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The map label for this gene is mnaA [H]

Identifier: 119899567

GI number: 119899567

Start: 3615997

End: 3617154

Strand: Reverse

Name: mnaA [H]

Synonym: azo3278

Alternate gene names: 119899567

Gene position: 3617154-3615997 (Counterclockwise)

Preceding gene: 119899568

Following gene: 119899566

Centisome position: 82.66

GC content: 66.41

Gene sequence:

>1158_bases
ATGAATGCGACCGCGACGCCCGTTGCGCCGATTGTCTGCGTGGTCGGCGCGCGGCCGAACTACATGAAGATCGCACCGAT
CATCCGGGCATTTGCGCAACACGCAACGCCACTGCCGGCGCTGCTTGTGCACACCGGCCAGCACTACGACCCGGCGATGA
AGGACCGCCTGTTCGCAGATCTCGAACTCCCGGATCCCGACGTCAACCTGGCCGTGGGCTCCGGTTCGCACGCGGTGCAG
ACCGCCGAAGTGATGAAGCGTTTCGAGCCGGTGCTCGATGAGCACGGCGCACGCGCAGTGCTGGTGGTTGGCGACGTGAA
TTCCACGCTGGCGTGCGCGCTGGTGGCCGCCAAGCGCCATATTCCTGTCGTCCACGTCGAATCCGGCTTGCGCAGCAACG
ACAGGAAAATGCCGGAGGAGATCAACCGCATCCTCACCGACCAGTTGTCGGACGTGTTGTACACCACCGAACGCAGCGCG
CATGACAACCTGGCACGCGAAGGCATTGCCCCCGAACGGGCAGTGTTTGTCGGCAACGTGATGATCGACAGTCTGCTCGC
GAGCAAGGCGAAGGCGGTGCCGCCCGCCGATTTGCTGGCTGCCGCAGGTCTTGATCCGGCCCGTATCCGGGACGGCTACG
GCGTGGTCACGCTGCACCGCCCGTCCAATGTGGACCAGCCCGAAACACTGGGTCCCATCGTGGACGCGCTGCGGGAAATC
GCAGCTCGCCTGCCTCTGGTGTTCGCGCTGCACCCGCGCACCCGTTCCAACCTGGAGCGCTTCGGTCTGGACAGTCGCCT
GGATCATCCCGGCTTCCTGGTGCTGCCGCCCCAGGGTTACCTCGAAATGCTGGGGCTGATGGCCGGGGCCAAGCTGGTGC
TGACCGATTCCGGCGGGATTCAGGAGGAGACCACGGCGTTGGGGGTGCCCTGCCTCACGATACGCGACAACACCGAACGT
CCGATCACCGTCGAGCAGGGCACCAACACCCTGGTCGGAACCGACCCGAGCGCCATCCTCGAGGCCGCCGCCGCCGTGCT
GGATGGCGGCGGCAAGGGCGGGCGGGTGCCGGAGTTGTGGGACGGTCATACCGCGGAGCGCATCGCCGCCCACCTGGCGA
ACTGGCTCGCGGAACGCGAACAACGCGAGGCCAGCTGA

Upstream 100 bases:

>100_bases
GTCTTGCAAACCTGGAGCAATCCATGTCGGCGACACTGGGCGTACTGACGCAGCTGTTGCAGGCCGTACAGCGCGAGCCG
GTGAATGGAGAGGAAAGCCA

Downstream 100 bases:

>100_bases
TGGACGCTGCCGAGGTTTCGCCGCGCGGAGAATTGACCAATGCGCTGACGATCGACGTCGAGGATTACTTCCAGGTGTCG
GCGCTGGCGCCGCATTTCCC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNATATPVAPIVCVVGARPNYMKIAPIIRAFAQHATPLPALLVHTGQHYDPAMKDRLFADLELPDPDVNLAVGSGSHAVQ
TAEVMKRFEPVLDEHGARAVLVVGDVNSTLACALVAAKRHIPVVHVESGLRSNDRKMPEEINRILTDQLSDVLYTTERSA
HDNLAREGIAPERAVFVGNVMIDSLLASKAKAVPPADLLAAAGLDPARIRDGYGVVTLHRPSNVDQPETLGPIVDALREI
AARLPLVFALHPRTRSNLERFGLDSRLDHPGFLVLPPQGYLEMLGLMAGAKLVLTDSGGIQEETTALGVPCLTIRDNTER
PITVEQGTNTLVGTDPSAILEAAAAVLDGGGKGGRVPELWDGHTAERIAAHLANWLAEREQREAS

Sequences:

>Translated_385_residues
MNATATPVAPIVCVVGARPNYMKIAPIIRAFAQHATPLPALLVHTGQHYDPAMKDRLFADLELPDPDVNLAVGSGSHAVQ
TAEVMKRFEPVLDEHGARAVLVVGDVNSTLACALVAAKRHIPVVHVESGLRSNDRKMPEEINRILTDQLSDVLYTTERSA
HDNLAREGIAPERAVFVGNVMIDSLLASKAKAVPPADLLAAAGLDPARIRDGYGVVTLHRPSNVDQPETLGPIVDALREI
AARLPLVFALHPRTRSNLERFGLDSRLDHPGFLVLPPQGYLEMLGLMAGAKLVLTDSGGIQEETTALGVPCLTIRDNTER
PITVEQGTNTLVGTDPSAILEAAAAVLDGGGKGGRVPELWDGHTAERIAAHLANWLAEREQREAS
>Mature_385_residues
MNATATPVAPIVCVVGARPNYMKIAPIIRAFAQHATPLPALLVHTGQHYDPAMKDRLFADLELPDPDVNLAVGSGSHAVQ
TAEVMKRFEPVLDEHGARAVLVVGDVNSTLACALVAAKRHIPVVHVESGLRSNDRKMPEEINRILTDQLSDVLYTTERSA
HDNLAREGIAPERAVFVGNVMIDSLLASKAKAVPPADLLAAAGLDPARIRDGYGVVTLHRPSNVDQPETLGPIVDALREI
AARLPLVFALHPRTRSNLERFGLDSRLDHPGFLVLPPQGYLEMLGLMAGAKLVLTDSGGIQEETTALGVPCLTIRDNTER
PITVEQGTNTLVGTDPSAILEAAAAVLDGGGKGGRVPELWDGHTAERIAAHLANWLAEREQREAS

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=382, Percent_Identity=34.0314136125654, Blast_Score=148, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41191; Mature: 41191

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATATPVAPIVCVVGARPNYMKIAPIIRAFAQHATPLPALLVHTGQHYDPAMKDRLFAD
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHEEE
LELPDPDVNLAVGSGSHAVQTAEVMKRFEPVLDEHGARAVLVVGDVNSTLACALVAAKRH
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHC
IPVVHVESGLRSNDRKMPEEINRILTDQLSDVLYTTERSAHDNLAREGIAPERAVFVGNV
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHEEEHHH
MIDSLLASKAKAVPPADLLAAAGLDPARIRDGYGVVTLHRPSNVDQPETLGPIVDALREI
HHHHHHHHHHCCCCCHHHHHHCCCCHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
AARLPLVFALHPRTRSNLERFGLDSRLDHPGFLVLPPQGYLEMLGLMAGAKLVLTDSGGI
HHHCCEEEEECCCHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHCCCEEEEECCCCC
QEETTALGVPCLTIRDNTERPITVEQGTNTLVGTDPSAILEAAAAVLDGGGKGGRVPELW
CCHHHHHCCCEEEEECCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCC
DGHTAERIAAHLANWLAEREQREAS
CCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNATATPVAPIVCVVGARPNYMKIAPIIRAFAQHATPLPALLVHTGQHYDPAMKDRLFAD
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHEEE
LELPDPDVNLAVGSGSHAVQTAEVMKRFEPVLDEHGARAVLVVGDVNSTLACALVAAKRH
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHC
IPVVHVESGLRSNDRKMPEEINRILTDQLSDVLYTTERSAHDNLAREGIAPERAVFVGNV
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHEEEHHH
MIDSLLASKAKAVPPADLLAAAGLDPARIRDGYGVVTLHRPSNVDQPETLGPIVDALREI
HHHHHHHHHHCCCCCHHHHHHCCCCHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
AARLPLVFALHPRTRSNLERFGLDSRLDHPGFLVLPPQGYLEMLGLMAGAKLVLTDSGGI
HHHCCEEEEECCCHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHCCCEEEEECCCCC
QEETTALGVPCLTIRDNTERPITVEQGTNTLVGTDPSAILEAAAAVLDGGGKGGRVPELW
CCHHHHHCCCEEEEECCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCC
DGHTAERIAAHLANWLAEREQREAS
CCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]