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The map label for this gene is sugE [H]

Identifier: 119867281

GI number: 119867281

Start: 1317966

End: 1318289

Strand: Reverse

Name: sugE [H]

Synonym: Mkms_1231

Alternate gene names: 119867281

Gene position: 1318289-1317966 (Counterclockwise)

Preceding gene: 119867283

Following gene: 119867277

Centisome position: 22.98

GC content: 66.67

Gene sequence:

>324_bases
GTGTCCTGGCTGATCCTGATCATCTCGGGTGCATTCGAGGCGGTGTGGGCGGTCGCCCTGAGCAGATCCGAAGGGTTCAC
CCGGCCTGTCCCGACCGTGGTCTTCGCTGTGGCCGTGGTGATCTCGATGGGCGGTCTCGGCTATGCGCTACGCGATCTCC
CCGTCGGCACCGGTTACGCCGTGTGGGTGGGCATCGGCGCGGCGCTCACGGTGGCGTATTCGTTGGTGACCGGCGAGGAG
AGCGCATCGGTGATCAAGGTGGCGCTCCTGCTGGGCATCGTCGGCTGCGTTGTCGGCCTGCAACTGGTCAGCCAGGGCCA
CTAG

Upstream 100 bases:

>100_bases
CGACGCTACCGCTTTGCTACCGTGGCGATGTCACCAGTTGACACCGGACGAGCGGCACCGTACCCGGCCAGCGACAAGAC
GGCGCTCACGGAGGTGTCCT

Downstream 100 bases:

>100_bases
CGCCGGCGCAGTCGCGAAACCCCAACGGCGCCAAGTGCTCCCACAGCCGCGGCGGCCATCGCTCCCGGCACGCCGACACC
CTCGCGCACCTGCACCCGCG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MSWLILIISGAFEAVWAVALSRSEGFTRPVPTVVFAVAVVISMGGLGYALRDLPVGTGYAVWVGIGAALTVAYSLVTGEE
SASVIKVALLLGIVGCVVGLQLVSQGH

Sequences:

>Translated_107_residues
MSWLILIISGAFEAVWAVALSRSEGFTRPVPTVVFAVAVVISMGGLGYALRDLPVGTGYAVWVGIGAALTVAYSLVTGEE
SASVIKVALLLGIVGCVVGLQLVSQGH
>Mature_106_residues
SWLILIISGAFEAVWAVALSRSEGFTRPVPTVVFAVAVVISMGGLGYALRDLPVGTGYAVWVGIGAALTVAYSLVTGEES
ASVIKVALLLGIVGCVVGLQLVSQGH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=105, Percent_Identity=44.7619047619048, Blast_Score=87, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10945; Mature: 10814

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS01159 WW_DOMAIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLILIISGAFEAVWAVALSRSEGFTRPVPTVVFAVAVVISMGGLGYALRDLPVGTGYA
CCEEEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHH
VWVGIGAALTVAYSLVTGEESASVIKVALLLGIVGCVVGLQLVSQGH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SWLILIISGAFEAVWAVALSRSEGFTRPVPTVVFAVAVVISMGGLGYALRDLPVGTGYA
CEEEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHH
VWVGIGAALTVAYSLVTGEESASVIKVALLLGIVGCVVGLQLVSQGH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]