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The map label for this gene is adiA [H]

Identifier: 119899488

GI number: 119899488

Start: 3520046

End: 3522289

Strand: Reverse

Name: adiA [H]

Synonym: azo3199

Alternate gene names: 119899488

Gene position: 3522289-3520046 (Counterclockwise)

Preceding gene: 119899489

Following gene: 119899485

Centisome position: 80.49

GC content: 62.97

Gene sequence:

>2244_bases
ATGCGATTCCATTTTCCGATCATCATCATCGACGAGGACTTCCGCTCCGAGAACACCTCGGGGCTGGGCATCCGCGCGCT
CGCCACAGCCATCGAGGAAGAGGGCATGGAGGTGCTCGGGGTCACGAGCTACGGCGACCTGACCTCTTTCGCCCAGCAGC
AGAGCCGCGGTTCGGGCTTCATCCTGTCGATCGACGATGAAGAGTTTTCCTCGCCCGAGGCCTCGGCCAAGGCAATTGCC
GACCTGCGCAGCTTCGTCGAGGAGATCCGCCTGCGCAACGCCGACATCCCGATCTTCCTGCACGGGGAGACGCGCACCAG
CCGTCATATTCCGAACGATGTGCTGCGCGAGATGCACGGCTTCATCCACATGTTCGAGGACACGCCGGAGTTCATCGCGC
GCTACGTCGTGCGCGAGGCGCGCAACTACCTCGAGTCGCTGCCGCCGCCGTTCTTCCGCGCGCTGACGCACTACGCGGCG
GACGGCTCGTATTCCTGGCACTGCCCGGGCCATTCCGGGGGCGTCGCGTTCCTGAAGAGTCCGGTCGGGCAGATGTTCCA
CCAGTTCTTCGGCGAGAACATGCTGCGGGCGGACGTCTGCAACGCGGTGGATGAACTCGGCCAGTTGCTCGACCACACCG
GCCCGGTGGCTGCGTCCGAGCGTAACGCGGCGCGCATCTTCAACTGCGATCACCTGTACTTCGTCACCAACGGCACTTCG
ACCTCGAACAAGATGGTGTGGCACACCACGGTGGCGCCCGGCGACATCGTCGTCGTCGACCGCAACTGCCACAAGTCCAT
CCTGCACTCCATCATCATGACCGGCGCGGTGCCGGTGTTCCTGACGCCGACCCGCAACCACTACGGCATCATCGGCCCGA
TCCCGCTGGAGGAGTTCTCGATGGAGAACATCCAGAAGAAGATCGAGGCCAACCCGTTCGCACGCGAAGCGAAGAGCAAG
AAGCCGCGCATCCTCACCATCACCCAGTCGACTTACGACGGCGTGGTGTACAACGTCGAGACCATCAAGGAGATGCTCGA
CGGCAAGATCGACACGCTGCACTTCGATGAAGCCTGGCTGCCGCACGCGGCCTTCCACGACTTCTACGGCGACTACCACG
CGATCGGCGAGGATCGTCCGCGCTGCCGCGAGTCGATGATCTTCTCGACGCAATCGACCCACAAGCTGCTCGCCGGCCTC
AGCCAAGCGTCGCAGATCCTCGTGCAGGACTCGCAGACCCGCAAGCTCGACCGCGACATCTTCAACGAGGCCTATCTGAT
GCACACCTCCACCTCGCCGCAGTACGCGATCATCGCGTCCTGCGACGTGGCGGCGGCGATGATGGAGCCGCCGGGCGGTG
CCGCGCTGGTGGATGAATCACTGGCGGAGGCGGTCGAGTTCCGCCGTGCGATGCGCAAGGTGGATGCCGAGTTCGGCGAA
TCCGACTGGTGGTTCCGGGTGTGGGGCCCGGAGTATCTCGCCGAGGAAGGCCTGGGCGAGCGTGACGACTGGATGCTGAA
GAACGGCGAACGCTGGCACGGTTTCGGTGATCTGGCGCCGGGCTTCAACATGCTGGATCCGATCAAGGCTACCGTGATCA
CGCCGGGGCTGGATGTGGATGGCGACTTTGCCGACTGGGGAATCCCGGCGGGCATCCTCACGCGCTACCTGGCCGAGCAC
GGGATCATCGTCGAGAAGACCGGGCTGTATTCGTTCTTCATCATGTTCACGATCGGTATCACCAAGGGGCGCTGGAACAC
GTTGGTGACCGAACTCCAGCAGTTCAAGGACGACTACGATCGCAACCAGCCTTTGTGGCGCGTGATGCCGGACTTCATTG
CCAAGCATCCGCGCTACGAGAAAGTGGGGTTGAAGGACCTGTGCGCGCAGATCCACAGCTTCTACAAGGCCCACGACGTG
GCACGGCTGACCACCGAGATGTACCTGTCGGACATGGTGCCCGCGATGAAACCGGCCGACGCCTTCGCCAAGATGGCGCA
CCGTGAAATCGAACGGGTTCTGATCGACGAACTGGAGGATCGCGTCACCGCGATGCTGGTAACGCCGTATCCGCCGGGTA
TTCCCCTGCTAATTCCGGGCGAGCGCTTCAATCCGACGATCGTGCGCTATCTGCAGTTCGCACGCGATTTCAACGCCCGC
TTCCCCGGGTTCGAAACCGACATCCACGGGCTGGTGAAGGGAGACGACGGCCGTTACTACGTGGATTGCGTAGCGGCAGA
CTAG

Upstream 100 bases:

>100_bases
CGTCAGTCGGCCCTTTTCTACTTCTGCCGACGTCGCGTAAACAACACGCGTTTAAGATGCACGGCAGTCCCGCACGGGAC
GGCTGCTGGAGAGACCAAGG

Downstream 100 bases:

>100_bases
ATCGGTATCGGTGCAGACACTACGGCCCCCTAGGGGCCGTAGTCGTTTAGCGGCGGCGGTAGTCGACGATGTCGAACGCG
AATTGGTTGTCGGCATCCGC

Product: putative Orn/Arg/Lys decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MRFHFPIIIIDEDFRSENTSGLGIRALATAIEEEGMEVLGVTSYGDLTSFAQQQSRGSGFILSIDDEEFSSPEASAKAIA
DLRSFVEEIRLRNADIPIFLHGETRTSRHIPNDVLREMHGFIHMFEDTPEFIARYVVREARNYLESLPPPFFRALTHYAA
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLYFVTNGTS
TSNKMVWHTTVAPGDIVVVDRNCHKSILHSIIMTGAVPVFLTPTRNHYGIIGPIPLEEFSMENIQKKIEANPFAREAKSK
KPRILTITQSTYDGVVYNVETIKEMLDGKIDTLHFDEAWLPHAAFHDFYGDYHAIGEDRPRCRESMIFSTQSTHKLLAGL
SQASQILVQDSQTRKLDRDIFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGAALVDESLAEAVEFRRAMRKVDAEFGE
SDWWFRVWGPEYLAEEGLGERDDWMLKNGERWHGFGDLAPGFNMLDPIKATVITPGLDVDGDFADWGIPAGILTRYLAEH
GIIVEKTGLYSFFIMFTIGITKGRWNTLVTELQQFKDDYDRNQPLWRVMPDFIAKHPRYEKVGLKDLCAQIHSFYKAHDV
ARLTTEMYLSDMVPAMKPADAFAKMAHREIERVLIDELEDRVTAMLVTPYPPGIPLLIPGERFNPTIVRYLQFARDFNAR
FPGFETDIHGLVKGDDGRYYVDCVAAD

Sequences:

>Translated_747_residues
MRFHFPIIIIDEDFRSENTSGLGIRALATAIEEEGMEVLGVTSYGDLTSFAQQQSRGSGFILSIDDEEFSSPEASAKAIA
DLRSFVEEIRLRNADIPIFLHGETRTSRHIPNDVLREMHGFIHMFEDTPEFIARYVVREARNYLESLPPPFFRALTHYAA
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLYFVTNGTS
TSNKMVWHTTVAPGDIVVVDRNCHKSILHSIIMTGAVPVFLTPTRNHYGIIGPIPLEEFSMENIQKKIEANPFAREAKSK
KPRILTITQSTYDGVVYNVETIKEMLDGKIDTLHFDEAWLPHAAFHDFYGDYHAIGEDRPRCRESMIFSTQSTHKLLAGL
SQASQILVQDSQTRKLDRDIFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGAALVDESLAEAVEFRRAMRKVDAEFGE
SDWWFRVWGPEYLAEEGLGERDDWMLKNGERWHGFGDLAPGFNMLDPIKATVITPGLDVDGDFADWGIPAGILTRYLAEH
GIIVEKTGLYSFFIMFTIGITKGRWNTLVTELQQFKDDYDRNQPLWRVMPDFIAKHPRYEKVGLKDLCAQIHSFYKAHDV
ARLTTEMYLSDMVPAMKPADAFAKMAHREIERVLIDELEDRVTAMLVTPYPPGIPLLIPGERFNPTIVRYLQFARDFNAR
FPGFETDIHGLVKGDDGRYYVDCVAAD
>Mature_747_residues
MRFHFPIIIIDEDFRSENTSGLGIRALATAIEEEGMEVLGVTSYGDLTSFAQQQSRGSGFILSIDDEEFSSPEASAKAIA
DLRSFVEEIRLRNADIPIFLHGETRTSRHIPNDVLREMHGFIHMFEDTPEFIARYVVREARNYLESLPPPFFRALTHYAA
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLYFVTNGTS
TSNKMVWHTTVAPGDIVVVDRNCHKSILHSIIMTGAVPVFLTPTRNHYGIIGPIPLEEFSMENIQKKIEANPFAREAKSK
KPRILTITQSTYDGVVYNVETIKEMLDGKIDTLHFDEAWLPHAAFHDFYGDYHAIGEDRPRCRESMIFSTQSTHKLLAGL
SQASQILVQDSQTRKLDRDIFNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGAALVDESLAEAVEFRRAMRKVDAEFGE
SDWWFRVWGPEYLAEEGLGERDDWMLKNGERWHGFGDLAPGFNMLDPIKATVITPGLDVDGDFADWGIPAGILTRYLAEH
GIIVEKTGLYSFFIMFTIGITKGRWNTLVTELQQFKDDYDRNQPLWRVMPDFIAKHPRYEKVGLKDLCAQIHSFYKAHDV
ARLTTEMYLSDMVPAMKPADAFAKMAHREIERVLIDELEDRVTAMLVTPYPPGIPLLIPGERFNPTIVRYLQFARDFNAR
FPGFETDIHGLVKGDDGRYYVDCVAAD

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=762, Percent_Identity=37.2703412073491, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1790573, Length=728, Percent_Identity=36.9505494505495, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1786384, Length=725, Percent_Identity=37.9310344827586, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1786909, Length=676, Percent_Identity=32.9881656804734, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI87082193, Length=719, Percent_Identity=32.4061196105702, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 84366; Mature: 84366

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFHFPIIIIDEDFRSENTSGLGIRALATAIEEEGMEVLGVTSYGDLTSFAQQQSRGSGF
CEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEE
ILSIDDEEFSSPEASAKAIADLRSFVEEIRLRNADIPIFLHGETRTSRHIPNDVLREMHG
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHH
FIHMFEDTPEFIARYVVREARNYLESLPPPFFRALTHYAADGSYSWHCPGHSGGVAFLKS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHHHH
PVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLYFVTNGTS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCC
TSNKMVWHTTVAPGDIVVVDRNCHKSILHSIIMTGAVPVFLTPTRNHYGIIGPIPLEEFS
CCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCHHHHH
MENIQKKIEANPFAREAKSKKPRILTITQSTYDGVVYNVETIKEMLDGKIDTLHFDEAWL
HHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHHCCCCCEEECCCCCC
PHAAFHDFYGDYHAIGEDRPRCRESMIFSTQSTHKLLAGLSQASQILVQDSQTRKLDRDI
CHHHHHHHCCCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGAALVDESLAEAVEFRRAMRKVDAEFGE
HCCEEEEEECCCCCEEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SDWWFRVWGPEYLAEEGLGERDDWMLKNGERWHGFGDLAPGFNMLDPIKATVITPGLDVD
CCCEEEECCHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCC
GDFADWGIPAGILTRYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNTLVTELQQFKDDYD
CCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
RNQPLWRVMPDFIAKHPRYEKVGLKDLCAQIHSFYKAHDVARLTTEMYLSDMVPAMKPAD
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AFAKMAHREIERVLIDELEDRVTAMLVTPYPPGIPLLIPGERFNPTIVRYLQFARDFNAR
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCC
FPGFETDIHGLVKGDDGRYYVDCVAAD
CCCCCCCCCEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MRFHFPIIIIDEDFRSENTSGLGIRALATAIEEEGMEVLGVTSYGDLTSFAQQQSRGSGF
CEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCEE
ILSIDDEEFSSPEASAKAIADLRSFVEEIRLRNADIPIFLHGETRTSRHIPNDVLREMHG
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHH
FIHMFEDTPEFIARYVVREARNYLESLPPPFFRALTHYAADGSYSWHCPGHSGGVAFLKS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHHHH
PVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFNCDHLYFVTNGTS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCC
TSNKMVWHTTVAPGDIVVVDRNCHKSILHSIIMTGAVPVFLTPTRNHYGIIGPIPLEEFS
CCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCHHHHH
MENIQKKIEANPFAREAKSKKPRILTITQSTYDGVVYNVETIKEMLDGKIDTLHFDEAWL
HHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHHCCCCCEEECCCCCC
PHAAFHDFYGDYHAIGEDRPRCRESMIFSTQSTHKLLAGLSQASQILVQDSQTRKLDRDI
CHHHHHHHCCCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FNEAYLMHTSTSPQYAIIASCDVAAAMMEPPGGAALVDESLAEAVEFRRAMRKVDAEFGE
HCCEEEEEECCCCCEEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SDWWFRVWGPEYLAEEGLGERDDWMLKNGERWHGFGDLAPGFNMLDPIKATVITPGLDVD
CCCEEEECCHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCC
GDFADWGIPAGILTRYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNTLVTELQQFKDDYD
CCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
RNQPLWRVMPDFIAKHPRYEKVGLKDLCAQIHSFYKAHDVARLTTEMYLSDMVPAMKPAD
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AFAKMAHREIERVLIDELEDRVTAMLVTPYPPGIPLLIPGERFNPTIVRYLQFARDFNAR
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCC
FPGFETDIHGLVKGDDGRYYVDCVAAD
CCCCCCCCCEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]