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The map label for this gene is sucD [H]

Identifier: 119899621

GI number: 119899621

Start: 3672838

End: 3673731

Strand: Reverse

Name: sucD [H]

Synonym: azo3332

Alternate gene names: 119899621

Gene position: 3673731-3672838 (Counterclockwise)

Preceding gene: 119899622

Following gene: 119899620

Centisome position: 83.95

GC content: 63.53

Gene sequence:

>894_bases
ATGTCCATCTACATCAACAAAGACACCAAGGTCATCACCCAGGGCATCACCGGGAAGACCGGCCAGTTCCATACCGAAAA
GTGCCAGGAATACGCCAACGGCAAGAACTGCTTCGTTGCCGGCGTGAACCCCAAGAAGGCGGGCGAGCGGATCTTCGACA
TCCCCATCTACGCCTCGGTCAAGGAAGCCGCTTCTGAAACCGGCGCCACCGTTTCCGTCATCTACGTGCCGCCCGCCGGC
GCTGCCGCCGCCATCTGGGAAGCCGTTGAAGCCGATCTCGACCTCGCGATCTGCATCACCGAAGGCATCCCGGTCCGCGA
CATGCTGGAAGTGCGCAACAAGATGAAGGCCAAGGAAGCCGCGGGTGGCAAGAAGACCCTGCTGCTGGGGCCGAACTGCC
CGGGTCTGATCACCCCGGACGAAATCAAGATCGGCATCATGCCGGGCCACATCCACCGCAAGGGCCGCATCGGCGTCGTG
TCGCGTTCCGGCACCCTGACGTACGAAGCCGTGGCACAGCTCACCGAGCTGGGCCTGGGCCAGTCGTCCGCGGTCGGTAT
CGGCGGCGACCCGATCAACGGTCTGAAGCACATCGACGTCATGAAGGCCTTCAATGACGATCCGGACACCGACGCGGTCA
TCATGATCGGTGAGATCGGCGGCCCGGACGAAGCCGAAGCGGCGCTGTGGTGCAAGGCCAACATGAAGAAGCCGGTGGTC
GGCTTCATCGCCGGCGTGACCGCGCCGGCCGGCAAGCGCATGGGCCACGCCGGTGCGCTGATCTCTGGCGGTGCCGATAC
TGCCGACGCCAAGCTCGCCATCATGGAAGAGTGCGGCTTCAAGGTGACGCGCAACCCGTCGGAAATGGGCAAGCTGCTGA
AGTCGCTGCTGTAA

Upstream 100 bases:

>100_bases
AGAAGATCCTCGCCGAGTCGGGCCTGCCCATCATCTCCGCCGACACCATGGCGGAAGCCGCGACCAAGATCGTGGCTGAG
GTCAAGTAAGGAGAGTTCGA

Downstream 100 bases:

>100_bases
GCGTCTTCATCTGTGCCGTGAAAAAGCGCCGGCTTGTCCGGCGCTTTTTTGTCTACCCGCGAAATCGTGCGCGCTAGAAT
GGTCCGATTCTCCCGCCGCG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSIYINKDTKVITQGITGKTGQFHTEKCQEYANGKNCFVAGVNPKKAGERIFDIPIYASVKEAASETGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVRDMLEVRNKMKAKEAAGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVV
SRSGTLTYEAVAQLTELGLGQSSAVGIGGDPINGLKHIDVMKAFNDDPDTDAVIMIGEIGGPDEAEAALWCKANMKKPVV
GFIAGVTAPAGKRMGHAGALISGGADTADAKLAIMEECGFKVTRNPSEMGKLLKSLL

Sequences:

>Translated_297_residues
MSIYINKDTKVITQGITGKTGQFHTEKCQEYANGKNCFVAGVNPKKAGERIFDIPIYASVKEAASETGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVRDMLEVRNKMKAKEAAGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVV
SRSGTLTYEAVAQLTELGLGQSSAVGIGGDPINGLKHIDVMKAFNDDPDTDAVIMIGEIGGPDEAEAALWCKANMKKPVV
GFIAGVTAPAGKRMGHAGALISGGADTADAKLAIMEECGFKVTRNPSEMGKLLKSLL
>Mature_296_residues
SIYINKDTKVITQGITGKTGQFHTEKCQEYANGKNCFVAGVNPKKAGERIFDIPIYASVKEAASETGATVSVIYVPPAGA
AAAIWEAVEADLDLAICITEGIPVRDMLEVRNKMKAKEAAGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVS
RSGTLTYEAVAQLTELGLGQSSAVGIGGDPINGLKHIDVMKAFNDDPDTDAVIMIGEIGGPDEAEAALWCKANMKKPVVG
FIAGVTAPAGKRMGHAGALISGGADTADAKLAIMEECGFKVTRNPSEMGKLLKSLL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=292, Percent_Identity=53.7671232876712, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI38569423, Length=210, Percent_Identity=30.4761904761905, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI38569421, Length=210, Percent_Identity=30.4761904761905, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI1786949, Length=297, Percent_Identity=54.2087542087542, Blast_Score=311, Evalue=3e-86,
Organism=Escherichia coli, GI1786513, Length=189, Percent_Identity=28.042328042328, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=293, Percent_Identity=53.9249146757679, Blast_Score=288, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI17553126, Length=300, Percent_Identity=51, Blast_Score=277, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI17557344, Length=262, Percent_Identity=26.7175572519084, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=265, Percent_Identity=25.6603773584906, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324716, Length=300, Percent_Identity=48.3333333333333, Blast_Score=260, Evalue=2e-70,
Organism=Drosophila melanogaster, GI21356559, Length=296, Percent_Identity=50, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI28574296, Length=296, Percent_Identity=53.0405405405405, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI281363477, Length=263, Percent_Identity=25.8555133079848, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281363475, Length=263, Percent_Identity=25.8555133079848, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363473, Length=263, Percent_Identity=25.8555133079848, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31055; Mature: 30924

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYINKDTKVITQGITGKTGQFHTEKCQEYANGKNCFVAGVNPKKAGERIFDIPIYASV
CEEEEECCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHCCEEEECCCHHHH
KEAASETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMLEVRNKMKAKEA
HHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
AGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVAQLTELGLG
CCCCEEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHHHHHHHHHHHCCC
QSSAVGIGGDPINGLKHIDVMKAFNDDPDTDAVIMIGEIGGPDEAEAALWCKANMKKPVV
CCCEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHH
GFIAGVTAPAGKRMGHAGALISGGADTADAKLAIMEECGFKVTRNPSEMGKLLKSLL
HHHHCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEHHCCCEEECCHHHHHHHHHHHC
>Mature Secondary Structure 
SIYINKDTKVITQGITGKTGQFHTEKCQEYANGKNCFVAGVNPKKAGERIFDIPIYASV
EEEEECCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHCCEEEECCCHHHH
KEAASETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMLEVRNKMKAKEA
HHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
AGGKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVAQLTELGLG
CCCCEEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHHHHHHHHHHHCCC
QSSAVGIGGDPINGLKHIDVMKAFNDDPDTDAVIMIGEIGGPDEAEAALWCKANMKKPVV
CCCEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHH
GFIAGVTAPAGKRMGHAGALISGGADTADAKLAIMEECGFKVTRNPSEMGKLLKSLL
HHHHCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEHHCCCEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]