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The map label for this gene is trpG [H]

Identifier: 119899613

GI number: 119899613

Start: 3663719

End: 3664306

Strand: Reverse

Name: trpG [H]

Synonym: azo3324

Alternate gene names: 119899613

Gene position: 3664306-3663719 (Counterclockwise)

Preceding gene: 119899614

Following gene: 119899612

Centisome position: 83.74

GC content: 64.12

Gene sequence:

>588_bases
ATGTTGCTGATGATCGACAACTACGACAGCTTCACCTACAACCTGGTGCAGTACTTCGGCGAACTCGGCGCCGAGGTGAA
GGTGTTCCGCAACGATGAAATCACCCTCGAGCAGATCGCCCACATGAAGCCCGACCACCTCGTCATCTCGCCCGGGCCGT
GCTCGCCGGCGGAGGCGGGTATCTCGGTGGCGGCAATCCGCGAATTTGCCGGCAAACTCCCCATCCTCGGCGTCTGCCTC
GGCCACCAGAGCATCGGCGCCGCCTTCGGCGGCCGCATCGTCCATGCGCAGAAACTCATGCATGGCAAGACCTCGCCGGT
GCATCACAAGGACCTCGGCGTGTTCCGCGGGCTGCCCAATCCGCTCACCTGCACCCGCTACCATTCGCTCGCGATCGAAC
GCGCCAGCCTGCCCGACTGTCTTGAAGTAACCGCCTGGACGGACGACGGCGAGATCATGGGCGTGCGCCACAAGACGCTG
GACGTCGAAGGCGTGCAGTTCCACCCCGAATCGATCATGACCGAGCGCGGCCATGACCTGCTGAAGAACTTCCTCGACTC
GACCCGCAGCCTGCCTGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CAGCGCCCAAACGGTTCAGCCACTAGCCGCCCAGCGCCCACAGAAATTCCATAGCGTCGCAACCCACACCGGTCGCGACG
CAGCGAAAAGGAAAACCGAC

Downstream 100 bases:

>100_bases
CCGGAACACGCGACCATGACGATTACCGCCCAGCAAGCGCTCCAGCGCACCATCGAACACCGCGAAATCTTCTTCGACGA
AATGCTGTCGCTGATGCGCC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MLLMIDNYDSFTYNLVQYFGELGAEVKVFRNDEITLEQIAHMKPDHLVISPGPCSPAEAGISVAAIREFAGKLPILGVCL
GHQSIGAAFGGRIVHAQKLMHGKTSPVHHKDLGVFRGLPNPLTCTRYHSLAIERASLPDCLEVTAWTDDGEIMGVRHKTL
DVEGVQFHPESIMTERGHDLLKNFLDSTRSLPAAA

Sequences:

>Translated_195_residues
MLLMIDNYDSFTYNLVQYFGELGAEVKVFRNDEITLEQIAHMKPDHLVISPGPCSPAEAGISVAAIREFAGKLPILGVCL
GHQSIGAAFGGRIVHAQKLMHGKTSPVHHKDLGVFRGLPNPLTCTRYHSLAIERASLPDCLEVTAWTDDGEIMGVRHKTL
DVEGVQFHPESIMTERGHDLLKNFLDSTRSLPAAA
>Mature_195_residues
MLLMIDNYDSFTYNLVQYFGELGAEVKVFRNDEITLEQIAHMKPDHLVISPGPCSPAEAGISVAAIREFAGKLPILGVCL
GHQSIGAAFGGRIVHAQKLMHGKTSPVHHKDLGVFRGLPNPLTCTRYHSLAIERASLPDCLEVTAWTDDGEIMGVRHKTL
DVEGVQFHPESIMTERGHDLLKNFLDSTRSLPAAA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=65.945945945946, Blast_Score=266, Evalue=6e-73,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=42.7807486631016, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786215, Length=141, Percent_Identity=29.7872340425532, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=24.7368421052632, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=186, Percent_Identity=52.6881720430108, Blast_Score=218, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6324361, Length=208, Percent_Identity=33.1730769230769, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21368; Mature: 21368

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNLVQYFGELGAEVKVFRNDEITLEQIAHMKPDHLVISPGPCSPAEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCEEEECCCCCCHHHHC
ISVAAIREFAGKLPILGVCLGHQSIGAAFGGRIVHAQKLMHGKTSPVHHKDLGVFRGLPN
CHHHHHHHHHCCCCEEEEEECCHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCC
PLTCTRYHSLAIERASLPDCLEVTAWTDDGEIMGVRHKTLDVEGVQFHPESIMTERGHDL
CCCHHHHHHHEEECCCCCCCEEEEEECCCCCEEEEEEEEECCCCEEECHHHHHHHCCHHH
LKNFLDSTRSLPAAA
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MLLMIDNYDSFTYNLVQYFGELGAEVKVFRNDEITLEQIAHMKPDHLVISPGPCSPAEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCEEEECCCCCCHHHHC
ISVAAIREFAGKLPILGVCLGHQSIGAAFGGRIVHAQKLMHGKTSPVHHKDLGVFRGLPN
CHHHHHHHHHCCCCEEEEEECCHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCC
PLTCTRYHSLAIERASLPDCLEVTAWTDDGEIMGVRHKTLDVEGVQFHPESIMTERGHDL
CCCHHHHHHHEEECCCCCCCEEEEEECCCCCEEEEEEEEECCCCEEECHHHHHHHCCHHH
LKNFLDSTRSLPAAA
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]