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The map label for this gene is trpD

Identifier: 119899612

GI number: 119899612

Start: 3662666

End: 3663703

Strand: Reverse

Name: trpD

Synonym: azo3323

Alternate gene names: 119899612

Gene position: 3663703-3662666 (Counterclockwise)

Preceding gene: 119899613

Following gene: 119899611

Centisome position: 83.72

GC content: 67.05

Gene sequence:

>1038_bases
ATGACGATTACCGCCCAGCAAGCGCTCCAGCGCACCATCGAACACCGCGAAATCTTCTTCGACGAAATGCTGTCGCTGAT
GCGCCAGATCATGGCCGGCGAAGTCTCGCCGGTGATGACCGCCGCCATCCTCACCGGCCTGCGCGTCAAGAAGGAAACCA
TCGGCGAGATCACCGCCGCCGCCACCGTGATGCGCGAGCTCGCCACCAAGGTGGTGGTGCCGCCGCCGCACGACCACTTC
ATCGACGTCGTCGGCACCGGCGGCGACGGCTCGCACACTTTCAACATCTCCACCGCCACCATCTTCGTCACCGCGGCAGC
GGGGGCGCGCGTTGCCAAGCATGGCAACCGCAGCGTGTCGTCCAAGTCCGGCAGTGCGGACGCGCTCGAAGCGCTCGGCG
CCAACATCATGCTGACGCCCGAGCAGGTGGCCGAATGCGTGCAGGCCACCGGCATCGGCTTCATGTTCGCACCCAGCCAC
CACAGCGCGATGAAGAACGTCGCCCCGGTGCGGCGCGAGATGGGCGTGCGCACCATCTTCAACATCCTCGGCCCGCTCAC
CAACCCGGCCGGCGCGCCCAATACCCTGCTCGGCGTGTTCCACCCGGACCTCGTCGGCATCCTGGTGCGCGTAATGGAAC
GCCTTGGCGCCAACCACGTGCTGGTGGTGCACGGCCTGGACGGCATGGACGAAGTCAGCCTCGGCGCCGCCACGATGGTG
GGCGAACTGAAGGACGGCGAGGTCAGCGAATACGAGATCCACCCGGAAGACTACGGCCTGGCGATGGTCGGCAGCCGCAA
CCTGCGTGTCGAGGATGCCGACGAATCGCGCCGGGTGCTGGTGGGTGCGCTGGAAAACCAGCCCGGGCCGGCGCGCGAGA
TCGTCATCTTCAACGCAGGGGTTGCGCTGTATGCGGCCAACCTGGTCGATTCCATCGAGGCCGGCATCGTCCGCGCGCGC
GAACTCGTCGCGAGCGGCGCGGCACGGGCCAAGCTGGACGAGTACGTGCAATTCACGCGCAAGTTCGGAGGCGCCTGA

Upstream 100 bases:

>100_bases
CCCCGAATCGATCATGACCGAGCGCGGCCATGACCTGCTGAAGAACTTCCTCGACTCGACCCGCAGCCTGCCTGCCGCCG
CCTGACCGGAACACGCGACC

Downstream 100 bases:

>100_bases
TGAGCGACATCCTGCAGAAGATCTGCGCGGTCAAGCGCGAGGAAGTCACCGCCGCGCTTGCGGCCAAACCGCTCGCCATC
GTGCGGGCAGAGGCCGAGGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTITAQQALQRTIEHREIFFDEMLSLMRQIMAGEVSPVMTAAILTGLRVKKETIGEITAAATVMRELATKVVVPPPHDHF
IDVVGTGGDGSHTFNISTATIFVTAAAGARVAKHGNRSVSSKSGSADALEALGANIMLTPEQVAECVQATGIGFMFAPSH
HSAMKNVAPVRREMGVRTIFNILGPLTNPAGAPNTLLGVFHPDLVGILVRVMERLGANHVLVVHGLDGMDEVSLGAATMV
GELKDGEVSEYEIHPEDYGLAMVGSRNLRVEDADESRRVLVGALENQPGPAREIVIFNAGVALYAANLVDSIEAGIVRAR
ELVASGAARAKLDEYVQFTRKFGGA

Sequences:

>Translated_345_residues
MTITAQQALQRTIEHREIFFDEMLSLMRQIMAGEVSPVMTAAILTGLRVKKETIGEITAAATVMRELATKVVVPPPHDHF
IDVVGTGGDGSHTFNISTATIFVTAAAGARVAKHGNRSVSSKSGSADALEALGANIMLTPEQVAECVQATGIGFMFAPSH
HSAMKNVAPVRREMGVRTIFNILGPLTNPAGAPNTLLGVFHPDLVGILVRVMERLGANHVLVVHGLDGMDEVSLGAATMV
GELKDGEVSEYEIHPEDYGLAMVGSRNLRVEDADESRRVLVGALENQPGPAREIVIFNAGVALYAANLVDSIEAGIVRAR
ELVASGAARAKLDEYVQFTRKFGGA
>Mature_344_residues
TITAQQALQRTIEHREIFFDEMLSLMRQIMAGEVSPVMTAAILTGLRVKKETIGEITAAATVMRELATKVVVPPPHDHFI
DVVGTGGDGSHTFNISTATIFVTAAAGARVAKHGNRSVSSKSGSADALEALGANIMLTPEQVAECVQATGIGFMFAPSHH
SAMKNVAPVRREMGVRTIFNILGPLTNPAGAPNTLLGVFHPDLVGILVRVMERLGANHVLVVHGLDGMDEVSLGAATMVG
ELKDGEVSEYEIHPEDYGLAMVGSRNLRVEDADESRRVLVGALENQPGPAREIVIFNAGVALYAANLVDSIEAGIVRARE
LVASGAARAKLDEYVQFTRKFGGA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=284, Percent_Identity=41.5492957746479, Blast_Score=202, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=340, Percent_Identity=27.6470588235294, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_AZOSB (A1KAT3)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_934825.1
- ProteinModelPortal:   A1KAT3
- SMR:   A1KAT3
- STRING:   A1KAT3
- GeneID:   4610031
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo3323
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   A1KAT3
- ProtClustDB:   PRK00188
- BioCyc:   ASP62928:AZO3323-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36626; Mature: 36494

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITAQQALQRTIEHREIFFDEMLSLMRQIMAGEVSPVMTAAILTGLRVKKETIGEITAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATVMRELATKVVVPPPHDHFIDVVGTGGDGSHTFNISTATIFVTAAAGARVAKHGNRSVS
HHHHHHHHHCEECCCCCCCEEEEEECCCCCCEEEEEEEEEEEEEECCCCHHHHCCCCCCC
SKSGSADALEALGANIMLTPEQVAECVQATGIGFMFAPSHHSAMKNVAPVRREMGVRTIF
CCCCCHHHHHHCCCCEEECHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
NILGPLTNPAGAPNTLLGVFHPDLVGILVRVMERLGANHVLVVHGLDGMDEVSLGAATMV
HHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCHHHHH
GELKDGEVSEYEIHPEDYGLAMVGSRNLRVEDADESRRVLVGALENQPGPAREIVIFNAG
CCCCCCCCCEEEECCCCCCEEEECCCCCEEECCCCCCEEEEEECCCCCCCCEEEEEEECC
VALYAANLVDSIEAGIVRARELVASGAARAKLDEYVQFTRKFGGA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TITAQQALQRTIEHREIFFDEMLSLMRQIMAGEVSPVMTAAILTGLRVKKETIGEITAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATVMRELATKVVVPPPHDHFIDVVGTGGDGSHTFNISTATIFVTAAAGARVAKHGNRSVS
HHHHHHHHHCEECCCCCCCEEEEEECCCCCCEEEEEEEEEEEEEECCCCHHHHCCCCCCC
SKSGSADALEALGANIMLTPEQVAECVQATGIGFMFAPSHHSAMKNVAPVRREMGVRTIF
CCCCCHHHHHHCCCCEEECHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
NILGPLTNPAGAPNTLLGVFHPDLVGILVRVMERLGANHVLVVHGLDGMDEVSLGAATMV
HHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCHHHHH
GELKDGEVSEYEIHPEDYGLAMVGSRNLRVEDADESRRVLVGALENQPGPAREIVIFNAG
CCCCCCCCCEEEECCCCCCEEEECCCCCEEECCCCCCEEEEEECCCCCCCCEEEEEEECC
VALYAANLVDSIEAGIVRARELVASGAARAKLDEYVQFTRKFGGA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA