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The map label for this gene is qor [H]

Identifier: 119899498

GI number: 119899498

Start: 3536117

End: 3537091

Strand: Reverse

Name: qor [H]

Synonym: azo3209

Alternate gene names: 119899498

Gene position: 3537091-3536117 (Counterclockwise)

Preceding gene: 119899499

Following gene: 119899497

Centisome position: 80.83

GC content: 70.26

Gene sequence:

>975_bases
ATGACCCATGCCATCCGCTTCCACCAGACGGGCGGTCCCGAAGTGCTGCAGTGGGAGGAGGTCGAGCCGGGTGCGCCGGC
AGCTGGTGAGGCCCGCATCCGCCAGCATGCGGTCGGGCTCAATTTCATCGACACCTACCACCGCTCCGGCCTGTACCCGG
TGCCGCTGCCCTCCGGGCTGGGCAGCGAGGGCGCCGGCGTGGTCGAGGCCGTGGGCGAGGGCGTGACCGACCTCGCCGTG
GGCGACCGCGTGGCCTACGCCACCGGGCCGCTCGGCGCCTATGCCGAGGTGCGCAACCTGCCGGCCGACCGCCTGGTGAA
GCTGCCGGACGCGATCAGCTTCGAGCAGGGCGCGGCGGCGATGCTGCAGGGCCTGACCGTGCAGTACCTGCTGCGCCGCA
CCTACCGCGTGCAGGCGGGCGACACCATCCTGATCCACGCCGCGGCCGGCGGCGTCGGCACCATCGTGTGCCAGTGGGCG
AAGGCGCTCGGTGCCACGGTCATCGGCACCGTGGGGTCGGACGAGAAGGCCGCGCTCGCACGTGCCCACGGCTGCGACCA
TCCCATCGTCTATACCCGCGAGAACTTCGCCGAGCGGGTGCGCGAGATCACCGGTGGAGAGGGGCTGCCGGTGGTGTACG
ACTCGATCGGCAAGGACACTTTCATGGACTCGCTGTCCTGCCTGCGACCGCTCGGCATGATGGTGCTGTTCGGCGCCTCG
TCCGGCCCGGTGCCGCCGTTCGACTGCGGCGTGCTCGCCAAGATGGGCTCGCTGTTCCTGACCCGGCCGTCGCTCTTCAC
CTACGCGGCCAAGCGCGCCGACCTGCTGGCGATGGCGGACGAGTTGTTCGAGGCGATCATCAGCGGCAAGGTGAAGATCG
AGATCAACCAGCGCTATGCGCTCAAGGACGCCGCACAGGCGCACCGTGACCTGGAAGCGCGCCGGACCACAGGCTCCACC
GTCCTGCTGCCGTAA

Upstream 100 bases:

>100_bases
CTATGGCGAAACCCTGCTGGACTACAACGAGGCGCGTTCGCCGCAGATTAGAATCGGCCTTTCCCTCGTCAGATGAGCGC
CGCGGGCGCAAGGAGATCCC

Downstream 100 bases:

>100_bases
TCGTCCCTGCCGGGGCCGTCGTCCGCGCCGGGCGGGCGGCTGCCTCGGGTAAAATCCGCGGATGAACGCCGCACATCCTG
CTCCTCACGAGCCCCGCTTC

Product: NADPH:quinone reductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTHAIRFHQTGGPEVLQWEEVEPGAPAAGEARIRQHAVGLNFIDTYHRSGLYPVPLPSGLGSEGAGVVEAVGEGVTDLAV
GDRVAYATGPLGAYAEVRNLPADRLVKLPDAISFEQGAAAMLQGLTVQYLLRRTYRVQAGDTILIHAAAGGVGTIVCQWA
KALGATVIGTVGSDEKAALARAHGCDHPIVYTRENFAERVREITGGEGLPVVYDSIGKDTFMDSLSCLRPLGMMVLFGAS
SGPVPPFDCGVLAKMGSLFLTRPSLFTYAAKRADLLAMADELFEAIISGKVKIEINQRYALKDAAQAHRDLEARRTTGST
VLLP

Sequences:

>Translated_324_residues
MTHAIRFHQTGGPEVLQWEEVEPGAPAAGEARIRQHAVGLNFIDTYHRSGLYPVPLPSGLGSEGAGVVEAVGEGVTDLAV
GDRVAYATGPLGAYAEVRNLPADRLVKLPDAISFEQGAAAMLQGLTVQYLLRRTYRVQAGDTILIHAAAGGVGTIVCQWA
KALGATVIGTVGSDEKAALARAHGCDHPIVYTRENFAERVREITGGEGLPVVYDSIGKDTFMDSLSCLRPLGMMVLFGAS
SGPVPPFDCGVLAKMGSLFLTRPSLFTYAAKRADLLAMADELFEAIISGKVKIEINQRYALKDAAQAHRDLEARRTTGST
VLLP
>Mature_323_residues
THAIRFHQTGGPEVLQWEEVEPGAPAAGEARIRQHAVGLNFIDTYHRSGLYPVPLPSGLGSEGAGVVEAVGEGVTDLAVG
DRVAYATGPLGAYAEVRNLPADRLVKLPDAISFEQGAAAMLQGLTVQYLLRRTYRVQAGDTILIHAAAGGVGTIVCQWAK
ALGATVIGTVGSDEKAALARAHGCDHPIVYTRENFAERVREITGGEGLPVVYDSIGKDTFMDSLSCLRPLGMMVLFGASS
GPVPPFDCGVLAKMGSLFLTRPSLFTYAAKRADLLAMADELFEAIISGKVKIEINQRYALKDAAQAHRDLEARRTTGSTV
LLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=31.306990881459, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=31.306990881459, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=30.3225806451613, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=32.5301204819277, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=32.5301204819277, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI194239676, Length=213, Percent_Identity=37.0892018779343, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI24308257, Length=221, Percent_Identity=35.2941176470588, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI28557745, Length=286, Percent_Identity=29.7202797202797, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI197927207, Length=189, Percent_Identity=26.4550264550265, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI226059159, Length=140, Percent_Identity=33.5714285714286, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI226059133, Length=140, Percent_Identity=33.5714285714286, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=53.5168195718654, Blast_Score=342, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17507255, Length=306, Percent_Identity=26.797385620915, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17556000, Length=262, Percent_Identity=29.7709923664122, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536829, Length=310, Percent_Identity=26.7741935483871, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI133901712, Length=292, Percent_Identity=28.0821917808219, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI133901710, Length=292, Percent_Identity=28.0821917808219, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=36.1111111111111, Blast_Score=202, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6323729, Length=318, Percent_Identity=24.8427672955975, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=319, Percent_Identity=26.3322884012539, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=320, Percent_Identity=24.0625, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34398; Mature: 34267

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHAIRFHQTGGPEVLQWEEVEPGAPAAGEARIRQHAVGLNFIDTYHRSGLYPVPLPSGL
CCCEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
GSEGAGVVEAVGEGVTDLAVGDRVAYATGPLGAYAEVRNLPADRLVKLPDAISFEQGAAA
CCCCCHHHHHHCCCCHHHHHCCEEEEECCCCCHHHHHHCCCHHHHCCCCCCCCCCHHHHH
MLQGLTVQYLLRRTYRVQAGDTILIHAAAGGVGTIVCQWAKALGATVIGTVGSDEKAALA
HHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHH
RAHGCDHPIVYTRENFAERVREITGGEGLPVVYDSIGKDTFMDSLSCLRPLGMMVLFGAS
HHCCCCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCEEEEECCC
SGPVPPFDCGVLAKMGSLFLTRPSLFTYAAKRADLLAMADELFEAIISGKVKIEINQRYA
CCCCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHH
LKDAAQAHRDLEARRTTGSTVLLP
HHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
THAIRFHQTGGPEVLQWEEVEPGAPAAGEARIRQHAVGLNFIDTYHRSGLYPVPLPSGL
CCEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
GSEGAGVVEAVGEGVTDLAVGDRVAYATGPLGAYAEVRNLPADRLVKLPDAISFEQGAAA
CCCCCHHHHHHCCCCHHHHHCCEEEEECCCCCHHHHHHCCCHHHHCCCCCCCCCCHHHHH
MLQGLTVQYLLRRTYRVQAGDTILIHAAAGGVGTIVCQWAKALGATVIGTVGSDEKAALA
HHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHH
RAHGCDHPIVYTRENFAERVREITGGEGLPVVYDSIGKDTFMDSLSCLRPLGMMVLFGAS
HHCCCCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCEEEEECCC
SGPVPPFDCGVLAKMGSLFLTRPSLFTYAAKRADLLAMADELFEAIISGKVKIEINQRYA
CCCCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHH
LKDAAQAHRDLEARRTTGSTVLLP
HHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]