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The map label for this gene is folB [H]

Identifier: 119899511

GI number: 119899511

Start: 3552711

End: 3553088

Strand: Reverse

Name: folB [H]

Synonym: azo3222

Alternate gene names: 119899511

Gene position: 3553088-3552711 (Counterclockwise)

Preceding gene: 119899513

Following gene: 119899502

Centisome position: 81.19

GC content: 59.79

Gene sequence:

>378_bases
ATGGATTTCATCTTCATCGAGGAGTTGCGGGTGCAGGCGTGGGTGGGAATCTACGCCCGTGAAAAAGCTGCGCCGCAAAC
CGTCGAACTCAACCTCACCTTCGGTGTTCCCGACGCGGCGGCGGAGCACGACGACATCGCCGACACCATCAACTATGCCG
AAGTGATAGAGCGCATCCGTGCGGAATTGGCGGGGCGGCATTTCAATTTGATCGAGACGCTGGGCGAGTTCGTCGTGGCG
TTACTGTTCGACGAATTCGGTGCGCCCTGGGTGAAAATACGGATTGCCAAAATCGGCGTAATGAAAGGCGTCCGCCGCGT
GGGGGTGTTCATACAGCGCGGGCGGGAGGGCGTTTCGCTTCCGGCTGGTCCGCTGTGA

Upstream 100 bases:

>100_bases
GAAAGGCGGGGCGTGGAGTCCCGGTGTGGCGCGTGTTGCGTAATCTGCGGACAGCGCGCCATCCGGGATAAAATCCGTCC
GATTCTAATCGGGAACCTGC

Downstream 100 bases:

>100_bases
TGCAGGCCCGGTGAAAAACACAATGCCGCCTTTAGGGCGGCATTGTGTTTCACTTCGGGCGCGGTGCCCGTCGCAGTAAT
GCGGCGAATATCAAACCGCC

Product: FolB protein

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MDFIFIEELRVQAWVGIYAREKAAPQTVELNLTFGVPDAAAEHDDIADTINYAEVIERIRAELAGRHFNLIETLGEFVVA
LLFDEFGAPWVKIRIAKIGVMKGVRRVGVFIQRGREGVSLPAGPL

Sequences:

>Translated_125_residues
MDFIFIEELRVQAWVGIYAREKAAPQTVELNLTFGVPDAAAEHDDIADTINYAEVIERIRAELAGRHFNLIETLGEFVVA
LLFDEFGAPWVKIRIAKIGVMKGVRRVGVFIQRGREGVSLPAGPL
>Mature_125_residues
MDFIFIEELRVQAWVGIYAREKAAPQTVELNLTFGVPDAAAEHDDIADTINYAEVIERIRAELAGRHFNLIETLGEFVVA
LLFDEFGAPWVKIRIAKIGVMKGVRRVGVFIQRGREGVSLPAGPL

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimeriza

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=120, Percent_Identity=38.3333333333333, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13921; Mature: 13921

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFIFIEELRVQAWVGIYAREKAAPQTVELNLTFGVPDAAAEHDDIADTINYAEVIERIR
CCEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
AELAGRHFNLIETLGEFVVALLFDEFGAPWVKIRIAKIGVMKGVRRVGVFIQRGREGVSL
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
PAGPL
CCCCC
>Mature Secondary Structure
MDFIFIEELRVQAWVGIYAREKAAPQTVELNLTFGVPDAAAEHDDIADTINYAEVIERIR
CCEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
AELAGRHFNLIETLGEFVVALLFDEFGAPWVKIRIAKIGVMKGVRRVGVFIQRGREGVSL
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
PAGPL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]