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The map label for this gene is flp [H]

Identifier: 119899374

GI number: 119899374

Start: 3393105

End: 3393806

Strand: Direct

Name: flp [H]

Synonym: azo3084

Alternate gene names: 119899374

Gene position: 3393105-3393806 (Clockwise)

Preceding gene: 119899372

Following gene: 119899378

Centisome position: 77.54

GC content: 68.09

Gene sequence:

>702_bases
ATGGCCGGAGACCTTCCCCAACCTTCCCCCGCCCTGATTGCGCAGCTGCGCCAGGTGCCGCTGTTTTCCGAACTCGCCGA
CGAGGATATCGCAAGCATCGCCCGCCACAGCCGCGAACGCAGCGTGGCGCGCGGCGAGATGCTGTTCCAGCGCGGCGACA
CGCCGCGCGGCTTCTTCTGTGTGCTGCGCGGCCAGATCAAGCTGGCGTTTTCTTCGGCCGCCGGCAACGAGAAGGTGGTC
GAGGTGATCGGCGCCGGGCAGAGCTTTGGCGAGGCGGTGATGTTCATGGAGCGGCCCTACCCGGTGTTCGCCGAGGCGCT
GATGGACAGCACGCTGCTGGCGATCGGCCAGGAGGTGCTGCTCGGCCAGCTCGACGACAACCCGCGCTTTGCGCGCAAGC
TGCTGGCGGGGCTGTCGATCCGGCTGCACAGCCTGGTGCGCGACGTGGAGACCTACACGCTGCGCTCCAGCATGCAGCGC
GTCATCGGCTACCTGCTGCAGCAGACGCCGGAAGACCTCGACGCCGGCGAATGCCGCATCGACCTGCCGACCAGCAAGCA
GGTGATCGCCTCGCGCCTCAACCTCACGCCCGAAACCCTGTCGCGCATCTTTCACGACCTTGCCGAGGCGCGGCTGATCA
CCGTGGCGGGCAAGCGCATCACGCTGCACGACATCCGCCGCCTGCGCGCGCACGAAGGCTGA

Upstream 100 bases:

>100_bases
TGTACATTCGATCGTTCTCCGGGGGGATGCGGCGGTGCCGCGGGCGGGTGCCAGGGGCGATGGGCTAGAATCCAGACATA
CCCACAACAGGCTTGCCCCG

Downstream 100 bases:

>100_bases
TCCGCGCCGCGCGCGGGTTCAGCCGGGCTGGCGGGCCGGTTCGGCACCCGCCCCGGCGGCCAGATACACCTTCAGCGCGC
CACCCAAGTTGGCGGCGAGC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MAGDLPQPSPALIAQLRQVPLFSELADEDIASIARHSRERSVARGEMLFQRGDTPRGFFCVLRGQIKLAFSSAAGNEKVV
EVIGAGQSFGEAVMFMERPYPVFAEALMDSTLLAIGQEVLLGQLDDNPRFARKLLAGLSIRLHSLVRDVETYTLRSSMQR
VIGYLLQQTPEDLDAGECRIDLPTSKQVIASRLNLTPETLSRIFHDLAEARLITVAGKRITLHDIRRLRAHEG

Sequences:

>Translated_233_residues
MAGDLPQPSPALIAQLRQVPLFSELADEDIASIARHSRERSVARGEMLFQRGDTPRGFFCVLRGQIKLAFSSAAGNEKVV
EVIGAGQSFGEAVMFMERPYPVFAEALMDSTLLAIGQEVLLGQLDDNPRFARKLLAGLSIRLHSLVRDVETYTLRSSMQR
VIGYLLQQTPEDLDAGECRIDLPTSKQVIASRLNLTPETLSRIFHDLAEARLITVAGKRITLHDIRRLRAHEG
>Mature_232_residues
AGDLPQPSPALIAQLRQVPLFSELADEDIASIARHSRERSVARGEMLFQRGDTPRGFFCVLRGQIKLAFSSAAGNEKVVE
VIGAGQSFGEAVMFMERPYPVFAEALMDSTLLAIGQEVLLGQLDDNPRFARKLLAGLSIRLHSLVRDVETYTLRSSMQRV
IGYLLQQTPEDLDAGECRIDLPTSKQVIASRLNLTPETLSRIFHDLAEARLITVAGKRITLHDIRRLRAHEG

Specific function: Global Transcription Factor That Controls The Expression Of Over 100 Target Genes In Response To Anoxia. It Facilitates The Adaptation To Anaerobic Growth Conditions By Regulating The Expression Of Gene Products That Are Involved In Anaerobic Energy Metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25834; Mature: 25703

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGDLPQPSPALIAQLRQVPLFSELADEDIASIARHSRERSVARGEMLFQRGDTPRGFFC
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
VLRGQIKLAFSSAAGNEKVVEVIGAGQSFGEAVMFMERPYPVFAEALMDSTLLAIGQEVL
EEECCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LGQLDDNPRFARKLLAGLSIRLHSLVRDVETYTLRSSMQRVIGYLLQQTPEDLDAGECRI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
DLPTSKQVIASRLNLTPETLSRIFHDLAEARLITVAGKRITLHDIRRLRAHEG
ECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCEEHHHHHHHHHHCCC
>Mature Secondary Structure 
AGDLPQPSPALIAQLRQVPLFSELADEDIASIARHSRERSVARGEMLFQRGDTPRGFFC
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
VLRGQIKLAFSSAAGNEKVVEVIGAGQSFGEAVMFMERPYPVFAEALMDSTLLAIGQEVL
EEECCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LGQLDDNPRFARKLLAGLSIRLHSLVRDVETYTLRSSMQRVIGYLLQQTPEDLDAGECRI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
DLPTSKQVIASRLNLTPETLSRIFHDLAEARLITVAGKRITLHDIRRLRAHEG
ECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2113923; 8441692 [H]