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The map label for this gene is queD [H]

Identifier: 119899408

GI number: 119899408

Start: 3425991

End: 3426446

Strand: Direct

Name: queD [H]

Synonym: azo3118

Alternate gene names: 119899408

Gene position: 3425991-3426446 (Clockwise)

Preceding gene: 119899406

Following gene: 119899416

Centisome position: 78.29

GC content: 65.35

Gene sequence:

>456_bases
ATGCGCATCACCCGTCGGCTGGAATTCGACGCCGGCCATCGCATTCCGGATCACGCGAGCCAGTGCCGGCACTTGCACGG
CCACCGTTACGCCATCGAGGTCACGCTGTCGGGTGAGATCATCGACGCCGCGGGCCAGCCGGTCAATGGCATGGTGATGG
ACTTCGGCGAAGTGAAGCGGCTGGCGGCCGAGCACATCGTCAGCGTGTGGGACCACGCTTTCCTGGTCTACCGCGGCGAC
ACCCAGGTTGCGGACTTTCTTGCCTCGATGCCGGGCCACAAGACGGTGGTGCTCGACGTGGTGCCGACCGCCGAAAACCT
CGCCGCGCTCGCCTTCCGCATCCTCGATCCGGTGTATGCCGACAGCTACGGCAACCACCTGCGGCTGGAGCGGGTTCGAC
TGTACGAAACGCCCAACTGCTGGGCCGACGCAATCCGCAGCGAACTGCCTGACTGA

Upstream 100 bases:

>100_bases
GCGTTGGAATCCATCGTGACATCAGGGACTTGGAGGAAATGGCGGCGGAACGCGGACAGCGCGGTGTTATACTCGCCGCC
CGTCATGACGAGGCAGCATC

Downstream 100 bases:

>100_bases
AAACGGAGCGACGGAGGGAGGCTGATGCCTCCCCACGACGCCCCGTCGATCCGGCTCAAACCGCGTAGCGCCGCAGCCGC
AACGAGAAGTCCTGCAGTTG

Product: 6-pyruvoyltetrahydropterin synthase

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MRITRRLEFDAGHRIPDHASQCRHLHGHRYAIEVTLSGEIIDAAGQPVNGMVMDFGEVKRLAAEHIVSVWDHAFLVYRGD
TQVADFLASMPGHKTVVLDVVPTAENLAALAFRILDPVYADSYGNHLRLERVRLYETPNCWADAIRSELPD

Sequences:

>Translated_151_residues
MRITRRLEFDAGHRIPDHASQCRHLHGHRYAIEVTLSGEIIDAAGQPVNGMVMDFGEVKRLAAEHIVSVWDHAFLVYRGD
TQVADFLASMPGHKTVVLDVVPTAENLAALAFRILDPVYADSYGNHLRLERVRLYETPNCWADAIRSELPD
>Mature_151_residues
MRITRRLEFDAGHRIPDHASQCRHLHGHRYAIEVTLSGEIIDAAGQPVNGMVMDFGEVKRLAAEHIVSVWDHAFLVYRGD
TQVADFLASMPGHKTVVLDVVPTAENLAALAFRILDPVYADSYGNHLRLERVRLYETPNCWADAIRSELPD

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 16987; Mature: 16987

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITRRLEFDAGHRIPDHASQCRHLHGHRYAIEVTLSGEIIDAAGQPVNGMVMDFGEVKR
CCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEECCEEEECCCCCCCCEEECHHHHHH
LAAEHIVSVWDHAFLVYRGDTQVADFLASMPGHKTVVLDVVPTAENLAALAFRILDPVYA
HHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
DSYGNHLRLERVRLYETPNCWADAIRSELPD
CCCCCEEEEEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRITRRLEFDAGHRIPDHASQCRHLHGHRYAIEVTLSGEIIDAAGQPVNGMVMDFGEVKR
CCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEECCEEEECCCCCCCCEEECHHHHHH
LAAEHIVSVWDHAFLVYRGDTQVADFLASMPGHKTVVLDVVPTAENLAALAFRILDPVYA
HHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
DSYGNHLRLERVRLYETPNCWADAIRSELPD
CCCCCEEEEEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA