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The map label for this gene is paaK [H]

Identifier: 119899730

GI number: 119899730

Start: 3773552

End: 3774784

Strand: Reverse

Name: paaK [H]

Synonym: azo3441

Alternate gene names: 119899730

Gene position: 3774784-3773552 (Counterclockwise)

Preceding gene: 119899731

Following gene: 119899729

Centisome position: 86.26

GC content: 69.18

Gene sequence:

>1233_bases
ATGAGCTACTACGACGCCCGAGAAACCCGTGATCCCGCCGCGCGCGAGCAGGATTTGTTCGCCCGCCTGCCGGCACAGAT
CGCCCATGCACGCACGCATGCGCCGGCCTTCGCGCGCCTGCTGGCGGATATCGATCCGGGCGCGGTCACCGGCCGCGAAG
CGCTGGCGCGGCTGCCGGTGATCCGCAAGTCCGAACTGCTGGAGGCGCAGAAGGCCGCCCGGCCCTTCGGCGGATTTGCC
GCGGTGGGCTGGGGCGCGAGTTGCCGCCGGGTGTTCGCGTCGCCGGGTCCGCTGTACGAGCCGGAAGGCAGCCGGGCCGA
CTACTACCGTATGGCGCGCGCCTTTCATGCCGCCGGCTTTCGCGCGGGCGACCTGGTGCACAACACCTTCTCGTATCACT
TCACGCCGGCCGGCTCGATGATGGAAACCGCTGCGCACGCCCTTGGCTGCACGGTCTTTCCGGCCGGCGTCGGGCAGACC
GAGCAACAGGTGGCGGCGATCGCCGACCTGGCCCCCAATGCCTACGCCGGCACGCCGTCCTTTCTGCGCATCCTGCTCGA
CAAGGCGGCGGAGCTTGGGGTGAAGCCTGCCTTCACCAAGGCCTTCGTCTCCGGCGAGGCCTTCCCGCCCAGCCTGCGCG
ACGCGTTTGCCGCGCGCGGCGTGGCCGCCTTCCAGGCCTACGCCACCGCCGATATCGGACTCATCGCCTACGAAACCGAG
GCGCGTGAAGGGATGGTGGTGGACGAGGACATCATCCTCGAGATCGTGCGGCCCGGCACCGGCGATCCGGTGGCCCCCGG
CGAGGTCGGCGAGGTGGTGGTGACCACCTTCAATCCCGACTACCCGCTGATCCGCTTCGGCACCGGGGATCTGTCGGCCT
TGCTGCCCGGTGCTTCGCCCTGCGGGCGCACCAACCTGCGCATCAAGGGCTGGATGGGGCGCGCCGACCAGACTGCCAAG
GTCAAGGGCATGTTCGTCCATCCCGGCCAGATCGCAGACGTGGTCCGGCGTCATCCGCAACTCGGCCGCGCCCGGCTCGT
GGTCGAGAATCCGGATCTGACCGACCGGATGACCTTGCACTGCGAAACCCAGGCGGGCAGCGATGCGCTTGCGGCCGCTG
TCGCTACCAGCATTCGCGAACTGACCAAGTTGCGCGGCGAGGTCGTGTTCTGCGCGCCGGGAACGCTGCCCAACGACGGC
AAGGTCATCGACGACCGGCGCACCTACGAATGA

Upstream 100 bases:

>100_bases
AGTTGAACCGCCCACAACACAGACGACAGCGCGGGGCGGCGTCTTCCCCCGCGCGGTATCCGGCAGGCTGATCCTGTCAC
CCGGTACGGGGAACGCTTCC

Downstream 100 bases:

>100_bases
GCGCCGTGCTTCCCGGGTTCGTTGTGTGTGGGGGATACCGGCCCGGTTCCGGGCCGGTTTTTTTCCGCACCGTATCCCGG
CGCCCAAGCAGGGTCCGCCG

Product: phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSYYDARETRDPAAREQDLFARLPAQIAHARTHAPAFARLLADIDPGAVTGREALARLPVIRKSELLEAQKAARPFGGFA
AVGWGASCRRVFASPGPLYEPEGSRADYYRMARAFHAAGFRAGDLVHNTFSYHFTPAGSMMETAAHALGCTVFPAGVGQT
EQQVAAIADLAPNAYAGTPSFLRILLDKAAELGVKPAFTKAFVSGEAFPPSLRDAFAARGVAAFQAYATADIGLIAYETE
AREGMVVDEDIILEIVRPGTGDPVAPGEVGEVVVTTFNPDYPLIRFGTGDLSALLPGASPCGRTNLRIKGWMGRADQTAK
VKGMFVHPGQIADVVRRHPQLGRARLVVENPDLTDRMTLHCETQAGSDALAAAVATSIRELTKLRGEVVFCAPGTLPNDG
KVIDDRRTYE

Sequences:

>Translated_410_residues
MSYYDARETRDPAAREQDLFARLPAQIAHARTHAPAFARLLADIDPGAVTGREALARLPVIRKSELLEAQKAARPFGGFA
AVGWGASCRRVFASPGPLYEPEGSRADYYRMARAFHAAGFRAGDLVHNTFSYHFTPAGSMMETAAHALGCTVFPAGVGQT
EQQVAAIADLAPNAYAGTPSFLRILLDKAAELGVKPAFTKAFVSGEAFPPSLRDAFAARGVAAFQAYATADIGLIAYETE
AREGMVVDEDIILEIVRPGTGDPVAPGEVGEVVVTTFNPDYPLIRFGTGDLSALLPGASPCGRTNLRIKGWMGRADQTAK
VKGMFVHPGQIADVVRRHPQLGRARLVVENPDLTDRMTLHCETQAGSDALAAAVATSIRELTKLRGEVVFCAPGTLPNDG
KVIDDRRTYE
>Mature_409_residues
SYYDARETRDPAAREQDLFARLPAQIAHARTHAPAFARLLADIDPGAVTGREALARLPVIRKSELLEAQKAARPFGGFAA
VGWGASCRRVFASPGPLYEPEGSRADYYRMARAFHAAGFRAGDLVHNTFSYHFTPAGSMMETAAHALGCTVFPAGVGQTE
QQVAAIADLAPNAYAGTPSFLRILLDKAAELGVKPAFTKAFVSGEAFPPSLRDAFAARGVAAFQAYATADIGLIAYETEA
REGMVVDEDIILEIVRPGTGDPVAPGEVGEVVVTTFNPDYPLIRFGTGDLSALLPGASPCGRTNLRIKGWMGRADQTAKV
KGMFVHPGQIADVVRRHPQLGRARLVVENPDLTDRMTLHCETQAGSDALAAAVATSIRELTKLRGEVVFCAPGTLPNDGK
VIDDRRTYE

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=409, Percent_Identity=26.6503667481663, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 43879; Mature: 43748

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYYDARETRDPAAREQDLFARLPAQIAHARTHAPAFARLLADIDPGAVTGREALARLPV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHCCC
IRKSELLEAQKAARPFGGFAAVGWGASCRRVFASPGPLYEPEGSRADYYRMARAFHAAGF
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
RAGDLVHNTFSYHFTPAGSMMETAAHALGCTVFPAGVGQTEQQVAAIADLAPNAYAGTPS
CCCHHHHCCEEEEECCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCCCCCCCHH
FLRILLDKAAELGVKPAFTKAFVSGEAFPPSLRDAFAARGVAAFQAYATADIGLIAYETE
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEECC
AREGMVVDEDIILEIVRPGTGDPVAPGEVGEVVVTTFNPDYPLIRFGTGDLSALLPGASP
CCCCEEECHHHHHEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCHHHHCCCCCC
CGRTNLRIKGWMGRADQTAKVKGMFVHPGQIADVVRRHPQLGRARLVVENPDLTDRMTLH
CCCCCEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
CETQAGSDALAAAVATSIRELTKLRGEVVFCAPGTLPNDGKVIDDRRTYE
EECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
SYYDARETRDPAAREQDLFARLPAQIAHARTHAPAFARLLADIDPGAVTGREALARLPV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHCCC
IRKSELLEAQKAARPFGGFAAVGWGASCRRVFASPGPLYEPEGSRADYYRMARAFHAAGF
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
RAGDLVHNTFSYHFTPAGSMMETAAHALGCTVFPAGVGQTEQQVAAIADLAPNAYAGTPS
CCCHHHHCCEEEEECCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCCCCCCCHH
FLRILLDKAAELGVKPAFTKAFVSGEAFPPSLRDAFAARGVAAFQAYATADIGLIAYETE
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEECC
AREGMVVDEDIILEIVRPGTGDPVAPGEVGEVVVTTFNPDYPLIRFGTGDLSALLPGASP
CCCCEEECHHHHHEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCHHHHCCCCCC
CGRTNLRIKGWMGRADQTAKVKGMFVHPGQIADVVRRHPQLGRARLVVENPDLTDRMTLH
CCCCCEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
CETQAGSDALAAAVATSIRELTKLRGEVVFCAPGTLPNDGKVIDDRRTYE
EECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]