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The map label for this gene is yggV [C]

Identifier: 119900253

GI number: 119900253

Start: 4345038

End: 4345634

Strand: Direct

Name: yggV [C]

Synonym: azo3964

Alternate gene names: 119900253

Gene position: 4345038-4345634 (Clockwise)

Preceding gene: 119900252

Following gene: 119900254

Centisome position: 99.29

GC content: 71.69

Gene sequence:

>597_bases
ATGAGCAAACGACTCGTCCTTGCCAGCAACAACGCCAAGAAAGCCGCCGAGATGCAGGCCCTGCTCGCGCCGCTCGGCAT
CGAGGTGGTGGCGCAGGGCGCGCTTGGAGTTTCGGAGGCCGAGGAGCCGCACGGCACCTTCGTCGAGAACGCGCTCGCCA
AGGCGCGCCATGCCGCGGCGGCCACCGGCCTGCCCGCGGTGGCCGACGACTCCGGCCTGTGCGTGAGCGCGCTGGGCGGC
GCACCGGGCGTGCTTTCCGCGCGCTTTGCCGGCGAACCGAAGTCCGACGCGCGCAACAACGCGCTGCTGCTGGACAAGCT
GGCCGGGGTCGCGGACCGCAGCGCCTACTTCTACTCGGCGGTGGTGCTGGTGCGCCACGCCGGCGATCCGCGCCCGCTGA
TCGCCGACGGTGAATGGCACGGCACCATCCTCGAAGCGGCGCGCGGCGAGGGCGGCTTTGGCTACGACCCGCTGTTCTGG
CTGCCGGAACTCGCGCAGACCGCGGCCGAACTCGACGCCGCGCTGAAGAACACCCTCTCCCACCGCGGCGCCGCCATGCG
CCATCTGCTCGACCGCCTCAAGACCCACCCGCTGTGA

Upstream 100 bases:

>100_bases
CTTCTCGCGCACCGAACTCAACGCCCTGATCGACCTCGCCGAAGCCGGCATCGGCCGCCTCGTGGAACTGCAGAAGGCGG
CGCTGGCGGGAGCCTGACGC

Downstream 100 bases:

>100_bases
ACGAACGCCGCGTCATCCCGCTGACGCCGGCGCCGGCAGCGGCGGCCGTCGTCCTTCCCGAGCGCCCGCAGCTCAGCGCG
CCGCCGCCGCTCGCGCTGTA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSKRLVLASNNAKKAAEMQALLAPLGIEVVAQGALGVSEAEEPHGTFVENALAKARHAAAATGLPAVADDSGLCVSALGG
APGVLSARFAGEPKSDARNNALLLDKLAGVADRSAYFYSAVVLVRHAGDPRPLIADGEWHGTILEAARGEGGFGYDPLFW
LPELAQTAAELDAALKNTLSHRGAAMRHLLDRLKTHPL

Sequences:

>Translated_198_residues
MSKRLVLASNNAKKAAEMQALLAPLGIEVVAQGALGVSEAEEPHGTFVENALAKARHAAAATGLPAVADDSGLCVSALGG
APGVLSARFAGEPKSDARNNALLLDKLAGVADRSAYFYSAVVLVRHAGDPRPLIADGEWHGTILEAARGEGGFGYDPLFW
LPELAQTAAELDAALKNTLSHRGAAMRHLLDRLKTHPL
>Mature_197_residues
SKRLVLASNNAKKAAEMQALLAPLGIEVVAQGALGVSEAEEPHGTFVENALAKARHAAAATGLPAVADDSGLCVSALGGA
PGVLSARFAGEPKSDARNNALLLDKLAGVADRSAYFYSAVVLVRHAGDPRPLIADGEWHGTILEAARGEGGFGYDPLFWL
PELAQTAAELDAALKNTLSHRGAAMRHLLDRLKTHPL

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=192, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=49.7435897435897, Blast_Score=193, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17556833, Length=195, Percent_Identity=29.7435897435897, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19920712, Length=188, Percent_Identity=31.3829787234043, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 20588; Mature: 20456

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRLVLASNNAKKAAEMQALLAPLGIEVVAQGALGVSEAEEPHGTFVENALAKARHAAA
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ATGLPAVADDSGLCVSALGGAPGVLSARFAGEPKSDARNNALLLDKLAGVADRSAYFYSA
HCCCCCCCCCCCCEEEECCCCCCCEEHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHH
VVLVRHAGDPRPLIADGEWHGTILEAARGEGGFGYDPLFWLPELAQTAAELDAALKNTLS
HHHHHHCCCCCCEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HRGAAMRHLLDRLKTHPL
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKRLVLASNNAKKAAEMQALLAPLGIEVVAQGALGVSEAEEPHGTFVENALAKARHAAA
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ATGLPAVADDSGLCVSALGGAPGVLSARFAGEPKSDARNNALLLDKLAGVADRSAYFYSA
HCCCCCCCCCCCCEEEECCCCCCCEEHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHH
VVLVRHAGDPRPLIADGEWHGTILEAARGEGGFGYDPLFWLPELAQTAAELDAALKNTLS
HHHHHHCCCCCCEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HRGAAMRHLLDRLKTHPL
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA