Percent_Identity=26.1083743842365, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=268, Percent_Identity=51.4925373134328, Blast_Score=278, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17558628, Length=270, Percent_Identity=52.2222222222222, Blast_Score=274, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI17544670, Length=274, Percent_Identity=28.8321167883212, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=212, Percent_Identity=27.3584905660377, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357673, Length=278, Percent_Identity=52.158273381295, Blast_Score=299, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=30.3664921465969, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=31.0880829015544, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571526, Length=193, Percent_Identity=30.5699481865285, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29882; Mature: 29750

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKPLSGKTMFISGASRGIGLAIAKRVAADGANIALVAKTAEPHPKLPGTIYTAAEEIE
CCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEHHHHHHH
AAGGQALPIVGDIRDGDSVTAAVAKTVEQFGGIDICVNNASAINLGSVEEVPLKRFDLMN
HCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCHHHHHHCC
GIQVRGTYAVTQACIPHMKGRDNPHILTLSPPIRLEPQWLTPTAYMMAKFGMTLCALGIA
CEEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
EEMREAGIASNTLWPRTMVATAAVQNLLGGDEAMARARKPEVYSDAAYAVLTKPSSYTGH
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEECCCCCCCC
SLLCEDVLLEAGVTDLSAYDCIRGSELGVDLWVDSPNPPGYEGP
HHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ADKPLSGKTMFISGASRGIGLAIAKRVAADGANIALVAKTAEPHPKLPGTIYTAAEEIE
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEHHHHHHH
AAGGQALPIVGDIRDGDSVTAAVAKTVEQFGGIDICVNNASAINLGSVEEVPLKRFDLMN
HCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCHHHHHHCC
GIQVRGTYAVTQACIPHMKGRDNPHILTLSPPIRLEPQWLTPTAYMMAKFGMTLCALGIA
CEEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
EEMREAGIASNTLWPRTMVATAAVQNLLGGDEAMARARKPEVYSDAAYAVLTKPSSYTGH
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEECCCCCCCC
SLLCEDVLLEAGVTDLSAYDCIRGSELGVDLWVDSPNPPGYEGP
HHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]