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The map label for this gene is recQ [H]

Identifier: 119899607

GI number: 119899607

Start: 3654928

End: 3656775

Strand: Direct

Name: recQ [H]

Synonym: azo3318

Alternate gene names: 119899607

Gene position: 3654928-3656775 (Clockwise)

Preceding gene: 119899605

Following gene: 119899624

Centisome position: 83.52

GC content: 69.7

Gene sequence:

>1848_bases
TTGCCGCTAAAATGCCGGCCGATGTCCGCCTATACCCACACCTCCCCGCACCACGTCCTCGAACACGTCTTCGGCTACAC
CGCGTTCCGCGGCGAGCAACAGGCGATCGTCGAGCATGTCGCGGCCGGCGGGGACGCGCTGGTGCTGATGCCCACCGGCG
GCGGCAAGTCGCTGTGCTACCAGGTGCCGGCGCTGCTGCGCGAGGGCACCGCGATCGTGGTGTCGCCGCTGATCGCGCTG
ATGCACGACCAGGTGAGCGCGCTGGTGGAAGCGGGCGTGAAAGCGGCCTTCCTCAACTCCAGCCTGGACGCGGAAGAAGC
GCGCAGGGTGGAGCGCGCGCTCTATGCCGGCGAACTCGACCTGCTCTACGTGGCGCCCGAACGGCTGATGACGCCGCGCT
TCCTCGACCAGCTCGACCACCTGCGCGACACCCACCGCCTGGCGCTGTTCGCGATCGACGAGGCGCACTGCGTGTCGCAG
TGGGGCCACGATTTCCGGCCGGAATACCTGCAGCTGTCGATCCTGCCGGAGCGCTACCCGGCGATCCCGCGCATCGCGCT
GACCGCCACCGCCGACCGCCAGACCCGCGAGGAGATCGCCACCCGGCTGCGGCTGGAAGATGCGCGCCGCTTCATCTCCA
GCTTCGACCGCCCCAACATCCGCTACACCATCGTCGACAAGGACGATCCGCGCCGCCAGCTGCTGCACTTCATCCGCGAG
GAGTTTCCGTCCGAGGCCGGCGTGGTGTATTGCCTGTCGCGGCGCAAGGTGGAGGAAACCGCCGCCTGGCTGCAGGAACA
GGGCATCAACGCGCTGCCCTACCACGCCGGGCTCGGCCAGGACGTGCGCGCCGAACACCAGACCCGCTTCCTGCGCGAGG
ACGGCATCGTGATGGTGGCGACCATCGCCTTCGGCATGGGCATCGACAAGCCCGACGTGCGCTTCGTCGCCCACCTCGAC
CTGCCGCGCTCGATCGAGGGCTACTACCAGGAAACTGGCCGCGCCGGCCGCGACGGCCTGCCGGCGCAGGCGTGGATGGC
GTGGGGCGCGCAGGACGTGGTGCAGCAGCGCCGCATGATCGACGAGTCCGAAGCGAGCGAGGACTTCAAGCGCCTCGCGC
GCAACCGGCTGGACGTGCTCGTCGGCCTGGTCGAAGCCACCACCTGCCGCCGCCAGCATCTGCTCGCCTACTTCGGCGAG
GAGTCCGGCCCTTGCGGCAACTGCGACAACTGCCTCAGCCCGCCGCAGACCTGGGACGCCACCGAGGCCGCGCGCAAGGC
CTTGAGCTGCGTCTATCGCACCGGCCAGCGCTACGGCACCGGCCATCTGATCGACGTGCTGCGCGGCGAACGCACCGAGA
AAGTGCTGGAACGCCAGCACGAGGGGCTCAGCACCTTCGGCATCGGCAGCGAACTCGACGAAAAGCGCTGGCGCACCGTG
TTCCGCCAGCTGATCGCACGCGAATACCTCGCAGTGGATCACGAGCGCTACAACGCGCTCGCGCTCACCGAACTCGCCCG
CCCGCTGCTGCGCGGCGAGGCCGAATTCCACCTGCGCCTGGAGCGCGAACGCAGCAAGGGCCGCGGCAAGTCGCGCTCGG
CCGCCCGCATGGACATCCCCGGCGGCGTGCCGACCACGCTGTTCGACCGCCTGCGCGCGTGGCGCGCCGCCACCGCCAAG
GAACGCAACGTGCCGGCCTACGTCATCTTCCACGACGCCACGCTGCGCGAAATCGCCATCGCCCGCCCGACCAGCATGGC
CGAACTCGGCGGCATCAGCGGCATCGGCGACCGCAAGCTGGAGGCTTACGGCCAGGCCATCGTCGATCTGGTGGCCGAGG
TCGGCTGA

Upstream 100 bases:

>100_bases
CCTCCGTCCATGCGAAAAATATTAGACCGATCGTCTATGAAATAACAAGGAGAATCTGCGCCGGCCCGCGCTGATGCTCC
GGCGGCCGGGCGGGTAGCGA

Downstream 100 bases:

>100_bases
GGCAGCCGACCCCCAAAGAAAAACGGGGCGGGCCCGGATGGGCGCGCTCCGCTTTGCACGACCTGCGCGGCAGGCTTACA
GCACTTTCAGCAGTTCGACT

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MPLKCRPMSAYTHTSPHHVLEHVFGYTAFRGEQQAIVEHVAAGGDALVLMPTGGGKSLCYQVPALLREGTAIVVSPLIAL
MHDQVSALVEAGVKAAFLNSSLDAEEARRVERALYAGELDLLYVAPERLMTPRFLDQLDHLRDTHRLALFAIDEAHCVSQ
WGHDFRPEYLQLSILPERYPAIPRIALTATADRQTREEIATRLRLEDARRFISSFDRPNIRYTIVDKDDPRRQLLHFIRE
EFPSEAGVVYCLSRRKVEETAAWLQEQGINALPYHAGLGQDVRAEHQTRFLREDGIVMVATIAFGMGIDKPDVRFVAHLD
LPRSIEGYYQETGRAGRDGLPAQAWMAWGAQDVVQQRRMIDESEASEDFKRLARNRLDVLVGLVEATTCRRQHLLAYFGE
ESGPCGNCDNCLSPPQTWDATEAARKALSCVYRTGQRYGTGHLIDVLRGERTEKVLERQHEGLSTFGIGSELDEKRWRTV
FRQLIAREYLAVDHERYNALALTELARPLLRGEAEFHLRLERERSKGRGKSRSAARMDIPGGVPTTLFDRLRAWRAATAK
ERNVPAYVIFHDATLREIAIARPTSMAELGGISGIGDRKLEAYGQAIVDLVAEVG

Sequences:

>Translated_615_residues
MPLKCRPMSAYTHTSPHHVLEHVFGYTAFRGEQQAIVEHVAAGGDALVLMPTGGGKSLCYQVPALLREGTAIVVSPLIAL
MHDQVSALVEAGVKAAFLNSSLDAEEARRVERALYAGELDLLYVAPERLMTPRFLDQLDHLRDTHRLALFAIDEAHCVSQ
WGHDFRPEYLQLSILPERYPAIPRIALTATADRQTREEIATRLRLEDARRFISSFDRPNIRYTIVDKDDPRRQLLHFIRE
EFPSEAGVVYCLSRRKVEETAAWLQEQGINALPYHAGLGQDVRAEHQTRFLREDGIVMVATIAFGMGIDKPDVRFVAHLD
LPRSIEGYYQETGRAGRDGLPAQAWMAWGAQDVVQQRRMIDESEASEDFKRLARNRLDVLVGLVEATTCRRQHLLAYFGE
ESGPCGNCDNCLSPPQTWDATEAARKALSCVYRTGQRYGTGHLIDVLRGERTEKVLERQHEGLSTFGIGSELDEKRWRTV
FRQLIAREYLAVDHERYNALALTELARPLLRGEAEFHLRLERERSKGRGKSRSAARMDIPGGVPTTLFDRLRAWRAATAK
ERNVPAYVIFHDATLREIAIARPTSMAELGGISGIGDRKLEAYGQAIVDLVAEVG
>Mature_614_residues
PLKCRPMSAYTHTSPHHVLEHVFGYTAFRGEQQAIVEHVAAGGDALVLMPTGGGKSLCYQVPALLREGTAIVVSPLIALM
HDQVSALVEAGVKAAFLNSSLDAEEARRVERALYAGELDLLYVAPERLMTPRFLDQLDHLRDTHRLALFAIDEAHCVSQW
GHDFRPEYLQLSILPERYPAIPRIALTATADRQTREEIATRLRLEDARRFISSFDRPNIRYTIVDKDDPRRQLLHFIREE
FPSEAGVVYCLSRRKVEETAAWLQEQGINALPYHAGLGQDVRAEHQTRFLREDGIVMVATIAFGMGIDKPDVRFVAHLDL
PRSIEGYYQETGRAGRDGLPAQAWMAWGAQDVVQQRRMIDESEASEDFKRLARNRLDVLVGLVEATTCRRQHLLAYFGEE
SGPCGNCDNCLSPPQTWDATEAARKALSCVYRTGQRYGTGHLIDVLRGERTEKVLERQHEGLSTFGIGSELDEKRWRTVF
RQLIAREYLAVDHERYNALALTELARPLLRGEAEFHLRLERERSKGRGKSRSAARMDIPGGVPTTLFDRLRAWRAATAKE
RNVPAYVIFHDATLREIAIARPTSMAELGGISGIGDRKLEAYGQAIVDLVAEVG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=643, Percent_Identity=34.0590979782271, Blast_Score=351, Evalue=1e-96,
Organism=Homo sapiens, GI14591902, Length=404, Percent_Identity=37.1287128712871, Blast_Score=283, Evalue=4e-76,
Organism=Homo sapiens, GI14591904, Length=404, Percent_Identity=37.1287128712871, Blast_Score=283, Evalue=4e-76,
Organism=Homo sapiens, GI148612816, Length=460, Percent_Identity=38.2608695652174, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI169218196, Length=523, Percent_Identity=33.6520076481836, Blast_Score=268, Evalue=9e-72,
Organism=Homo sapiens, GI110735439, Length=523, Percent_Identity=33.6520076481836, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI51242943, Length=386, Percent_Identity=40.6735751295337, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI51242947, Length=368, Percent_Identity=41.5760869565217, Blast_Score=263, Evalue=4e-70,
Organism=Homo sapiens, GI284005309, Length=392, Percent_Identity=36.2244897959184, Blast_Score=191, Evalue=1e-48,
Organism=Escherichia coli, GI48994977, Length=596, Percent_Identity=46.9798657718121, Blast_Score=546, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI25145561, Length=652, Percent_Identity=34.5092024539877, Blast_Score=339, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI71987997, Length=469, Percent_Identity=36.2473347547974, Blast_Score=301, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI71987993, Length=469, Percent_Identity=36.2473347547974, Blast_Score=301, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI32564293, Length=683, Percent_Identity=30.7467057101025, Blast_Score=288, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17552866, Length=443, Percent_Identity=35.4401805869075, Blast_Score=252, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI17555296, Length=368, Percent_Identity=24.4565217391304, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=541, Percent_Identity=35.8595194085028, Blast_Score=340, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6321360, Length=340, Percent_Identity=23.2352941176471, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24646066, Length=638, Percent_Identity=35.1097178683386, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24664226, Length=435, Percent_Identity=39.7701149425287, Blast_Score=287, Evalue=2e-77,
Organism=Drosophila melanogaster, GI62472181, Length=438, Percent_Identity=39.4977168949772, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24664230, Length=438, Percent_Identity=39.4977168949772, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI21358123, Length=376, Percent_Identity=37.5, Blast_Score=212, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 69180; Mature: 69048

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKCRPMSAYTHTSPHHVLEHVFGYTAFRGEQQAIVEHVAAGGDALVLMPTGGGKSLCY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCHHHH
QVPALLREGTAIVVSPLIALMHDQVSALVEAGVKAAFLNSSLDAEEARRVERALYAGELD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCE
LLYVAPERLMTPRFLDQLDHLRDTHRLALFAIDEAHCVSQWGHDFRPEYLQLSILPERYP
EEEECHHHHCCHHHHHHHHHHHHHHEEEEEEECHHHHHHHCCCCCCCCEEEEEECHHHCC
AIPRIALTATADRQTREEIATRLRLEDARRFISSFDRPNIRYTIVDKDDPRRQLLHFIRE
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
EFPSEAGVVYCLSRRKVEETAAWLQEQGINALPYHAGLGQDVRAEHQTRFLREDGIVMVA
HCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEE
TIAFGMGIDKPDVRFVAHLDLPRSIEGYYQETGRAGRDGLPAQAWMAWGAQDVVQQRRMI
EHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHC
DESEASEDFKRLARNRLDVLVGLVEATTCRRQHLLAYFGEESGPCGNCDNCLSPPQTWDA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
TEAARKALSCVYRTGQRYGTGHLIDVLRGERTEKVLERQHEGLSTFGIGSELDEKRWRTV
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
FRQLIAREYLAVDHERYNALALTELARPLLRGEAEFHLRLERERSKGRGKSRSAARMDIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCEECCC
GGVPTTLFDRLRAWRAATAKERNVPAYVIFHDATLREIAIARPTSMAELGGISGIGDRKL
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCCCCHHHHCCCCCCCCHHH
EAYGQAIVDLVAEVG
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLKCRPMSAYTHTSPHHVLEHVFGYTAFRGEQQAIVEHVAAGGDALVLMPTGGGKSLCY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCHHHH
QVPALLREGTAIVVSPLIALMHDQVSALVEAGVKAAFLNSSLDAEEARRVERALYAGELD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCE
LLYVAPERLMTPRFLDQLDHLRDTHRLALFAIDEAHCVSQWGHDFRPEYLQLSILPERYP
EEEECHHHHCCHHHHHHHHHHHHHHEEEEEEECHHHHHHHCCCCCCCCEEEEEECHHHCC
AIPRIALTATADRQTREEIATRLRLEDARRFISSFDRPNIRYTIVDKDDPRRQLLHFIRE
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
EFPSEAGVVYCLSRRKVEETAAWLQEQGINALPYHAGLGQDVRAEHQTRFLREDGIVMVA
HCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEE
TIAFGMGIDKPDVRFVAHLDLPRSIEGYYQETGRAGRDGLPAQAWMAWGAQDVVQQRRMI
EHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHC
DESEASEDFKRLARNRLDVLVGLVEATTCRRQHLLAYFGEESGPCGNCDNCLSPPQTWDA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
TEAARKALSCVYRTGQRYGTGHLIDVLRGERTEKVLERQHEGLSTFGIGSELDEKRWRTV
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
FRQLIAREYLAVDHERYNALALTELARPLLRGEAEFHLRLERERSKGRGKSRSAARMDIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCEECCC
GGVPTTLFDRLRAWRAATAKERNVPAYVIFHDATLREIAIARPTSMAELGGISGIGDRKL
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHCCCCCHHHHCCCCCCCCHHH
EAYGQAIVDLVAEVG
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]