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The map label for this gene is alr

Identifier: 119900214

GI number: 119900214

Start: 4304301

End: 4305362

Strand: Direct

Name: alr

Synonym: azo3925

Alternate gene names: 119900214

Gene position: 4304301-4305362 (Clockwise)

Preceding gene: 119900213

Following gene: 119900226

Centisome position: 98.36

GC content: 72.22

Gene sequence:

>1062_bases
ATGCGCCCCGCCACCGCCCTGATCGACCTCGACGCCCTCCGCCACAACTACCGTCTCGCCCGCAGCCGCCACGGCGGGCG
CGCCCTCGCGGTGGTCAAGGCCAATGCCTACGGCCACGGCGCGGTGCGGTGCGCACAGGCGCTGGCGGCGGAGGCCGACG
GTTTCGCGGTCGCCTTTCTCGACGAGGCGCTGGAGCTGCGCGCGGCCGGCATCACCCAGACCATCGTGCTGCTGGAAGGC
GTGTTCGACGCCGCCGAGCTGGAGCAGGTGGTCGCGCATGGCCTGTGGCCCGTGGTGCATCACGCGGCCCAGATCGAGAT
GATCGAGCAGGCCGCACTGGCGCGCCCGCTCGACATCTGGCTGAAGGTGAACAGCGGCATGAACCGCGCCGGCTTCGTCG
GCGACGCCGTTGGCAGCGCGTGGCAACGCCTGCGTGCGAGCGGCAAGGTCGGCGAGATCACGCTGATGACGCACTTCGCG
CGCGCCGACGAACCCCAGGTGATCGCCACCGCCGAACAACTGGCCGATTTCGACACCGCCACGCGTGGGCTGCCCGGCCC
ACGCAGCCTCGCCAATTCAGCCGCGGTGCTCGGCTGGCCCGACGCGCACGCCGACTGGGCGCGGCCGGGCATCCTGCTTT
ACGGCGCCGACCCGATGCCCGGCGAGGGCAACGGCCTGCAGCCGGTGATGACGCTGGAAAGCGGGGTGATCGCGGTGCGC
GACCTCGCCGCCGGCGCGCCGCTGGGCTACGGCGCACGCTACGTCGCCGAGCGCCCGCGCCGCATCGGCCTGGTGGCGAT
GGGCTATGCCGACGGCTATCCGCGCAGTGCGCCGGACGGCACCCCGGTGGTGGTCGACGGCCAGCCGAGCATGCTGGTCG
GCCGGGTGTCGATGGACATGCTGACGGTGGATCTCACCGACCTGCCTCAGGCCGGCATCGGCAGCCGGGTGGAGCTGTGG
GGCCGGCAGGTGCCGATCAACCAGGTCGCCGCCGGCGCCGGCACCATTGCCTACGAGCTGCTGTGCAACGTCAAACGGGT
GGTCTTTCGCTACCGCGGGTGA

Upstream 100 bases:

>100_bases
GGCCGCGGCAGCGGCTTCGACCTGTCCCCCGCGGCCTGAACCTCACCGGCAGTCGCCGCCTGGCGCTGCCGCCAACCTGT
CCACCCCTCGCCCTGCACGC

Downstream 100 bases:

>100_bases
AGCGCGCCGCGCGGCGCGCTAGGCGGTGCGCGCCGGCTTCGGCGTGAAACCGCGGCAGGGTTCGCCGGAGGCCGCCTCCA
CCTCGATGCAGGGCTTGCGC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MRPATALIDLDALRHNYRLARSRHGGRALAVVKANAYGHGAVRCAQALAAEADGFAVAFLDEALELRAAGITQTIVLLEG
VFDAAELEQVVAHGLWPVVHHAAQIEMIEQAALARPLDIWLKVNSGMNRAGFVGDAVGSAWQRLRASGKVGEITLMTHFA
RADEPQVIATAEQLADFDTATRGLPGPRSLANSAAVLGWPDAHADWARPGILLYGADPMPGEGNGLQPVMTLESGVIAVR
DLAAGAPLGYGARYVAERPRRIGLVAMGYADGYPRSAPDGTPVVVDGQPSMLVGRVSMDMLTVDLTDLPQAGIGSRVELW
GRQVPINQVAAGAGTIAYELLCNVKRVVFRYRG

Sequences:

>Translated_353_residues
MRPATALIDLDALRHNYRLARSRHGGRALAVVKANAYGHGAVRCAQALAAEADGFAVAFLDEALELRAAGITQTIVLLEG
VFDAAELEQVVAHGLWPVVHHAAQIEMIEQAALARPLDIWLKVNSGMNRAGFVGDAVGSAWQRLRASGKVGEITLMTHFA
RADEPQVIATAEQLADFDTATRGLPGPRSLANSAAVLGWPDAHADWARPGILLYGADPMPGEGNGLQPVMTLESGVIAVR
DLAAGAPLGYGARYVAERPRRIGLVAMGYADGYPRSAPDGTPVVVDGQPSMLVGRVSMDMLTVDLTDLPQAGIGSRVELW
GRQVPINQVAAGAGTIAYELLCNVKRVVFRYRG
>Mature_353_residues
MRPATALIDLDALRHNYRLARSRHGGRALAVVKANAYGHGAVRCAQALAAEADGFAVAFLDEALELRAAGITQTIVLLEG
VFDAAELEQVVAHGLWPVVHHAAQIEMIEQAALARPLDIWLKVNSGMNRAGFVGDAVGSAWQRLRASGKVGEITLMTHFA
RADEPQVIATAEQLADFDTATRGLPGPRSLANSAAVLGWPDAHADWARPGILLYGADPMPGEGNGLQPVMTLESGVIAVR
DLAAGAPLGYGARYVAERPRRIGLVAMGYADGYPRSAPDGTPVVVDGQPSMLVGRVSMDMLTVDLTDLPQAGIGSRVELW
GRQVPINQVAAGAGTIAYELLCNVKRVVFRYRG

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1787439, Length=347, Percent_Identity=53.6023054755043, Blast_Score=334, Evalue=4e-93,
Organism=Escherichia coli, GI1790487, Length=358, Percent_Identity=46.3687150837989, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_AZOSB (A1KCI5)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_935427.1
- ProteinModelPortal:   A1KCI5
- SMR:   A1KCI5
- STRING:   A1KCI5
- GeneID:   4608579
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo3925
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   WGKQVLA
- PhylomeDB:   A1KCI5
- ProtClustDB:   CLSK766668
- BioCyc:   ASP62928:AZO3925-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 37419; Mature: 37419

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 33-33 ACT_SITE 250-250

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPATALIDLDALRHNYRLARSRHGGRALAVVKANAYGHGAVRCAQALAAEADGFAVAFL
CCCCHHEEEHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEHH
DEALELRAAGITQTIVLLEGVFDAAELEQVVAHGLWPVVHHAAQIEMIEQAALARPLDIW
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEE
LKVNSGMNRAGFVGDAVGSAWQRLRASGKVGEITLMTHFARADEPQVIATAEQLADFDTA
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCEEEEHHHHHHHHHH
TRGLPGPRSLANSAAVLGWPDAHADWARPGILLYGADPMPGEGNGLQPVMTLESGVIAVR
HCCCCCCHHHHCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCEEEEE
DLAAGAPLGYGARYVAERPRRIGLVAMGYADGYPRSAPDGTPVVVDGQPSMLVGRVSMDM
HHHCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCEEEEEEEEEE
LTVDLTDLPQAGIGSRVELWGRQVPINQVAAGAGTIAYELLCNVKRVVFRYRG
EEEEHHHCCCCCCCCHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRPATALIDLDALRHNYRLARSRHGGRALAVVKANAYGHGAVRCAQALAAEADGFAVAFL
CCCCHHEEEHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEHH
DEALELRAAGITQTIVLLEGVFDAAELEQVVAHGLWPVVHHAAQIEMIEQAALARPLDIW
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEE
LKVNSGMNRAGFVGDAVGSAWQRLRASGKVGEITLMTHFARADEPQVIATAEQLADFDTA
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCEEEEHHHHHHHHHH
TRGLPGPRSLANSAAVLGWPDAHADWARPGILLYGADPMPGEGNGLQPVMTLESGVIAVR
HCCCCCCHHHHCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCEEEEE
DLAAGAPLGYGARYVAERPRRIGLVAMGYADGYPRSAPDGTPVVVDGQPSMLVGRVSMDM
HHHCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCEEEEEEEEEE
LTVDLTDLPQAGIGSRVELWGRQVPINQVAAGAGTIAYELLCNVKRVVFRYRG
EEEEHHHCCCCCCCCHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA