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The map label for this gene is yggW [H]

Identifier: 119900254

GI number: 119900254

Start: 4345631

End: 4346854

Strand: Direct

Name: yggW [H]

Synonym: azo3965

Alternate gene names: 119900254

Gene position: 4345631-4346854 (Clockwise)

Preceding gene: 119900253

Following gene: 119900260

Centisome position: 99.31

GC content: 70.67

Gene sequence:

>1224_bases
GTGAACGAACGCCGCGTCATCCCGCTGACGCCGGCGCCGGCAGCGGCGGCCGTCGTCCTTCCCGAGCGCCCGCAGCTCAG
CGCGCCGCCGCCGCTCGCGCTGTACGTGCATTTCCCGTGGTGCGTGCGCAAGTGCCCGTACTGCGACTTCAACTCGCACG
CCCCGCGCGGTGAGACCGCCATTCCGGAAGAGGCGTGGGCCGCAGCCGTGGTGGCCGACCTCGAAGCCGCCCTGCCGCAG
GTGTGGGGGCGTCGGGTGCACAGCATCTTCATCGGTGGCGGCACGCCCAGCCTGATGTCGGCACCGGTGCTCGACCGCCT
GCTCACCGACATCCGCATGCGCCTGCCGCTCGACCCGATGGCGGAGATCACGCTGGAGGCCAATCCCGGCACGGTGGAAG
CGGCCCGCTTCCGCGATTTCCGCGCCGCCGGCGTCAACCGCCTGTCGCTCGGCGTCCAGAGCTTCGACGACGCCATGCTC
CTCCGCCTCGGCCGCATCCACGGCAGCGACGAAGCGAAGCGTGCGATCGAAGGCGCACTCGCGCACTTCGAGCGGGTAAA
CATCGACCTGATGTACGCGCTACCGCAGCAAGGGCTGGACGCGGCGCTCGCCGACCTCGACACCGCGCTCGGCTTCGGCG
TCACGCATCTGTCCTGCTACCACCTGACGCTGGAGCCGAACACGCCCTTCGCCCACGATCCGCCGCCGCTGCCGGACGAC
GACAGCGCCGCCGACATGCAGGACGCGATCGAGGCGCGGCTGGCGGCCGCGGGCTTCCGCCACTACGAAACCTCCGCCTT
CGCCCGGCCGGGGCAGGAATGCCGCCACAACCTCAACTACTGGCAGTTCGGCGACTACCTCGGGATCGGCCCCGGCGCCC
ACGGCAAGCTCTCCAACCATGAAGGCATCGTGCGCGAGATGCGCCACAAGCATCCGCAGCGCTATCTGGAAGGCGCGGCG
CGCGGCGACTTCGTGCAGGAACGGCGGTCGGTGACGGTCGCCGAGCTGCCGTTCGAATTCATGATGAACGCGCTGCGGCT
GACCGGCGGTTTTCCGCTCGCGCTGTTCGCCGCGCGCACCGGGCTGCCGCTGGCCGCGGTGGAAGCGCGCCTGCGTGCGG
CGCGCCAGGACGGCCTGCTCGAGATCGACGCTGACAGCGTGCGCCCGACCGAGCGCGGACGCCACTTCCTCAACGACCTT
CTGCAGCGTTTCCTGGACGACTGA

Upstream 100 bases:

>100_bases
CGCAGACCGCGGCCGAACTCGACGCCGCGCTGAAGAACACCCTCTCCCACCGCGGCGCCGCCATGCGCCATCTGCTCGAC
CGCCTCAAGACCCACCCGCT

Downstream 100 bases:

>100_bases
GCGCCGCTCAGATCACCTGCAGCAGCTTGGTCCGCAGCGCCTCGGCCTCGCGCCGGCCCTCGCGCGAGCTGACCAGCGCG
TGATACCACTCGTCGAACAG

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNERRVIPLTPAPAAAAVVLPERPQLSAPPPLALYVHFPWCVRKCPYCDFNSHAPRGETAIPEEAWAAAVVADLEAALPQ
VWGRRVHSIFIGGGTPSLMSAPVLDRLLTDIRMRLPLDPMAEITLEANPGTVEAARFRDFRAAGVNRLSLGVQSFDDAML
LRLGRIHGSDEAKRAIEGALAHFERVNIDLMYALPQQGLDAALADLDTALGFGVTHLSCYHLTLEPNTPFAHDPPPLPDD
DSAADMQDAIEARLAAAGFRHYETSAFARPGQECRHNLNYWQFGDYLGIGPGAHGKLSNHEGIVREMRHKHPQRYLEGAA
RGDFVQERRSVTVAELPFEFMMNALRLTGGFPLALFAARTGLPLAAVEARLRAARQDGLLEIDADSVRPTERGRHFLNDL
LQRFLDD

Sequences:

>Translated_407_residues
MNERRVIPLTPAPAAAAVVLPERPQLSAPPPLALYVHFPWCVRKCPYCDFNSHAPRGETAIPEEAWAAAVVADLEAALPQ
VWGRRVHSIFIGGGTPSLMSAPVLDRLLTDIRMRLPLDPMAEITLEANPGTVEAARFRDFRAAGVNRLSLGVQSFDDAML
LRLGRIHGSDEAKRAIEGALAHFERVNIDLMYALPQQGLDAALADLDTALGFGVTHLSCYHLTLEPNTPFAHDPPPLPDD
DSAADMQDAIEARLAAAGFRHYETSAFARPGQECRHNLNYWQFGDYLGIGPGAHGKLSNHEGIVREMRHKHPQRYLEGAA
RGDFVQERRSVTVAELPFEFMMNALRLTGGFPLALFAARTGLPLAAVEARLRAARQDGLLEIDADSVRPTERGRHFLNDL
LQRFLDD
>Mature_407_residues
MNERRVIPLTPAPAAAAVVLPERPQLSAPPPLALYVHFPWCVRKCPYCDFNSHAPRGETAIPEEAWAAAVVADLEAALPQ
VWGRRVHSIFIGGGTPSLMSAPVLDRLLTDIRMRLPLDPMAEITLEANPGTVEAARFRDFRAAGVNRLSLGVQSFDDAML
LRLGRIHGSDEAKRAIEGALAHFERVNIDLMYALPQQGLDAALADLDTALGFGVTHLSCYHLTLEPNTPFAHDPPPLPDD
DSAADMQDAIEARLAAAGFRHYETSAFARPGQECRHNLNYWQFGDYLGIGPGAHGKLSNHEGIVREMRHKHPQRYLEGAA
RGDFVQERRSVTVAELPFEFMMNALRLTGGFPLALFAARTGLPLAAVEARLRAARQDGLLEIDADSVRPTERGRHFLNDL
LQRFLDD

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=283, Percent_Identity=42.756183745583, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=50.2645502645503, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI87082341, Length=409, Percent_Identity=26.161369193154, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44817; Mature: 44817

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERRVIPLTPAPAAAAVVLPERPQLSAPPPLALYVHFPWCVRKCPYCDFNSHAPRGETA
CCCCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEECHHHHHCCCCCCCCCCCCCCCCC
IPEEAWAAAVVADLEAALPQVWGRRVHSIFIGGGTPSLMSAPVLDRLLTDIRMRLPLDPM
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AEITLEANPGTVEAARFRDFRAAGVNRLSLGVQSFDDAMLLRLGRIHGSDEAKRAIEGAL
CEEEEECCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AHFERVNIDLMYALPQQGLDAALADLDTALGFGVTHLSCYHLTLEPNTPFAHDPPPLPDD
HHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCC
DSAADMQDAIEARLAAAGFRHYETSAFARPGQECRHNLNYWQFGDYLGIGPGAHGKLSNH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEECCCCCCCCCCCCCCCCCC
EGIVREMRHKHPQRYLEGAARGDFVQERRSVTVAELPFEFMMNALRLTGGFPLALFAART
HHHHHHHHHHCHHHHHHHHHCCHHHHHHHCCCHHHCCHHHHHHHHHHCCCCHHHHHHHHC
GLPLAAVEARLRAARQDGLLEIDADSVRPTERGRHFLNDLLQRFLDD
CCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNERRVIPLTPAPAAAAVVLPERPQLSAPPPLALYVHFPWCVRKCPYCDFNSHAPRGETA
CCCCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEECHHHHHCCCCCCCCCCCCCCCCC
IPEEAWAAAVVADLEAALPQVWGRRVHSIFIGGGTPSLMSAPVLDRLLTDIRMRLPLDPM
CCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AEITLEANPGTVEAARFRDFRAAGVNRLSLGVQSFDDAMLLRLGRIHGSDEAKRAIEGAL
CEEEEECCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AHFERVNIDLMYALPQQGLDAALADLDTALGFGVTHLSCYHLTLEPNTPFAHDPPPLPDD
HHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCC
DSAADMQDAIEARLAAAGFRHYETSAFARPGQECRHNLNYWQFGDYLGIGPGAHGKLSNH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEECCCCCCCCCCCCCCCCCC
EGIVREMRHKHPQRYLEGAARGDFVQERRSVTVAELPFEFMMNALRLTGGFPLALFAART
HHHHHHHHHHCHHHHHHHHHCCHHHHHHHCCCHHHCCHHHHHHHHHHCCCCHHHHHHHHC
GLPLAAVEARLRAARQDGLLEIDADSVRPTERGRHFLNDLLQRFLDD
CCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]