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The map label for this gene is sucC [H]

Identifier: 119899622

GI number: 119899622

Start: 3673743

End: 3674903

Strand: Reverse

Name: sucC [H]

Synonym: azo3333

Alternate gene names: 119899622

Gene position: 3674903-3673743 (Counterclockwise)

Preceding gene: 119899623

Following gene: 119899621

Centisome position: 83.98

GC content: 60.81

Gene sequence:

>1161_bases
ATGAAGATTCATGAGTATCAGGCAAAAGAAGTACTGAGAAAGTACGGCGTCGTCACGCCGCGCGGCATTCCGTGTTTTTC
CGTCGATGAGGCGGTGAAGGCGGCTGAAGAACTCGGCGGCAAGATCTGGGTGGTGAAGGCCCAGATCCATGCTGGCGGTC
GCGGCAAGGGCGGTGGCGTCAAGCTCGGCAAGTCGCTGGACGAAGTTCGCACCCTGGCTGGCCAGATCCTGGGCATGCAG
CTGGTCACCCATCAGACCGGCCCGGAAGGCCAGAAGGTTCGCCGCCTCCTGATCGAGGAAGGCGCCGACATCAAGAAGGA
ATACTACGTTGCCGCGCTGACCGACCGCGCTACCCAGAAGGTTGCCATGATGGCCTCCTCCGAAGGTGGCATGGACATCG
AGGAAGTCGCGCACAACACCCCCGAGAAGATCATCAAGGTCTTCGTCGATCCGCTCGCCGGCCTGACCGACGCGCAGGCC
ATCGAACTGGCCAAGGGTATCGGCGTTCCTGAAGCTTCGATCCCGCAAGCGGTCGACACCTTCAAGAAGCTCTACACCTG
CTACATGGAAACCGATGCCTCGCTGGCGGAAATCAACCCGCTGATCCTCGAAGGCAACGGCAACATCAAGGCGCTCGACG
CCAAGTTCAACTTCGACTCCAACGCGCTCTTCCGTCACCCGGAAATCGTTGCCTACCGCGACCTGGATGAAGAAGACGCC
GACGAAATCGAAGCCTCCAAGTTCGACCTCGCCTACATCAGCCTCGACGGCAACATCGGCTGCCTGGTGAACGGCGCCGG
TCTGGCGATGGCCACCATGGACACCATCAAGCTGTTCGGTGCCGAGCCGGCCAACTTCCTCGACGTGGGCGGCGGCGCCA
CCACCGAGAAGGTCACCGAAGCCTTCAAGATCATGCTCAAGAACCCCAAAGTCAAGGGCATCCTGGTCAACATCTTCGGC
GGCATCATGAAGTGCGACACCATCGCCACCGGCGTGGTCGCTGCAGCCAAGGAAGTGAATCTCTCCGTCCCGCTCGTGGT
GCGCATGAAGGGCACCAACGAAGACCTCGGCAAGAAGATCCTCGCCGAGTCGGGCCTGCCCATCATCTCCGCCGACACCA
TGGCGGAAGCCGCGACCAAGATCGTGGCTGAGGTCAAGTAA

Upstream 100 bases:

>100_bases
GACGAGGGAGACGGCGCCCGTCGCGGAGCGAAGCTCCGAAGCGTCCCATCAACCTGCTCGCGGCGGCAAGGCACGTCGTG
ACTTCGATCGAAGGGCAACC

Downstream 100 bases:

>100_bases
GGAGAGTTCGAATGTCCATCTACATCAACAAAGACACCAAGGTCATCACCCAGGGCATCACCGGGAAGACCGGCCAGTTC
CATACCGAAAAGTGCCAGGA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKIHEYQAKEVLRKYGVVTPRGIPCFSVDEAVKAAEELGGKIWVVKAQIHAGGRGKGGGVKLGKSLDEVRTLAGQILGMQ
LVTHQTGPEGQKVRRLLIEEGADIKKEYYVAALTDRATQKVAMMASSEGGMDIEEVAHNTPEKIIKVFVDPLAGLTDAQA
IELAKGIGVPEASIPQAVDTFKKLYTCYMETDASLAEINPLILEGNGNIKALDAKFNFDSNALFRHPEIVAYRDLDEEDA
DEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGAEPANFLDVGGGATTEKVTEAFKIMLKNPKVKGILVNIFG
GIMKCDTIATGVVAAAKEVNLSVPLVVRMKGTNEDLGKKILAESGLPIISADTMAEAATKIVAEVK

Sequences:

>Translated_386_residues
MKIHEYQAKEVLRKYGVVTPRGIPCFSVDEAVKAAEELGGKIWVVKAQIHAGGRGKGGGVKLGKSLDEVRTLAGQILGMQ
LVTHQTGPEGQKVRRLLIEEGADIKKEYYVAALTDRATQKVAMMASSEGGMDIEEVAHNTPEKIIKVFVDPLAGLTDAQA
IELAKGIGVPEASIPQAVDTFKKLYTCYMETDASLAEINPLILEGNGNIKALDAKFNFDSNALFRHPEIVAYRDLDEEDA
DEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGAEPANFLDVGGGATTEKVTEAFKIMLKNPKVKGILVNIFG
GIMKCDTIATGVVAAAKEVNLSVPLVVRMKGTNEDLGKKILAESGLPIISADTMAEAATKIVAEVK
>Mature_386_residues
MKIHEYQAKEVLRKYGVVTPRGIPCFSVDEAVKAAEELGGKIWVVKAQIHAGGRGKGGGVKLGKSLDEVRTLAGQILGMQ
LVTHQTGPEGQKVRRLLIEEGADIKKEYYVAALTDRATQKVAMMASSEGGMDIEEVAHNTPEKIIKVFVDPLAGLTDAQA
IELAKGIGVPEASIPQAVDTFKKLYTCYMETDASLAEINPLILEGNGNIKALDAKFNFDSNALFRHPEIVAYRDLDEEDA
DEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGAEPANFLDVGGGATTEKVTEAFKIMLKNPKVKGILVNIFG
GIMKCDTIATGVVAAAKEVNLSVPLVVRMKGTNEDLGKKILAESGLPIISADTMAEAATKIVAEVK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=46.2724935732648, Blast_Score=351, Evalue=6e-97,
Organism=Homo sapiens, GI157779135, Length=378, Percent_Identity=46.8253968253968, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=46.2395543175487, Blast_Score=308, Evalue=6e-84,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=51.0362694300518, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=45.4314720812183, Blast_Score=343, Evalue=6e-95,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.6153846153846, Blast_Score=323, Evalue=9e-89,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=45.4081632653061, Blast_Score=342, Evalue=5e-95,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=46.4646464646465, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI161078106, Length=389, Percent_Identity=43.4447300771208, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI24645208, Length=389, Percent_Identity=43.4447300771208, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI281361397, Length=390, Percent_Identity=43.5897435897436, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281361395, Length=390, Percent_Identity=43.5897435897436, Blast_Score=307, Evalue=1e-83,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41191; Mature: 41191

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQAKEVLRKYGVVTPRGIPCFSVDEAVKAAEELGGKIWVVKAQIHAGGRGKGGGV
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KLGKSLDEVRTLAGQILGMQLVTHQTGPEGQKVRRLLIEEGADIKKEYYVAALTDRATQK
ECCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCHHEEEEEEHHHHHHH
VAMMASSEGGMDIEEVAHNTPEKIIKVFVDPLAGLTDAQAIELAKGIGVPEASIPQAVDT
HHEEECCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHH
FKKLYTCYMETDASLAEINPLILEGNGNIKALDAKFNFDSNALFRHPEIVAYRDLDEEDA
HHHHHHHHHCCCCCHHHCCEEEEECCCCEEEEEEEECCCCCCEECCCCEEEECCCCCCCH
DEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGAEPANFLDVGGGATTEKVTE
HHHCCCCEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKIMLKNPKVKGILVNIFGGIMKCDTIATGVVAAAKEVNLSVPLVVRMKGTNEDLGKKI
HHHHHHCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
LAESGLPIISADTMAEAATKIVAEVK
HHHCCCCEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQAKEVLRKYGVVTPRGIPCFSVDEAVKAAEELGGKIWVVKAQIHAGGRGKGGGV
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KLGKSLDEVRTLAGQILGMQLVTHQTGPEGQKVRRLLIEEGADIKKEYYVAALTDRATQK
ECCCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCHHEEEEEEHHHHHHH
VAMMASSEGGMDIEEVAHNTPEKIIKVFVDPLAGLTDAQAIELAKGIGVPEASIPQAVDT
HHEEECCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHH
FKKLYTCYMETDASLAEINPLILEGNGNIKALDAKFNFDSNALFRHPEIVAYRDLDEEDA
HHHHHHHHHCCCCCHHHCCEEEEECCCCEEEEEEEECCCCCCEECCCCEEEECCCCCCCH
DEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGAEPANFLDVGGGATTEKVTE
HHHCCCCEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKIMLKNPKVKGILVNIFGGIMKCDTIATGVVAAAKEVNLSVPLVVRMKGTNEDLGKKI
HHHHHHCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
LAESGLPIISADTMAEAATKIVAEVK
HHHCCCCEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA