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The map label for this gene is aer [H]

Identifier: 119900226

GI number: 119900226

Start: 4313372

End: 4315009

Strand: Direct

Name: aer [H]

Synonym: azo3937

Alternate gene names: 119900226

Gene position: 4313372-4315009 (Clockwise)

Preceding gene: 119900214

Following gene: 119900235

Centisome position: 98.57

GC content: 69.17

Gene sequence:

>1638_bases
ATGCGCGCCCGCAGTTCGTACACCAACGAAATCGAGACCGTCATCCCCGACGGCGCTTTCATCTACTCGCGTACCGACCT
CAAGGGGCGCATCGAGGAGGCCAACGAGGCCTTTGCCGAGATCAGCGGCTATACGCGCGAGGACATGATCGGCAAGCCGC
ACAACATGGTCCGCCATCCCGACATGCCGGCGGAGGCCTTCAAGGACATGTGGTCCGACCTGGTGGCGGGCCGGCCGTGG
CGGGGGCTGGTGAAGAACCGGCGCAGCGACGGCGGCTACTACTGGGTGGTGGCCAACGCCTCGCCAGTACGCGAGGGCGG
CCGGATTGTCGGTTACCAGTCGGTGCGCTCGCGCCCGACGCGCGAAGAGGTTGCGGCGGCCGAAGCCGCCTACAAGCGCA
TCCGCGAAGGCGACCGCTCGATCAAGGTCTATCACGGCCGCGTGGTGGCCAACCGGCCAGCGTGGATCAACGCCGCCGTG
TCGCTGCGGGCGCAGATGAACGCGGTGGGCGTGCTCGCCGTGTTGCAGGCCCTGCTGATGGTGGTCGAAGGCTTCACCGC
GATCGAGGTTCCGGCGACGCTGATGGCCCTGGTGGCGGTGCCCTCGCTGCTCTACGCGCTGTATTTCCTGCTGATCTACG
CGCCGCACGTCCAGCGCGACCTCGGCGCCACCGCGGCCTGGCTGGAAAACATCCTGACCACCGGCGACCTGCGGCACCGC
TTCGACCTCAAGCGGCGCGACGTGATCGGCGCGCTGGCACGCCGTGCCGACAAGGTGGTGTCCTCGGTGCAGGCCACGCT
GCAGGGCATGACGGAGGTGTCGGTGCAGGTCGAGCACGCGGCCGGGCAGGTGGGTAGCCGGGTGCACGACGTGCGCCTGT
CGGCGCAGACGCAGAGCGAAGCGGCGAGTTCGGCGGCGGCGTCGATCGAAGAGGTCACGGTGTCGATCGGCGAGGTCGCG
GCGCATGCCGCGTCGACCCGCGAGGTGGCGGAAGAAACCAGCCGCGTGTCGGACGAAGGCGCGCGGATCACGCGCGACGC
GAGCCGCAACATCCAGTCGCTGGCCGACCGCGTCGGGGTGTCGGCCGAGCAGCTCGAAACCCTGGGCAAGCGTTCGGACG
AGATCGGCCGCATCACGGGCGTGATCCGCGAGATCGCCGACCAGACCAACCTGCTCGCGCTCAACGCCGCGATCGAGGCC
GCGCGCGCCGGCGAGCAGGGGCGCGGCTTCGCGGTGGTGGCCGACGAGGTGCGCAAGCTCGCCGAACGCACCGGCCAGGC
GACGCGTGAAATCGGCGAGATGATCGACACCATCCGCAGCGAAACGCAGCAGGCGGTCGACACCATGCGCGCGGGCGCCA
CCCAAGTGGGCGAAGGGGTGGAGCGCGTGGGCGCGGCGGAAGAATCGCTGAACCGCATCAATGCCGAGATGGCGGTCACG
ATGGAGCGCGTGACCGAAATCTCGCACGCCTCGGGGGAGCAACAGGTGGCGTTGCAGGACCTCGCCCGCCATATCGAGCA
GGTCGCGTCGATGACCGAGCAGAACGTGGCCGTGGTGGCGGACACCGAGGACATGGTGAACCGGCTGGAAGCGGTGGTGG
ACCGCATGCGCAAGGCCGTGGGGCAGTACGCGGTGTAA

Upstream 100 bases:

>100_bases
GACACAACTAAAGTCGTGGGCACGAAACGTGCTCCCCATACTTCCTCCAGCCCCGCCTCAGAGAGATCCGACGGCCCTGC
GCCGCGGACGGGAGAACAGC

Downstream 100 bases:

>100_bases
GAAGGCCCCCACGCTTGCCACTGCGTGGCGGCGAGGAGTGCCGGCTTTGCACAGCCGACCCGTTCCGCGGGCGCAGAGCA
GTGCTCCGCGCCCCCCCGCT

Product: putative aerotaxis receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MRARSSYTNEIETVIPDGAFIYSRTDLKGRIEEANEAFAEISGYTREDMIGKPHNMVRHPDMPAEAFKDMWSDLVAGRPW
RGLVKNRRSDGGYYWVVANASPVREGGRIVGYQSVRSRPTREEVAAAEAAYKRIREGDRSIKVYHGRVVANRPAWINAAV
SLRAQMNAVGVLAVLQALLMVVEGFTAIEVPATLMALVAVPSLLYALYFLLIYAPHVQRDLGATAAWLENILTTGDLRHR
FDLKRRDVIGALARRADKVVSSVQATLQGMTEVSVQVEHAAGQVGSRVHDVRLSAQTQSEAASSAAASIEEVTVSIGEVA
AHAASTREVAEETSRVSDEGARITRDASRNIQSLADRVGVSAEQLETLGKRSDEIGRITGVIREIADQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRKLAERTGQATREIGEMIDTIRSETQQAVDTMRAGATQVGEGVERVGAAEESLNRINAEMAVT
MERVTEISHASGEQQVALQDLARHIEQVASMTEQNVAVVADTEDMVNRLEAVVDRMRKAVGQYAV

Sequences:

>Translated_545_residues
MRARSSYTNEIETVIPDGAFIYSRTDLKGRIEEANEAFAEISGYTREDMIGKPHNMVRHPDMPAEAFKDMWSDLVAGRPW
RGLVKNRRSDGGYYWVVANASPVREGGRIVGYQSVRSRPTREEVAAAEAAYKRIREGDRSIKVYHGRVVANRPAWINAAV
SLRAQMNAVGVLAVLQALLMVVEGFTAIEVPATLMALVAVPSLLYALYFLLIYAPHVQRDLGATAAWLENILTTGDLRHR
FDLKRRDVIGALARRADKVVSSVQATLQGMTEVSVQVEHAAGQVGSRVHDVRLSAQTQSEAASSAAASIEEVTVSIGEVA
AHAASTREVAEETSRVSDEGARITRDASRNIQSLADRVGVSAEQLETLGKRSDEIGRITGVIREIADQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRKLAERTGQATREIGEMIDTIRSETQQAVDTMRAGATQVGEGVERVGAAEESLNRINAEMAVT
MERVTEISHASGEQQVALQDLARHIEQVASMTEQNVAVVADTEDMVNRLEAVVDRMRKAVGQYAV
>Mature_545_residues
MRARSSYTNEIETVIPDGAFIYSRTDLKGRIEEANEAFAEISGYTREDMIGKPHNMVRHPDMPAEAFKDMWSDLVAGRPW
RGLVKNRRSDGGYYWVVANASPVREGGRIVGYQSVRSRPTREEVAAAEAAYKRIREGDRSIKVYHGRVVANRPAWINAAV
SLRAQMNAVGVLAVLQALLMVVEGFTAIEVPATLMALVAVPSLLYALYFLLIYAPHVQRDLGATAAWLENILTTGDLRHR
FDLKRRDVIGALARRADKVVSSVQATLQGMTEVSVQVEHAAGQVGSRVHDVRLSAQTQSEAASSAAASIEEVTVSIGEVA
AHAASTREVAEETSRVSDEGARITRDASRNIQSLADRVGVSAEQLETLGKRSDEIGRITGVIREIADQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRKLAERTGQATREIGEMIDTIRSETQQAVDTMRAGATQVGEGVERVGAAEESLNRINAEMAVT
MERVTEISHASGEQQVALQDLARHIEQVASMTEQNVAVVADTEDMVNRLEAVVDRMRKAVGQYAV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=545, Percent_Identity=31.5596330275229, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1787690, Length=345, Percent_Identity=30.4347826086957, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788194, Length=250, Percent_Identity=35.2, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788195, Length=310, Percent_Identity=30.6451612903226, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI2367378, Length=271, Percent_Identity=32.8413284132841, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 59310; Mature: 59310

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARSSYTNEIETVIPDGAFIYSRTDLKGRIEEANEAFAEISGYTREDMIGKPHNMVRHP
CCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHCCCC
DMPAEAFKDMWSDLVAGRPWRGLVKNRRSDGGYYWVVANASPVREGGRIVGYQSVRSRPT
CCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHCCCC
REEVAAAEAAYKRIREGDRSIKVYHGRVVANRPAWINAAVSLRAQMNAVGVLAVLQALLM
HHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VVEGFTAIEVPATLMALVAVPSLLYALYFLLIYAPHVQRDLGATAAWLENILTTGDLRHR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHH
FDLKRRDVIGALARRADKVVSSVQATLQGMTEVSVQVEHAAGQVGSRVHDVRLSAQTQSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHH
AASSAAASIEEVTVSIGEVAAHAASTREVAEETSRVSDEGARITRDASRNIQSLADRVGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
SAEQLETLGKRSDEIGRITGVIREIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRKL
CHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHH
AERTGQATREIGEMIDTIRSETQQAVDTMRAGATQVGEGVERVGAAEESLNRINAEMAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MERVTEISHASGEQQVALQDLARHIEQVASMTEQNVAVVADTEDMVNRLEAVVDRMRKAV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHH
GQYAV
HCCCC
>Mature Secondary Structure
MRARSSYTNEIETVIPDGAFIYSRTDLKGRIEEANEAFAEISGYTREDMIGKPHNMVRHP
CCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHCCCC
DMPAEAFKDMWSDLVAGRPWRGLVKNRRSDGGYYWVVANASPVREGGRIVGYQSVRSRPT
CCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHCCCC
REEVAAAEAAYKRIREGDRSIKVYHGRVVANRPAWINAAVSLRAQMNAVGVLAVLQALLM
HHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VVEGFTAIEVPATLMALVAVPSLLYALYFLLIYAPHVQRDLGATAAWLENILTTGDLRHR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHH
FDLKRRDVIGALARRADKVVSSVQATLQGMTEVSVQVEHAAGQVGSRVHDVRLSAQTQSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHH
AASSAAASIEEVTVSIGEVAAHAASTREVAEETSRVSDEGARITRDASRNIQSLADRVGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
SAEQLETLGKRSDEIGRITGVIREIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRKL
CHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHH
AERTGQATREIGEMIDTIRSETQQAVDTMRAGATQVGEGVERVGAAEESLNRINAEMAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MERVTEISHASGEQQVALQDLARHIEQVASMTEQNVAVVADTEDMVNRLEAVVDRMRKAV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHH
GQYAV
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]