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The map label for this gene is baeS [H]

Identifier: 119855087

GI number: 119855087

Start: 211101

End: 212246

Strand: Reverse

Name: baeS [H]

Synonym: Mkms_5699

Alternate gene names: 119855087

Gene position: 212246-211101 (Counterclockwise)

Preceding gene: 119855088

Following gene: 119855085

Centisome position: 70.26

GC content: 66.49

Gene sequence:

>1146_bases
ATGAGGACAGACACGAGCATTCAACCCAGGTCGCGGCGCAGTCCTGGAGTCGGGGCGCGACTCCTGCTGGCGCAAGCCTT
GGTGCTCCTCGCCGGCGGCGCAACCACCGGGGTCGTCGCCGTCATCGTCGGTCCACCGCTGTTCCGAGAACACCTGAACC
GCGCCGGACTTCCTCACTCATCCAATGAACAGTTCCACGCCGAGGAGGCCTACCGGTACGCCACCGCAATCTCCATCGCG
GTGGCGATCGGCGTAGCCGCATTGACCGCCCTGTTTGTGACCTGGTACTTCAGCCGTCGCCTGCAGCACTCCATCGCCGA
GGTCGCATCGGCCGCCACTGCAGTCGCCGACGGCCGCTATGACATCCGTGTGTCGCCGCTGCGCTTGGGGGAGGATTTCG
CGAACCTGTCCCGCGCGTTCAATCGGATGTCCGAACGGCTCGAATCGGTCGAGACCACCCGGCGCCAACTCTTCGGTGAC
CTCGCCCACGAGATTAGGACACCCGTCTCGGTACTCAAGGCCTACATCGAGGCCGTCGAGGACGGAGTGAAAACCCTTGA
CCCCGAGACGGTTGCCGTGCTCAACGATCAAGCCAGCCGGCTGGTGCGCTTCTCCGATGACTTCGCCGCGCTCGCTCAAG
CCGAGGAAGGTCCCGGCGCGGTCACACCGCAGTGGATCGACCCCCAGGCCGCGATCGTCACCACCGTGTCTGCCGCAGCC
GACCGATACGCCCAGAAGGATGTCGCGCTGACCTTCGATGCCGCGAACCCGCTGCCCGAGGTGTGGGTAGACCCTCTGCG
CCTCGCACAGGTGATCGGGAACCTTCTCGACAACGCTCTGCGCCACACCCCCGCGCGAGGCCGCGTCGAGGTCGACGCGG
CGGCAAAGCCCGGCGAAGTGATCATCACCGTGCGCGACAATGGTGATGGCATCGCTGCCGAGCACCTCCCGCACGTGTTC
GAACGCTTCTACCGCGCCGATGTGGCCCGCGATCGAAGCCACGGCGGCGCGGGGATCGGGTTGGCCATCGCCAAAGCACT
CACCGAAGCCCACAGCGGCCGCATCACTGCGGCCAGCCGCGGACCAGGCCTGGGCAGCACCTTCACCATCGAGCTACCCG
CACGCACGGACCGCCATGACCACTAA

Upstream 100 bases:

>100_bases
TCCACATCGGACATCTGCGCCGCAAATTGTCGGATGACCCCGCCGGTCCCCGCTACGTGATCACCGTCCGCGGAGTCGGA
TACCGAATGGGAAGCGGCCA

Downstream 100 bases:

>100_bases
TCGAACTCGACAACGCTGTCATGAAACATGACTCGCGCGACACGCAGCCATGCCCTGACTTCTACAACGAGGCCAGGATC
TTGTTCATGGTGTCGATCTC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MRTDTSIQPRSRRSPGVGARLLLAQALVLLAGGATTGVVAVIVGPPLFREHLNRAGLPHSSNEQFHAEEAYRYATAISIA
VAIGVAALTALFVTWYFSRRLQHSIAEVASAATAVADGRYDIRVSPLRLGEDFANLSRAFNRMSERLESVETTRRQLFGD
LAHEIRTPVSVLKAYIEAVEDGVKTLDPETVAVLNDQASRLVRFSDDFAALAQAEEGPGAVTPQWIDPQAAIVTTVSAAA
DRYAQKDVALTFDAANPLPEVWVDPLRLAQVIGNLLDNALRHTPARGRVEVDAAAKPGEVIITVRDNGDGIAAEHLPHVF
ERFYRADVARDRSHGGAGIGLAIAKALTEAHSGRITAASRGPGLGSTFTIELPARTDRHDH

Sequences:

>Translated_381_residues
MRTDTSIQPRSRRSPGVGARLLLAQALVLLAGGATTGVVAVIVGPPLFREHLNRAGLPHSSNEQFHAEEAYRYATAISIA
VAIGVAALTALFVTWYFSRRLQHSIAEVASAATAVADGRYDIRVSPLRLGEDFANLSRAFNRMSERLESVETTRRQLFGD
LAHEIRTPVSVLKAYIEAVEDGVKTLDPETVAVLNDQASRLVRFSDDFAALAQAEEGPGAVTPQWIDPQAAIVTTVSAAA
DRYAQKDVALTFDAANPLPEVWVDPLRLAQVIGNLLDNALRHTPARGRVEVDAAAKPGEVIITVRDNGDGIAAEHLPHVF
ERFYRADVARDRSHGGAGIGLAIAKALTEAHSGRITAASRGPGLGSTFTIELPARTDRHDH
>Mature_381_residues
MRTDTSIQPRSRRSPGVGARLLLAQALVLLAGGATTGVVAVIVGPPLFREHLNRAGLPHSSNEQFHAEEAYRYATAISIA
VAIGVAALTALFVTWYFSRRLQHSIAEVASAATAVADGRYDIRVSPLRLGEDFANLSRAFNRMSERLESVETTRRQLFGD
LAHEIRTPVSVLKAYIEAVEDGVKTLDPETVAVLNDQASRLVRFSDDFAALAQAEEGPGAVTPQWIDPQAAIVTTVSAAA
DRYAQKDVALTFDAANPLPEVWVDPLRLAQVIGNLLDNALRHTPARGRVEVDAAAKPGEVIITVRDNGDGIAAEHLPHVF
ERFYRADVARDRSHGGAGIGLAIAKALTEAHSGRITAASRGPGLGSTFTIELPARTDRHDH

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=34.0501792114695, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786783, Length=296, Percent_Identity=31.7567567567568, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=31.8965517241379, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1787894, Length=297, Percent_Identity=26.5993265993266, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=31.6964285714286, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790346, Length=270, Percent_Identity=28.8888888888889, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=26.7206477732794, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=26.7206477732794, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789149, Length=344, Percent_Identity=24.7093023255814, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789808, Length=287, Percent_Identity=26.4808362369338, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=285, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=24.7863247863248, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=337, Percent_Identity=24.9258160237389, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787374, Length=233, Percent_Identity=27.8969957081545, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=26.1261261261261, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=27.6859504132231, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788279, Length=313, Percent_Identity=22.3642172523962, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790551, Length=346, Percent_Identity=24.2774566473988, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790300, Length=299, Percent_Identity=29.0969899665552, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40931; Mature: 40931

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDTSIQPRSRRSPGVGARLLLAQALVLLAGGATTGVVAVIVGPPLFREHLNRAGLPHS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCEEEEEECCHHHHHHHHHCCCCCC
SNEQFHAEEAYRYATAISIAVAIGVAALTALFVTWYFSRRLQHSIAEVASAATAVADGRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
DIRVSPLRLGEDFANLSRAFNRMSERLESVETTRRQLFGDLAHEIRTPVSVLKAYIEAVE
EEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
DGVKTLDPETVAVLNDQASRLVRFSDDFAALAQAEEGPGAVTPQWIDPQAAIVTTVSAAA
HHHHHCCCCCEEEECHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
DRYAQKDVALTFDAANPLPEVWVDPLRLAQVIGNLLDNALRHTPARGRVEVDAAAKPGEV
HHHHHCCEEEEECCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCE
IITVRDNGDGIAAEHLPHVFERFYRADVARDRSHGGAGIGLAIAKALTEAHSGRITAASR
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCC
GPGLGSTFTIELPARTDRHDH
CCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MRTDTSIQPRSRRSPGVGARLLLAQALVLLAGGATTGVVAVIVGPPLFREHLNRAGLPHS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCEEEEEECCHHHHHHHHHCCCCCC
SNEQFHAEEAYRYATAISIAVAIGVAALTALFVTWYFSRRLQHSIAEVASAATAVADGRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
DIRVSPLRLGEDFANLSRAFNRMSERLESVETTRRQLFGDLAHEIRTPVSVLKAYIEAVE
EEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
DGVKTLDPETVAVLNDQASRLVRFSDDFAALAQAEEGPGAVTPQWIDPQAAIVTTVSAAA
HHHHHCCCCCEEEECHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
DRYAQKDVALTFDAANPLPEVWVDPLRLAQVIGNLLDNALRHTPARGRVEVDAAAKPGEV
HHHHHCCEEEEECCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCE
IITVRDNGDGIAAEHLPHVFERFYRADVARDRSHGGAGIGLAIAKALTEAHSGRITAASR
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEECCC
GPGLGSTFTIELPARTDRHDH
CCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]